AP783A - Composition of L-oddC Compound derivatives and methods of use as antineoplastic agents. - Google Patents

Composition of L-oddC Compound derivatives and methods of use as antineoplastic agents. Download PDF

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Publication number
AP783A
AP783A APAP/P/1997/000939A AP9700939A AP783A AP 783 A AP783 A AP 783A AP 9700939 A AP9700939 A AP 9700939A AP 783 A AP783 A AP 783A
Authority
AP
ARIPO
Prior art keywords
composition
tumor
cancer
pharmaceutically acceptable
compound
Prior art date
Application number
APAP/P/1997/000939A
Other languages
English (en)
Other versions
AP9700939A0 (en
Inventor
Chung K Chu
Young-Chi Cheng
Original Assignee
Univ Georgia
Univ Yale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/301,298 external-priority patent/US5817667A/en
Application filed by Univ Georgia, Univ Yale filed Critical Univ Georgia
Publication of AP9700939A0 publication Critical patent/AP9700939A0/xx
Application granted granted Critical
Publication of AP783A publication Critical patent/AP783A/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
APAP/P/1997/000939A 1994-09-06 1995-09-05 Composition of L-oddC Compound derivatives and methods of use as antineoplastic agents. AP783A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/301,298 US5817667A (en) 1991-04-17 1994-09-06 Compounds and methods for the treatment of cancer
US39063395A 1995-02-17 1995-02-17
PCT/US1995/011464 WO1996007413A1 (en) 1994-09-06 1995-09-05 Compounds and methods for the treatment of cancer

Publications (2)

Publication Number Publication Date
AP9700939A0 AP9700939A0 (en) 1997-04-30
AP783A true AP783A (en) 1999-11-17

Family

ID=26972285

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1997/000939A AP783A (en) 1994-09-06 1995-09-05 Composition of L-oddC Compound derivatives and methods of use as antineoplastic agents.

Country Status (31)

Country Link
US (3) US6063787A (is)
EP (2) EP1468687A1 (is)
JP (1) JP3979662B2 (is)
KR (1) KR100374477B1 (is)
CN (3) CN1111409C (is)
AP (1) AP783A (is)
AT (1) ATE267015T1 (is)
AU (1) AU704977B2 (is)
BG (1) BG63122B1 (is)
BR (1) BR9508886A (is)
CA (1) CA2199117C (is)
CZ (1) CZ297873B6 (is)
DE (1) DE69533066T2 (is)
DK (1) DK0781136T3 (is)
ES (1) ES2219666T3 (is)
FI (1) FI970918L (is)
HU (1) HUT77172A (is)
IL (1) IL115156A (is)
IS (1) IS2011B (is)
MY (1) MY121548A (is)
NO (1) NO313268B1 (is)
NZ (1) NZ335013A (is)
OA (1) OA10473A (is)
PL (2) PL188359B1 (is)
PT (1) PT781136E (is)
RO (1) RO118748B1 (is)
RU (1) RU2168995C2 (is)
SI (1) SI0781136T1 (is)
SK (1) SK284564B6 (is)
WO (1) WO1996007413A1 (is)
ZA (1) ZA957483B (is)

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CN101511375B (zh) * 2005-12-02 2012-09-05 耶鲁大学 L-胞嘧啶核苷类似物在制备用于治疗癌症和其它病症或疾病状态的药物中的应用
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KR20090057050A (ko) * 2006-09-01 2009-06-03 유니버시티 오브 조지아 리서치 파운데이션, 인코포레이티드 암치료를 위한 트록사시타빈 전구약물
RU2322243C1 (ru) * 2006-10-20 2008-04-20 Наталья Юрьевна Костюкова Фармацевтическая композиция для лечения поражений роговицы
CN103720693A (zh) * 2011-11-15 2014-04-16 张始状 人体五种正常碱基在制备治疗肿瘤药物中的应用
CN102406649A (zh) * 2011-11-15 2012-04-11 张始状 人体五种正常碱基在制备治疗肿瘤药物中的应用
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Also Published As

Publication number Publication date
FI970918A7 (fi) 1997-05-02
US8076347B2 (en) 2011-12-13
FI970918L (fi) 1997-05-02
IL115156A (en) 2000-07-16
PL188359B1 (pl) 2005-01-31
CA2199117A1 (en) 1996-03-14
FI970918A0 (fi) 1997-03-04
IS4434A (is) 1997-03-04
AU3586295A (en) 1996-03-27
SK28197A3 (en) 1997-09-10
CN1160351A (zh) 1997-09-24
NO971015D0 (no) 1997-03-05
EP0781136A4 (en) 1999-06-23
CN1448142A (zh) 2003-10-15
CN1251680C (zh) 2006-04-19
AP9700939A0 (en) 1997-04-30
CN1111409C (zh) 2003-06-18
BR9508886A (pt) 1997-12-30
JP3979662B2 (ja) 2007-09-19
DK0781136T3 (da) 2004-08-02
KR970705393A (ko) 1997-10-09
CN1827108A (zh) 2006-09-06
EP0781136A1 (en) 1997-07-02
NO313268B1 (no) 2002-09-09
US20080171758A1 (en) 2008-07-17
ES2219666T3 (es) 2004-12-01
DE69533066T2 (de) 2005-06-02
PT781136E (pt) 2004-09-30
NZ335013A (en) 2000-07-28
NO971015L (no) 1997-03-05
DE69533066D1 (de) 2004-06-24
CA2199117C (en) 2006-04-11
ATE267015T1 (de) 2004-06-15
PL318971A1 (en) 1997-07-21
WO1996007413A1 (en) 1996-03-14
EP0781136B1 (en) 2004-05-19
RO118748B1 (ro) 2003-10-30
JPH10506385A (ja) 1998-06-23
HUT77172A (hu) 1998-03-02
US7262213B2 (en) 2007-08-28
ZA957483B (en) 1997-06-06
AU704977B2 (en) 1999-05-13
IL115156A0 (en) 1995-12-31
SK284564B6 (sk) 2005-06-02
US6063787A (en) 2000-05-16
PL189288B1 (pl) 2005-07-29
MY121548A (en) 2006-02-28
SI0781136T1 (en) 2004-08-31
EP1468687A1 (en) 2004-10-20
OA10473A (en) 2002-04-08
BG63122B1 (bg) 2001-04-30
BG101284A (bg) 1998-03-31
CZ63397A3 (en) 1997-07-16
CZ297873B6 (cs) 2007-04-18
KR100374477B1 (ko) 2003-06-19
IS2011B (is) 2005-05-13
RU2168995C2 (ru) 2001-06-20
US20050261320A1 (en) 2005-11-24

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