ZA977327B - Pharmaceutical composition containing 4-oxobutanoic acids. - Google Patents

Pharmaceutical composition containing 4-oxobutanoic acids.

Info

Publication number
ZA977327B
ZA977327B ZA9707327A ZA977327A ZA977327B ZA 977327 B ZA977327 B ZA 977327B ZA 9707327 A ZA9707327 A ZA 9707327A ZA 977327 A ZA977327 A ZA 977327A ZA 977327 B ZA977327 B ZA 977327B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical composition
composition containing
oxobutanoic acids
oxobutanoic
acids
Prior art date
Application number
ZA9707327A
Other languages
English (en)
Inventor
Gerard Moinet
Micheline Kergoat
Didier Mesangeau
Liliane Doare
Philippe Maizeray
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA977327B publication Critical patent/ZA977327B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/84Unsaturated compounds containing keto groups containing six membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/16Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA9707327A 1996-08-16 1997-08-14 Pharmaceutical composition containing 4-oxobutanoic acids. ZA977327B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9610254A FR2752422B1 (fr) 1996-08-16 1996-08-16 Composition pharmaceutique contenant des acides 4-oxo-butanoiques

Publications (1)

Publication Number Publication Date
ZA977327B true ZA977327B (en) 1998-03-30

Family

ID=9495089

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9707327A ZA977327B (en) 1996-08-16 1997-08-14 Pharmaceutical composition containing 4-oxobutanoic acids.

Country Status (30)

Country Link
US (1) US6143787A (ru)
EP (1) EP0925273B1 (ru)
JP (1) JP3105545B2 (ru)
KR (1) KR100488430B1 (ru)
CN (1) CN1082370C (ru)
AR (1) AR009251A1 (ru)
AT (1) ATE208364T1 (ru)
AU (1) AU725440B2 (ru)
BR (1) BR9711315A (ru)
CA (1) CA2263348C (ru)
CY (1) CY2298B1 (ru)
CZ (1) CZ294165B6 (ru)
DE (1) DE69708130T2 (ru)
DK (1) DK0925273T3 (ru)
ES (1) ES2166098T3 (ru)
FR (1) FR2752422B1 (ru)
HK (1) HK1021728A1 (ru)
HU (1) HUP0004223A3 (ru)
ID (1) ID17875A (ru)
NO (1) NO312290B1 (ru)
PL (1) PL187371B1 (ru)
PT (1) PT925273E (ru)
RU (1) RU2175966C2 (ru)
SI (1) SI0925273T1 (ru)
SK (1) SK283055B6 (ru)
TR (1) TR199900329T2 (ru)
TW (1) TW438764B (ru)
UA (1) UA57031C2 (ru)
WO (1) WO1998007681A1 (ru)
ZA (1) ZA977327B (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04318852A (ja) * 1991-04-18 1992-11-10 Fujitsu Ltd レジスト・パターン形成方法
NZ530051A (en) 2001-06-12 2006-12-22 Wellstat Therapeutics Corp Polycyclic oxy-aromatic acid derivatives for the treatment of metabolic disorders
FR2832633B1 (fr) * 2001-11-28 2004-09-24 Lipha Composition pharmaceutique comprenant une association metformine et un acide 4-oxo-butanoique et son utilisation pour traiter le diabete
FR2832925B1 (fr) * 2001-12-03 2006-07-14 Lipha Utilisation de derives de l'acide 4-oxobutanoique dans le traitement de l'inflammation
FR2834214B1 (fr) * 2001-12-28 2004-09-24 Lipha Composition pharmaceutique comprenant un inhibiteur d'alpha-glucosidase et un acide 4-oxo-butanoique et son utilisation pour traiter le diabete
FR2834640B1 (fr) * 2002-01-11 2004-09-24 Lipha Composition pharmaceutique comprenant une glitazone et un acide 4-oxobutanoique et son utilisation pour traiter le diabete
EP1556085A4 (en) * 2002-11-01 2012-08-22 Wellstat Therapeutics Corp COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
WO2004041256A2 (en) * 2002-11-08 2004-05-21 Novo Nordisk A/S Safe chemical uncouplers for the treatment of obesity
FR2849598B1 (fr) * 2003-01-07 2006-09-22 Merck Sante Sas Utilisation d'inhibiteurs de la kynurenine-3-hydroxylase pour le traitement du diabete, par augmentation du nombre de cellules des ilots de langerhans
FR2849599B1 (fr) * 2003-01-07 2006-12-29 Merck Sante Sas Utilisation d'inhibiteurs de la kynurenine-3-hydroxylase pour le traitement du diabete
PT1633340E (pt) * 2003-04-15 2011-02-22 Wellstat Therapeutics Corp Compostos para o tratamento de distúrbios metabólicos
US20100273872A1 (en) 2007-12-03 2010-10-28 Valerie Autier Use of 4-oxobutanoic acid derivatives in the treatment of pathologies associated with immunological disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250517A (en) * 1987-10-06 1993-10-05 Hoffmann-La Roche Inc. Renin inhibiting compounds
DK523288A (da) * 1987-10-06 1989-04-07 Hoffmann La Roche Aminosyrederivater
CA1329680C (en) * 1987-11-23 1994-05-17 Harold Norris Weller, Iii N-heterocyclic alcohol derivatives
US5055466A (en) * 1987-11-23 1991-10-08 E. R. Squibb & Sons, Inc. N-morpholino derivatives and their use as anti-hypertensive agents

Also Published As

Publication number Publication date
AU725440B2 (en) 2000-10-12
NO990707D0 (no) 1999-02-15
NO990707L (no) 1999-02-15
KR20000068106A (ko) 2000-11-25
WO1998007681A1 (fr) 1998-02-26
CZ49899A3 (cs) 1999-05-12
UA57031C2 (ru) 2003-06-16
BR9711315A (pt) 1999-08-17
DE69708130T2 (de) 2002-06-20
HK1021728A1 (en) 2000-06-30
CY2298B1 (en) 2003-07-04
NO312290B1 (no) 2002-04-22
SK18099A3 (en) 2000-03-13
EP0925273A1 (fr) 1999-06-30
JP3105545B2 (ja) 2000-11-06
ES2166098T3 (es) 2002-04-01
HUP0004223A3 (en) 2001-12-28
RU2175966C2 (ru) 2001-11-20
AR009251A1 (es) 2000-04-12
PL187371B1 (pl) 2004-06-30
CN1082370C (zh) 2002-04-10
TW438764B (en) 2001-06-07
CZ294165B6 (cs) 2004-10-13
ATE208364T1 (de) 2001-11-15
TR199900329T2 (xx) 1999-04-21
AU3942297A (en) 1998-03-06
FR2752422A1 (fr) 1998-02-20
KR100488430B1 (ko) 2005-05-10
ID17875A (id) 1998-02-05
CA2263348A1 (fr) 1998-02-26
PL331645A1 (en) 1999-08-02
SI0925273T1 (en) 2002-04-30
HUP0004223A2 (hu) 2001-04-28
CA2263348C (en) 2008-05-13
CN1227538A (zh) 1999-09-01
JP2000506543A (ja) 2000-05-30
US6143787A (en) 2000-11-07
SK283055B6 (sk) 2003-02-04
DE69708130D1 (de) 2001-12-13
PT925273E (pt) 2002-04-29
DK0925273T3 (da) 2002-02-18
EP0925273B1 (fr) 2001-11-07
FR2752422B1 (fr) 1998-11-06

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