PT840735E - Resolucao de 2-(difenilmetil)-n-{¬2-metoxi-5-(1-metiletil)fenil|metil}-1-azabiciclo¬2.2.2|octan-3-amina - Google Patents

Resolucao de 2-(difenilmetil)-n-{¬2-metoxi-5-(1-metiletil)fenil|metil}-1-azabiciclo¬2.2.2|octan-3-amina

Info

Publication number
PT840735E
PT840735E PT96918801T PT96918801T PT840735E PT 840735 E PT840735 E PT 840735E PT 96918801 T PT96918801 T PT 96918801T PT 96918801 T PT96918801 T PT 96918801T PT 840735 E PT840735 E PT 840735E
Authority
PT
Portugal
Prior art keywords
methylthyl
octan
diphenylmethyl
azabicyclo
methoxy
Prior art date
Application number
PT96918801T
Other languages
English (en)
Inventor
Morgan Meltz
Derek L Tickner
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PT840735E publication Critical patent/PT840735E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
PT96918801T 1995-07-17 1996-07-04 Resolucao de 2-(difenilmetil)-n-{¬2-metoxi-5-(1-metiletil)fenil|metil}-1-azabiciclo¬2.2.2|octan-3-amina PT840735E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US119195P 1995-07-17 1995-07-17

Publications (1)

Publication Number Publication Date
PT840735E true PT840735E (pt) 2004-02-27

Family

ID=21694832

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96918801T PT840735E (pt) 1995-07-17 1996-07-04 Resolucao de 2-(difenilmetil)-n-{¬2-metoxi-5-(1-metiletil)fenil|metil}-1-azabiciclo¬2.2.2|octan-3-amina

Country Status (26)

Country Link
US (1) US6008357A (pt)
EP (1) EP0840735B1 (pt)
JP (1) JP3043074B2 (pt)
KR (1) KR100276989B1 (pt)
CN (1) CN1068598C (pt)
AR (1) AR002772A1 (pt)
AT (1) ATE250600T1 (pt)
AU (1) AU697553B2 (pt)
CA (1) CA2227194C (pt)
CO (1) CO4480720A1 (pt)
CZ (1) CZ15098A3 (pt)
DE (1) DE69630123T2 (pt)
DK (1) DK0840735T3 (pt)
ES (1) ES2205039T3 (pt)
HK (1) HK1010195A1 (pt)
HU (1) HUP9900238A3 (pt)
IL (1) IL122655A0 (pt)
MY (1) MY115734A (pt)
NO (1) NO980211L (pt)
NZ (1) NZ310539A (pt)
PE (1) PE8798A1 (pt)
PL (1) PL184261B1 (pt)
PT (1) PT840735E (pt)
RU (1) RU2136681C1 (pt)
WO (1) WO1997003984A1 (pt)
ZA (1) ZA966026B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6861526B2 (en) 2002-10-16 2005-03-01 Pfizer Inc. Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine
PL1713801T3 (pl) * 2004-02-02 2008-04-30 Pfizer Products Incorporated Sposób wytwarzania 1-(2S,3S)-2-benzhydrylo-N-(5-tert-butylo-2-metoksybenzylo)chinuklidyno-3-aminy
EP1812391A2 (en) * 2004-11-10 2007-08-01 Boehringer Ingelheim Chemicals, Inc. Process of making fentanyl intermediates
EP2376425A4 (en) * 2008-12-09 2012-12-26 Univ Florida KINASE INHIBITORS COMPOUNDS
US20160332962A1 (en) 2015-05-13 2016-11-17 Janssen Pharmaceutica Nv (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
CN108341812A (zh) * 2017-01-23 2018-07-31 科贝源(北京)生物医药科技有限公司 一种含奎宁环化合物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX18467A (es) * 1988-11-23 1993-07-01 Pfizer Agentes terapeuticos de quinuclidinas
NO168529C (no) * 1989-09-15 1992-03-04 Chiron Lab As Fremgangsmaate for fremstilling av s-(-) og r-(+)-n-(quinuclidinyl-3)-amider.
UA26401C2 (uk) * 1991-05-22 1999-08-30 Пфайзер Інк. Заміщеhі 3-аміhохіhуклідиhи
US5807867A (en) * 1991-05-31 1998-09-15 Pfizer Inc. Quinuclidine derivatives
US5604241A (en) * 1992-10-21 1997-02-18 Pfizer Inc. Substituted benzylaminoquinuclidines as substance P antagonists

Also Published As

Publication number Publication date
NZ310539A (en) 1998-11-25
PL324610A1 (en) 1998-06-08
ATE250600T1 (de) 2003-10-15
NO980211D0 (no) 1998-01-16
HUP9900238A2 (hu) 1999-05-28
WO1997003984A1 (en) 1997-02-06
CA2227194A1 (en) 1997-02-06
DE69630123D1 (en) 2003-10-30
IL122655A0 (en) 1998-08-16
DE69630123T2 (de) 2004-04-08
HUP9900238A3 (en) 2001-08-28
ES2205039T3 (es) 2004-05-01
PL184261B1 (pl) 2002-09-30
AU697553B2 (en) 1998-10-08
KR19990029058A (ko) 1999-04-15
EP0840735A1 (en) 1998-05-13
JP3043074B2 (ja) 2000-05-22
JPH10511102A (ja) 1998-10-27
MX9800538A (es) 1998-05-31
US6008357A (en) 1999-12-28
CZ15098A3 (cs) 1999-02-17
KR100276989B1 (ko) 2001-01-15
NO980211L (no) 1998-03-16
CN1068598C (zh) 2001-07-18
AU6134896A (en) 1997-02-18
DK0840735T3 (da) 2004-02-09
ZA966026B (en) 1998-01-16
RU2136681C1 (ru) 1999-09-10
CN1190970A (zh) 1998-08-19
HK1010195A1 (en) 1999-06-17
MY115734A (en) 2003-08-30
PE8798A1 (es) 1998-03-02
CO4480720A1 (es) 1997-07-09
CA2227194C (en) 2002-02-12
AR002772A1 (es) 1998-04-29
EP0840735B1 (en) 2003-09-24

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