AP718A - A controlled-release pharmaceutical formulation for oral administration. - Google Patents

A controlled-release pharmaceutical formulation for oral administration. Download PDF

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Publication number
AP718A
AP718A APAP/P/1996/000883A AP9600883A AP718A AP 718 A AP718 A AP 718A AP 9600883 A AP9600883 A AP 9600883A AP 718 A AP718 A AP 718A
Authority
AP
ARIPO
Prior art keywords
formulation
molecular weight
polyethylene oxide
range
hydroxypropylmethyl cellulose
Prior art date
Application number
APAP/P/1996/000883A
Other languages
English (en)
Other versions
AP9600883A0 (en
Inventor
Ross James Macrae
Janet Sarah Smith
Original Assignee
Pfizer Res & Development Company N V /S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Res & Development Company N V /S A filed Critical Pfizer Res & Development Company N V /S A
Publication of AP9600883A0 publication Critical patent/AP9600883A0/xx
Application granted granted Critical
Publication of AP718A publication Critical patent/AP718A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
APAP/P/1996/000883A 1995-11-21 1996-11-21 A controlled-release pharmaceutical formulation for oral administration. AP718A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9523752.5A GB9523752D0 (en) 1995-11-21 1995-11-21 Pharmaceutical formulations

Publications (2)

Publication Number Publication Date
AP9600883A0 AP9600883A0 (en) 1997-01-31
AP718A true AP718A (en) 1999-01-06

Family

ID=10784188

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1996/000883A AP718A (en) 1995-11-21 1996-11-21 A controlled-release pharmaceutical formulation for oral administration.

Country Status (29)

Country Link
EP (1) EP0862437A1 (es)
JP (1) JPH10513481A (es)
KR (1) KR19990071505A (es)
CN (1) CN1215993A (es)
AP (1) AP718A (es)
AR (1) AR004335A1 (es)
AU (1) AU709560B2 (es)
BG (1) BG102438A (es)
BR (1) BR9611626A (es)
CA (1) CA2232715A1 (es)
CO (1) CO4480020A1 (es)
CZ (1) CZ155498A3 (es)
GB (1) GB9523752D0 (es)
HR (1) HRP960554A2 (es)
HU (1) HUP9903734A3 (es)
IS (1) IS4706A (es)
MA (1) MA26410A1 (es)
MX (1) MX9804008A (es)
NO (1) NO982302L (es)
NZ (1) NZ322053A (es)
OA (1) OA10687A (es)
PE (1) PE22898A1 (es)
PL (1) PL326981A1 (es)
SK (1) SK63098A3 (es)
TN (1) TNSN96141A1 (es)
TR (1) TR199800902T2 (es)
WO (1) WO1997018814A1 (es)
YU (1) YU62096A (es)
ZA (1) ZA969722B (es)

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GT199900061A (es) * 1998-05-15 2000-10-14 Pfizer Formulaciones farmaceuticas.
EP0987020A1 (en) * 1998-09-04 2000-03-22 Pharma Pass LLC Metoprolol composition and processes for manufacturing the same
EP0974343B1 (en) * 1998-07-22 2004-09-29 Pharma Pass II LLC Process for manufacturing a solid metoprolol composition
CO5140079A1 (es) * 1998-10-14 2002-03-22 Novartis Ag Composicion farmaceutica de liberacion sostenida y metodo para liberar un agente farmaceuticamente activo de liberacion sostenida y metodo para liberar un agente far- maceuticamente activo
UA67802C2 (uk) 1998-10-23 2004-07-15 Пфайзер Рісьоч Енд Дівелепмент Компані, Н.В./С.А. Фармацевтична композиція з контрольованим вивільненням інгібітора цгмф фде-5 (варіанти), спосіб її одержання та спосіб лікування еректильної дисфункції
US20030059467A1 (en) * 2001-09-14 2003-03-27 Pawan Seth Pharmaceutical composition comprising doxasozin
US6723340B2 (en) 2001-10-25 2004-04-20 Depomed, Inc. Optimal polymer mixtures for gastric retentive tablets
US7612112B2 (en) 2001-10-25 2009-11-03 Depomed, Inc. Methods of treatment using a gastric retained gabapentin dosage
TWI312285B (en) 2001-10-25 2009-07-21 Depomed Inc Methods of treatment using a gastric retained gabapentin dosage
US8329217B2 (en) 2001-11-06 2012-12-11 Osmotica Kereskedelmi Es Szolgaltato Kft Dual controlled release dosage form
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
EP1680078A2 (en) * 2003-10-17 2006-07-19 Ranbaxy Laboratories, Ltd. Oral matrix formulations of doxazosin
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KR100574554B1 (ko) * 2004-05-28 2006-04-27 한미약품 주식회사 니아신의 경구투여용 서방성 조성물
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
KR100679111B1 (ko) * 2004-11-20 2007-02-07 대우약품공업주식회사 독사조신을 포함하는 서방성 정제
MX2008002492A (es) * 2005-08-22 2008-04-03 Novartis Ag Composiciones farmaceuticas que comprenden un farmaco dependiente del ph, un modificador del ph, y un agente retardante.
US20090176882A1 (en) 2008-12-09 2009-07-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
WO2007127630A1 (en) 2006-04-26 2007-11-08 Supernus Pharmaceuticals, Inc Controlled released preparations of oxcarbazepine having sigmoidal release profile
BRPI0711558A2 (pt) 2006-05-04 2011-11-08 Boeringer Ingelheim Internat Gmbh polimorfos
PE20110235A1 (es) 2006-05-04 2011-04-14 Boehringer Ingelheim Int Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
CN100396282C (zh) * 2006-07-25 2008-06-25 山东省医药工业研究所 甲磺酸多沙唑嗪缓释胶囊及制备方法
SA07280459B1 (ar) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
CN102105136B (zh) 2008-03-11 2014-11-26 蒂宝制药公司 包含非-阿片类止痛剂和阿片类止痛剂的组合的胃滞留型缓释剂型
US8372432B2 (en) 2008-03-11 2013-02-12 Depomed, Inc. Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic
PE20091730A1 (es) 2008-04-03 2009-12-10 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
KR20190016601A (ko) 2008-08-06 2019-02-18 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
KR101004205B1 (ko) * 2008-12-17 2010-12-24 동아제약주식회사 유데나필 함유 서방성 제제를 제조하기 위한 제어방출 조성물
AP2011005794A0 (en) 2009-02-13 2011-08-31 Boehringer Ingelheim Int Pharmaceutical composition comprising a SGLT2 inhibitor, a DPP-IV inhibitor and optionally a furtherantidiabetic agent and uses thereof.
US9901551B2 (en) 2009-04-20 2018-02-27 Ambra Bioscience Llc Chemosensory receptor ligand-based therapies
US8828953B2 (en) 2009-04-20 2014-09-09 NaZura BioHealth, Inc. Chemosensory receptor ligand-based therapies
EA201101524A1 (ru) 2009-04-20 2012-07-30 Элселикс Терапьютикс, Инк. Способ и композиция для лечения состояния, связанного с хемосенсорным рецептором
MX364651B (es) 2009-11-27 2019-05-03 Boehringer Ingelheim Int Gmbh Star Inhibidores de dpp-iv, tales como la linagliptina, y composiciones farmacéuticas o combinaciones que comprenden los mismos, para usarse en el tratamiento de pacientes diabéticos tipificados genéticamente.
US20110150989A1 (en) * 2009-12-22 2011-06-23 Mallinkckrodt Inc. Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans
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Citations (3)

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Publication number Priority date Publication date Assignee Title
GB2123291A (en) * 1982-07-06 1984-02-01 Lepetit Spa Suloctidil compositions
US4837111A (en) * 1988-03-21 1989-06-06 Alza Corporation Dosage form for dispensing drug for human therapy
WO1992001445A1 (en) * 1990-07-23 1992-02-06 Alza Corporation Oral osmotic device for delivering nicotine

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US4765989A (en) * 1983-05-11 1988-08-23 Alza Corporation Osmotic device for administering certain drugs
IL92966A (en) * 1989-01-12 1995-07-31 Pfizer Hydrogel-operated release devices

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
GB2123291A (en) * 1982-07-06 1984-02-01 Lepetit Spa Suloctidil compositions
US4837111A (en) * 1988-03-21 1989-06-06 Alza Corporation Dosage form for dispensing drug for human therapy
WO1992001445A1 (en) * 1990-07-23 1992-02-06 Alza Corporation Oral osmotic device for delivering nicotine

Also Published As

Publication number Publication date
BG102438A (en) 1999-01-29
GB9523752D0 (en) 1996-01-24
NO982302D0 (no) 1998-05-20
PE22898A1 (es) 1998-05-07
CN1215993A (zh) 1999-05-05
HUP9903734A3 (en) 2000-04-28
TNSN96141A1 (fr) 2005-03-15
MA26410A1 (fr) 2004-12-20
PL326981A1 (en) 1998-11-09
ZA969722B (en) 1998-05-20
TR199800902T2 (xx) 1998-09-21
NO982302L (no) 1998-07-17
AP9600883A0 (en) 1997-01-31
EP0862437A1 (en) 1998-09-09
HUP9903734A2 (hu) 2000-03-28
HRP960554A2 (en) 1998-02-28
BR9611626A (pt) 1999-06-01
KR19990071505A (ko) 1999-09-27
MX9804008A (es) 1998-09-30
AU7572196A (en) 1997-06-11
NZ322053A (en) 1999-11-29
JPH10513481A (ja) 1998-12-22
WO1997018814A1 (en) 1997-05-29
CZ155498A3 (cs) 1999-03-17
SK63098A3 (en) 1999-05-07
IS4706A (is) 1998-03-31
OA10687A (en) 2002-11-27
CO4480020A1 (es) 1997-07-09
AU709560B2 (en) 1999-09-02
AR004335A1 (es) 1998-11-04
CA2232715A1 (en) 1997-05-29
YU62096A (sh) 1999-03-04

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