TW238308B - - Google Patents

Info

Publication number
TW238308B
TW238308B TW082102267A TW82102267A TW238308B TW 238308 B TW238308 B TW 238308B TW 082102267 A TW082102267 A TW 082102267A TW 82102267 A TW82102267 A TW 82102267A TW 238308 B TW238308 B TW 238308B
Authority
TW
Taiwan
Prior art keywords
isopropylerythromycin
demethyl
contracted
derivatives
preparation
Prior art date
Application number
TW082102267A
Other languages
English (en)
Chinese (zh)
Original Assignee
Kali Chemie Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma Gmbh filed Critical Kali Chemie Pharma Gmbh
Application granted granted Critical
Publication of TW238308B publication Critical patent/TW238308B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
TW082102267A 1992-01-07 1993-03-25 TW238308B (forum.php)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4200145A DE4200145A1 (de) 1992-01-07 1992-01-07 7,10-epoxy-oxacyclododecan-derivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
TW238308B true TW238308B (forum.php) 1995-01-11

Family

ID=6449136

Family Applications (1)

Application Number Title Priority Date Filing Date
TW082102267A TW238308B (forum.php) 1992-01-07 1993-03-25

Country Status (27)

Country Link
US (1) US5418224A (forum.php)
EP (1) EP0550895B1 (forum.php)
JP (1) JP3300084B2 (forum.php)
KR (1) KR100273937B1 (forum.php)
CN (1) CN1033646C (forum.php)
AT (1) ATE155478T1 (forum.php)
AU (1) AU667699B2 (forum.php)
CA (1) CA2086811C (forum.php)
CZ (1) CZ281773B6 (forum.php)
DE (2) DE4200145A1 (forum.php)
DK (1) DK0550895T3 (forum.php)
DZ (1) DZ1652A1 (forum.php)
ES (1) ES2104808T3 (forum.php)
FI (1) FI106862B (forum.php)
GR (1) GR3024859T3 (forum.php)
HU (2) HU212272B (forum.php)
IL (1) IL104158A (forum.php)
LT (1) LT3015B (forum.php)
LV (1) LV10458B (forum.php)
MX (1) MX9300045A (forum.php)
NO (1) NO179586C (forum.php)
PH (1) PH30098A (forum.php)
RU (1) RU2107070C1 (forum.php)
SK (1) SK279251B6 (forum.php)
TW (1) TW238308B (forum.php)
UA (1) UA29393C2 (forum.php)
ZA (1) ZA9339B (forum.php)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0859777T3 (da) * 1995-10-13 2007-09-03 Neurosearch As 8-azabicyclo[3.2.1]oct-2-en-derivater, deres fremstilling og anvendelse
US6077943A (en) * 1996-03-01 2000-06-20 Takeda Chemical Industries, Ltd. Method of producing erythromycin derivative
CA2247929A1 (en) * 1996-03-01 1997-09-04 Miichiro Arita Processes for the preparation of erythromycin derivatives
DE19644195A1 (de) * 1996-10-24 1998-04-30 Solvay Pharm Gmbh 10,13,15-Trioxatricyclo[9.2.1.1.·9·.·6·]-pentadecanon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19805822B4 (de) * 1998-02-13 2009-02-05 Solvay Pharmaceuticals Gmbh 11-Acetyl-12,13-dioxabicyclo[8.2.1]tridecenon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US6165985A (en) * 1998-02-13 2000-12-26 Solvay Pharmaceuticals Gmbh 11-acetyl-12,13-dioxabicyclo[8.2.1]-tridecenone derivatives, processes for their preparation and pharmaceutical compositions comprising them
HRP980496B1 (en) * 1998-09-10 2007-03-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. New thilozine hydroxy derivatives and a process for the preparation thereof
KR20040066186A (ko) * 2000-08-17 2004-07-23 샤단호칭키타사토겐큐쇼 신규 슈도에리쓰로마이신 유도체
JP3944077B2 (ja) * 2000-09-01 2007-07-11 中外製薬株式会社 エリスロマイシン誘導体の製造方法
ATE308537T1 (de) * 2001-05-10 2005-11-15 Solvay Pharm Gmbh Neue 1-amidomethylcarbonyl-piperidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US20040067896A1 (en) * 2002-07-25 2004-04-08 The Kitasato Institute Novel pseudoerythromycin derivatives
WO2004111077A1 (en) 2003-06-18 2004-12-23 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor
US7582611B2 (en) * 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
US20070135362A1 (en) * 2005-12-08 2007-06-14 Yaoquan Liu Method for demethylating the 3'-dimethylamino group of erythromycin compounds
EP2054429B1 (en) 2006-09-11 2013-11-06 Tranzyme Pharma, Inc. Macrocyclic antagonists of the motilin receptor for treatment of gastrointestinal dysmotility disorders
CN101547931B (zh) * 2006-12-05 2012-11-14 辉瑞有限公司 促动内酯多晶型
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
WO2014156339A1 (ja) * 2013-03-25 2014-10-02 ゼリア新薬工業株式会社 食後期の胃運動亢進剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725385A (en) 1970-11-02 1973-04-03 Abbott Lab Process for the demethylation of 3-amino macrolides
CA1321581C (en) * 1987-05-26 1993-08-24 Herbert A. Kirst Ring-contracted macrolides
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders

Also Published As

Publication number Publication date
HU210216A9 (en) 1995-02-28
FI106862B (fi) 2001-04-30
FI930051L (fi) 1993-07-08
MX9300045A (es) 1993-12-01
ZA9339B (en) 1993-08-05
CN1075320A (zh) 1993-08-18
HU9204076D0 (en) 1993-04-28
SK279251B6 (sk) 1998-08-05
CN1033646C (zh) 1996-12-25
IL104158A0 (en) 1993-05-13
LTIP187A (lt) 1994-03-25
FI930051A0 (fi) 1993-01-07
KR100273937B1 (ko) 2000-12-15
CZ341492A3 (en) 1993-07-14
UA29393C2 (uk) 2000-11-15
KR930016436A (ko) 1993-08-26
LV10458A (lv) 1995-02-20
ES2104808T3 (es) 1997-10-16
HUT66234A (en) 1994-10-28
DE4200145A1 (de) 1993-07-08
ATE155478T1 (de) 1997-08-15
JP3300084B2 (ja) 2002-07-08
PH30098A (en) 1996-12-27
NO930029L (no) 1993-07-08
HU212272B (en) 1996-04-29
NO179586C (no) 1996-11-06
AU3103693A (en) 1993-07-08
LT3015B (lt) 1994-08-25
NO930029D0 (no) 1993-01-06
SK341492A3 (en) 1995-05-10
JPH07247299A (ja) 1995-09-26
CA2086811C (en) 2003-12-09
NO179586B (no) 1996-07-29
HK1014003A1 (en) 1999-09-17
DK0550895T3 (da) 1997-08-25
GR3024859T3 (en) 1998-01-30
CA2086811A1 (en) 1993-07-08
EP0550895A1 (de) 1993-07-14
US5418224A (en) 1995-05-23
DZ1652A1 (fr) 2002-02-17
CZ281773B6 (cs) 1997-01-15
AU667699B2 (en) 1996-04-04
EP0550895B1 (de) 1997-07-16
RU2107070C1 (ru) 1998-03-20
DE59208710D1 (de) 1997-08-21
LV10458B (en) 1996-02-20
IL104158A (en) 1997-07-13

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