ZW7683A1 - Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine h2 receptor antagonist activity - Google Patents

Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine h2 receptor antagonist activity

Info

Publication number
ZW7683A1
ZW7683A1 ZW76/83A ZW7683A ZW7683A1 ZW 7683 A1 ZW7683 A1 ZW 7683A1 ZW 76/83 A ZW76/83 A ZW 76/83A ZW 7683 A ZW7683 A ZW 7683A ZW 7683 A1 ZW7683 A1 ZW 7683A1
Authority
ZW
Zimbabwe
Prior art keywords
thiadiazoles
histamine
diamino
substituted
receptor antagonist
Prior art date
Application number
ZW76/83A
Other languages
English (en)
Inventor
Rozwie Ray Crenshaw
Aldo Antonio Algieri
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ZW7683A1 publication Critical patent/ZW7683A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZW76/83A 1982-03-29 1983-03-25 Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine h2 receptor antagonist activity ZW7683A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36320782A 1982-03-29 1982-03-29

Publications (1)

Publication Number Publication Date
ZW7683A1 true ZW7683A1 (en) 1984-01-04

Family

ID=23429274

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW76/83A ZW7683A1 (en) 1982-03-29 1983-03-25 Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine h2 receptor antagonist activity

Country Status (30)

Country Link
JP (2) JPS58180477A (sv)
KR (1) KR880002209B1 (sv)
AT (1) AT386599B (sv)
AU (2) AU557577B2 (sv)
BE (1) BE896291A (sv)
CH (2) CH660880A5 (sv)
CS (2) CS250240B2 (sv)
DD (2) DD219768A5 (sv)
DE (1) DE3311281A1 (sv)
DK (2) DK166677B1 (sv)
ES (3) ES520982A0 (sv)
FR (2) FR2542741B1 (sv)
GB (2) GB2117769B (sv)
GR (1) GR78524B (sv)
HU (2) HU196386B (sv)
IE (1) IE55596B1 (sv)
IL (1) IL68259A0 (sv)
IT (1) IT1164633B (sv)
LU (1) LU84716A1 (sv)
MY (1) MY8700942A (sv)
NL (1) NL8301063A (sv)
NO (1) NO163055C (sv)
NZ (1) NZ203726A (sv)
OA (1) OA07356A (sv)
PT (1) PT76459B (sv)
SE (2) SE461040B (sv)
SU (2) SU1419518A3 (sv)
YU (1) YU44849B (sv)
ZA (1) ZA832154B (sv)
ZW (1) ZW7683A1 (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2222083A (en) * 1982-12-14 1984-06-21 Smith Kline & French Laboratories Limited Pyridine derivatives
US4593039A (en) * 1984-04-02 1986-06-03 Merck & Co., Inc. 1-aryloxy-3-(substituted aminoalkylamino)-2-propanols
US4644006A (en) * 1984-06-22 1987-02-17 Bristol-Myers Company Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity
JPH0622828B2 (ja) * 1986-06-30 1994-03-30 フアナツク株式会社 直圧式型締機構
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3018289A (en) * 1960-02-10 1962-01-23 Wyandotte Chemicals Corp Process for preparing oxamidines
GB1595291A (en) * 1976-09-21 1981-08-12 Smith Kline French Lab Pyrimidone and thiopyrimidone derivatives
NL189197C (nl) * 1979-09-04 1993-02-01 Bristol Myers Squibb Co 3,4-digesubstitueerde-1,2,5-thiadiazool-1-oxiden en 1,1-dioxiden, bereiding daarvan alsmede farmaceutische preparaten.
DE3175201D1 (en) * 1980-04-30 1986-10-02 Merck & Co Inc Aminothiadiazoles as gastric secretion inhibitors
AU2222083A (en) * 1982-12-14 1984-06-21 Smith Kline & French Laboratories Limited Pyridine derivatives

Also Published As

Publication number Publication date
GB2117769A (en) 1983-10-19
OA07356A (fr) 1984-08-31
ES8404683A1 (es) 1984-05-16
MY8700942A (en) 1987-12-31
ES8505978A1 (es) 1985-06-16
FR2597867A1 (fr) 1987-10-30
NO163055B (no) 1989-12-18
SE8704689L (sv) 1987-11-25
DE3311281A1 (de) 1983-11-24
NL8301063A (nl) 1983-10-17
FR2597867B1 (fr) 1989-12-08
FR2542741A1 (fr) 1984-09-21
DD219768A5 (de) 1985-03-13
IE830686L (en) 1983-09-29
GR78524B (sv) 1984-09-27
NZ203726A (en) 1986-05-09
ZA832154B (en) 1983-12-28
ES8505977A1 (es) 1985-06-16
SU1355123A3 (ru) 1987-11-23
DD210909A5 (de) 1984-06-27
DK141383D0 (da) 1983-03-28
ATA111083A (de) 1988-02-15
DK81192D0 (da) 1992-06-18
AU6327286A (en) 1987-01-08
SU1419518A3 (ru) 1988-08-23
AU586037B2 (en) 1989-06-29
GB2149406B (en) 1986-01-02
PT76459B (en) 1986-03-11
AU1290783A (en) 1983-10-06
DK81192A (da) 1992-06-18
SE8301725D0 (sv) 1983-03-28
JPS58180477A (ja) 1983-10-21
IE55596B1 (en) 1990-11-21
IT8348005A0 (it) 1983-03-28
GB2149406A (en) 1985-06-12
HU196386B (en) 1988-11-28
YU74483A (en) 1986-02-28
YU44849B (en) 1991-04-30
DK166677B1 (da) 1993-06-28
AT386599B (de) 1988-09-12
CS250229B2 (en) 1987-04-16
IL68259A0 (en) 1983-06-15
GB8308518D0 (en) 1983-05-05
KR880002209B1 (ko) 1988-10-18
AU557577B2 (en) 1986-12-24
JPH0568472B2 (sv) 1993-09-29
SE461040B (sv) 1989-12-18
HU188742B (en) 1986-05-28
CH655111A5 (de) 1986-03-27
GB2117769B (en) 1985-08-29
SE464302B (sv) 1991-04-08
PT76459A (en) 1983-04-01
JPH06135925A (ja) 1994-05-17
ES527685A0 (es) 1985-06-16
FR2542741B1 (fr) 1989-12-08
IT1164633B (it) 1987-04-15
DK141383A (da) 1983-09-30
LU84716A1 (fr) 1983-12-05
ES520982A0 (es) 1984-05-16
KR840004095A (ko) 1984-10-06
CS250240B2 (en) 1987-04-16
ES527686A0 (es) 1985-06-16
NO163055C (no) 1990-03-28
NO831100L (no) 1983-09-30
BE896291A (fr) 1983-09-28
GB8432809D0 (en) 1985-02-06
SE8704689D0 (sv) 1987-11-25
CH660880A5 (de) 1987-05-29
SE8301725L (sv) 1983-11-25

Similar Documents

Publication Publication Date Title
GB2131428B (en) Amine derivatives having histamine h2-blocking activity
GB2135311B (en) Novel xanthine-type adenosine receptor antagonists
ZA801002B (en) Histamine antagonists
GB8510455D0 (en) 2-1,2,4-triazolin-5-one derivatives
IL79215A0 (en) Substituted 4,5-dihydro-1,3,4-thiadiazoles
ZW7683A1 (en) Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine h2 receptor antagonist activity
ZA858891B (en) V1-vasopressin antagonists
ZA783141B (en) Histamine h2 receptor antagonists
EP0276057A3 (en) Piperazinylpyrimidines as b-adrenergic receptor blocking agents
ZA894097B (en) Alpha-adrenergic receptor antagonists
ZA854710B (en) Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine h2-receptor antagonist activity
ZM4984A1 (en) 2,5-disubstituted-4(3h)-pyrimidones having histamine h2-recepter antagonist activity
GB2137197B (en) Thicro-thiazole h2 antagonists
AU5067985A (en) 1,2,4-thiadiazole derivatives
IE842242L (en) Solid state x-ray receptor
IE810940L (en) 17-substituted-6-desoxy-7,8-dihydro-6ó-methylnoroxymorphone¹narcotic antagonists
IE820466L (en) 2-amino-5-(sulphamidophenyl)-1,3,4-thiadiazoles, anti-viral¹agents
IE811414L (en) Imidazolidines, microbicides
ZA892737B (en) Azabiocyclic compounds having 5-ht3 receptor antagonist activity
IE842767L (en) Leukotriene antagonists.
IE881220L (en) 5-ht3 receptor antagonists
IE841246L (en) Pyridines, microbicides
CS285084A1 (en) Vozidlo s diferencovanym pohonem hnacich kolies, regulovanym od riadiaceho mechanizmu
SU1221878A1 (ru) I′ -БЕНЗИЛ-5,7-ДИМЕТИЛ-6-ОКСОСПИРО-(1,3-ДИАЗААДАМАНТАН- 2,4′ -ПИПЕРИДИН), ОБЛАДАЮЩИЙ α -АДРЕНОБЛОКИРУЮЩЕЙ АКТИВНОСТЬЮ
IE831350L (en) Bis-1,2,4-triazoles.