ZA9811759B - Novel indole derivatives, processes for their preparation, their use and pharmaceutical compositions containing them. - Google Patents

Novel indole derivatives, processes for their preparation, their use and pharmaceutical compositions containing them.

Info

Publication number
ZA9811759B
ZA9811759B ZA9811759A ZA9811759A ZA9811759B ZA 9811759 B ZA9811759 B ZA 9811759B ZA 9811759 A ZA9811759 A ZA 9811759A ZA 9811759 A ZA9811759 A ZA 9811759A ZA 9811759 B ZA9811759 B ZA 9811759B
Authority
ZA
South Africa
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
indole derivatives
Prior art date
Application number
ZA9811759A
Other languages
English (en)
Inventor
Elizabeth Defosa
Uwe Heinelt
Otmar Klingler
Gerhard Zoller
Fahad A Al-Obeidi
D Armin Walser
Peter Wildgoose
Hans Matter
Original Assignee
Hoechst Marion Roussel De Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel De Gmbh filed Critical Hoechst Marion Roussel De Gmbh
Publication of ZA9811759B publication Critical patent/ZA9811759B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA9811759A 1997-12-24 1998-12-22 Novel indole derivatives, processes for their preparation, their use and pharmaceutical compositions containing them. ZA9811759B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97122901 1997-12-24

Publications (1)

Publication Number Publication Date
ZA9811759B true ZA9811759B (en) 1999-07-28

Family

ID=8227884

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9811759A ZA9811759B (en) 1997-12-24 1998-12-22 Novel indole derivatives, processes for their preparation, their use and pharmaceutical compositions containing them.

Country Status (29)

Country Link
US (1) US6337344B1 (tr)
EP (1) EP1042287B1 (tr)
JP (1) JP4589529B2 (tr)
KR (1) KR100608472B1 (tr)
CN (1) CN1220681C (tr)
AR (1) AR018031A1 (tr)
AT (1) ATE293599T1 (tr)
AU (1) AU743881B2 (tr)
BR (1) BR9814340B1 (tr)
CA (1) CA2316172C (tr)
CZ (1) CZ298827B6 (tr)
DE (1) DE69829879T2 (tr)
DK (1) DK1042287T3 (tr)
ES (1) ES2241194T3 (tr)
HK (1) HK1033795A1 (tr)
HU (1) HU227568B1 (tr)
ID (1) ID27044A (tr)
IL (1) IL136954A0 (tr)
MY (1) MY120064A (tr)
NO (1) NO316912B1 (tr)
NZ (1) NZ505370A (tr)
PL (1) PL195682B1 (tr)
PT (1) PT1042287E (tr)
RU (1) RU2225397C2 (tr)
SI (1) SI1042287T1 (tr)
TR (1) TR200001954T2 (tr)
TW (1) TWI241294B (tr)
WO (1) WO1999033800A1 (tr)
ZA (1) ZA9811759B (tr)

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Also Published As

Publication number Publication date
CN1220681C (zh) 2005-09-28
HUP0100723A2 (hu) 2001-08-28
NO316912B1 (no) 2004-06-21
CN1283186A (zh) 2001-02-07
CZ298827B6 (cs) 2008-02-20
WO1999033800A1 (en) 1999-07-08
BR9814340B1 (pt) 2010-07-13
PT1042287E (pt) 2005-08-31
NO20003057D0 (no) 2000-06-14
HUP0100723A3 (en) 2002-12-28
DE69829879D1 (de) 2005-05-25
KR20010033573A (ko) 2001-04-25
AU2052899A (en) 1999-07-19
SI1042287T1 (en) 2005-10-31
RU2225397C2 (ru) 2004-03-10
CA2316172C (en) 2010-02-02
JP2001527066A (ja) 2001-12-25
ES2241194T3 (es) 2005-10-16
AR018031A1 (es) 2001-10-31
PL195682B1 (pl) 2007-10-31
NO20003057L (no) 2000-08-18
AU743881B2 (en) 2002-02-07
IL136954A0 (en) 2001-06-14
CZ20002310A3 (cs) 2000-10-11
PL341400A1 (en) 2001-04-09
NZ505370A (en) 2002-06-28
DK1042287T3 (da) 2005-08-15
HU227568B1 (en) 2011-08-29
US6337344B1 (en) 2002-01-08
JP4589529B2 (ja) 2010-12-01
EP1042287A1 (en) 2000-10-11
KR100608472B1 (ko) 2006-08-09
HK1033795A1 (en) 2001-09-21
CA2316172A1 (en) 1999-07-08
TR200001954T2 (tr) 2000-12-21
DE69829879T2 (de) 2006-03-02
ATE293599T1 (de) 2005-05-15
ID27044A (id) 2001-02-22
BR9814340A (pt) 2000-10-03
EP1042287B1 (en) 2005-04-20
TWI241294B (en) 2005-10-11
MY120064A (en) 2005-08-30

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