UA66749C2 - Actin-resistant variants of human dnase i, isolated nucleic acid, a method for treatment of patients suffering from pulmonary diseases - Google Patents

Actin-resistant variants of human dnase i, isolated nucleic acid, a method for treatment of patients suffering from pulmonary diseases

Info

Publication number
UA66749C2
UA66749C2 UA97084355A UA97084355A UA66749C2 UA 66749 C2 UA66749 C2 UA 66749C2 UA 97084355 A UA97084355 A UA 97084355A UA 97084355 A UA97084355 A UA 97084355A UA 66749 C2 UA66749 C2 UA 66749C2
Authority
UA
Ukraine
Prior art keywords
actin
nucleic acid
human dnase
treatment
resistant variants
Prior art date
Application number
UA97084355A
Other languages
English (en)
Inventor
Robert A Lazarus
Jana S Ulmer
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22248728&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA66749(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of UA66749C2 publication Critical patent/UA66749C2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/12—Mucolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
UA97084355A 1995-02-24 1995-02-24 Actin-resistant variants of human dnase i, isolated nucleic acid, a method for treatment of patients suffering from pulmonary diseases UA66749C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1995/002366 WO1996026278A1 (en) 1995-02-24 1995-02-24 HUMAN DNase I VARIANTS

Publications (1)

Publication Number Publication Date
UA66749C2 true UA66749C2 (en) 2004-06-15

Family

ID=22248728

Family Applications (2)

Application Number Title Priority Date Filing Date
UA97084355A UA66749C2 (en) 1995-02-24 1995-02-24 Actin-resistant variants of human dnase i, isolated nucleic acid, a method for treatment of patients suffering from pulmonary diseases
UA97084356A UA65523C2 (en) 1995-02-24 1996-02-21 Actin-resistant variant of human dnase i, isolated nucleic acid, a method for the treatment of patients suffering of pulmonary diseases, a pharmaceuticakl composition

Family Applications After (1)

Application Number Title Priority Date Filing Date
UA97084356A UA65523C2 (en) 1995-02-24 1996-02-21 Actin-resistant variant of human dnase i, isolated nucleic acid, a method for the treatment of patients suffering of pulmonary diseases, a pharmaceuticakl composition

Country Status (22)

Country Link
EP (1) EP0811068B1 (de)
JP (1) JPH11505408A (de)
AT (1) ATE230027T1 (de)
AU (1) AU720635B2 (de)
BG (1) BG64061B1 (de)
BR (1) BR9510323A (de)
CA (1) CA2210871C (de)
CZ (1) CZ288633B6 (de)
DE (1) DE69529235T2 (de)
DK (1) DK0811068T3 (de)
ES (1) ES2188653T3 (de)
HU (1) HU223272B1 (de)
MX (1) MX9706428A (de)
NO (1) NO326612B1 (de)
PL (1) PL180773B1 (de)
PT (1) PT811068E (de)
RU (1) RU2215787C2 (de)
SI (1) SI9520153B (de)
SK (1) SK283850B6 (de)
UA (2) UA66749C2 (de)
WO (1) WO1996026278A1 (de)
ZA (1) ZA961419B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK284191B6 (sk) * 1995-02-24 2004-10-05 Genentech, Inc. Aktín-rezistentný variant humánnej DNázy I
US6391607B1 (en) 1996-06-14 2002-05-21 Genentech, Inc. Human DNase I hyperactive variants
US7118901B2 (en) 2002-12-18 2006-10-10 Roche Diagnostics Operations, Inc. Recombinant bovine pancreatic desoxyribonuclease I with high specific activity
EP1433842B1 (de) 2002-12-18 2011-01-05 Roche Diagnostics GmbH Rekombinante Desoxyribonuclease I aus Rinder-Pankreas mit hoher spezifischer Aktivität
US9603906B2 (en) 2012-02-01 2017-03-28 Protalix Ltd. Inhalable liquid formulations of DNase I

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE358176T1 (de) * 1988-12-23 2007-04-15 Genentech Inc Menschliche dnase
US5464817A (en) * 1990-04-11 1995-11-07 Brigham And Women's Hospital Method for reducing the viscosity of pathological mucoid airway contents in the respiratory tract comprising administering actin-binding compounds with or without DNASE I

Also Published As

Publication number Publication date
SK114797A3 (en) 1998-02-04
SK283850B6 (sk) 2004-03-02
CZ288633B6 (cs) 2001-08-15
NO326612B1 (no) 2009-01-19
PT811068E (pt) 2003-04-30
ZA961419B (en) 1997-08-22
HUT77422A (hu) 1998-04-28
AU720635B2 (en) 2000-06-08
WO1996026278A1 (en) 1996-08-29
AU1970395A (en) 1996-09-11
BG101846A (en) 1998-07-31
ES2188653T3 (es) 2003-07-01
BG64061B1 (bg) 2003-11-28
CA2210871C (en) 2009-04-07
ATE230027T1 (de) 2003-01-15
RU2215787C2 (ru) 2003-11-10
JPH11505408A (ja) 1999-05-21
BR9510323A (pt) 1997-11-11
SI9520153A (sl) 1998-06-30
DE69529235D1 (de) 2003-01-30
CZ267797A3 (cs) 1998-01-14
UA65523C2 (en) 2004-04-15
EP0811068B1 (de) 2002-12-18
EP0811068A1 (de) 1997-12-10
NO973876L (no) 1997-10-24
PL321890A1 (en) 1997-12-22
MX9706428A (es) 1997-11-29
NO973876D0 (no) 1997-08-22
SI9520153B (sl) 2004-10-31
HU223272B1 (hu) 2004-04-28
DE69529235T2 (de) 2003-09-04
CA2210871A1 (en) 1996-08-29
PL180773B1 (pl) 2001-04-30
DK0811068T3 (da) 2003-03-10

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