ZA99533B - Glucocortiocoid-selective antiinflammatory agents. - Google Patents
Glucocortiocoid-selective antiinflammatory agents.Info
- Publication number
- ZA99533B ZA99533B ZA9900533A ZA99533A ZA99533B ZA 99533 B ZA99533 B ZA 99533B ZA 9900533 A ZA9900533 A ZA 9900533A ZA 99533 A ZA99533 A ZA 99533A ZA 99533 B ZA99533 B ZA 99533B
- Authority
- ZA
- South Africa
- Prior art keywords
- glucocortiocoid
- mammal
- antiinflammatory agents
- compounds
- formula
- Prior art date
Links
- 229940121363 anti-inflammatory agent Drugs 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 3
- 208000023275 Autoimmune disease Diseases 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000026278 immune system disease Diseases 0.000 abstract 2
- 102000003676 Glucocorticoid Receptors Human genes 0.000 abstract 1
- 108090000079 Glucocorticoid Receptors Proteins 0.000 abstract 1
- 241000845077 Iare Species 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 230000001363 autoimmune Effects 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000754 repressing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cephalosporin Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/023,913 US6380207B2 (en) | 1998-02-13 | 1998-02-13 | Glucocortiocoid-selective antiinflammatory agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA99533B true ZA99533B (en) | 1999-07-26 |
Family
ID=21817891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9900533A ZA99533B (en) | 1998-02-13 | 1999-01-25 | Glucocortiocoid-selective antiinflammatory agents. |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6380207B2 (es) |
| EP (1) | EP1053240B1 (es) |
| JP (1) | JP2002503666A (es) |
| KR (1) | KR20010040940A (es) |
| CN (1) | CN1153771C (es) |
| AT (1) | ATE237620T1 (es) |
| AU (1) | AU760511B2 (es) |
| BG (1) | BG64213B1 (es) |
| BR (1) | BR9907847A (es) |
| CA (1) | CA2320911A1 (es) |
| DE (1) | DE69906938T2 (es) |
| DK (1) | DK1053240T3 (es) |
| ES (1) | ES2197618T3 (es) |
| HU (1) | HUP0100846A3 (es) |
| IL (1) | IL137509A0 (es) |
| NO (1) | NO20004052L (es) |
| NZ (1) | NZ506012A (es) |
| PL (1) | PL342999A1 (es) |
| PT (1) | PT1053240E (es) |
| SK (1) | SK284076B6 (es) |
| TR (1) | TR200002345T2 (es) |
| WO (1) | WO1999041257A1 (es) |
| ZA (1) | ZA99533B (es) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6566372B1 (en) * | 1999-08-27 | 2003-05-20 | Ligand Pharmaceuticals Incorporated | Bicyclic androgen and progesterone receptor modulator compounds and methods |
| ES2246292T3 (es) | 2000-10-30 | 2006-02-16 | Pfizer Products Inc. | Moduladores de receptor glucocorticoide. |
| US7026484B2 (en) * | 2001-02-23 | 2006-04-11 | Ligand Pharmaceuticals Incorporated | Tricyclic androgen receptor modulator compounds and methods |
| WO2003061651A1 (en) | 2002-01-22 | 2003-07-31 | The Regents Of The University Of California | Non-steroidal ligands for the glucocorticoid receptor, compositions and uses thereof |
| KR100492913B1 (ko) * | 2002-08-23 | 2005-06-03 | 주식회사 태평양 | 피부 감작 및 자극을 완화하는 피부 외용제 조성물 |
| US20040138187A1 (en) | 2002-08-28 | 2004-07-15 | Reading Christopher L. | Therapeutic treatment methods |
| US20040220153A1 (en) * | 2002-09-24 | 2004-11-04 | Jost-Price Edward Roydon | Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines |
| JP2006508076A (ja) * | 2002-10-11 | 2006-03-09 | リガンド・ファーマシューティカルズ・インコーポレイテッド | 選択的プロゲステロン受容体モジュレーター化合物としての５−シクロアルケニル５Ｈ−クロメノ［３，４−ｆ］キノリン誘導体 |
| DE20301728U1 (de) * | 2002-10-11 | 2004-03-11 | Ligand Pharmaceuticals, Inc., San Diego | 5-substituierte 7,9-Difluor-5H-Chromeno(3,4-f) -Chinolin-Verbindungen als selektive Progesteronrezeptormodulator-Verbindungen |
| MXPA05003800A (es) * | 2002-10-11 | 2005-06-08 | Ligand Pharm Inc | 5-(1¦,1¦-cicloalquil/alquenil)metiliden 1,2-dihidro-5h- cromeno[3,4f]quinolinas como compuestos moduladores de receptor de progesterona selectivos. |
| US7235662B2 (en) * | 2003-06-11 | 2007-06-26 | Bristol-Myers Squibb Company | Modulators of the glucocorticoid receptor and method |
| EP1656142A4 (en) * | 2003-08-22 | 2011-06-22 | Ligand Pharm Inc | 6-CYCLOAMINO-2-QUINOLINONE DERIVATIVES AS MODULATORS ANDROGEN RECEPTOR COMPOUNDS |
| TW200517114A (en) | 2003-10-15 | 2005-06-01 | Combinatorx Inc | Methods and reagents for the treatment of immunoinflammatory disorders |
| BRPI0416812A (pt) | 2003-11-21 | 2007-03-06 | Combinatorx Inc | métodos e reagentes para o tratamento de desordens inflamatórias |
| US8519158B2 (en) * | 2004-03-12 | 2013-08-27 | Ligand Pharmaceuticals Incorporated | Androgen receptor modulator compounds and methods |
| AU2006259474B2 (en) | 2005-06-17 | 2011-10-27 | Ligand Pharmaceuticals Incorporated | Androgen receptor modulator compounds and methods |
| US7645885B2 (en) | 2005-08-26 | 2010-01-12 | The Regents Of The University Of California | Non-steroidal antiandrogens |
| BRPI0618643A2 (pt) | 2005-11-09 | 2011-09-06 | Combinatorx Inc | composição compreendendo um par de fármacos, composição compreendendo um corticosteróide e um imunossupressor dependente de imunofilina não-esteróide, kits e uso |
| CN101326155B (zh) * | 2005-12-09 | 2012-06-20 | 霍夫曼-拉罗奇有限公司 | 作为抗炎剂的丙酰胺化合物 |
| EP1963287A1 (en) * | 2005-12-09 | 2008-09-03 | F.Hoffmann-La Roche Ag | Glucocorticoid receptor modulators as antiinflammatory agents |
| US8269612B2 (en) | 2008-07-10 | 2012-09-18 | Black & Decker Inc. | Communication protocol for remotely controlled laser devices |
| US20100092479A1 (en) * | 2008-08-18 | 2010-04-15 | Combinatorx (Singapore) Pte. Ltd. | Compositions and methods for treatment of viral diseases |
| US9908182B2 (en) | 2012-01-30 | 2018-03-06 | Black & Decker Inc. | Remote programming of a power tool |
| US20130327552A1 (en) | 2012-06-08 | 2013-12-12 | Black & Decker Inc. | Power tool having multiple operating modes |
| US8919456B2 (en) | 2012-06-08 | 2014-12-30 | Black & Decker Inc. | Fastener setting algorithm for drill driver |
| US10011006B2 (en) | 2013-08-08 | 2018-07-03 | Black & Decker Inc. | Fastener setting algorithm for drill driver |
| EP3956309A4 (en) | 2019-04-19 | 2023-06-07 | Ligand Pharmaceuticals Inc. | CRYSTALLINE FORMS AND METHODS FOR PRODUCING CRYSTALLINE FORMS OF A COMPOUND |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1043326A1 (en) | 1994-12-22 | 2000-10-11 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
| US5696127A (en) | 1994-12-22 | 1997-12-09 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
| US5693133A (en) | 1995-05-10 | 1997-12-02 | Akzo Nobel Nv | Asbestos free roof coatings |
-
1998
- 1998-02-13 US US09/023,913 patent/US6380207B2/en not_active Expired - Fee Related
-
1999
- 1999-01-25 ZA ZA9900533A patent/ZA99533B/xx unknown
- 1999-02-15 EP EP99905971A patent/EP1053240B1/en not_active Expired - Lifetime
- 1999-02-15 DK DK99905971T patent/DK1053240T3/da active
- 1999-02-15 CN CNB998050342A patent/CN1153771C/zh not_active Expired - Fee Related
- 1999-02-15 AT AT99905971T patent/ATE237620T1/de not_active IP Right Cessation
- 1999-02-15 PL PL99342999A patent/PL342999A1/xx unknown
- 1999-02-15 NZ NZ506012A patent/NZ506012A/xx unknown
- 1999-02-15 DE DE69906938T patent/DE69906938T2/de not_active Expired - Fee Related
- 1999-02-15 PT PT99905971T patent/PT1053240E/pt unknown
- 1999-02-15 ES ES99905971T patent/ES2197618T3/es not_active Expired - Lifetime
- 1999-02-15 TR TR2000/02345T patent/TR200002345T2/xx unknown
- 1999-02-15 WO PCT/US1999/003210 patent/WO1999041257A1/en not_active Ceased
- 1999-02-15 AU AU26003/99A patent/AU760511B2/en not_active Ceased
- 1999-02-15 HU HU0100846A patent/HUP0100846A3/hu unknown
- 1999-02-15 CA CA002320911A patent/CA2320911A1/en not_active Abandoned
- 1999-02-15 SK SK1196-2000A patent/SK284076B6/sk unknown
- 1999-02-15 JP JP2000531450A patent/JP2002503666A/ja not_active Withdrawn
- 1999-02-15 KR KR1020007008857A patent/KR20010040940A/ko not_active Ceased
- 1999-02-15 IL IL13750999A patent/IL137509A0/xx unknown
- 1999-02-15 BR BR9907847-3A patent/BR9907847A/pt not_active IP Right Cessation
-
2000
- 2000-08-11 NO NO20004052A patent/NO20004052L/no not_active Application Discontinuation
- 2000-08-17 BG BG104698A patent/BG64213B1/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE237620T1 (de) | 2003-05-15 |
| BR9907847A (pt) | 2001-01-09 |
| US6380207B2 (en) | 2002-04-30 |
| HUP0100846A2 (hu) | 2001-09-28 |
| AU760511B2 (en) | 2003-05-15 |
| DK1053240T3 (da) | 2003-08-11 |
| BG64213B1 (bg) | 2004-05-31 |
| PL342999A1 (en) | 2001-07-16 |
| NO20004052L (no) | 2000-10-12 |
| CN1153771C (zh) | 2004-06-16 |
| HUP0100846A3 (en) | 2003-03-28 |
| JP2002503666A (ja) | 2002-02-05 |
| US20010049377A1 (en) | 2001-12-06 |
| KR20010040940A (ko) | 2001-05-15 |
| IL137509A0 (en) | 2001-07-24 |
| CN1297451A (zh) | 2001-05-30 |
| SK11962000A3 (sk) | 2001-03-12 |
| DE69906938D1 (de) | 2003-05-22 |
| CA2320911A1 (en) | 1999-08-19 |
| TR200002345T2 (tr) | 2000-11-21 |
| EP1053240A1 (en) | 2000-11-22 |
| NZ506012A (en) | 2003-03-28 |
| ES2197618T3 (es) | 2004-01-01 |
| NO20004052D0 (no) | 2000-08-11 |
| DE69906938T2 (de) | 2004-02-26 |
| SK284076B6 (sk) | 2004-09-08 |
| HK1033309A1 (en) | 2001-08-24 |
| AU2600399A (en) | 1999-08-30 |
| PT1053240E (pt) | 2003-09-30 |
| EP1053240B1 (en) | 2003-04-16 |
| WO1999041257A1 (en) | 1999-08-19 |
| BG104698A (en) | 2001-05-31 |
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