EE04494B1 - 1-Oxa, aza and thianaphthalen-2-one biseters as phospholambane inhibitors - Google Patents
1-Oxa, aza and thianaphthalen-2-one biseters as phospholambane inhibitorsInfo
- Publication number
- EE04494B1 EE04494B1 EEP200000179A EEP200000179A EE04494B1 EE 04494 B1 EE04494 B1 EE 04494B1 EE P200000179 A EEP200000179 A EE P200000179A EE P200000179 A EEP200000179 A EE P200000179A EE 04494 B1 EE04494 B1 EE 04494B1
- Authority
- EE
- Estonia
- Prior art keywords
- thianaphthalen
- phospholambane
- biseters
- aza
- oxa
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93711997A | 1997-09-24 | 1997-09-24 | |
| US99015097A | 1997-12-12 | 1997-12-12 | |
| US10411498A | 1998-06-25 | 1998-06-25 | |
| PCT/FI1998/000755 WO1999015523A1 (en) | 1997-09-24 | 1998-09-24 | Bisethers of 1-oxa, aza and thianaphthalen-2-ones as phospholamban inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EE200000179A EE200000179A (en) | 2001-04-16 |
| EE04494B1 true EE04494B1 (en) | 2005-06-15 |
Family
ID=27379660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200000179A EE04494B1 (en) | 1997-09-24 | 1998-09-24 | 1-Oxa, aza and thianaphthalen-2-one biseters as phospholambane inhibitors |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1017691A1 (en) |
| JP (1) | JP2003525838A (en) |
| KR (1) | KR20010015607A (en) |
| CN (1) | CN1143857C (en) |
| AU (1) | AU735729B2 (en) |
| BR (1) | BR9813216A (en) |
| CA (1) | CA2304849A1 (en) |
| EA (1) | EA003084B1 (en) |
| EE (1) | EE04494B1 (en) |
| HU (1) | HUP0003647A3 (en) |
| ID (1) | ID24373A (en) |
| IL (1) | IL134662A0 (en) |
| NO (1) | NO20001569D0 (en) |
| NZ (1) | NZ503044A (en) |
| PL (1) | PL339493A1 (en) |
| SK (1) | SK3902000A3 (en) |
| TR (1) | TR200000764T2 (en) |
| WO (1) | WO1999015523A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001278980A1 (en) | 2000-07-21 | 2002-02-05 | Chugai Seiyaku Kabushiki Kaisha | Coumarin derivatives useful as tnfalpha inhibitors |
| CA2442476A1 (en) * | 2001-03-30 | 2002-10-10 | Pfizer Products Inc. | Pyridazinone aldose reductase inhibitors |
| US7572910B2 (en) | 2003-02-20 | 2009-08-11 | Pfizer, Inc. | Pyridazinone aldose reductase inhibitors |
| FR2970964B1 (en) * | 2011-01-28 | 2013-12-13 | Univ Claude Bernard Lyon | NOVEL AZACOUMARIN DERIVATIVES WITH INHIBITOR ACTIVITY OF MDR PUMPS |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2543945A1 (en) * | 1975-10-02 | 1977-04-21 | Troponwerke Gmbh & Co Kg | Coronary dilator 2-benzopyranones, active by enteral admin. - contg. trimethoxybenzoyl or trimethoxycinnamoyl substits. |
| GB8529362D0 (en) * | 1985-11-28 | 1986-01-02 | Pfizer Ltd | Quinolone cardiac stimulants |
| GB8630702D0 (en) * | 1986-12-23 | 1987-02-04 | Wellcome Found | Quinoline compound |
| US5053514A (en) * | 1988-08-10 | 1991-10-01 | Otsuka Pharmaceutical Company, Limited | Cardiotonics |
| CA2022236A1 (en) * | 1989-07-31 | 1991-02-01 | Hiroaki Yanagisawa | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders |
| DE4337906A1 (en) * | 1993-11-08 | 1995-05-11 | Cassella Ag | Use of coumarin derivatives |
-
1998
- 1998-09-24 JP JP2000512828A patent/JP2003525838A/en active Pending
- 1998-09-24 EP EP98946482A patent/EP1017691A1/en not_active Withdrawn
- 1998-09-24 BR BR9813216-4A patent/BR9813216A/en not_active IP Right Cessation
- 1998-09-24 ID IDW20000564A patent/ID24373A/en unknown
- 1998-09-24 PL PL98339493A patent/PL339493A1/en unknown
- 1998-09-24 HU HU0003647A patent/HUP0003647A3/en unknown
- 1998-09-24 KR KR1020007003094A patent/KR20010015607A/en not_active Application Discontinuation
- 1998-09-24 WO PCT/FI1998/000755 patent/WO1999015523A1/en not_active Application Discontinuation
- 1998-09-24 CA CA002304849A patent/CA2304849A1/en not_active Abandoned
- 1998-09-24 NZ NZ503044A patent/NZ503044A/en unknown
- 1998-09-24 EA EA200000352A patent/EA003084B1/en not_active IP Right Cessation
- 1998-09-24 SK SK390-2000A patent/SK3902000A3/en unknown
- 1998-09-24 EE EEP200000179A patent/EE04494B1/en not_active IP Right Cessation
- 1998-09-24 CN CNB98809438XA patent/CN1143857C/en not_active Expired - Fee Related
- 1998-09-24 IL IL13466298A patent/IL134662A0/en unknown
- 1998-09-24 TR TR2000/00764T patent/TR200000764T2/en unknown
- 1998-09-24 AU AU93508/98A patent/AU735729B2/en not_active Ceased
-
2000
- 2000-03-24 NO NO20001569A patent/NO20001569D0/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1143857C (en) | 2004-03-31 |
| KR20010015607A (en) | 2001-02-26 |
| EE200000179A (en) | 2001-04-16 |
| NZ503044A (en) | 2001-08-31 |
| CN1271357A (en) | 2000-10-25 |
| NO20001569L (en) | 2000-03-24 |
| SK3902000A3 (en) | 2000-12-11 |
| WO1999015523A1 (en) | 1999-04-01 |
| AU735729B2 (en) | 2001-07-12 |
| NO20001569D0 (en) | 2000-03-24 |
| AU9350898A (en) | 1999-04-12 |
| EP1017691A1 (en) | 2000-07-12 |
| HUP0003647A2 (en) | 2001-08-28 |
| EA003084B1 (en) | 2002-12-26 |
| IL134662A0 (en) | 2001-04-30 |
| EA200000352A1 (en) | 2000-10-30 |
| HUP0003647A3 (en) | 2002-12-28 |
| BR9813216A (en) | 2000-08-29 |
| JP2003525838A (en) | 2003-09-02 |
| ID24373A (en) | 2000-07-13 |
| CA2304849A1 (en) | 1999-04-01 |
| TR200000764T2 (en) | 2001-03-21 |
| PL339493A1 (en) | 2000-12-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB4A | Valid patent at the end of a year |
Effective date: 20051231 |
|
| MM4A | Lapsed by not paying the annual fees |
Effective date: 20050924 |