ZA9339B - 4,13-dioxabicyclo(8.2.1)tridecenone derivatives, process and intermediates for the preparation thereof and pharmaceuticals containing these compounds - Google Patents

4,13-dioxabicyclo(8.2.1)tridecenone derivatives, process and intermediates for the preparation thereof and pharmaceuticals containing these compounds

Info

Publication number
ZA9339B
ZA9339B ZA9339A ZA9339A ZA9339B ZA 9339 B ZA9339 B ZA 9339B ZA 9339 A ZA9339 A ZA 9339A ZA 9339 A ZA9339 A ZA 9339A ZA 9339 B ZA9339 B ZA 9339B
Authority
ZA
South Africa
Prior art keywords
derivatives
preparation
tridecenone
dioxabicyclo
intermediates
Prior art date
Application number
ZA9339A
Other languages
English (en)
Inventor
Dagmar Holtje
Ulf Preuschoff
Christian Eeckhout
Original Assignee
Kali Chemie Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma Gmbh filed Critical Kali Chemie Pharma Gmbh
Publication of ZA9339B publication Critical patent/ZA9339B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA9339A 1992-01-07 1993-01-05 4,13-dioxabicyclo(8.2.1)tridecenone derivatives, process and intermediates for the preparation thereof and pharmaceuticals containing these compounds ZA9339B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4200145A DE4200145A1 (de) 1992-01-07 1992-01-07 7,10-epoxy-oxacyclododecan-derivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ZA9339B true ZA9339B (en) 1993-08-05

Family

ID=6449136

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9339A ZA9339B (en) 1992-01-07 1993-01-05 4,13-dioxabicyclo(8.2.1)tridecenone derivatives, process and intermediates for the preparation thereof and pharmaceuticals containing these compounds

Country Status (27)

Country Link
US (1) US5418224A (forum.php)
EP (1) EP0550895B1 (forum.php)
JP (1) JP3300084B2 (forum.php)
KR (1) KR100273937B1 (forum.php)
CN (1) CN1033646C (forum.php)
AT (1) ATE155478T1 (forum.php)
AU (1) AU667699B2 (forum.php)
CA (1) CA2086811C (forum.php)
CZ (1) CZ281773B6 (forum.php)
DE (2) DE4200145A1 (forum.php)
DK (1) DK0550895T3 (forum.php)
DZ (1) DZ1652A1 (forum.php)
ES (1) ES2104808T3 (forum.php)
FI (1) FI106862B (forum.php)
GR (1) GR3024859T3 (forum.php)
HU (2) HU212272B (forum.php)
IL (1) IL104158A (forum.php)
LT (1) LT3015B (forum.php)
LV (1) LV10458B (forum.php)
MX (1) MX9300045A (forum.php)
NO (1) NO179586C (forum.php)
PH (1) PH30098A (forum.php)
RU (1) RU2107070C1 (forum.php)
SK (1) SK279251B6 (forum.php)
TW (1) TW238308B (forum.php)
UA (1) UA29393C2 (forum.php)
ZA (1) ZA9339B (forum.php)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69637097T2 (de) * 1995-10-13 2007-09-20 Neurosearch A/S 8-Azabicyclo(3.2.1)Oct-2-en-Derivate, deren Herstellung und Anwendung
US6077943A (en) * 1996-03-01 2000-06-20 Takeda Chemical Industries, Ltd. Method of producing erythromycin derivative
CA2247929A1 (en) * 1996-03-01 1997-09-04 Miichiro Arita Processes for the preparation of erythromycin derivatives
DE19644195A1 (de) * 1996-10-24 1998-04-30 Solvay Pharm Gmbh 10,13,15-Trioxatricyclo[9.2.1.1.·9·.·6·]-pentadecanon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US6165985A (en) * 1998-02-13 2000-12-26 Solvay Pharmaceuticals Gmbh 11-acetyl-12,13-dioxabicyclo[8.2.1]-tridecenone derivatives, processes for their preparation and pharmaceutical compositions comprising them
DE19805822B4 (de) * 1998-02-13 2009-02-05 Solvay Pharmaceuticals Gmbh 11-Acetyl-12,13-dioxabicyclo[8.2.1]tridecenon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
HRP980496B1 (en) * 1998-09-10 2007-03-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. New thilozine hydroxy derivatives and a process for the preparation thereof
KR20040066188A (ko) * 2000-08-17 2004-07-23 샤단호칭키타사토겐큐쇼 신규 슈도에리쓰로마이신 유도체
AU2001282577B2 (en) * 2000-09-01 2005-04-07 Chugai Seiyaku Kabushiki Kaisha Process for producing erythromycin derivative
EP1392679B1 (de) * 2001-05-10 2005-11-02 Solvay Pharmaceuticals GmbH Neue 1-amidomethylcarbonyl-piperidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US20040067896A1 (en) * 2002-07-25 2004-04-08 The Kitasato Institute Novel pseudoerythromycin derivatives
JP4928261B2 (ja) 2003-06-18 2012-05-09 トランザイム・ファーマ・インコーポレイテッド モチリン受容体の大環状拮抗薬
US7582611B2 (en) * 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
WO2007067281A2 (en) * 2005-12-08 2007-06-14 Pfizer, Inc. Method for demethylating the 3'-dimethylamino group of erythromycin compounds
US9133235B2 (en) 2006-09-11 2015-09-15 Ocera Therapeutics, Inc. Macrocyclic antagonists of the motilin receptor for treatment of gastrointestinal dysmotility disorders
ES2401467T3 (es) * 2006-12-05 2013-04-19 Bristol-Myers Squibb Company Polimorfos de motilida
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
WO2014156339A1 (ja) * 2013-03-25 2014-10-02 ゼリア新薬工業株式会社 食後期の胃運動亢進剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725385A (en) 1970-11-02 1973-04-03 Abbott Lab Process for the demethylation of 3-amino macrolides
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
CA1321581C (en) * 1987-05-26 1993-08-24 Herbert A. Kirst Ring-contracted macrolides
US4920102A (en) 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders

Also Published As

Publication number Publication date
MX9300045A (es) 1993-12-01
CZ341492A3 (en) 1993-07-14
TW238308B (forum.php) 1995-01-11
PH30098A (en) 1996-12-27
SK279251B6 (sk) 1998-08-05
NO930029D0 (no) 1993-01-06
EP0550895B1 (de) 1997-07-16
US5418224A (en) 1995-05-23
HU9204076D0 (en) 1993-04-28
GR3024859T3 (en) 1998-01-30
UA29393C2 (uk) 2000-11-15
FI930051L (fi) 1993-07-08
CA2086811A1 (en) 1993-07-08
FI106862B (fi) 2001-04-30
DE59208710D1 (de) 1997-08-21
CA2086811C (en) 2003-12-09
CN1033646C (zh) 1996-12-25
KR100273937B1 (ko) 2000-12-15
NO930029L (no) 1993-07-08
KR930016436A (ko) 1993-08-26
LTIP187A (lt) 1994-03-25
LV10458B (en) 1996-02-20
HUT66234A (en) 1994-10-28
IL104158A (en) 1997-07-13
FI930051A0 (fi) 1993-01-07
DZ1652A1 (fr) 2002-02-17
CZ281773B6 (cs) 1997-01-15
SK341492A3 (en) 1995-05-10
ES2104808T3 (es) 1997-10-16
NO179586B (no) 1996-07-29
CN1075320A (zh) 1993-08-18
DK0550895T3 (da) 1997-08-25
HK1014003A1 (en) 1999-09-17
AU667699B2 (en) 1996-04-04
LV10458A (lv) 1995-02-20
DE4200145A1 (de) 1993-07-08
EP0550895A1 (de) 1993-07-14
JP3300084B2 (ja) 2002-07-08
LT3015B (lt) 1994-08-25
RU2107070C1 (ru) 1998-03-20
ATE155478T1 (de) 1997-08-15
HU210216A9 (en) 1995-02-28
JPH07247299A (ja) 1995-09-26
NO179586C (no) 1996-11-06
IL104158A0 (en) 1993-05-13
HU212272B (en) 1996-04-29
AU3103693A (en) 1993-07-08

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