ZA9711431B - Novel compounds - Google Patents

Novel compounds

Info

Publication number
ZA9711431B
ZA9711431B ZA9711431A ZA9711431A ZA9711431B ZA 9711431 B ZA9711431 B ZA 9711431B ZA 9711431 A ZA9711431 A ZA 9711431A ZA 9711431 A ZA9711431 A ZA 9711431A ZA 9711431 B ZA9711431 B ZA 9711431B
Authority
ZA
South Africa
Prior art keywords
novel compounds
novel
compounds
Prior art date
Application number
ZA9711431A
Other languages
English (en)
Inventor
Raymond Azoulay
Graig Leigh Bentzen
Simon Floret
Robert John Ife
Lan Mong Nguyen
Eric Niesor
Hieu Trung Phan
Vinh Van Diep
Original Assignee
Symphar Sa
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symphar Sa, Smithkline Beecham Plc filed Critical Symphar Sa
Publication of ZA9711431B publication Critical patent/ZA9711431B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/58Pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA9711431A 1996-12-20 1997-12-19 Novel compounds ZA9711431B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9626615.0A GB9626615D0 (en) 1996-12-20 1996-12-20 Novel compounds

Publications (1)

Publication Number Publication Date
ZA9711431B true ZA9711431B (en) 1999-06-21

Family

ID=10804837

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9711431A ZA9711431B (en) 1996-12-20 1997-12-19 Novel compounds

Country Status (31)

Country Link
US (2) US6303784B1 (ru)
EP (1) EP0946572B1 (ru)
JP (1) JP2001506667A (ru)
KR (1) KR20000069609A (ru)
CN (1) CN1105117C (ru)
AP (1) AP9901546A0 (ru)
AR (1) AR008541A1 (ru)
AT (1) ATE255117T1 (ru)
AU (1) AU5858898A (ru)
BG (1) BG103574A (ru)
BR (1) BR9714650A (ru)
CA (1) CA2275696A1 (ru)
CO (1) CO4930276A1 (ru)
DE (1) DE69726449T2 (ru)
DZ (1) DZ2377A1 (ru)
EA (1) EA199900580A1 (ru)
GB (1) GB9626615D0 (ru)
HU (1) HUP0002171A3 (ru)
ID (1) ID22053A (ru)
IL (1) IL130334A0 (ru)
MA (1) MA24427A1 (ru)
NO (1) NO993001L (ru)
NZ (1) NZ335884A (ru)
OA (1) OA11068A (ru)
PE (1) PE46799A1 (ru)
PL (1) PL334189A1 (ru)
SK (1) SK81099A3 (ru)
TR (1) TR199901423T2 (ru)
TW (1) TW434221B (ru)
WO (1) WO1998028310A1 (ru)
ZA (1) ZA9711431B (ru)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2330552T3 (es) 2000-02-16 2009-12-11 Smithkline Beecham Plc Derivados de pirimidin-5-ona como inhibidores de ldl-pla2.
EP1531157B1 (en) * 2000-02-29 2008-03-19 Medicure International Inc. Cardioprotective phosphonates
EP1268498B1 (en) * 2000-02-29 2005-04-13 Medicure International Inc. Cardioprotective phosphonates
US20030114421A1 (en) * 2000-09-27 2003-06-19 Phan Hieu Trung Alpha-substituted beta-aminoethyl phosphonate derivatives
KR100722586B1 (ko) * 2000-09-27 2007-05-28 일렉스 프로덕츠, 인코포레이티드 α-치환된 β-아미노에틸 포스포네이트
GB0024808D0 (en) 2000-10-10 2000-11-22 Smithkline Beecham Plc Novel compounds
GB0025849D0 (en) * 2000-10-23 2000-12-06 Smithkline Beecham Plc Novel compounds
AU2003219701A1 (en) * 2002-02-11 2003-09-04 Ilex Products, Inc. Alpha-substituted heteroarylalkyl phosphonate derivatives
US7208481B2 (en) * 2002-02-19 2007-04-24 Ilex Products, Inc. Aminodiphosphonate apolipoprotein E modulators
JP4824968B2 (ja) * 2005-08-18 2011-11-30 株式会社クレハ ホスホン酸誘導体及びその酸付加塩、並びにそれを用いた農園芸用病害防除剤
WO2012076435A1 (en) 2010-12-06 2012-06-14 Glaxo Group Limited Pyrimidinone compounds for use in the treatment of diseases or conditions mediated by lp - pla2
JP2014521625A (ja) 2011-07-27 2014-08-28 グラクソ グループ リミテッド 二環式ピリミドン化合物
EP2739627A4 (en) 2011-07-27 2015-01-21 Glaxo Group Ltd 2,3-DIHYDROIMIDAZO [1,2-C] PYRIMIDIN-5 (1H) -ONE COMPOUNDS AND USE AS INHIBITORS OF LP-PLA2
BR112014004251A2 (pt) 2011-09-01 2017-03-21 Glaxo Group Ltd nova forma de cristal
RU2015135824A (ru) 2013-01-25 2017-03-03 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Бициклические соединения пиримидона в качестве ингибиторов lp-pla2
BR112015017768A2 (pt) 2013-01-25 2017-07-11 Glaxosmithkline Ip Dev Ltd compostos
EP2948452B1 (en) 2013-01-25 2017-08-09 GlaxoSmithKline Intellectual Property Development Limited 2,3-dihydroimidazol[1,2-c]pyrimidin-5(1h)-one based lipoprotein-associated phospholipase a2 (lp-pla2) inhibitors
WO2016012916A1 (en) 2014-07-22 2016-01-28 Glaxosmithkline Intellectual Property Development Limited 1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidine derivatives useful in the treatment of diseases and disorders mediated by lp-pla2
WO2016012917A1 (en) 2014-07-22 2016-01-28 Glaxosmithkline Intellectual Property Development Limited 1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidine derivatives useful in the treatment of diseases and disorders mediated by lp-pla2
MX2022005615A (es) 2019-11-09 2022-07-27 Shanghai Simr Biotechnology Co Ltd Derivado triciclico de dihidroimidazopirimidona, metodo de preparacion del mismo, composicion farmaceutica y uso del mismo.
CN115304620A (zh) 2021-05-07 2022-11-08 上海赛默罗生物科技有限公司 嘧啶酮衍生物、其制备方法、药物组合物和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH683996A5 (fr) 1992-03-05 1994-06-30 Symphar Sa Dérivés aminophosphonates substitués, leur procédé de préparation et compositions pharmaceutiques les contenant.
DE4433244A1 (de) * 1994-09-19 1996-03-28 Hoechst Ag Aminomethylphosphon- und Aminomethylphosphinsäure-Derivate und deren Verwendung zur Behandlung von degenerativen Gelenkserkrankungen
CH690264A5 (fr) 1995-06-30 2000-06-30 Symphar Sa Dérivés aminophosphonates substitués, leur procédé de préparation et leur utilisation pour la préparation de compositions pharmaceutiques.
GB9626536D0 (en) 1996-12-20 1997-02-05 Symphar Sa Novel compounds

Also Published As

Publication number Publication date
PE46799A1 (es) 1999-06-24
ATE255117T1 (de) 2003-12-15
MA24427A1 (fr) 1998-07-01
CN1105117C (zh) 2003-04-09
IL130334A0 (en) 2000-06-01
JP2001506667A (ja) 2001-05-22
US20020082423A1 (en) 2002-06-27
GB9626615D0 (en) 1997-02-05
HUP0002171A3 (en) 2002-12-28
NO993001D0 (no) 1999-06-18
HUP0002171A2 (hu) 2001-05-28
SK81099A3 (en) 1999-11-08
DE69726449T2 (de) 2004-08-26
CO4930276A1 (es) 2000-06-27
BG103574A (bg) 2000-11-30
ID22053A (id) 1999-08-26
EA199900580A1 (ru) 1999-12-29
DZ2377A1 (fr) 2002-12-28
PL334189A1 (en) 2000-02-14
EP0946572A1 (en) 1999-10-06
CA2275696A1 (en) 1998-07-02
WO1998028310A1 (en) 1998-07-02
NZ335884A (en) 2000-11-24
OA11068A (en) 2003-03-10
KR20000069609A (ko) 2000-11-25
CN1240451A (zh) 2000-01-05
TW434221B (en) 2001-05-16
AP9901546A0 (en) 1999-06-30
EP0946572B1 (en) 2003-11-26
US6303784B1 (en) 2001-10-16
AR008541A1 (es) 2000-01-19
AU5858898A (en) 1998-07-17
NO993001L (no) 1999-06-18
DE69726449D1 (en) 2004-01-08
BR9714650A (pt) 2000-10-03
TR199901423T2 (xx) 1999-10-21

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