ZA966026B - Resolution of 1-azabicyclo [2.2.2] octan-3-amine, 2 (diphenylmethyl)-N-[[2methoxy-5-(1-methylethyl) phenyl]methyl]. - Google Patents

Resolution of 1-azabicyclo [2.2.2] octan-3-amine, 2 (diphenylmethyl)-N-[[2methoxy-5-(1-methylethyl) phenyl]methyl].

Info

Publication number
ZA966026B
ZA966026B ZA9606026A ZA966026A ZA966026B ZA 966026 B ZA966026 B ZA 966026B ZA 9606026 A ZA9606026 A ZA 9606026A ZA 966026 A ZA966026 A ZA 966026A ZA 966026 B ZA966026 B ZA 966026B
Authority
ZA
South Africa
Prior art keywords
2methoxy
octan
diphenylmethyl
azabicyclo
methylethyl
Prior art date
Application number
ZA9606026A
Other languages
English (en)
Inventor
Derek L Tickner
Morgan Meltz
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA966026B publication Critical patent/ZA966026B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
ZA9606026A 1995-07-17 1996-07-16 Resolution of 1-azabicyclo [2.2.2] octan-3-amine, 2 (diphenylmethyl)-N-[[2methoxy-5-(1-methylethyl) phenyl]methyl]. ZA966026B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US119195P 1995-07-17 1995-07-17

Publications (1)

Publication Number Publication Date
ZA966026B true ZA966026B (en) 1998-01-16

Family

ID=21694832

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9606026A ZA966026B (en) 1995-07-17 1996-07-16 Resolution of 1-azabicyclo [2.2.2] octan-3-amine, 2 (diphenylmethyl)-N-[[2methoxy-5-(1-methylethyl) phenyl]methyl].

Country Status (26)

Country Link
US (1) US6008357A (da)
EP (1) EP0840735B1 (da)
JP (1) JP3043074B2 (da)
KR (1) KR100276989B1 (da)
CN (1) CN1068598C (da)
AR (1) AR002772A1 (da)
AT (1) ATE250600T1 (da)
AU (1) AU697553B2 (da)
CA (1) CA2227194C (da)
CO (1) CO4480720A1 (da)
CZ (1) CZ15098A3 (da)
DE (1) DE69630123T2 (da)
DK (1) DK0840735T3 (da)
ES (1) ES2205039T3 (da)
HK (1) HK1010195A1 (da)
HU (1) HUP9900238A3 (da)
IL (1) IL122655A0 (da)
MY (1) MY115734A (da)
NO (1) NO980211L (da)
NZ (1) NZ310539A (da)
PE (1) PE8798A1 (da)
PL (1) PL184261B1 (da)
PT (1) PT840735E (da)
RU (1) RU2136681C1 (da)
WO (1) WO1997003984A1 (da)
ZA (1) ZA966026B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6861526B2 (en) 2002-10-16 2005-03-01 Pfizer Inc. Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine
DE602005003791T2 (de) * 2004-02-02 2008-05-29 Pfizer Products Inc., Groton Verfahren zur herstellung von 1-(2s,3s)-2-benzhydril-n-(5-tert.-butyl-2-methoxybenzyl)chinuklidin-3-amin
CA2581863A1 (en) * 2004-11-10 2006-05-26 Boehringer Ingelheim Chemicals, Inc. Process of making fentanyl intermediates
US20110301159A1 (en) * 2008-12-09 2011-12-08 University Of South Florida Kinase inhibitor compounds
US20160332962A1 (en) 2015-05-13 2016-11-17 Janssen Pharmaceutica Nv (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
CN108341812A (zh) * 2017-01-23 2018-07-31 科贝源(北京)生物医药科技有限公司 一种含奎宁环化合物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990005525A1 (en) * 1988-11-23 1990-05-31 Pfizer Inc. Quinuclidine derivatives as substance p antagonists
NO168529C (no) * 1989-09-15 1992-03-04 Chiron Lab As Fremgangsmaate for fremstilling av s-(-) og r-(+)-n-(quinuclidinyl-3)-amider.
PL170513B1 (en) * 1991-05-22 1996-12-31 Pfizer Method of obtaining novel derivatives of 3-amino quinuclidine
PL171379B1 (en) * 1991-05-31 1997-04-30 Pfizer Method of obtaining novel derivatives of quinuclidine
US5604241A (en) * 1992-10-21 1997-02-18 Pfizer Inc. Substituted benzylaminoquinuclidines as substance P antagonists

Also Published As

Publication number Publication date
KR19990029058A (ko) 1999-04-15
CN1068598C (zh) 2001-07-18
CA2227194C (en) 2002-02-12
NZ310539A (en) 1998-11-25
KR100276989B1 (ko) 2001-01-15
PL324610A1 (en) 1998-06-08
JPH10511102A (ja) 1998-10-27
RU2136681C1 (ru) 1999-09-10
DE69630123D1 (en) 2003-10-30
HK1010195A1 (en) 1999-06-17
US6008357A (en) 1999-12-28
CA2227194A1 (en) 1997-02-06
EP0840735B1 (en) 2003-09-24
DK0840735T3 (da) 2004-02-09
ATE250600T1 (de) 2003-10-15
CZ15098A3 (cs) 1999-02-17
PL184261B1 (pl) 2002-09-30
HUP9900238A3 (en) 2001-08-28
DE69630123T2 (de) 2004-04-08
ES2205039T3 (es) 2004-05-01
HUP9900238A2 (hu) 1999-05-28
MX9800538A (es) 1998-05-31
PE8798A1 (es) 1998-03-02
JP3043074B2 (ja) 2000-05-22
EP0840735A1 (en) 1998-05-13
AR002772A1 (es) 1998-04-29
IL122655A0 (en) 1998-08-16
CN1190970A (zh) 1998-08-19
NO980211D0 (no) 1998-01-16
MY115734A (en) 2003-08-30
AU697553B2 (en) 1998-10-08
PT840735E (pt) 2004-02-27
CO4480720A1 (es) 1997-07-09
AU6134896A (en) 1997-02-18
WO1997003984A1 (en) 1997-02-06
NO980211L (no) 1998-03-16

Similar Documents

Publication Publication Date Title
AU3686495A (en) Benzothiophene compounds, compositions, and methods
AU7164891A (en) Rotary engine
HK1013991A1 (en) Benzothiophene compounds, intermediates, compositions, and methods
ZA968956B (en) Substituted 2,4-imidazolidinedione compounds as pharmaceutical active ingredients
AU1625197A (en) Dimethyl-(3-aryl-but-3-enyl)-amine compounds as pharmaceutically active ingredients
IL122987A0 (en) Novel 2,3-dioso-1, 2, 3, 4-tetrahydro-quinoxalinyl derivatives
AU4329396A (en) Use of 3,4-diphenylchromans
ZA965922B (en) Preparation of N-substituted 3-hydroxypyrazoles.
ZA966026B (en) Resolution of 1-azabicyclo [2.2.2] octan-3-amine, 2 (diphenylmethyl)-N-[[2methoxy-5-(1-methylethyl) phenyl]methyl].
EP0577253A3 (en) Enrichment of Quinuklidinolenantiomere.
HUP9702395A3 (en) Prokinetic oxadiazoles, process for their preparation, intermediates and pharmaceutical compositions containing the same
IL119744A0 (en) Use of 8,9-dehydroestrone
EP0639579A3 (en) Preparation of metallocenes.
AU6418396A (en) Epimers of (22RS)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-ox-4-aza-5alp ha-androst-1-ene-17beta-carboxamide
AU1972097A (en) Process for the preparation of form 1 ranitidine hydrochloride
AU2475897A (en) Process for the preparation of ((5,6-dicarboxy-3-pyridyl) methyl) ammonium halides
EP0617130A3 (en) Method for solving racemic mixtures.
AP9701149A0 (en) 2-azabicyclo {2.2.1.}heptane derivatives preparation and application thereof
EP0594481A3 (en) Medium movement articulator capable of being adjusted for free movement.
HU9403065D0 (en) Three-cylinder double operation " thermosprinter " engine
AU699753C (en) Benzothiophene compounds, intermediates, compositions and methods
AU695181B2 (en) Process for the manufacture of form 1 ranitidine hydrochloride
AU696576B2 (en) 4-amino-5-oxy-2,6,6-trimethyl-2-cycloheptene compounds
AU1442099A (en) Process for the preparation of substituted 8-azabicyclo{3.2.1}octanes
AU4579796A (en) Benzothiophene compounds, intermediates, compositions and methods