AP2015008732A0 - Human pac1 antibodies - Google Patents

Human pac1 antibodies

Info

Publication number
AP2015008732A0
AP2015008732A0 AP2015008732A AP2015008732A AP2015008732A0 AP 2015008732 A0 AP2015008732 A0 AP 2015008732A0 AP 2015008732 A AP2015008732 A AP 2015008732A AP 2015008732 A AP2015008732 A AP 2015008732A AP 2015008732 A0 AP2015008732 A0 AP 2015008732A0
Authority
AP
ARIPO
Prior art keywords
human pac1
pac1 antibodies
antibodies
human
pac1
Prior art date
Application number
AP2015008732A
Other languages
English (en)
Inventor
Agnes Eva Hamburger
Cen Xu
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of AP2015008732A0 publication Critical patent/AP2015008732A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
AP2015008732A 2013-03-15 2014-03-14 Human pac1 antibodies AP2015008732A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361792678P 2013-03-15 2013-03-15
PCT/US2014/029128 WO2014144632A2 (en) 2013-03-15 2014-03-14 Human pac1 antibodies

Publications (1)

Publication Number Publication Date
AP2015008732A0 true AP2015008732A0 (en) 2015-09-30

Family

ID=50439531

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2015008732A AP2015008732A0 (en) 2013-03-15 2014-03-14 Human pac1 antibodies

Country Status (24)

Country Link
US (7) US9676851B2 (xx)
EP (2) EP2970470B1 (xx)
JP (3) JP6283408B2 (xx)
KR (1) KR102215405B1 (xx)
CN (1) CN105143267B (xx)
AP (1) AP2015008732A0 (xx)
AR (1) AR095611A1 (xx)
AU (2) AU2014228924B2 (xx)
CA (1) CA2906737C (xx)
CL (1) CL2015002750A1 (xx)
CR (1) CR20150575A (xx)
EA (1) EA032830B1 (xx)
ES (1) ES2770976T3 (xx)
HK (2) HK1218554A1 (xx)
IL (2) IL241382A0 (xx)
MA (1) MA38478A1 (xx)
MX (1) MX2015013181A (xx)
PE (1) PE20151923A1 (xx)
PH (1) PH12015502126A1 (xx)
SG (1) SG11201507416WA (xx)
TN (1) TN2015000425A1 (xx)
TW (2) TW201902931A (xx)
UY (1) UY35483A (xx)
WO (1) WO2014144632A2 (xx)

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WO2016044224A1 (en) 2014-09-15 2016-03-24 Amgen Inc. Bi-specific anti-cgrp receptor/pac1 receptor antigen binding proteins and uses thereof
EP3283169A4 (en) 2015-04-16 2019-03-20 Alder Biopharmaceuticals, Inc. USE OF ANTI-PACAP ANTIBODIES AND ANTIGEN-BINDING FRAGMENTS THEREOF FOR THE TREATMENT, PREVENTION OR INHIBITION OF PHOTOPHOBY
JOP20200116A1 (ar) 2015-04-24 2017-06-16 Amgen Inc طرق لعلاج أو الوقاية من الصداع النصفي
EA039859B1 (ru) * 2016-02-03 2022-03-21 Эмджен Рисерч (Мюник) Гмбх Биспецифические конструкты антител, связывающие egfrviii и cd3
CN109311977B (zh) 2016-04-15 2022-06-14 H.伦德贝克公司 人源化的抗pacap抗体及其用途
AR113022A1 (es) * 2017-09-29 2020-01-15 Lilly Co Eli Anticuerpo anti-pacap
CN111164101A (zh) * 2017-10-04 2020-05-15 安进公司 甲状腺素视黄质运载蛋白免疫球蛋白融合体
US11773171B2 (en) 2017-12-19 2023-10-03 Surrozen Operating, Inc. WNT surrogate molecules and uses thereof
US11746150B2 (en) 2017-12-19 2023-09-05 Surrozen Operating, Inc. Anti-LRP5/6 antibodies and methods of use
BR112020013621A2 (pt) 2018-01-12 2020-12-01 Amgen Inc. anticorpos contra pac1 e usos dos mesmos
EA202092335A1 (ru) 2018-04-02 2021-01-22 Эмджен Инк. Композиции на основе эренумаба и пути их применения
CA3096374A1 (en) 2018-04-12 2019-10-17 Amgen Inc. Methods for making stable protein compositions
EP3990493A1 (en) 2019-06-28 2022-05-04 Amgen Inc. Anti-cgrp receptor/anti-pac1 receptor bispecific antigen binding proteins
WO2023015298A1 (en) * 2021-08-06 2023-02-09 Amgen Inc. Isolation of therapeutic protein
CN117916259A (zh) * 2021-09-30 2024-04-19 江苏恒瑞医药股份有限公司 特异性结合cgrp和pacap的抗原结合分子及其医药用途

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Also Published As

Publication number Publication date
CL2015002750A1 (es) 2016-03-04
BR112015023429A2 (pt) 2017-11-28
CR20150575A (es) 2016-01-06
JP2019024501A (ja) 2019-02-21
IL241382A0 (en) 2015-11-30
JP6443870B2 (ja) 2018-12-26
IL262804A (en) 2018-12-31
US10294298B2 (en) 2019-05-21
AR095611A1 (es) 2015-10-28
JP6283408B2 (ja) 2018-02-21
US9365653B2 (en) 2016-06-14
CN105143267B (zh) 2020-06-26
HK1219958A1 (zh) 2017-04-21
AU2019204980A1 (en) 2019-08-01
KR102215405B1 (ko) 2021-02-10
AU2014228924A1 (en) 2015-10-01
EP2970470A2 (en) 2016-01-20
TW201902931A (zh) 2019-01-16
WO2014144632A3 (en) 2014-11-20
PE20151923A1 (es) 2016-01-14
US10472417B2 (en) 2019-11-12
EA201591791A1 (ru) 2016-03-31
US20180094055A1 (en) 2018-04-05
WO2014144632A8 (en) 2015-12-30
US20200172614A1 (en) 2020-06-04
UY35483A (es) 2014-08-29
US9676851B2 (en) 2017-06-13
AU2014228924B2 (en) 2019-04-18
US20180362645A1 (en) 2018-12-20
SG11201507416WA (en) 2015-10-29
TN2015000425A1 (en) 2017-01-03
ES2770976T3 (es) 2020-07-06
TWI636064B (zh) 2018-09-21
US9822178B2 (en) 2017-11-21
CN105143267A (zh) 2015-12-09
TW201522375A (zh) 2015-06-16
US20160251432A1 (en) 2016-09-01
CA2906737A1 (en) 2014-09-18
JP2016514458A (ja) 2016-05-23
WO2014144632A2 (en) 2014-09-18
US20150010560A1 (en) 2015-01-08
JP2018076373A (ja) 2018-05-17
HK1218554A1 (zh) 2017-02-24
BR112015023429A8 (pt) 2018-01-23
US20160039939A1 (en) 2016-02-11
EP3683237A1 (en) 2020-07-22
AU2014228924A9 (en) 2016-06-16
US10793631B2 (en) 2020-10-06
EP2970470B1 (en) 2019-12-04
PH12015502126A1 (en) 2016-01-25
MA38478A1 (fr) 2017-11-30
US10053507B2 (en) 2018-08-21
MX2015013181A (es) 2015-12-11
CA2906737C (en) 2023-08-15
US20170247451A1 (en) 2017-08-31
EA032830B1 (ru) 2019-07-31
KR20150128982A (ko) 2015-11-18

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