ATE302021T1 - Gefriergetrocknete zusammensetzung des menschlichen,morphogenen knochenproteins mp52 - Google Patents

Gefriergetrocknete zusammensetzung des menschlichen,morphogenen knochenproteins mp52

Info

Publication number
ATE302021T1
ATE302021T1 AT98901044T AT98901044T ATE302021T1 AT E302021 T1 ATE302021 T1 AT E302021T1 AT 98901044 T AT98901044 T AT 98901044T AT 98901044 T AT98901044 T AT 98901044T AT E302021 T1 ATE302021 T1 AT E302021T1
Authority
AT
Austria
Prior art keywords
freeze
human
dried composition
bone protein
morphogenic bone
Prior art date
Application number
AT98901044T
Other languages
English (en)
Inventor
Mitsuko Inagaki
Hideki Ichikawa
Original Assignee
Bioph Biotech Entw Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioph Biotech Entw Pharm Gmbh filed Critical Bioph Biotech Entw Pharm Gmbh
Application granted granted Critical
Publication of ATE302021T1 publication Critical patent/ATE302021T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
AT98901044T 1997-01-30 1998-01-29 Gefriergetrocknete zusammensetzung des menschlichen,morphogenen knochenproteins mp52 ATE302021T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1634997 1997-01-30
PCT/JP1998/000371 WO1998033514A1 (fr) 1997-01-30 1998-01-29 Composition lyophilisee de mp52 humaine de proteines morphogenetiques osseuses

Publications (1)

Publication Number Publication Date
ATE302021T1 true ATE302021T1 (de) 2005-09-15

Family

ID=11913900

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98901044T ATE302021T1 (de) 1997-01-30 1998-01-29 Gefriergetrocknete zusammensetzung des menschlichen,morphogenen knochenproteins mp52

Country Status (22)

Country Link
EP (1) EP0972520B9 (de)
JP (1) JP4209948B2 (de)
KR (1) KR100548107B1 (de)
CN (1) CN1152712C (de)
AP (1) AP983A (de)
AT (1) ATE302021T1 (de)
AU (1) AU737595B2 (de)
BR (1) BR9807537B1 (de)
CA (1) CA2278546C (de)
DE (1) DE69831223T9 (de)
DK (1) DK0972520T3 (de)
EA (1) EA001579B1 (de)
ES (1) ES2244043T3 (de)
HU (1) HU226554B1 (de)
IL (2) IL130967A0 (de)
NO (1) NO322334B1 (de)
NZ (1) NZ336509A (de)
PL (1) PL189381B1 (de)
RS (1) RS49691B (de)
SI (1) SI0972520T1 (de)
TR (1) TR199901832T2 (de)
WO (1) WO1998033514A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2332564A1 (de) † 1997-02-07 2011-06-15 Stryker Corporation Matrixlose osteogene Vorrichtungen und Implantate und Verfahren zu deren Verwendung
WO2003030873A1 (en) * 2001-10-09 2003-04-17 Cellfactors Plc Therapeutic biological product and method for formation of new vascularised bone
AU2002308204B9 (en) 2001-11-19 2008-06-12 Scil Technology Gmbh Device having osteoinductive and osteoconductive properties
AU2003253049A1 (en) 2002-09-10 2004-04-30 Scil Technology Gmbh Metal implant coated under reduced oxygen concentration with osteoinductive protein
JP2007501223A (ja) * 2003-08-05 2007-01-25 フジ フォト フィルム ビー．ブイ． 安定剤としての組換え又は合成ゼラチンのワクチン中の使用
WO2005047323A1 (en) * 2003-11-10 2005-05-26 Arriva-Prometic Inc. Dry recombinant human alpha 1-antitrypsin formulation
ATE478008T1 (de) 2004-03-10 2010-09-15 Scil Technology Gmbh Überzogene implantate, ihre herstellung und verwendung davon
US20160344677A1 (en) 2015-05-22 2016-11-24 Microsoft Technology Licensing, Llc Unified messaging platform for providing interactive semantic objects
US10360287B2 (en) 2015-05-22 2019-07-23 Microsoft Technology Licensing, Llc Unified messaging platform and interface for providing user callouts

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0080879B1 (de) * 1981-11-28 1986-10-01 Sunstar Kabushiki Kaisha Stabilisiertes Interferon enthaltende pharmazeutische Zusammensetzung
US5037644A (en) * 1986-10-27 1991-08-06 Cetus Corporation Pharmaceutical compositions of recombinant interleukin-2 and formulation processes
DK0591392T3 (da) * 1991-06-21 1996-09-30 Genetics Inst Farmaceutiske formuleringer af osteogene proteiner
JP2966592B2 (ja) * 1991-07-20 1999-10-25 萩原 義秀 安定化されたヒトモノクローナル抗体製剤
KR0172186B1 (ko) * 1992-02-12 1999-02-01 미하엘 파울리스타 신규의 성장/분화인자를 암호화하는 dna 서열
CA2093836A1 (en) * 1992-04-24 1993-10-25 Wayne Gombotz Biodegradable tgf-.beta. delivery system for bone regeneration
DE4239877C1 (de) * 1992-11-27 1994-03-17 Boehringer Ingelheim Int Stabilisierte Superoxid-Dismutase (SOD)-Zusammensetzung
ATE209930T1 (de) * 1995-03-21 2001-12-15 Applied Research Systems Flüssige hcg-formulierungen
DK0955313T3 (da) * 1995-04-19 2006-08-21 Bioph Biotech Entw Pharm Gmbh Nyt protein og fremgangsmåde til fremstilling af samme

Also Published As

Publication number Publication date
JP4209948B2 (ja) 2009-01-14
DE69831223D1 (de) 2005-09-22
HUP0002386A3 (en) 2002-09-30
AP9901602A0 (en) 1999-09-30
CN1244127A (zh) 2000-02-09
NZ336509A (en) 2001-03-30
EA199900694A1 (ru) 2000-04-24
EP0972520A1 (de) 2000-01-19
EP0972520B9 (de) 2006-03-22
KR20000070586A (ko) 2000-11-25
EP0972520B1 (de) 2005-08-17
TR199901832T2 (xx) 1999-12-21
DE69831223T2 (de) 2006-02-16
CA2278546A1 (en) 1998-08-06
DK0972520T3 (da) 2005-12-19
WO1998033514A1 (fr) 1998-08-06
HUP0002386A2 (hu) 2000-11-28
NO993702D0 (no) 1999-07-29
CN1152712C (zh) 2004-06-09
SI0972520T1 (sl) 2006-02-28
EP0972520A4 (de) 2002-11-05
AU5679198A (en) 1998-08-25
AP983A (en) 2001-07-16
RS49691B (sr) 2007-12-31
HU226554B1 (en) 2009-03-30
NO322334B1 (no) 2006-09-18
YU34999A (sh) 2002-08-12
BR9807537B1 (pt) 2009-01-13
ES2244043T3 (es) 2005-12-01
IL130967A (en) 2006-12-10
PL334852A1 (en) 2000-03-27
NO993702L (no) 1999-09-29
IL130967A0 (en) 2001-01-28
CA2278546C (en) 2008-04-01
BR9807537A (pt) 2000-03-21
EA001579B1 (ru) 2001-06-25
KR100548107B1 (ko) 2006-02-02
DE69831223T9 (de) 2006-12-07
AU737595B2 (en) 2001-08-23
PL189381B1 (pl) 2005-07-29

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