HK1010195A1 - Resolution of 1-azabicyclo[2.2.2]octan-3-amine, 2-(diphenylmethyl)-n-[2-methoxy-5-(1-methylethyl)phenyl]methyl] - Google Patents

Resolution of 1-azabicyclo[2.2.2]octan-3-amine, 2-(diphenylmethyl)-n-[2-methoxy-5-(1-methylethyl)phenyl]methyl]

Info

Publication number
HK1010195A1
HK1010195A1 HK98111206A HK98111206A HK1010195A1 HK 1010195 A1 HK1010195 A1 HK 1010195A1 HK 98111206 A HK98111206 A HK 98111206A HK 98111206 A HK98111206 A HK 98111206A HK 1010195 A1 HK1010195 A1 HK 1010195A1
Authority
HK
Hong Kong
Prior art keywords
octan
diphenylmethyl
azabicyclo
methylethyl
methoxy
Prior art date
Application number
HK98111206A
Other languages
English (en)
Inventor
Derek L Tickner
Morgan Meltz
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of HK1010195A1 publication Critical patent/HK1010195A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
HK98111206A 1995-07-17 1998-10-13 Resolution of 1-azabicyclo[2.2.2]octan-3-amine, 2-(diphenylmethyl)-n-[2-methoxy-5-(1-methylethyl)phenyl]methyl] HK1010195A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US119195P 1995-07-17 1995-07-17
PCT/IB1996/000648 WO1997003984A1 (en) 1995-07-17 1996-07-04 Resolution of 1-azabicyclo[2.2.2]octan-3-amine, 2-(diphenylmethyl)-n-[[2-methoxy-5-(1-methylethyl)phenyl]methyl]

Publications (1)

Publication Number Publication Date
HK1010195A1 true HK1010195A1 (en) 1999-06-17

Family

ID=21694832

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98111206A HK1010195A1 (en) 1995-07-17 1998-10-13 Resolution of 1-azabicyclo[2.2.2]octan-3-amine, 2-(diphenylmethyl)-n-[2-methoxy-5-(1-methylethyl)phenyl]methyl]

Country Status (26)

Country Link
US (1) US6008357A (pt)
EP (1) EP0840735B1 (pt)
JP (1) JP3043074B2 (pt)
KR (1) KR100276989B1 (pt)
CN (1) CN1068598C (pt)
AR (1) AR002772A1 (pt)
AT (1) ATE250600T1 (pt)
AU (1) AU697553B2 (pt)
CA (1) CA2227194C (pt)
CO (1) CO4480720A1 (pt)
CZ (1) CZ15098A3 (pt)
DE (1) DE69630123T2 (pt)
DK (1) DK0840735T3 (pt)
ES (1) ES2205039T3 (pt)
HK (1) HK1010195A1 (pt)
HU (1) HUP9900238A3 (pt)
IL (1) IL122655A0 (pt)
MY (1) MY115734A (pt)
NO (1) NO980211L (pt)
NZ (1) NZ310539A (pt)
PE (1) PE8798A1 (pt)
PL (1) PL184261B1 (pt)
PT (1) PT840735E (pt)
RU (1) RU2136681C1 (pt)
WO (1) WO1997003984A1 (pt)
ZA (1) ZA966026B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6861526B2 (en) 2002-10-16 2005-03-01 Pfizer Inc. Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine
SI1713801T1 (sl) * 2004-02-02 2008-04-30 Pfizer Prod Inc Postopek priprave 1-(2S,3S)-2-benzhidril-N-(5-terc-butil-2-metoksibenzil)kinuklidin-3- amina
CA2581863A1 (en) * 2004-11-10 2006-05-26 Boehringer Ingelheim Chemicals, Inc. Process of making fentanyl intermediates
JP2012511585A (ja) * 2008-12-09 2012-05-24 ユニバーシティ オブ フロリダ リサーチ ファウンデーション，インコーポレイテッド キナーゼ阻害化合物
US20160332962A1 (en) 2015-05-13 2016-11-17 Janssen Pharmaceutica Nv (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
CN108341812A (zh) * 2017-01-23 2018-07-31 科贝源(北京)生物医药科技有限公司 一种含奎宁环化合物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990005525A1 (en) * 1988-11-23 1990-05-31 Pfizer Inc. Quinuclidine derivatives as substance p antagonists
NO168529C (no) * 1989-09-15 1992-03-04 Chiron Lab As Fremgangsmaate for fremstilling av s-(-) og r-(+)-n-(quinuclidinyl-3)-amider.
DE69232334T2 (de) * 1991-05-22 2002-11-14 Pfizer Inc., New York Substituierte 3-aminochinuclidine
DK0587723T3 (da) * 1991-05-31 1996-04-01 Pfizer Quinuclidinderivater
US5604241A (en) * 1992-10-21 1997-02-18 Pfizer Inc. Substituted benzylaminoquinuclidines as substance P antagonists

Also Published As

Publication number Publication date
HUP9900238A3 (en) 2001-08-28
ZA966026B (en) 1998-01-16
HUP9900238A2 (hu) 1999-05-28
NO980211L (no) 1998-03-16
US6008357A (en) 1999-12-28
PL184261B1 (pl) 2002-09-30
EP0840735A1 (en) 1998-05-13
WO1997003984A1 (en) 1997-02-06
NZ310539A (en) 1998-11-25
CA2227194A1 (en) 1997-02-06
AR002772A1 (es) 1998-04-29
DE69630123T2 (de) 2004-04-08
CZ15098A3 (cs) 1999-02-17
IL122655A0 (en) 1998-08-16
ATE250600T1 (de) 2003-10-15
KR100276989B1 (ko) 2001-01-15
JP3043074B2 (ja) 2000-05-22
AU697553B2 (en) 1998-10-08
RU2136681C1 (ru) 1999-09-10
MY115734A (en) 2003-08-30
CA2227194C (en) 2002-02-12
PT840735E (pt) 2004-02-27
KR19990029058A (ko) 1999-04-15
NO980211D0 (no) 1998-01-16
EP0840735B1 (en) 2003-09-24
ES2205039T3 (es) 2004-05-01
CN1190970A (zh) 1998-08-19
CO4480720A1 (es) 1997-07-09
AU6134896A (en) 1997-02-18
JPH10511102A (ja) 1998-10-27
CN1068598C (zh) 2001-07-18
DE69630123D1 (en) 2003-10-30
PE8798A1 (es) 1998-03-02
MX9800538A (es) 1998-05-31
DK0840735T3 (da) 2004-02-09
PL324610A1 (en) 1998-06-08

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20050704