PL339493A1 - Bis-ethers of 1-oxa, aza and thinaphtalen-2-ones as phospholamane inhibitors - Google Patents

Bis-ethers of 1-oxa, aza and thinaphtalen-2-ones as phospholamane inhibitors

Info

Publication number
PL339493A1
PL339493A1 PL98339493A PL33949398A PL339493A1 PL 339493 A1 PL339493 A1 PL 339493A1 PL 98339493 A PL98339493 A PL 98339493A PL 33949398 A PL33949398 A PL 33949398A PL 339493 A1 PL339493 A1 PL 339493A1
Authority
PL
Poland
Prior art keywords
thinaphtalen
phospholamane
aza
oxa
ethers
Prior art date
Application number
PL98339493A
Original Assignee
Orion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corp filed Critical Orion Corp
Publication of PL339493A1 publication Critical patent/PL339493A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
PL98339493A 1997-09-24 1998-09-24 Bis-ethers of 1-oxa, aza and thinaphtalen-2-ones as phospholamane inhibitors PL339493A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US93711997A 1997-09-24 1997-09-24
US99015097A 1997-12-12 1997-12-12
US10411498A 1998-06-25 1998-06-25

Publications (1)

Publication Number Publication Date
PL339493A1 true PL339493A1 (en) 2000-12-18

Family

ID=27379660

Family Applications (1)

Application Number Title Priority Date Filing Date
PL98339493A PL339493A1 (en) 1997-09-24 1998-09-24 Bis-ethers of 1-oxa, aza and thinaphtalen-2-ones as phospholamane inhibitors

Country Status (18)

Country Link
EP (1) EP1017691A1 (en)
JP (1) JP2003525838A (en)
KR (1) KR20010015607A (en)
CN (1) CN1143857C (en)
AU (1) AU735729B2 (en)
BR (1) BR9813216A (en)
CA (1) CA2304849A1 (en)
EA (1) EA003084B1 (en)
EE (1) EE04494B1 (en)
HU (1) HUP0003647A3 (en)
ID (1) ID24373A (en)
IL (1) IL134662A0 (en)
NO (1) NO20001569L (en)
NZ (1) NZ503044A (en)
PL (1) PL339493A1 (en)
SK (1) SK3902000A3 (en)
TR (1) TR200000764T2 (en)
WO (1) WO1999015523A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4890723B2 (en) * 2000-07-21 2012-03-07 中外製薬株式会社 Coumarin derivatives useful as TNFα inhibitors
GEP20053675B (en) * 2001-03-30 2005-11-25 Pfizer Prod Inc Pyridazinone Aldose Reductase Inhibitors
US7572910B2 (en) 2003-02-20 2009-08-11 Pfizer, Inc. Pyridazinone aldose reductase inhibitors
FR2970964B1 (en) * 2011-01-28 2013-12-13 Univ Claude Bernard Lyon NOVEL AZACOUMARIN DERIVATIVES WITH INHIBITOR ACTIVITY OF MDR PUMPS

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2543945A1 (en) * 1975-10-02 1977-04-21 Troponwerke Gmbh & Co Kg Coronary dilator 2-benzopyranones, active by enteral admin. - contg. trimethoxybenzoyl or trimethoxycinnamoyl substits.
GB8529362D0 (en) * 1985-11-28 1986-01-02 Pfizer Ltd Quinolone cardiac stimulants
GB8630702D0 (en) * 1986-12-23 1987-02-04 Wellcome Found Quinoline compound
EP0355583B1 (en) * 1988-08-10 1995-01-25 Otsuka Pharmaceutical Co., Ltd. Cardiotonics
CA2022236A1 (en) * 1989-07-31 1991-02-01 Hiroaki Yanagisawa Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders
DE4337906A1 (en) * 1993-11-08 1995-05-11 Cassella Ag Use of coumarin derivatives

Also Published As

Publication number Publication date
EA200000352A1 (en) 2000-10-30
KR20010015607A (en) 2001-02-26
BR9813216A (en) 2000-08-29
CN1271357A (en) 2000-10-25
NO20001569D0 (en) 2000-03-24
IL134662A0 (en) 2001-04-30
NZ503044A (en) 2001-08-31
TR200000764T2 (en) 2001-03-21
HUP0003647A2 (en) 2001-08-28
EE04494B1 (en) 2005-06-15
ID24373A (en) 2000-07-13
AU735729B2 (en) 2001-07-12
CN1143857C (en) 2004-03-31
NO20001569L (en) 2000-03-24
WO1999015523A1 (en) 1999-04-01
SK3902000A3 (en) 2000-12-11
HUP0003647A3 (en) 2002-12-28
CA2304849A1 (en) 1999-04-01
EA003084B1 (en) 2002-12-26
JP2003525838A (en) 2003-09-02
EE200000179A (en) 2001-04-16
EP1017691A1 (en) 2000-07-12
AU9350898A (en) 1999-04-12

Similar Documents

Publication Publication Date Title
EP1018987A4 (en) Neocartilage and methods of use
EP1009415A4 (en) INHIBITORS OF $g(b)-LACTAMASES AND USES THEREFOR
PL331900A1 (en) 1,4-heterocyclic inhibitors of metaloprotease
PL334846A1 (en) Sulphamidic inhibitors of metaloproteases
PL331838A1 (en) 1,3-diheterocyclic inhibitors of metaloproteases
ZA98376B (en) Sulfamide-metalloprotease inhibitors
HK1044545A1 (en) Human beta-secretase enzyme, inhibitors and their compositions and uses
HUP9800634A3 (en) P-amidino-benzylamide derivatives as thrombin inhibitors, intermediates and use thereof
PL337645A1 (en) Novel amidine derivatives and their application as thrombosin inhibitors
HK1008995A1 (en) New thrombin inhibitors, their preparation and use
PL331047A1 (en) Novel amidinic derivatives and their application as inhibitors of thrombosin
IL133368A0 (en) Urokinase inhibitors
ZA971964B (en) Azolobenzazepine derivatives and compositions and method of use thereof.
HU0900792D0 (en) Use of renin-angiotensin inhibitors
AU5463099A (en) Inhibitors of redox signaling and methods of using same
GB2346823B (en) Reamer and method of using the same
HUP9904165A3 (en) 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase and use thereof
HK1048318B (en) Substituted 3-phenyl-5-alkoxi-1, 3,4-oxdiazol-2-ones and their use as lipase inhibitors
GB9725114D0 (en) Treatment of pruritus
ZA200006020B (en) Voacamine as anti-malarial agent and anti-malarial agent containing voacamine.
AU9569998A (en) Photo-spectrometers, methods of use and manufacture
ZA9710989B (en) Polyprolyl inhibitors of cyclophilin
HUP9800146A3 (en) Thalidomide-derivatives and use of them
PL339493A1 (en) Bis-ethers of 1-oxa, aza and thinaphtalen-2-ones as phospholamane inhibitors
GB9814269D0 (en) 9a-Aza-3-ketolides, compositions containing such compounds and methods of treatment