AP282A - Novel derivatives of (p. substituted phenyl) oxybutane amines, their processes of production and the pharmaceutical compositions containing them. - Google Patents

Novel derivatives of (p. substituted phenyl) oxybutane amines, their processes of production and the pharmaceutical compositions containing them. Download PDF

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Publication number
AP282A
AP282A APAP/P/1991/000328A AP9100328A AP282A AP 282 A AP282 A AP 282A AP 9100328 A AP9100328 A AP 9100328A AP 282 A AP282 A AP 282A
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AP
ARIPO
Prior art keywords
formula
compound
group
derivative
hal
Prior art date
Application number
APAP/P/1991/000328A
Other languages
English (en)
Other versions
AP9100328A0 (en
Inventor
Paule Bonnet
Remi Delansorne
Maurice Faure
Michel Lanquetin
Serge Zunino
Original Assignee
Laboratoire Theramex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Theramex filed Critical Laboratoire Theramex
Publication of AP9100328A0 publication Critical patent/AP9100328A0/xx
Application granted granted Critical
Publication of AP282A publication Critical patent/AP282A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
APAP/P/1991/000328A 1990-10-17 1991-10-17 Novel derivatives of (p. substituted phenyl) oxybutane amines, their processes of production and the pharmaceutical compositions containing them. AP282A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR909012562A FR2668150B1 (fr) 1990-10-17 1990-10-17 Nouveaux derives du terbutylphenyl 1-amino 4-hydroxybutane, leurs procedes de preparation et les compositions pharmaceutiques en renfermant.

Publications (2)

Publication Number Publication Date
AP9100328A0 AP9100328A0 (en) 1991-10-31
AP282A true AP282A (en) 1993-09-08

Family

ID=9401134

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1991/000328A AP282A (en) 1990-10-17 1991-10-17 Novel derivatives of (p. substituted phenyl) oxybutane amines, their processes of production and the pharmaceutical compositions containing them.

Country Status (23)

Country Link
US (1) US5461059A (ko)
EP (1) EP0505543A1 (ko)
JP (1) JPH05503298A (ko)
KR (1) KR927003589A (ko)
AP (1) AP282A (ko)
BG (1) BG60680B1 (ko)
BR (1) BR9106188A (ko)
CA (1) CA2071911A1 (ko)
CZ (1) CZ182292A3 (ko)
FI (1) FI922773A (ko)
FR (2) FR2668150B1 (ko)
HU (1) HUT61297A (ko)
IE (1) IE913636A1 (ko)
IL (1) IL99776A0 (ko)
MA (1) MA22321A1 (ko)
NO (1) NO922358L (ko)
NZ (1) NZ240274A (ko)
OA (1) OA09835A (ko)
PL (2) PL169452B1 (ko)
PT (1) PT99266A (ko)
RO (1) RO108241B1 (ko)
WO (1) WO1992006977A1 (ko)
ZA (1) ZA918282B (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2048109B1 (es) * 1992-07-20 1994-12-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol.
US5624948A (en) * 1993-05-20 1997-04-29 Kissei Pharmaceutical Co., Ltd. 1-(2-benzimidazolyl)-1,5-diazacyclooctane compounds
ES2072193B1 (es) * 1993-05-21 1996-02-16 Espanola Prod Quimicos Nuevos derivados del1-fenilmetil bencimidazol piperacinas.
US5691323A (en) * 1995-05-12 1997-11-25 Merck & Co., Inc. Muscarine antagonists
FR2727865B1 (fr) * 1994-12-08 1997-07-18 Esteve Labor Dr Utilisation des derives de 2-(4-(azolybutyl)-piperazinyl- (methyl))-benzimidazole et analogues ainsi que de leurs sels, pour la preparation de medicaments destines au traitement ou a la prophylaxie de l'asthme
AU707139B2 (en) * 1996-04-03 1999-07-01 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
JP2004502690A (ja) * 2000-07-04 2004-01-29 ノボ　ノルディスク　アクティーゼルスカブ 酵素ｄｐｐ−ｉｖのインヒビターである複素環式化合物
US7495004B2 (en) * 2002-06-17 2009-02-24 Glaxo Group Limited Purine derivatives as liver X receptor agonists

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695575A (en) * 1984-11-13 1987-09-22 Janssen Pharmaceutica, N.V. 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines
EP0282133A2 (en) * 1987-03-09 1988-09-14 Janssen Pharmaceutica N.V. 1-alkyl substituted benzimidazole derivatives
US4908372A (en) * 1988-10-13 1990-03-13 Merrell Dow Pharmaceuticals Inc. Antihistaminic piperidinyl benzimidazoles
EP0393738A1 (en) * 1989-04-07 1990-10-24 Janssen Pharmaceutica N.V. Hydroxyalkylfuranyl derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL130095C (ko) * 1962-08-31
US3161645A (en) * 1962-12-18 1964-12-15 Res Lab Dr C Janssen N V 1-(1-aroylpropyl-4-piperidyl)-2-benzimidazolinones and related compounds
US3491103A (en) * 1963-12-19 1970-01-20 Sandoz Ag Certain 4h-benzo(4,5)cyclohepta-(1,2-b) thiophenes
US4219559A (en) * 1979-01-10 1980-08-26 Janssen Pharmaceutica N.V. N-Heterocyclyl-4-piperidinamines
JPS5879983A (ja) * 1981-11-06 1983-05-13 Kanebo Ltd 新規なベンズイミダゾ−ル誘導体、その製造法およびその医薬組成物
CA1341370C (en) * 1988-04-28 2002-06-18 John J. Powinski Fused polycyclic compounds, methods of manufacture, and their use as paf antagonists, antihistamines and/or antiinflammatory agents
US5217980A (en) * 1990-07-19 1993-06-08 Janssen Pharmaceutica N.V. Oxazolyl and piperidinyl substituted benimidazolyl compounds

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695575A (en) * 1984-11-13 1987-09-22 Janssen Pharmaceutica, N.V. 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines
EP0282133A2 (en) * 1987-03-09 1988-09-14 Janssen Pharmaceutica N.V. 1-alkyl substituted benzimidazole derivatives
US4908372A (en) * 1988-10-13 1990-03-13 Merrell Dow Pharmaceuticals Inc. Antihistaminic piperidinyl benzimidazoles
EP0393738A1 (en) * 1989-04-07 1990-10-24 Janssen Pharmaceutica N.V. Hydroxyalkylfuranyl derivatives

Also Published As

Publication number Publication date
FR2668150B1 (fr) 1994-11-18
OA09835A (fr) 1994-08-15
US5461059A (en) 1995-10-24
MA22321A1 (fr) 1992-07-01
WO1992006977A1 (fr) 1992-04-30
HU9202176D0 (en) 1992-10-28
FI922773A0 (fi) 1992-06-16
HUT61297A (en) 1992-12-28
NO922358D0 (no) 1992-06-16
JPH05503298A (ja) 1993-06-03
KR927003589A (ko) 1992-12-18
CA2071911A1 (fr) 1992-04-18
BG96487A (bg) 1993-12-24
PL169452B1 (pl) 1996-07-31
IL99776A0 (en) 1992-08-18
EP0505543A1 (fr) 1992-09-30
CZ182292A3 (en) 1993-01-13
AP9100328A0 (en) 1991-10-31
BG60680B1 (bg) 1995-12-29
NZ240274A (en) 1995-07-26
PL169022B1 (pl) 1996-05-31
FR2670783A1 (fr) 1992-06-26
FR2668150A1 (fr) 1992-04-24
BR9106188A (pt) 1993-03-16
RO108241B1 (ro) 1994-03-31
NO922358L (no) 1992-08-11
ZA918282B (en) 1992-07-29
PT99266A (pt) 1992-08-31
FR2670783B1 (fr) 1994-11-18
IE913636A1 (en) 1992-04-22
FI922773A (fi) 1992-06-16

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