ZA993777B - Non-peptidyl inhibitors of vla-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases. - Google Patents

Non-peptidyl inhibitors of vla-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases.

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Publication number
ZA993777B
ZA993777B ZA9903777A ZA993777A ZA993777B ZA 993777 B ZA993777 B ZA 993777B ZA 9903777 A ZA9903777 A ZA 9903777A ZA 993777 A ZA993777 A ZA 993777A ZA 993777 B ZA993777 B ZA 993777B
Authority
ZA
South Africa
Prior art keywords
vla
autoimmune
cell binding
dependent cell
respiratory diseases
Prior art date
Application number
ZA9903777A
Other languages
English (en)
Inventor
Allen Jacob Duplantier
Anthony John Milici
Louis Stanley Chupak
Original Assignee
Pfizer Prod Inc
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Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ZA993777B publication Critical patent/ZA993777B/xx

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    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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ZA9903777A 1998-06-30 1999-06-04 Non-peptidyl inhibitors of vla-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases. ZA993777B (en)

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CN1319094A (zh) 1998-06-12 2001-10-24 研究及应用科学协会股份有限公司 咪唑基衍生物
BR9911701A (pt) * 1998-06-30 2001-03-20 Pfizer Prod Inc Inibidores não peptidila da ligação à célula dependente de vla-4 úteis no tratamento de doenças inflamatórias, auto-imunes e respiratórias
US6518292B1 (en) * 1999-03-12 2003-02-11 Bristol-Myers Squibb Co. Heterocyclic aromatic compounds usefuls as growth hormone secretagogues
US6756378B2 (en) * 1999-06-30 2004-06-29 Pharmacopeia Drug Discovery, Inc. VLA-4 inhibitor compounds
IL146288A0 (en) * 1999-06-30 2002-07-25 Daiichi Seiyaku Co Vla-4 inhibitor compounds
BR0016818A (pt) * 1999-12-28 2002-10-01 Pfizer Prod Inc Inibidores não-peptidila de adesão celular dependente de vla-4 úteis no tratamento de doenças inflamatórias, auto-imunes e respiratórias
AU2001234741A1 (en) * 2000-02-04 2001-08-14 Biogen, Inc. Integrin antagonists
EP1296949A2 (en) * 2000-06-21 2003-04-02 Bristol-Myers Squibb Pharma Company Piperidine amides as modulators of chemokine receptor activity
KR20030020960A (ko) 2000-08-01 2003-03-10 소시에떼 더 콘세이유 더 레세르세 에 다플리까띠옹 시엔띠피끄, 에스.아.에스. 이미다졸일 유도체
GB2367816A (en) 2000-10-09 2002-04-17 Bayer Ag Urea- and thiourea-containing derivatives of beta-amino acids
RU2290403C2 (ru) 2000-12-28 2006-12-27 Дайити Фармасьютикал Ко., Лтд. Ингибиторы vla-4
DE10111877A1 (de) * 2001-03-10 2002-09-12 Aventis Pharma Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE60228954D1 (en) 2001-05-03 2008-10-30 Galileo Lab Inc Pyruvatderivate
JP4583751B2 (ja) * 2001-06-06 2010-11-17 アベンティス・フアーマ・リミテッド 炎症性疾患の治療に使用するための置換されたテトラヒドロイソキノリン
GB2377933A (en) 2001-07-06 2003-01-29 Bayer Ag Succinic acid derivatives useful as integrin antagonists
DE10137595A1 (de) 2001-08-01 2003-02-13 Aventis Pharma Gmbh Neue Imidazolidinderivate, ihre Herstellung und ihre Verwendung
US6974869B2 (en) * 2001-09-18 2005-12-13 Bristol-Myers Squibb Pharma Company Piperizinones as modulators of chemokine receptor activity
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TW200610754A (en) * 2004-06-14 2006-04-01 Daiichi Seiyaku Co Vla-4 inhibitor
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EP3661922A1 (en) 2017-08-04 2020-06-10 Dyax Corp. Inhibitors of plasma kallikrein and uses thereof
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NZ508033A (en) 2002-12-20
PA8477001A1 (es) 2000-05-24
CZ20004909A3 (cs) 2002-04-17
IL139584A0 (en) 2002-02-10
MA26640A1 (fr) 2004-12-20
SK20052000A3 (sk) 2002-08-06
GT199900101A (es) 2000-12-16
EA200001238A1 (ru) 2001-08-27
AP1236A (en) 2004-01-14
NO20006600L (no) 2001-02-21
DE69928667D1 (de) 2006-01-05
WO2000000477A1 (en) 2000-01-06
IS5720A (is) 2000-11-21
EA004792B1 (ru) 2004-08-26
PE20000762A1 (es) 2000-08-24
JP2002519344A (ja) 2002-07-02
CA2336625A1 (en) 2000-01-06
EP1091943A1 (en) 2001-04-18
CO5320599A1 (es) 2003-09-30
NO20006600D0 (no) 2000-12-22
AR015312A1 (es) 2001-04-18
AP9901561A0 (en) 1999-06-30
AU3841699A (en) 2000-01-17
HN1999000099A (es) 1999-11-11
TNSN99110A1 (fr) 2005-11-10
AU758939B2 (en) 2003-04-03
OA11577A (en) 2004-07-26
HUP0102477A3 (en) 2002-08-28
CN1308616A (zh) 2001-08-15
UA66864C2 (uk) 2004-06-15
TR200003848T2 (tr) 2001-06-21
HRP20000917A2 (en) 2002-02-28
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BG105190A (en) 2001-12-29
DE69928667T2 (de) 2006-08-10
US6355662B1 (en) 2002-03-12
HUP0102477A2 (hu) 2002-05-29
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