ZA9610711B - Selective alkylations of cyclodextrins leading to derivatives which hae a rigidly extended cavity - Google Patents

Selective alkylations of cyclodextrins leading to derivatives which hae a rigidly extended cavity

Info

Publication number
ZA9610711B
ZA9610711B ZA9610711A ZA9610711A ZA9610711B ZA 9610711 B ZA9610711 B ZA 9610711B ZA 9610711 A ZA9610711 A ZA 9610711A ZA 9610711 A ZA9610711 A ZA 9610711A ZA 9610711 B ZA9610711 B ZA 9610711B
Authority
ZA
South Africa
Prior art keywords
cyclodextrins
hae
derivatives
leading
extended cavity
Prior art date
Application number
ZA9610711A
Other languages
English (en)
Inventor
Josef Pitha
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of ZA9610711B publication Critical patent/ZA9610711B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ZA9610711A 1995-12-19 1996-12-19 Selective alkylations of cyclodextrins leading to derivatives which hae a rigidly extended cavity ZA9610711B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/575,075 US5681828A (en) 1995-12-19 1995-12-19 Selective alkylations of cyclodextrins leading to derivatives which have a rigidly extended cavity

Publications (1)

Publication Number Publication Date
ZA9610711B true ZA9610711B (en) 1997-06-27

Family

ID=24298829

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9610711A ZA9610711B (en) 1995-12-19 1996-12-19 Selective alkylations of cyclodextrins leading to derivatives which hae a rigidly extended cavity

Country Status (10)

Country Link
US (1) US5681828A (xx)
EP (1) EP0868438B1 (xx)
JP (3) JP3476201B2 (xx)
AT (1) ATE290550T1 (xx)
AU (1) AU1565997A (xx)
CA (1) CA2240413C (xx)
DE (1) DE69634446T2 (xx)
ES (1) ES2238703T3 (xx)
WO (1) WO1997022630A1 (xx)
ZA (1) ZA9610711B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001821A (en) * 1995-12-19 1999-12-14 Pitha; Josef Dioxane-substituted cyclodextrin macromolecules and inclusion complexes
DE19930553A1 (de) * 1999-07-02 2001-01-11 Wacker Chemie Gmbh Verfahren zur Herstellung von alkylierten Cyclodextrin-Derivaten
JP2006516642A (ja) * 2003-02-03 2006-07-06 シャイア ラボラトリーズ，インコーポレイテッド 薬物製剤およびメチル化シクロデキストリン結晶を用いた送達
KR100785913B1 (ko) * 2006-11-29 2007-12-17 한국과학기술연구원 경화된 β-사이클로덱스트린 중합체 분말과 그의 제조방법
JP2009040873A (ja) * 2007-08-08 2009-02-26 Lintec Corp 部分アシル化シクロデキストリンの製造方法および部分アシル化ロタキサンの製造方法
EP2923702A1 (en) * 2014-03-28 2015-09-30 Universite De Liege Composition of cyclodextrin with budesonide derivatives for treatment and prevention of pulmonary inflammatory disease
CN112646058A (zh) * 2019-10-11 2021-04-13 南京大学 一种两亲性多孔环糊精聚合物
CN112661874B (zh) * 2020-12-30 2022-01-07 曲阜市天利药用辅料有限公司 6-位羟丙基取代β-环糊精功能药辅助剂及其制备方法
US20220332924A1 (en) * 2021-04-09 2022-10-20 Qatar Foundation For Education, Science And Community Development Cyclodextrin-derived polymer nanoparticles for adsorption and synthesis thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8506792D0 (en) * 1985-03-15 1985-04-17 Janssen Pharmaceutica Nv Derivatives of y-cyclodextrin
JPS6259601A (ja) * 1985-09-09 1987-03-16 Nippon Shokuhin Kako Kk エ−テル化サイクロデキストリンの製造方法
DE4333598A1 (de) * 1993-10-01 1995-04-06 Consortium Elektrochem Ind Verfahren zur Herstellung von alkylierten Cyclodextrin-Derivaten, nach dem Verfahren herstellbare methylierte Cyclodextrin-Derivate und die Verwendung der Produkte

Also Published As

Publication number Publication date
EP0868438A1 (en) 1998-10-07
JP2000502381A (ja) 2000-02-29
WO1997022630A1 (en) 1997-06-26
US5681828A (en) 1997-10-28
DE69634446T2 (de) 2006-04-13
JP3476201B2 (ja) 2003-12-10
ES2238703T3 (es) 2005-09-01
JP2003342302A (ja) 2003-12-03
EP0868438A4 (en) 2001-02-07
ATE290550T1 (de) 2005-03-15
EP0868438B1 (en) 2005-03-09
JP2003201303A (ja) 2003-07-18
AU1565997A (en) 1997-07-14
CA2240413C (en) 2008-09-23
CA2240413A1 (en) 1997-06-26
JP4056437B2 (ja) 2008-03-05
DE69634446D1 (de) 2005-04-14

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