AP224A - Azabenzimidazoles in the treatment of asthma, arthritis and related diseases. - Google Patents

Azabenzimidazoles in the treatment of asthma, arthritis and related diseases. Download PDF

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Publication number
AP224A
AP224A APAP/P/1991/000259A AP9100259A AP224A AP 224 A AP224 A AP 224A AP 9100259 A AP9100259 A AP 9100259A AP 224 A AP224 A AP 224A
Authority
AP
ARIPO
Prior art keywords
compound
bad original
het
product
fluoro
Prior art date
Application number
APAP/P/1991/000259A
Other languages
English (en)
Other versions
AP9100259A0 (en
Inventor
Anthony Mafrat
James Fredrick Eggler
Kevin Cooper
Michael Jonathan Fray
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of AP9100259A0 publication Critical patent/AP9100259A0/xx
Application granted granted Critical
Publication of AP224A publication Critical patent/AP224A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
APAP/P/1991/000259A 1990-05-09 1991-05-08 Azabenzimidazoles in the treatment of asthma, arthritis and related diseases. AP224A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52119990A 1990-05-09 1990-05-09

Publications (2)

Publication Number Publication Date
AP9100259A0 AP9100259A0 (en) 1991-07-31
AP224A true AP224A (en) 1992-10-27

Family

ID=24075786

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1991/000259A AP224A (en) 1990-05-09 1991-05-08 Azabenzimidazoles in the treatment of asthma, arthritis and related diseases.

Country Status (28)

Country Link
EP (1) EP0533695B1 (fr)
JP (1) JPH0678340B2 (fr)
CN (1) CN1057839A (fr)
AP (1) AP224A (fr)
AT (1) ATE112567T1 (fr)
AU (1) AU642265B2 (fr)
BG (1) BG97059A (fr)
BR (1) BR9106433A (fr)
CA (1) CA2080476A1 (fr)
DE (1) DE69104481T2 (fr)
DK (1) DK0533695T3 (fr)
ES (1) ES2061247T3 (fr)
FI (1) FI925053A (fr)
GT (1) GT199100031A (fr)
HU (1) HUT62894A (fr)
IE (1) IE911553A1 (fr)
IL (1) IL98075A0 (fr)
MA (1) MA22151A1 (fr)
MY (1) MY105512A (fr)
NO (1) NO924290D0 (fr)
NZ (1) NZ238089A (fr)
PE (1) PE26691A1 (fr)
PT (1) PT97616A (fr)
RO (1) RO109450B1 (fr)
TW (1) TW205549B (fr)
WO (1) WO1991017163A1 (fr)
YU (1) YU81191A (fr)
ZA (1) ZA913497B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9102997D0 (en) * 1991-02-13 1991-03-27 Pfizer Ltd Therapeutic agents
WO1994004537A2 (fr) * 1992-08-20 1994-03-03 Cytomed, Inc. Agents a double fonctionnalite anti-inflammatoire et d'immunosuppression
US6372770B1 (en) 1994-10-12 2002-04-16 Euro-Celtique, S.A. Benzoxazoles
US6232322B1 (en) 1998-05-12 2001-05-15 American Home Products Corporation Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
DE69904318D1 (de) * 1998-05-12 2003-01-16 Wyeth Corp Zur behandlung von insulin-resistenz und hyperglycemie geeignete biphenyl-oxo-essigsäuren
US6310081B1 (en) 1999-05-10 2001-10-30 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
GB0302094D0 (en) 2003-01-29 2003-02-26 Pharmagene Lab Ltd EP4 receptor antagonists
GB0324269D0 (en) 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
EP3044210A4 (fr) * 2013-09-13 2017-03-15 Cortendo AB (publ) Nouveaux inhibiteurs du cytochrome p450 et leur méthode d'utilisation
CN105348182B (zh) * 2014-08-24 2018-04-13 复旦大学 2‑烷氧基苯甲酰芳胺类化合物及其药物用途

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2113675A (en) * 1981-11-10 1983-08-10 Wellcome Found Imidazo (4,5-c) pyridine derivatives
US4963560A (en) * 1988-09-21 1990-10-16 Pfizer Inc. 1,4-dihydropyridine derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8804439D0 (en) * 1988-02-25 1988-03-23 Pfizer Ltd Dihydropyridines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2113675A (en) * 1981-11-10 1983-08-10 Wellcome Found Imidazo (4,5-c) pyridine derivatives
US4963560A (en) * 1988-09-21 1990-10-16 Pfizer Inc. 1,4-dihydropyridine derivatives

Also Published As

Publication number Publication date
HU9203496D0 (en) 1993-01-28
ES2061247T3 (es) 1994-12-01
IL98075A0 (en) 1992-06-21
IE911553A1 (en) 1991-11-20
WO1991017163A1 (fr) 1991-11-14
ZA913497B (en) 1992-12-30
EP0533695B1 (fr) 1994-10-05
BR9106433A (pt) 1993-05-04
PE26691A1 (es) 1991-10-21
FI925053A0 (fi) 1992-11-06
JPH0678340B2 (ja) 1994-10-05
NZ238089A (en) 1992-10-28
DE69104481D1 (de) 1994-11-10
HUT62894A (en) 1993-06-28
BG97059A (bg) 1993-12-24
AU7867191A (en) 1991-11-27
TW205549B (fr) 1993-05-11
CN1057839A (zh) 1992-01-15
NO924290L (no) 1992-11-06
AP9100259A0 (en) 1991-07-31
YU81191A (sh) 1994-06-10
CA2080476A1 (fr) 1991-11-10
FI925053A (fi) 1992-11-06
PT97616A (pt) 1992-03-31
GT199100031A (es) 1992-10-30
MY105512A (en) 1994-10-31
EP0533695A1 (fr) 1993-03-31
AU642265B2 (en) 1993-10-14
MA22151A1 (fr) 1991-12-31
NO924290D0 (no) 1992-11-06
DK0533695T3 (da) 1995-01-09
ATE112567T1 (de) 1994-10-15
RO109450B1 (ro) 1995-02-28
DE69104481T2 (de) 1995-02-09
JPH05505619A (ja) 1993-08-19

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