ZA961419B - Human DNase I variants. - Google Patents

Human DNase I variants.

Info

Publication number
ZA961419B
ZA961419B ZA9601419A ZA961419A ZA961419B ZA 961419 B ZA961419 B ZA 961419B ZA 9601419 A ZA9601419 A ZA 9601419A ZA 961419 A ZA961419 A ZA 961419A ZA 961419 B ZA961419 B ZA 961419B
Authority
ZA
South Africa
Prior art keywords
variants
human dnase
actin
relates
resistant
Prior art date
Application number
ZA9601419A
Other languages
English (en)
Inventor
Robert A Lazarus
Steven Shak
Jana S Ulmer
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22248728&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA961419(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of ZA961419B publication Critical patent/ZA961419B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases RNAses, DNAses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/12Mucolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA9601419A 1995-02-24 1996-02-22 Human DNase I variants. ZA961419B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1995/002366 WO1996026278A1 (en) 1995-02-24 1995-02-24 HUMAN DNase I VARIANTS

Publications (1)

Publication Number Publication Date
ZA961419B true ZA961419B (en) 1997-08-22

Family

ID=22248728

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9601419A ZA961419B (en) 1995-02-24 1996-02-22 Human DNase I variants.

Country Status (22)

Country Link
EP (1) EP0811068B1 (bg)
JP (1) JPH11505408A (bg)
AT (1) ATE230027T1 (bg)
AU (1) AU720635B2 (bg)
BG (1) BG64061B1 (bg)
BR (1) BR9510323A (bg)
CA (1) CA2210871C (bg)
CZ (1) CZ288633B6 (bg)
DE (1) DE69529235T2 (bg)
DK (1) DK0811068T3 (bg)
ES (1) ES2188653T3 (bg)
HU (1) HU223272B1 (bg)
MX (1) MX9706428A (bg)
NO (1) NO326612B1 (bg)
PL (1) PL180773B1 (bg)
PT (1) PT811068E (bg)
RU (1) RU2215787C2 (bg)
SI (1) SI9520153B (bg)
SK (1) SK283850B6 (bg)
UA (2) UA66749C2 (bg)
WO (1) WO1996026278A1 (bg)
ZA (1) ZA961419B (bg)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK284191B6 (sk) * 1995-02-24 2004-10-05 Genentech, Inc. Aktín-rezistentný variant humánnej DNázy I
US6391607B1 (en) 1996-06-14 2002-05-21 Genentech, Inc. Human DNase I hyperactive variants
EP1433842B1 (en) 2002-12-18 2011-01-05 Roche Diagnostics GmbH Recombinant bovine pancreatic desoxyribonuclease I with high specific activity
DE60335602D1 (de) 2002-12-18 2011-02-17 Roche Diagnostics Gmbh Rekombinante Desoxyribonuclease I aus Rinder-Pankreas mit hoher spezifischer Aktivität
US20150010527A1 (en) * 2012-02-01 2015-01-08 Protalix Ltd. Dnase i polypeptides, polynucleotides encoding same, methods of producing dnase i and uses thereof in therapy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE176924T1 (de) * 1988-12-23 1999-03-15 Genentech Inc Verfahren zur herstellung von menschlicher dnase
US5464817A (en) * 1990-04-11 1995-11-07 Brigham And Women's Hospital Method for reducing the viscosity of pathological mucoid airway contents in the respiratory tract comprising administering actin-binding compounds with or without DNASE I

Also Published As

Publication number Publication date
SK283850B6 (sk) 2004-03-02
BR9510323A (pt) 1997-11-11
CZ267797A3 (cs) 1998-01-14
NO973876D0 (no) 1997-08-22
MX9706428A (es) 1997-11-29
UA65523C2 (en) 2004-04-15
CZ288633B6 (cs) 2001-08-15
BG64061B1 (bg) 2003-11-28
HU223272B1 (hu) 2004-04-28
ATE230027T1 (de) 2003-01-15
DE69529235D1 (de) 2003-01-30
NO326612B1 (no) 2009-01-19
SK114797A3 (en) 1998-02-04
UA66749C2 (en) 2004-06-15
PT811068E (pt) 2003-04-30
ES2188653T3 (es) 2003-07-01
DK0811068T3 (da) 2003-03-10
AU1970395A (en) 1996-09-11
SI9520153B (sl) 2004-10-31
PL180773B1 (pl) 2001-04-30
BG101846A (bg) 1998-07-31
PL321890A1 (en) 1997-12-22
EP0811068A1 (en) 1997-12-10
NO973876L (no) 1997-10-24
HUT77422A (hu) 1998-04-28
EP0811068B1 (en) 2002-12-18
SI9520153A (sl) 1998-06-30
CA2210871A1 (en) 1996-08-29
AU720635B2 (en) 2000-06-08
WO1996026278A1 (en) 1996-08-29
RU2215787C2 (ru) 2003-11-10
DE69529235T2 (de) 2003-09-04
JPH11505408A (ja) 1999-05-21
CA2210871C (en) 2009-04-07

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