DE69529235D1 - Menschliche dnase i varianten - Google Patents

Menschliche dnase i varianten

Info

Publication number
DE69529235D1
DE69529235D1 DE69529235T DE69529235T DE69529235D1 DE 69529235 D1 DE69529235 D1 DE 69529235D1 DE 69529235 T DE69529235 T DE 69529235T DE 69529235 T DE69529235 T DE 69529235T DE 69529235 D1 DE69529235 D1 DE 69529235D1
Authority
DE
Germany
Prior art keywords
variants
human dnase
actin
relates
resistant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69529235T
Other languages
English (en)
Other versions
DE69529235T2 (de
Inventor
A Lazarus
Steven Shak
S Ulmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22248728&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69529235(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DE69529235D1 publication Critical patent/DE69529235D1/de
Publication of DE69529235T2 publication Critical patent/DE69529235T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/12—Mucolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69529235T 1995-02-24 1995-02-24 Menschliche dnase i varianten Expired - Lifetime DE69529235T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1995/002366 WO1996026278A1 (en) 1995-02-24 1995-02-24 HUMAN DNase I VARIANTS

Publications (2)

Publication Number Publication Date
DE69529235D1 true DE69529235D1 (de) 2003-01-30
DE69529235T2 DE69529235T2 (de) 2003-09-04

Family

ID=22248728

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69529235T Expired - Lifetime DE69529235T2 (de) 1995-02-24 1995-02-24 Menschliche dnase i varianten

Country Status (22)

Country Link
EP (1) EP0811068B1 (de)
JP (1) JPH11505408A (de)
AT (1) ATE230027T1 (de)
AU (1) AU720635B2 (de)
BG (1) BG64061B1 (de)
BR (1) BR9510323A (de)
CA (1) CA2210871C (de)
CZ (1) CZ288633B6 (de)
DE (1) DE69529235T2 (de)
DK (1) DK0811068T3 (de)
ES (1) ES2188653T3 (de)
HU (1) HU223272B1 (de)
MX (1) MX9706428A (de)
NO (1) NO326612B1 (de)
PL (1) PL180773B1 (de)
PT (1) PT811068E (de)
RU (1) RU2215787C2 (de)
SI (1) SI9520153B (de)
SK (1) SK283850B6 (de)
UA (2) UA66749C2 (de)
WO (1) WO1996026278A1 (de)
ZA (1) ZA961419B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK284191B6 (sk) * 1995-02-24 2004-10-05 Genentech, Inc. Aktín-rezistentný variant humánnej DNázy I
US6391607B1 (en) * 1996-06-14 2002-05-21 Genentech, Inc. Human DNase I hyperactive variants
EP1433842B1 (de) 2002-12-18 2011-01-05 Roche Diagnostics GmbH Rekombinante Desoxyribonuclease I aus Rinder-Pankreas mit hoher spezifischer Aktivität
DE60335602D1 (de) 2002-12-18 2011-02-17 Roche Diagnostics Gmbh Rekombinante Desoxyribonuclease I aus Rinder-Pankreas mit hoher spezifischer Aktivität
EP2809780B1 (de) * 2012-02-01 2018-05-02 Protalix Ltd. Inhalierbare flüssige formulierungen der dnase i

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0449968B1 (de) * 1988-12-23 1999-02-24 Genentech, Inc. Verfahren zur herstellung von menschlicher dnase
US5464817A (en) * 1990-04-11 1995-11-07 Brigham And Women's Hospital Method for reducing the viscosity of pathological mucoid airway contents in the respiratory tract comprising administering actin-binding compounds with or without DNASE I

Also Published As

Publication number Publication date
EP0811068A1 (de) 1997-12-10
CZ288633B6 (cs) 2001-08-15
ZA961419B (en) 1997-08-22
EP0811068B1 (de) 2002-12-18
CA2210871C (en) 2009-04-07
DE69529235T2 (de) 2003-09-04
JPH11505408A (ja) 1999-05-21
UA65523C2 (en) 2004-04-15
BR9510323A (pt) 1997-11-11
MX9706428A (es) 1997-11-29
SK283850B6 (sk) 2004-03-02
CZ267797A3 (cs) 1998-01-14
AU1970395A (en) 1996-09-11
CA2210871A1 (en) 1996-08-29
HU223272B1 (hu) 2004-04-28
BG64061B1 (bg) 2003-11-28
PL321890A1 (en) 1997-12-22
SI9520153A (sl) 1998-06-30
WO1996026278A1 (en) 1996-08-29
BG101846A (en) 1998-07-31
RU2215787C2 (ru) 2003-11-10
UA66749C2 (en) 2004-06-15
DK0811068T3 (da) 2003-03-10
ES2188653T3 (es) 2003-07-01
NO973876D0 (no) 1997-08-22
NO326612B1 (no) 2009-01-19
HUT77422A (hu) 1998-04-28
SK114797A3 (en) 1998-02-04
AU720635B2 (en) 2000-06-08
SI9520153B (sl) 2004-10-31
PT811068E (pt) 2003-04-30
NO973876L (no) 1997-10-24
PL180773B1 (pl) 2001-04-30
ATE230027T1 (de) 2003-01-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition