ZA981432B - Method and apparatus for the formation of particles - Google Patents

Method and apparatus for the formation of particles

Info

Publication number
ZA981432B
ZA981432B ZA981432A ZA981432A ZA981432B ZA 981432 B ZA981432 B ZA 981432B ZA 981432 A ZA981432 A ZA 981432A ZA 981432 A ZA981432 A ZA 981432A ZA 981432 B ZA981432 B ZA 981432B
Authority
ZA
South Africa
Prior art keywords
suspension
solution
supercritical fluid
scf
substance
Prior art date
Application number
ZA981432A
Other languages
English (en)
Inventor
Mazen Hanna
Peter York
Original Assignee
Bradford Particle Design Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bradford Particle Design Ltd filed Critical Bradford Particle Design Ltd
Publication of ZA981432B publication Critical patent/ZA981432B/xx

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
    • B01D11/0407—Solvent extraction of solutions which are liquid with a supercritical fluid the supercritical fluid acting as solvent for the solute
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
    • B01D11/0411—Solvent extraction of solutions which are liquid with a supercritical fluid the supercritical fluid acting as solvent for the solvent and as anti-solvent for the solute, e.g. formation of particles from solutions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0488—Flow sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Glanulating (AREA)
  • Nozzles (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
ZA981432A 1997-02-21 1998-02-20 Method and apparatus for the formation of particles ZA981432B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9703673.5A GB9703673D0 (en) 1997-02-21 1997-02-21 Method and apparatus for the formation of particles

Publications (1)

Publication Number Publication Date
ZA981432B true ZA981432B (en) 1998-08-27

Family

ID=10808111

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA981432A ZA981432B (en) 1997-02-21 1998-02-20 Method and apparatus for the formation of particles

Country Status (10)

Country Link
US (2) US6440337B1 (enExample)
EP (1) EP0961651B1 (enExample)
JP (1) JP2001513012A (enExample)
AT (1) ATE266463T1 (enExample)
AU (1) AU6299898A (enExample)
CA (1) CA2278347C (enExample)
DE (1) DE69823806T2 (enExample)
GB (2) GB9703673D0 (enExample)
WO (1) WO1998036825A1 (enExample)
ZA (1) ZA981432B (enExample)

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AU6299898A (en) 1998-09-09
GB2322326B (en) 2001-12-12
DE69823806T2 (de) 2005-04-28
ATE266463T1 (de) 2004-05-15
US6440337B1 (en) 2002-08-27
US20030047824A1 (en) 2003-03-13
EP0961651A1 (en) 1999-12-08
GB9803634D0 (en) 1998-04-15
GB2322326A (en) 1998-08-26
DE69823806D1 (de) 2004-06-17
JP2001513012A (ja) 2001-08-28
CA2278347C (en) 2006-01-03
GB9703673D0 (en) 1997-04-09
EP0961651B1 (en) 2004-05-12
CA2278347A1 (en) 1998-08-27
WO1998036825A1 (en) 1998-08-27

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