ZA924644B - Process for the manufacture of diacetylrhein - Google Patents

Process for the manufacture of diacetylrhein

Info

Publication number
ZA924644B
ZA924644B ZA924644A ZA924644A ZA924644B ZA 924644 B ZA924644 B ZA 924644B ZA 924644 A ZA924644 A ZA 924644A ZA 924644 A ZA924644 A ZA 924644A ZA 924644 B ZA924644 B ZA 924644B
Authority
ZA
South Africa
Prior art keywords
diacetylrhein
relates
liquid
aloe emodin
manufacture
Prior art date
Application number
ZA924644A
Other languages
English (en)
Inventor
Alfons Carcasona
Carcasona Alfons
Wolf Grimminger
Grimminger Wolf
Pentti Hietala
Hietala Pentti
Klaus Witthohn
Witthohn Klaus
Helga Zaeske
Zaeske Helga
Original Assignee
Madaus Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6434717&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA924644(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Madaus Ag filed Critical Madaus Ag
Publication of ZA924644B publication Critical patent/ZA924644B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/48—Separation; Purification; Stabilisation; Use of additives
    • C07C67/56—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/24—Anthracenes; Hydrogenated anthracenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Holo Graphy (AREA)
  • Electroluminescent Light Sources (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
ZA924644A 1991-06-25 1992-06-24 Process for the manufacture of diacetylrhein ZA924644B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4120989A DE4120989C2 (de) 1991-06-25 1991-06-25 Verfahren zur Herstellung von Diacetylrhein

Publications (1)

Publication Number Publication Date
ZA924644B true ZA924644B (en) 1993-03-31

Family

ID=6434717

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA924644A ZA924644B (en) 1991-06-25 1992-06-24 Process for the manufacture of diacetylrhein

Country Status (19)

Country Link
US (2) US5391775A (zh)
EP (1) EP0520414B1 (zh)
JP (1) JPH0825955B2 (zh)
AT (1) ATE135341T1 (zh)
AU (1) AU645208B2 (zh)
CA (1) CA2072283C (zh)
CZ (1) CZ194892A3 (zh)
DE (2) DE4120989C2 (zh)
DK (1) DK0520414T3 (zh)
ES (1) ES2084877T3 (zh)
FI (1) FI104892B (zh)
GR (1) GR3019321T3 (zh)
HU (1) HU220390B (zh)
IE (1) IE72526B1 (zh)
PL (1) PL168847B1 (zh)
RU (1) RU2104996C1 (zh)
SK (1) SK194892A3 (zh)
TW (1) TW400333B (zh)
ZA (1) ZA924644B (zh)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5710260A (en) * 1991-06-25 1998-01-20 Madaus Ag Method of extracting sennosides A, B and A1
IT1264545B1 (it) * 1993-07-30 1996-10-02 Medidom Lab Procedimento per la preparazione della diacereina
FI96692C (fi) * 1993-12-17 1996-08-12 Leiras Oy Menetelmä sennosidien A ja B valmistamiseksi
CH689279A5 (fr) * 1995-02-07 1999-01-29 Steba Beheer Bv Procédé de purification de la diacétylrhéine.
US5652265A (en) * 1995-03-29 1997-07-29 Wisconsin Alumni Research Foundation Production of rhein and rhein derivatives
WO2003000246A1 (en) * 2001-06-25 2003-01-03 Arakis Ltd. The use of rhein and derivatives thereof in pain treatment
ITMI20022535A1 (it) * 2002-11-29 2004-05-30 Synteco Spa Procedimento per la purificazione della diacereina.
MXPA03008622A (es) * 2003-09-23 2005-03-30 Interquim S A De C V Metodo de purificacion de diacereina cruda por la via del tolueno.
EP2196450A1 (en) 2008-12-09 2010-06-16 Evultis S.A. Process for the preparation of pure diacetylrhein (diacerein)
EP2364287B1 (en) * 2008-12-09 2014-04-02 Evultis S.A. Process for the preparation of non-genotoxic diacetylrhein (diacerein) and formulations comprising non-genotoxic diacetylrhein
EP2218707A1 (en) 2009-02-16 2010-08-18 Evultis S.A. Process for the preparation of non-genotoxic Diacetylrhein (Diacerein)
WO2011099834A2 (es) * 2010-02-15 2011-08-18 Interquim, S.A. De C.V. Procedimiento para la purificación de diacereina cruda vía sal de potasio/dimetil formamida
ITTO20110120A1 (it) 2011-02-11 2012-08-12 Icrom Spa Un nuovo processo di purificazione per derivati antrachinonici
AU2013290277B2 (en) * 2012-07-10 2016-07-21 Children's Healthcare Of Atlanta, Inc. Anthraquinone analogs and methods of making and using thereof
CN105985242A (zh) * 2015-01-27 2016-10-05 邵阳学院 双醋瑞因制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA761627B (en) * 1976-03-16 1978-01-25 C Friedmann Improvements in or relating to the treatment of arthritis
DE3200131A1 (de) * 1982-01-05 1983-07-14 Madaus & Co Dr "verfahren zur gewinnung von laxativen verbindungen aus sennadroge"
IT1189097B (it) * 1986-05-02 1988-01-28 Proter Spa Sali di diacetilreina e loro impiego terapeutico nel trattamento dell'artrosi

Also Published As

Publication number Publication date
IE922046A1 (en) 1992-12-30
JPH0825955B2 (ja) 1996-03-13
DE4120989C2 (de) 1995-07-27
EP0520414A1 (de) 1992-12-30
DE59205646D1 (de) 1996-04-18
EP0520414B1 (de) 1996-03-13
PL168847B1 (pl) 1996-04-30
HU220390B (hu) 2002-01-28
PL295006A1 (en) 1993-02-22
FI922930A0 (fi) 1992-06-24
ATE135341T1 (de) 1996-03-15
TW400333B (en) 2000-08-01
CA2072283C (en) 2000-10-24
JPH05186394A (ja) 1993-07-27
AU1848492A (en) 1993-03-11
US5391775A (en) 1995-02-21
ES2084877T3 (es) 1996-05-16
FI104892B (fi) 2000-04-28
FI922930A (fi) 1992-12-26
SK194892A3 (en) 1995-02-08
CA2072283A1 (en) 1992-12-26
DK0520414T3 (da) 1996-04-01
GR3019321T3 (en) 1996-06-30
DE4120989A1 (de) 1993-01-07
HU9202108D0 (en) 1992-10-28
HUT61263A (en) 1992-12-28
CZ194892A3 (en) 1993-01-13
IE72526B1 (en) 1997-04-23
RU2104996C1 (ru) 1998-02-20
AU645208B2 (en) 1994-01-06
US6624192B1 (en) 2003-09-23

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