ZA948619B - Fungal protease - Google Patents

Fungal protease

Info

Publication number
ZA948619B
ZA948619B ZA948619A ZA948619A ZA948619B ZA 948619 B ZA948619 B ZA 948619B ZA 948619 A ZA948619 A ZA 948619A ZA 948619 A ZA948619 A ZA 948619A ZA 948619 B ZA948619 B ZA 948619B
Authority
ZA
South Africa
Prior art keywords
aspergillus
protease
preparation
mutant strain
aspartic
Prior art date
Application number
ZA948619A
Other languages
English (en)
Inventor
Frank Buxton
Gabor Jarai
Jacob Visser
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of ZA948619B publication Critical patent/ZA948619B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/62—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from Aspergillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA948619A 1993-11-03 1994-11-02 Fungal protease ZA948619B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93810764 1993-11-03

Publications (1)

Publication Number Publication Date
ZA948619B true ZA948619B (en) 1995-06-27

Family

ID=8215057

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA948619A ZA948619B (en) 1993-11-03 1994-11-02 Fungal protease

Country Status (18)

Country Link
US (2) US5674728A (fr)
EP (1) EP0655497B1 (fr)
JP (1) JP3727678B2 (fr)
KR (1) KR100378507B1 (fr)
AT (1) ATE235556T1 (fr)
AU (1) AU688379B2 (fr)
CA (1) CA2134863C (fr)
CY (1) CY2471B1 (fr)
DE (1) DE69432336T2 (fr)
DK (1) DK0655497T3 (fr)
ES (1) ES2196019T3 (fr)
FI (1) FI119060B (fr)
HU (1) HU220360B (fr)
IL (2) IL168245A (fr)
NO (1) NO315330B1 (fr)
NZ (1) NZ264839A (fr)
PT (1) PT655497E (fr)
ZA (1) ZA948619B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0865485A1 (fr) * 1995-12-07 1998-09-23 Novo Nordisk A/S Inactivation selective d'activites enzymatiques
CN1160465C (zh) * 1995-12-15 2004-08-04 诺沃奇梅兹有限公司 其中areA、pepC和/或pepE基因已被灭活的真菌
JP2000511429A (ja) * 1996-06-05 2000-09-05 ギスト ブロカデス ベスローテン フェンノートシャップ 真菌メタロプロテアーゼ遺伝子
ES2256895T3 (es) * 1996-09-19 2006-07-16 Novozymes A/S Celulas huesped y metodos de produccion de proteinas.
AU2006202723B2 (en) * 2001-02-23 2008-06-26 Dsm Ip Assets B.V. Novel genes encoding novel proteolytic enzymes
NZ537401A (en) * 2001-02-23 2006-08-31 Dsm Ip Assets B Proteases from Aspergillus niger
KR100880087B1 (ko) * 2001-02-23 2009-01-23 디에스엠 아이피 어셋츠 비.브이. 신규 단백질 분해효소를 암호화하는 신규 유전자
US20090253173A1 (en) * 2008-04-08 2009-10-08 Danisco Us Inc., Genencor Division Filamentous fungi with inactivated protease genes for altered protein production
FI121712B (fi) * 2009-04-30 2011-03-15 Ab Enzymes Oy Uusi sieniperäinen proteaasi ja sen käyttö
JP6245528B2 (ja) 2012-01-05 2017-12-13 グリコス・フィンランド・オーワイＧｌｙｋｏｓ Ｆｉｎｌａｎｄ Ｏｙ プロテアーゼ欠損糸状菌細胞及びその使用方法
WO2013174927A1 (fr) 2012-05-23 2013-11-28 Novartis International Pharmaceutical Limited Production de glycoprotéines fucosylées
CN105980552A (zh) 2013-07-10 2016-09-28 诺华股份有限公司 多种蛋白酶缺陷的丝状真菌细胞及其使用方法
SG11201700446XA (en) 2014-07-21 2017-02-27 Glykos Finland Oy Production of glycoproteins with mammalian-like n-glycans in filamentous fungi
CN106222096B (zh) * 2016-08-18 2018-02-23 滨州学院 一株塔宾曲霉菌ct1及其在盐碱地解磷方面的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8415186D0 (en) * 1984-06-14 1984-07-18 Ciba Geigy Ag Polypeptides
US4885249A (en) * 1984-12-05 1989-12-05 Allelix, Inc. Aspergillus niger transformation system
GB8521496D0 (en) * 1985-08-29 1985-10-02 Ciba Geigy Ag Repressible yeast promoters
GB8702475D0 (en) * 1987-02-04 1987-03-11 Ciba Geigy Ag Expression system
AU1572588A (en) * 1987-03-12 1988-10-10 Genex Corp. Production of bioadhesive precursor protein analogs by genetically-engineered organisms
US4871824A (en) * 1987-03-13 1989-10-03 Minnesota Mining And Manufacturing Company Variably crosslinked polymeric supports
US5252726A (en) * 1987-09-04 1993-10-12 Novo Nordisk A/S Promoters for use in aspergillus
CA1333777C (fr) * 1988-07-01 1995-01-03 Randy M. Berka Champignons filamenteux deficients en proteinase aspartique
EP0353188B2 (fr) * 1988-07-28 2002-03-06 Novartis AG Système d'expression
EP0421919A3 (en) * 1989-09-02 1992-04-15 Ciba-Geigy Ag Polygalacturonase encoding fungal expression system
NZ236434A (en) * 1990-01-29 1992-08-26 Ciba Geigy Ag Dna molecules comprising the a niger pyruvate kinase transcription promoter, vectors containing it and their use in transforming host cells
JPH06506117A (ja) * 1991-04-01 1994-07-14 メルク　エンド　カンパニー　インコーポレーテッド ピキア（Ｐｉｃｈｉａ）蛋白質分解活性に影響する遺伝子およびその使用
DK47493D0 (da) * 1993-04-27 1993-04-27 Novo Nordisk As Fremgangsmaade til fremstilling af ost

Also Published As

Publication number Publication date
CA2134863C (fr) 2008-12-30
IL168245A (en) 2009-12-24
NO315330B1 (no) 2003-08-18
DE69432336T2 (de) 2003-12-04
HU220360B (hu) 2001-12-28
PT655497E (pt) 2003-07-31
FI119060B (fi) 2008-07-15
NO944181D0 (no) 1994-11-02
HU9403136D0 (en) 1994-12-28
IL111482A (en) 2005-08-31
JP3727678B2 (ja) 2005-12-14
KR100378507B1 (ko) 2003-09-19
DK0655497T3 (da) 2003-07-21
JPH07213286A (ja) 1995-08-15
NZ264839A (en) 1996-03-26
EP0655497B1 (fr) 2003-03-26
ATE235556T1 (de) 2003-04-15
AU688379B2 (en) 1998-03-12
DE69432336D1 (de) 2003-04-30
HUT69954A (en) 1995-09-28
FI945163A0 (fi) 1994-11-02
US5674728A (en) 1997-10-07
FI945163A (fi) 1995-05-04
KR950014309A (ko) 1995-06-15
NO944181L (no) 1995-05-04
IL111482A0 (en) 1995-01-24
ES2196019T3 (es) 2003-12-16
AU7751494A (en) 1995-05-18
EP0655497A2 (fr) 1995-05-31
CY2471B1 (en) 2005-06-03
US5756338A (en) 1998-05-26
CA2134863A1 (fr) 1995-05-04
EP0655497A3 (fr) 1997-05-07

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