AU2001278980A1 - Coumarin derivatives useful as tnfalpha inhibitors - Google Patents
Coumarin derivatives useful as tnfalpha inhibitorsInfo
- Publication number
- AU2001278980A1 AU2001278980A1 AU2001278980A AU7898001A AU2001278980A1 AU 2001278980 A1 AU2001278980 A1 AU 2001278980A1 AU 2001278980 A AU2001278980 A AU 2001278980A AU 7898001 A AU7898001 A AU 7898001A AU 2001278980 A1 AU2001278980 A1 AU 2001278980A1
- Authority
- AU
- Australia
- Prior art keywords
- derivatives useful
- coumarin derivatives
- tnfalpha inhibitors
- tnfalpha
- inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22004800P | 2000-07-21 | 2000-07-21 | |
US60220048 | 2000-07-21 | ||
US22544800P | 2000-08-14 | 2000-08-14 | |
US60225448 | 2000-08-14 | ||
US30303001P | 2001-07-03 | 2001-07-03 | |
US60303030 | 2001-07-03 | ||
PCT/US2001/022950 WO2002008217A2 (en) | 2000-07-21 | 2001-07-19 | COUMARIN DERIVATIVES USEFUL AS TNFα INHIBITORS |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001278980A1 true AU2001278980A1 (en) | 2002-02-05 |
Family
ID=27396753
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001278980A Abandoned AU2001278980A1 (en) | 2000-07-21 | 2001-07-19 | Coumarin derivatives useful as tnfalpha inhibitors |
Country Status (4)
Country | Link |
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US (4) | US7026491B2 (en) |
JP (1) | JP4890723B2 (en) |
AU (1) | AU2001278980A1 (en) |
WO (1) | WO2002008217A2 (en) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
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AU2003245935A1 (en) * | 2002-06-13 | 2003-12-31 | Novuspharma S.P.A. | Derivatives of chromen-2-one as inhibitors of vegf production in mammalian cells |
AR059339A1 (en) | 2006-02-09 | 2008-03-26 | Chugai Pharmaceutical Co Ltd | CUMARINE DERIVATIVES FOR PROLIFERATIVE DISORDERS OF CELLS, PHARMACEUTICAL COMPOSITION AND THERAPEUTIC AGENT CONTAINING THEM |
KR101511396B1 (en) * | 2007-07-20 | 2015-04-13 | 추가이 세이야쿠 가부시키가이샤 | p27 PROTEIN INDUCER |
JP2009084269A (en) * | 2007-09-05 | 2009-04-23 | Sumitomo Chemical Co Ltd | Coumarin compound and its use |
US10867298B1 (en) | 2008-10-31 | 2020-12-15 | Wells Fargo Bank, N.A. | Payment vehicle with on and off function |
US20100114768A1 (en) | 2008-10-31 | 2010-05-06 | Wachovia Corporation | Payment vehicle with on and off function |
WO2011072275A2 (en) * | 2009-12-11 | 2011-06-16 | Nono, Inc. | Agents and methods for treating ischemic and other diseases |
ES2379242B1 (en) * | 2010-09-28 | 2013-03-04 | Consejo Superior De Investigaciones Científicas (Csic) | CHROME DERIVATIVES |
WO2012171488A1 (en) * | 2011-06-17 | 2012-12-20 | Beijing Hanmi Pharmaceutical Co., Ltd. | Coumarin derivative, pharmaceutical composition and use thereof |
JP6061856B2 (en) * | 2011-09-05 | 2017-01-18 | 中外製薬株式会社 | Method for producing coumarin derivatives |
CN103408530B (en) * | 2013-08-26 | 2015-05-27 | 中国人民解放军第三军医大学 | Coumarin skeleton polycyclic compound with biological activity as well as preparation method and use thereof |
JP2016538331A (en) * | 2013-10-10 | 2016-12-08 | メルク パテント ゲーエムベーハー | Synthesis of 1-alkyl-2-amino-imidazole-5-carboxylic acid esters via Cα-substituted N-alkyl-glycine ester derivatives |
ES2534318B1 (en) | 2013-10-18 | 2016-01-28 | Artax Biopharma Inc. | Alkoxide substituted chromene derivatives as inhibitors of the TCR-Nck interaction |
ES2534336B1 (en) | 2013-10-18 | 2016-01-28 | Artax Biopharma Inc. | Chromene derivatives as inhibitors of the TCR-Nck interaction |
CN104059378B (en) * | 2014-06-27 | 2016-04-20 | 安徽大学 | A kind of six coumarin derivatives Two-photon fluorescent dye replaced and preparation method thereof |
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CN105412084B (en) * | 2015-11-20 | 2019-04-12 | 西安交通大学 | The inflammatory applications and its extracting method of sesibricin in Root of Buchtorm Libanotis |
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CH522631A (en) | 1961-08-12 | 1972-06-30 | Cassella Farbwerke Mainkur Ag | 7-hydroxy-coumarin derivs |
US3259635A (en) * | 1962-07-26 | 1966-07-05 | Cassella Farbwerke Mainkur Ag | 7-hydroxy coumarin derivative |
DE3427985A1 (en) * | 1984-07-28 | 1986-01-30 | Boehringer Mannheim Gmbh, 6800 Mannheim | NEW 2H-L-BENZOPYRAN-2-ON DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
EP0428939B1 (en) * | 1989-11-21 | 1996-01-17 | Bayer Ag | Cumarin derivatives, process for their preparation, their use and thiazolylacetic acid derivatives as intermediate |
GB9109645D0 (en) | 1991-05-03 | 1991-06-26 | Celltech Ltd | Recombinant antibodies |
WO1996031206A2 (en) * | 1995-04-07 | 1996-10-10 | Warner-Lambert Company | Flavones and coumarins as agents for the treatment of atherosclerosis |
AU735729B2 (en) | 1997-09-24 | 2001-07-12 | Orion Corporation | Bisethers of 1-oxa, aza and thianaphthalen-2-ones as phospholamban inhibitors |
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JP2004509855A (en) | 2004-04-02 |
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