FI922930A - Foerfarande foer framstaellning av diacetylrhein - Google Patents

Foerfarande foer framstaellning av diacetylrhein Download PDF

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Publication number
FI922930A
FI922930A FI922930A FI922930A FI922930A FI 922930 A FI922930 A FI 922930A FI 922930 A FI922930 A FI 922930A FI 922930 A FI922930 A FI 922930A FI 922930 A FI922930 A FI 922930A
Authority
FI
Finland
Prior art keywords
diacetylrhein
foerfarande foer
foer framstaellning
relates
liquid
Prior art date
Application number
FI922930A
Other languages
English (en)
Other versions
FI104892B (fi
FI922930A0 (fi
Inventor
Alfons Carcasona
Wolf Grimminger
Pentti Hietala
Klaus Witthohn
Helga Zaeske
Original Assignee
Madaus Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6434717&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI922930(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Madaus Ag filed Critical Madaus Ag
Publication of FI922930A0 publication Critical patent/FI922930A0/fi
Publication of FI922930A publication Critical patent/FI922930A/fi
Application granted granted Critical
Publication of FI104892B publication Critical patent/FI104892B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/08Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/48Separation; Purification; Stabilisation; Use of additives
    • C07C67/56Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/24Anthracenes; Hydrogenated anthracenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Electroluminescent Light Sources (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Holo Graphy (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
FI922930A 1991-06-25 1992-06-24 Diasetyylirheinin valmistusmenetelmä FI104892B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4120989 1991-06-25
DE4120989A DE4120989C2 (de) 1991-06-25 1991-06-25 Verfahren zur Herstellung von Diacetylrhein

Publications (3)

Publication Number Publication Date
FI922930A0 FI922930A0 (fi) 1992-06-24
FI922930A true FI922930A (fi) 1992-12-26
FI104892B FI104892B (fi) 2000-04-28

Family

ID=6434717

Family Applications (1)

Application Number Title Priority Date Filing Date
FI922930A FI104892B (fi) 1991-06-25 1992-06-24 Diasetyylirheinin valmistusmenetelmä

Country Status (19)

Country Link
US (2) US5391775A (fi)
EP (1) EP0520414B1 (fi)
JP (1) JPH0825955B2 (fi)
AT (1) ATE135341T1 (fi)
AU (1) AU645208B2 (fi)
CA (1) CA2072283C (fi)
CZ (1) CZ194892A3 (fi)
DE (2) DE4120989C2 (fi)
DK (1) DK0520414T3 (fi)
ES (1) ES2084877T3 (fi)
FI (1) FI104892B (fi)
GR (1) GR3019321T3 (fi)
HU (1) HU220390B (fi)
IE (1) IE72526B1 (fi)
PL (1) PL168847B1 (fi)
RU (1) RU2104996C1 (fi)
SK (1) SK194892A3 (fi)
TW (1) TW400333B (fi)
ZA (1) ZA924644B (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5710260A (en) * 1991-06-25 1998-01-20 Madaus Ag Method of extracting sennosides A, B and A1
IT1264545B1 (it) * 1993-07-30 1996-10-02 Medidom Lab Procedimento per la preparazione della diacereina
FI96692C (fi) * 1993-12-17 1996-08-12 Leiras Oy Menetelmä sennosidien A ja B valmistamiseksi
CH689279A5 (fr) * 1995-02-07 1999-01-29 Steba Beheer Bv Procédé de purification de la diacétylrhéine.
US5652265A (en) * 1995-03-29 1997-07-29 Wisconsin Alumni Research Foundation Production of rhein and rhein derivatives
WO2003000246A1 (en) * 2001-06-25 2003-01-03 Arakis Ltd. The use of rhein and derivatives thereof in pain treatment
ITMI20022535A1 (it) * 2002-11-29 2004-05-30 Synteco Spa Procedimento per la purificazione della diacereina.
MXPA03008622A (es) * 2003-09-23 2005-03-30 Interquim S A De C V Metodo de purificacion de diacereina cruda por la via del tolueno.
US8598232B2 (en) 2008-12-09 2013-12-03 Evultis Sa Process for the preparation of non-genotoxic diacetylrhein (diacerein) and formulations comprising non-genotoxic diacetylrhein
EP2218707A1 (en) 2009-02-16 2010-08-18 Evultis S.A. Process for the preparation of non-genotoxic Diacetylrhein (Diacerein)
EP2196450A1 (en) 2008-12-09 2010-06-16 Evultis S.A. Process for the preparation of pure diacetylrhein (diacerein)
WO2011099834A2 (es) * 2010-02-15 2011-08-18 Interquim, S.A. De C.V. Procedimiento para la purificación de diacereina cruda vía sal de potasio/dimetil formamida
ITTO20110120A1 (it) 2011-02-11 2012-08-12 Icrom Spa Un nuovo processo di purificazione per derivati antrachinonici
JP2015527322A (ja) * 2012-07-10 2015-09-17 ジョージア ステイト ユニバーシティ リサーチ ファンデーション, インコーポレイテッド アントラキノン類似体ならびにその作製方法および使用方法
CN105985242A (zh) * 2015-01-27 2016-10-05 邵阳学院 双醋瑞因制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA761627B (en) * 1976-03-16 1978-01-25 C Friedmann Improvements in or relating to the treatment of arthritis
DE3200131A1 (de) * 1982-01-05 1983-07-14 Madaus & Co Dr "verfahren zur gewinnung von laxativen verbindungen aus sennadroge"
IT1189097B (it) * 1986-05-02 1988-01-28 Proter Spa Sali di diacetilreina e loro impiego terapeutico nel trattamento dell'artrosi

Also Published As

Publication number Publication date
EP0520414A1 (de) 1992-12-30
ZA924644B (en) 1993-03-31
CA2072283A1 (en) 1992-12-26
DE4120989C2 (de) 1995-07-27
FI104892B (fi) 2000-04-28
ES2084877T3 (es) 1996-05-16
IE72526B1 (en) 1997-04-23
US5391775A (en) 1995-02-21
CA2072283C (en) 2000-10-24
HU220390B (hu) 2002-01-28
GR3019321T3 (en) 1996-06-30
PL295006A1 (en) 1993-02-22
DE4120989A1 (de) 1993-01-07
IE922046A1 (en) 1992-12-30
AU1848492A (en) 1993-03-11
JPH0825955B2 (ja) 1996-03-13
AU645208B2 (en) 1994-01-06
JPH05186394A (ja) 1993-07-27
ATE135341T1 (de) 1996-03-15
RU2104996C1 (ru) 1998-02-20
SK194892A3 (en) 1995-02-08
CZ194892A3 (en) 1993-01-13
HU9202108D0 (en) 1992-10-28
HUT61263A (en) 1992-12-28
TW400333B (en) 2000-08-01
PL168847B1 (pl) 1996-04-30
US6624192B1 (en) 2003-09-23
FI922930A0 (fi) 1992-06-24
EP0520414B1 (de) 1996-03-13
DE59205646D1 (de) 1996-04-18
DK0520414T3 (da) 1996-04-01

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