ZA938821B - 15-deoxyspergualin analogs their method of preparation and their use in therapeutics - Google Patents

15-deoxyspergualin analogs their method of preparation and their use in therapeutics

Info

Publication number
ZA938821B
ZA938821B ZA938821A ZA938821A ZA938821B ZA 938821 B ZA938821 B ZA 938821B ZA 938821 A ZA938821 A ZA 938821A ZA 938821 A ZA938821 A ZA 938821A ZA 938821 B ZA938821 B ZA 938821B
Authority
ZA
South Africa
Prior art keywords
therapeutics
preparation
deoxyspergualin
analogs
compounds
Prior art date
Application number
ZA938821A
Other languages
English (en)
Inventor
Patrice Renaut
Luc Lebreton
Patrick Dutartre
Philippe Derrepas
Soth Samreth
Original Assignee
Fournier Ind & Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fournier Ind & Sante filed Critical Fournier Ind & Sante
Publication of ZA938821B publication Critical patent/ZA938821B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Soil Conditioners And Soil-Stabilizing Materials (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
ZA938821A 1992-12-02 1993-11-25 15-deoxyspergualin analogs their method of preparation and their use in therapeutics ZA938821B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9214517A FR2698628B1 (fr) 1992-12-02 1992-12-02 Analogues de 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.

Publications (1)

Publication Number Publication Date
ZA938821B true ZA938821B (en) 1994-06-30

Family

ID=9436147

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA938821A ZA938821B (en) 1992-12-02 1993-11-25 15-deoxyspergualin analogs their method of preparation and their use in therapeutics

Country Status (24)

Country Link
US (1) US5476870A (cs)
EP (1) EP0600762B1 (cs)
JP (1) JP2945261B2 (cs)
KR (1) KR100187328B1 (cs)
CN (1) CN1045431C (cs)
AT (1) ATE140215T1 (cs)
AU (1) AU664124B2 (cs)
CA (1) CA2110437C (cs)
CZ (1) CZ284958B6 (cs)
DE (1) DE69303583T2 (cs)
DK (1) DK0600762T3 (cs)
ES (1) ES2092263T3 (cs)
FI (1) FI112211B (cs)
FR (1) FR2698628B1 (cs)
GR (1) GR3021269T3 (cs)
HK (1) HK1000467A1 (cs)
HU (1) HU218908B (cs)
NO (1) NO180483C (cs)
NZ (1) NZ250330A (cs)
RU (1) RU2114823C1 (cs)
SK (1) SK280286B6 (cs)
TW (1) TW311132B (cs)
UA (1) UA39920C2 (cs)
ZA (1) ZA938821B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2125714T3 (es) * 1995-02-10 1999-03-01 Fournier Ind & Sante Compuesto perteneciente a la familia de los analogos de la 15-deoxiespergualina.
FR2734263B1 (fr) * 1995-05-17 1997-06-20 Fournier Ind & Sante Analogues de la 15-deoxyspergualine, leur procede de preparation et leur utilisation en therapeutique
DE19728436A1 (de) * 1997-07-03 1999-01-07 Niels Franke Niedrigdosierte 15-Desoxyspergualin-Präparate
CN1330675A (zh) * 1998-08-28 2002-01-09 格莱风科学公司 精确长度的聚酰胺链、其制备方法和其与蛋白质的缀合物
DE19923961A1 (de) * 1999-05-25 2000-11-30 Euro Nippon Kayaku Gmbh Verwendung von 15-Deoxyspergualin zur Behandlung von hyperreaktiven entzündlichen Erkrankungen und Autoimmunerkrankungen
CN102940891B (zh) 2004-05-05 2016-02-24 赛伦斯治疗有限公司 脂质、脂质复合物及其应用
SG158175A1 (en) 2004-12-27 2010-01-29 Silence Therapeutics Ag Lipid complexes coated with peg and their use
US8350077B2 (en) 2008-12-24 2013-01-08 Vertex Closed Joint Stock Company Amides of creatine, method of their preparation, and remedy possessing a neuroprotective activity
RU2428414C2 (ru) 2009-11-03 2011-09-10 Закрытое Акционерное Общество "Вертекс" Способ получения амидов креатина
FR2963238B1 (fr) * 2010-07-29 2012-12-28 Fournier Lab Sa Derives de 15-desoxyspergualine pour le traitement et/ou la prevention des maladies inflammatoires oculaires
CN103037857B (zh) * 2010-07-29 2016-02-10 实验室富尼耶公司 用于治疗/预防眼部炎性疾病的化合物
KR101695730B1 (ko) 2015-03-10 2017-01-12 하경훈 마늘꼭지 절단기의 절단장치
FR3050455B1 (fr) * 2016-04-26 2019-06-14 Temisis Derives amides des acides polycafeoylquiniques, procede de preparation et utilisations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5942356A (ja) * 1982-09-02 1984-03-08 Microbial Chem Res Found スパガリン関連化合物およびその製造法
ES2039213T3 (es) * 1986-04-04 1993-09-16 Microbial Chemistry Research Foundation Procedimiento para producir nuevos compuestos relacionados con espergualina.
US5061787A (en) * 1988-06-24 1991-10-29 Nippon Kayaku Kabushiki Kaisha Novel spergualin-related compounds and compositions

Also Published As

Publication number Publication date
FR2698628B1 (fr) 1995-02-17
EP0600762B1 (fr) 1996-07-10
HU9303406D0 (en) 1994-03-28
HU218908B (hu) 2000-12-28
HK1000467A1 (en) 1998-03-27
NO180483B (no) 1997-01-20
US5476870A (en) 1995-12-19
CN1045431C (zh) 1999-10-06
SK135793A3 (en) 1994-06-08
JPH06293728A (ja) 1994-10-21
NO934338D0 (no) 1993-11-30
NO180483C (no) 1997-04-30
GR3021269T3 (en) 1997-01-31
JP2945261B2 (ja) 1999-09-06
DK0600762T3 (da) 1996-11-11
FI935318A0 (fi) 1993-11-29
EP0600762A1 (fr) 1994-06-08
HUT65782A (en) 1994-07-28
NO934338L (no) 1994-06-03
KR100187328B1 (ko) 1999-05-15
CA2110437C (en) 1999-04-13
AU5188393A (en) 1994-06-16
CZ284958B6 (cs) 1999-04-14
FR2698628A1 (fr) 1994-06-03
ES2092263T3 (es) 1996-11-16
TW311132B (cs) 1997-07-21
NZ250330A (en) 1995-06-27
RU2114823C1 (ru) 1998-07-10
UA39920C2 (uk) 2001-07-16
SK280286B6 (sk) 1999-11-08
FI112211B (fi) 2003-11-14
FI935318A (fi) 1994-06-03
CN1095709A (zh) 1994-11-30
CA2110437A1 (en) 1994-06-03
ATE140215T1 (de) 1996-07-15
KR940014435A (ko) 1994-07-18
DE69303583T2 (de) 1996-11-21
DE69303583D1 (de) 1996-08-14
AU664124B2 (en) 1995-11-02
CZ262293A3 (en) 1994-06-15

Similar Documents

Publication Publication Date Title
ZA938821B (en) 15-deoxyspergualin analogs their method of preparation and their use in therapeutics
GR3020961T3 (en) Endothelin antagonist
ES8607218A1 (es) Un procedimiento para preparar compuestos de amidina
RU93053038A (ru) Аналоги 15-деоксипергуалина, способ их получения и фармацевтическая композиция на их основе и промежуточные соединения синтеза
DE69002474D1 (en) Carboxyalkyl-ether von 2-amino-7-hydroxytetralin.
HU9301388D0 (en) Method for producing hydroxy-ethylene-isoster type compounds of hiv-protease inhibiting effect containing dithiolamine-glycine
CA2143216A1 (en) 15-Deoxyspergualin Analogs, Their Method of Preparation and Their Use in Therapeutics
HU9202103D0 (en) Method for producing inosite-phosphate analogues and pharmaceutical preparatives containing these compounds
GR3033993T3 (en) N-benzylpiperazinderivatives, process for their preparation and pharmaceutical compositions containing them.
EP0139590A3 (en) 4-alkyl-2-hydroxy-3-methyl-2-phenyl-morpholine derivatives, process for their preparation and their therapeutical use
GR3021727T3 (en) 5-Amine substituted adenosine analogs as immunosuppressants
IL103855A0 (en) 5,6-dihydro-dibenz(b,e)azepin-6,11-dione-11-oximes,their preparation and pharmaceutical compositions containing them
HUT63394A (en) Alpha-aryl-alpha-hydroxi-beta-imidazolinyl-propionic acid amide
FI924769A0 (fi) Foerfarande foer framstaellning av substituerade indoler
GR3006223T3 (cs)
EP0471383A3 (en) Use of 5'-vinylhalo-aristeromycin/adenosine analogs as immunosuppressants
GR3024391T3 (en) Cyclised analogs of metabolites of fatty acids, process for their preparation and pharmaceutical compositions containing them.