AP3000A - Slow release pharmaceutical composition made of microparticles - Google Patents

Slow release pharmaceutical composition made of microparticles

Info

Publication number
AP3000A
AP3000A AP2009005088A AP2009005088A AP3000A AP 3000 A AP3000 A AP 3000A AP 2009005088 A AP2009005088 A AP 2009005088A AP 2009005088 A AP2009005088 A AP 2009005088A AP 3000 A AP3000 A AP 3000A
Authority
AP
ARIPO
Prior art keywords
microparticles
pharmaceutical composition
slow release
release pharmaceutical
composition made
Prior art date
Application number
AP2009005088A
Other languages
English (en)
Other versions
AP2009005088A0 (en
Inventor
Bertrand Ducrey
Patrick Garrouste
Catherine Curdy
Original Assignee
Debiopharm Res & Mfg Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40032512&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP3000(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Debiopharm Res & Mfg Sa filed Critical Debiopharm Res & Mfg Sa
Publication of AP2009005088A0 publication Critical patent/AP2009005088A0/en
Application granted granted Critical
Publication of AP3000A publication Critical patent/AP3000A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AP2009005088A 2007-06-06 2008-06-06 Slow release pharmaceutical composition made of microparticles AP3000A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07109767 2007-06-06
IB2007054372 2007-10-27

Publications (2)

Publication Number Publication Date
AP2009005088A0 AP2009005088A0 (en) 2009-12-31
AP3000A true AP3000A (en) 2014-10-31

Family

ID=40032512

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2009005088A AP3000A (en) 2007-06-06 2008-06-06 Slow release pharmaceutical composition made of microparticles

Country Status (32)

Country Link
US (4) US10166181B2 (me)
EP (3) EP3431077A1 (me)
JP (1) JP5419169B2 (me)
KR (1) KR101631475B1 (me)
CN (1) CN101677959B (me)
AP (1) AP3000A (me)
AU (1) AU2008259411B2 (me)
BR (1) BRPI0812250B8 (me)
CA (1) CA2688478C (me)
CO (1) CO6251234A2 (me)
CY (2) CY1118434T1 (me)
DK (2) DK2164467T3 (me)
EA (1) EA019284B1 (me)
ES (2) ES2611020T3 (me)
FI (1) FI2500014T4 (me)
HR (2) HRP20181854T4 (me)
HU (2) HUE031550T2 (me)
IL (1) IL202501A (me)
LT (2) LT2164467T (me)
MA (1) MA31422B1 (me)
ME (1) ME00959B (me)
MX (1) MX2009012856A (me)
MY (1) MY150450A (me)
NZ (1) NZ582423A (me)
PL (2) PL2164467T3 (me)
PT (2) PT2500014T (me)
RS (2) RS55591B1 (me)
SI (2) SI2164467T1 (me)
TN (1) TN2009000476A1 (me)
UA (1) UA99830C2 (me)
WO (1) WO2008149320A2 (me)
ZA (1) ZA200907940B (me)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE031550T2 (en) 2007-06-06 2017-07-28 Debiopharm Res & Mfg Sa Slow release pharmaceutical composition made of microparticles
PT105270B (pt) 2010-08-26 2012-05-31 Domino Ind Ceramicas S A Camada de sílica com libertação lenta de fragrância, telha cerâmica e respectivo processo de produção
CN105267153B (zh) * 2015-11-27 2018-05-11 上海苏豪逸明制药有限公司 一种曲普瑞林缓释微粒及其制备方法
CN105797134B (zh) * 2016-03-29 2019-06-14 浙江圣兆药物科技股份有限公司 一种难溶亮丙瑞林缓释制剂
WO2018083633A1 (en) 2016-11-02 2018-05-11 Debiopharm International, S.A. Methods for improving anti-cd37 immunoconjugate therapy
KR102402639B1 (ko) 2017-11-24 2022-05-26 삼성전자주식회사 전자 장치 및 그의 통신 방법
CN111000798B (zh) * 2019-12-26 2021-11-23 四川恒博生物科技有限公司 一种采用原位凝胶技术的犬用非手术去势注射液
IT202000017191A1 (it) 2020-07-15 2022-01-15 Xbrane Biopharma Ab Procedimento senza acqua per preparare una composizione farmaceutica per un rilascio più prolungato e controllato di triptorelina o di un suo sale
KR102464821B1 (ko) * 2022-04-13 2022-11-09 (주)인벤티지랩 목시덱틴을 포함하는 마이크로 입자 및 이를 포함하는 서방형 주사제 조성물
AR133300A1 (es) 2023-07-20 2025-09-17 Ferring Bv Micropartículas cargadas con fármaco de liberación prolongada
WO2025099253A1 (en) * 2023-11-08 2025-05-15 Debiopharm International Sa Novel composition
CN121401211A (zh) * 2024-02-29 2026-01-27 珠海市华海康医药科技有限责任公司 一种双羟萘酸盐药物缓释微球及其制备方法
CN121818889A (zh) 2024-10-08 2026-04-10 费灵有限公司 曲普瑞林组合物及其用途

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5134122A (en) * 1989-07-28 1992-07-28 Debiopharm S.A. Method for preparing a pharmaceutical composition in the form of microparticles
GB2257909A (en) * 1991-07-22 1993-01-27 Debio Rech Pharma Sa Preparation of controlled release peptide compositions
US5192741A (en) * 1987-09-21 1993-03-09 Debiopharm S.A. Sustained and controlled release of water insoluble polypeptides
US5225205A (en) * 1989-07-28 1993-07-06 Debiopharm S.A. Pharmaceutical composition in the form of microparticles
US5540937A (en) * 1992-07-27 1996-07-30 Rhone Merieux Process for preparing microspheres for the prolonged release of the LHRH hormone and its analogues, microspheres and formulations obtained
US20020013273A1 (en) * 1997-11-07 2002-01-31 Bret Shirley Method for producing sustained-release formulations
US20040170665A1 (en) * 2000-06-02 2004-09-02 Allergan, Inc. Intravitreal botulinum toxin implant
WO2004096259A1 (en) * 2003-04-30 2004-11-11 Debiopharm S.A. Methods and compositions using gonadotropin hormone releasing hormone

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0190833B1 (en) 1985-02-07 1991-03-27 Takeda Chemical Industries, Ltd. Method for producing microcapsule
US4897268A (en) * 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
MY107937A (en) 1990-02-13 1996-06-29 Takeda Chemical Industries Ltd Prolonged release microcapsules.
JP3277342B2 (ja) 1992-09-02 2002-04-22 武田薬品工業株式会社 徐放性マイクロカプセルの製造法
JPH09504523A (ja) * 1993-10-22 1997-05-06 ジェネンテク，インコーポレイテッド アジュバントのマイクロカプセル化方法および組成物
US5945128A (en) * 1996-09-04 1999-08-31 Romano Deghenghi Process to manufacture implants containing bioactive peptides
AR012448A1 (es) * 1997-04-18 2000-10-18 Ipsen Pharma Biotech Composicion en forma de microcapsulas o de implantes que comprende un excipiente biodegradable, polimero o co-polimero, o una mezcla de talesexcipientes, y una sustancia activa o una mezcla de sustancias activas, procedimiento para la preparacion de una sustancia soluble en agua de elevada
TW200800298A (en) * 2000-01-27 2008-01-01 Zentaris Ag Compressed microparticles for dry injection
EP1450766B1 (fr) * 2001-10-10 2015-04-22 Pierre Fabre Medicament Microspheres biodegradables a liberation prolongee et leur procede de preparation
KR100466637B1 (ko) * 2003-06-26 2005-01-13 주식회사 펩트론 서방성 미립구의 혼합 제형을 연속한 단일 공정으로제조하는 방법
FR2865938B1 (fr) * 2004-02-05 2006-06-02 Sod Conseils Rech Applic Formulation retard solide comprenant de l'acetate de triptoreline
RU2464972C2 (ru) † 2005-12-22 2012-10-27 Новартис Аг Композиции с замедленным высвобождением, включающие октреотид и два или более сополимера полилактида и гликолида
HUE031550T2 (en) 2007-06-06 2017-07-28 Debiopharm Res & Mfg Sa Slow release pharmaceutical composition made of microparticles

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192741A (en) * 1987-09-21 1993-03-09 Debiopharm S.A. Sustained and controlled release of water insoluble polypeptides
US5134122A (en) * 1989-07-28 1992-07-28 Debiopharm S.A. Method for preparing a pharmaceutical composition in the form of microparticles
US5225205A (en) * 1989-07-28 1993-07-06 Debiopharm S.A. Pharmaceutical composition in the form of microparticles
GB2257909A (en) * 1991-07-22 1993-01-27 Debio Rech Pharma Sa Preparation of controlled release peptide compositions
US5540937A (en) * 1992-07-27 1996-07-30 Rhone Merieux Process for preparing microspheres for the prolonged release of the LHRH hormone and its analogues, microspheres and formulations obtained
US20020013273A1 (en) * 1997-11-07 2002-01-31 Bret Shirley Method for producing sustained-release formulations
US20040170665A1 (en) * 2000-06-02 2004-09-02 Allergan, Inc. Intravitreal botulinum toxin implant
WO2004096259A1 (en) * 2003-04-30 2004-11-11 Debiopharm S.A. Methods and compositions using gonadotropin hormone releasing hormone

Also Published As

Publication number Publication date
HUE040391T2 (hu) 2019-03-28
RS58248B1 (sr) 2019-03-29
IL202501A0 (en) 2010-06-30
JP2010529106A (ja) 2010-08-26
HRP20161785T1 (hr) 2017-03-10
ZA200907940B (en) 2010-08-25
BRPI0812250B8 (pt) 2021-05-25
ME00959B (me) 2012-06-20
ES2694401T3 (es) 2018-12-20
EP2500014B1 (en) 2018-08-08
CY1118434T1 (el) 2017-06-28
LT2164467T (lt) 2017-01-25
WO2008149320A3 (en) 2009-02-05
MY150450A (en) 2014-01-30
PT2500014T (pt) 2018-11-21
KR101631475B1 (ko) 2016-06-20
SI2500014T1 (sl) 2019-02-28
EP2500014A3 (en) 2012-11-07
JP5419169B2 (ja) 2014-02-19
US20110052717A1 (en) 2011-03-03
BRPI0812250A2 (pt) 2014-12-23
CO6251234A2 (es) 2011-02-21
NZ582423A (en) 2011-10-28
LT2500014T (lt) 2019-01-25
CA2688478C (en) 2015-10-27
SI2500014T2 (sl) 2025-05-30
CN101677959B (zh) 2014-02-26
RS55591B1 (sr) 2017-06-30
EP2500014A2 (en) 2012-09-19
TN2009000476A1 (en) 2011-03-31
US20190192423A1 (en) 2019-06-27
EA200971132A1 (ru) 2010-04-30
MX2009012856A (es) 2009-12-15
HK1141737A1 (en) 2010-11-19
PL2164467T3 (pl) 2017-07-31
HUE031550T2 (en) 2017-07-28
HRP20181854T4 (hr) 2025-05-09
DK2164467T3 (en) 2017-01-30
BRPI0812250B1 (pt) 2020-03-03
PL2500014T3 (pl) 2019-04-30
ES2611020T3 (es) 2017-05-04
PT2164467T (pt) 2017-01-13
PL2500014T5 (pl) 2025-05-05
ES2694401T5 (es) 2025-05-16
DK2500014T4 (da) 2025-04-14
AU2008259411A1 (en) 2008-12-11
EA019284B1 (ru) 2014-02-28
EP2164467B1 (en) 2016-12-14
FI2500014T4 (fi) 2025-04-08
EP2164467A2 (en) 2010-03-24
US10166181B2 (en) 2019-01-01
KR20100023950A (ko) 2010-03-04
SI2164467T1 (sl) 2017-05-31
CN101677959A (zh) 2010-03-24
CA2688478A1 (en) 2008-12-11
AU2008259411B2 (en) 2013-10-17
DK2500014T3 (en) 2018-12-03
IL202501A (en) 2015-11-30
UA99830C2 (uk) 2012-10-10
CY1120891T1 (el) 2019-12-11
US20230082575A1 (en) 2023-03-16
EP3431077A1 (en) 2019-01-23
EP2500014B2 (en) 2025-02-19
WO2008149320A2 (en) 2008-12-11
HRP20181854T1 (hr) 2019-02-08
AP2009005088A0 (en) 2009-12-31
MA31422B1 (fr) 2010-06-01
US20250205148A1 (en) 2025-06-26

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