ZA918965B - Nucleic acid amplification by two-enzyme,self-sustained sequence replication - Google Patents
Nucleic acid amplification by two-enzyme,self-sustained sequence replicationInfo
- Publication number
- ZA918965B ZA918965B ZA918965A ZA918965A ZA918965B ZA 918965 B ZA918965 B ZA 918965B ZA 918965 A ZA918965 A ZA 918965A ZA 918965 A ZA918965 A ZA 918965A ZA 918965 B ZA918965 B ZA 918965B
- Authority
- ZA
- South Africa
- Prior art keywords
- enzyme
- self
- nucleic acid
- acid amplification
- sequence replication
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61268890A | 1990-11-13 | 1990-11-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA918965B true ZA918965B (en) | 1992-08-26 |
Family
ID=24454235
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA918965A ZA918965B (en) | 1990-11-13 | 1991-11-12 | Nucleic acid amplification by two-enzyme,self-sustained sequence replication |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0572417A4 (pt) |
JP (1) | JPH06502767A (pt) |
AU (1) | AU9131591A (pt) |
CA (1) | CA2096013A1 (pt) |
FI (1) | FI932144A (pt) |
HU (1) | HUT69772A (pt) |
IE (1) | IE913930A1 (pt) |
IL (1) | IL100040A (pt) |
NO (1) | NO931709L (pt) |
NZ (1) | NZ240574A (pt) |
PT (1) | PT99500A (pt) |
WO (1) | WO1992008800A1 (pt) |
ZA (1) | ZA918965B (pt) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0628076A1 (en) * | 1992-11-19 | 1994-12-14 | GINGERAS, Thomas R. | PRODUCTION OF MONOCLONAL RECOMBINANT ANTIBODIES WITHOUT THE USE OF HYBRIDOMAS BY $i(IN VITRO) SPLEEN FRAGMENT CULTURE COMBINED WITH ISOTHERMAL SELF-SUSTAINED SEQUENCE REPLICATION OF RNA |
EP0682121B1 (en) * | 1993-12-01 | 2002-08-28 | Toyo Boseki Kabushiki Kaisha | Method of amplifying and detecting target nucleic acid sequence by using thermostable enzymes |
US5705366A (en) * | 1994-09-15 | 1998-01-06 | Johnson & Johnson Clinical Diagnostics, Inc. | Coamplification of target nucleic acids using volume exclusion agent in reaction composition, test kit and test device useful therefor |
JPH08131171A (ja) * | 1994-11-11 | 1996-05-28 | Asahi Chem Ind Co Ltd | 逆転写酵素の安定化組成物 |
US5763184A (en) | 1996-01-30 | 1998-06-09 | Roche Molecular Systems, Inc. | Nucleotide sequence variation in the ABO glycosyltransferase gene |
WO2000000638A2 (en) * | 1998-06-26 | 2000-01-06 | Akzo Nobel N.V. | Tagging of rna amplicons generated by transcription-based amplification |
JP2001029078A (ja) * | 1999-07-16 | 2001-02-06 | Shimadzu Corp | Rna増幅法 |
WO2002012263A1 (en) | 2000-08-03 | 2002-02-14 | Roche Diagnostics Gmbh | Nucleic acid binding compounds containing pyrazolo[3,4-d]pyrimidine analogues of purin-2,6-diamine and their uses |
US6780588B2 (en) | 2001-05-07 | 2004-08-24 | Applera Corporation | Methods for the reduction of stutter in microsatellite amplification |
US6841349B2 (en) | 2001-05-07 | 2005-01-11 | Applera Corporation Applied Biosystems Group | Methods for the reduction of stutter in microsatellite amplification |
US20040161741A1 (en) | 2001-06-30 | 2004-08-19 | Elazar Rabani | Novel compositions and processes for analyte detection, quantification and amplification |
US9777312B2 (en) | 2001-06-30 | 2017-10-03 | Enzo Life Sciences, Inc. | Dual polarity analysis of nucleic acids |
US9261460B2 (en) | 2002-03-12 | 2016-02-16 | Enzo Life Sciences, Inc. | Real-time nucleic acid detection processes and compositions |
WO2003057910A2 (en) | 2002-01-08 | 2003-07-17 | Roche Diagnostics Gmbh | Use of silica material in an amplification reaction |
US7122314B2 (en) | 2002-01-30 | 2006-10-17 | Id Biomedical Corporation | Methods for detecting vancomycin-resistant microorganisms and compositions therefor |
US9353405B2 (en) | 2002-03-12 | 2016-05-31 | Enzo Life Sciences, Inc. | Optimized real time nucleic acid detection processes |
DE10240868A1 (de) * | 2002-09-04 | 2004-03-18 | Artus Gesellschaft für molekularbiologische Diagnostik und Entwicklung mbH | Verbesserte Verfahren zur Synthese von Nukleinsäuren |
DE602004009038T3 (de) | 2003-01-29 | 2015-06-25 | Roche Diagnostics Gmbh | Verbessertes Verfahren zur Behandlung durch Bisulfit |
JP2004357502A (ja) * | 2003-05-30 | 2004-12-24 | Olympus Corp | 核酸分子を使用した情報処理方法 |
WO2006006722A1 (ja) | 2004-07-13 | 2006-01-19 | Takeda Pharmaceutical Company Limited | 細胞機能の調節方法 |
EP1632578A1 (en) | 2004-09-03 | 2006-03-08 | Roche Diagnostics GmbH | DNA decontamination method |
GB0701253D0 (en) | 2007-01-23 | 2007-02-28 | Diagnostics For The Real World | Nucleic acid amplification and testing |
AU2008283902B2 (en) | 2007-08-06 | 2014-03-13 | Orion Genomics Llc | Novel single nucleotide polymorphisms and combinations of novel and known polymorphisms for determining the allele-specific expression of the IGF2 gene |
CA2639416C (en) | 2007-09-11 | 2019-12-31 | F. Hoffmann-La Roche Ag | Diagnostic test for susceptibility to b-raf kinase inhibitors |
AU2008318316B2 (en) | 2007-11-01 | 2015-08-06 | University Of Iowa Research Foundation | RCA locus analysis to assess susceptibility to AMD and MPGNII |
EP2396429B1 (en) | 2009-02-11 | 2015-05-27 | Orion Genomics, LLC | Combinations of polymorphisms for determining allele-specific expression of igf2 |
WO2011128096A1 (en) | 2010-04-16 | 2011-10-20 | Roche Diagnostics Gmbh | Polymorphism markers for predicting response to interleukin-6 receptor-inhibiting monoclonal antibody drug treatment |
US20130143214A1 (en) | 2010-06-04 | 2013-06-06 | Chronix Biomedical | Prostate cancer associated circulating nucleic acid biomarkers |
US20140004510A1 (en) | 2010-09-24 | 2014-01-02 | Massachusetts Eye And Ear Infirmary | Methods and compositions for prognosing and/or detecting age-related macular degeneration |
US9458484B2 (en) | 2010-10-22 | 2016-10-04 | Bio-Rad Laboratories, Inc. | Reverse transcriptase mixtures with improved storage stability |
EP2751280B1 (en) | 2011-08-31 | 2016-06-29 | F.Hoffmann-La Roche Ag | Method for predicting risk of hypertension associated with anti-angiogenesis therapy |
WO2013030167A1 (en) | 2011-08-31 | 2013-03-07 | F. Hoffmann-La Roche Ag | Responsiveness to angiogenesis inhibitors |
KR20140064971A (ko) | 2011-09-19 | 2014-05-28 | 제넨테크, 인크. | c-met 길항제 및 B-raf 길항제를 포함하는 조합 치료 |
US20140303008A1 (en) | 2011-10-21 | 2014-10-09 | Chronix Biomedical | Colorectal cancer associated circulating nucleic acid biomarkers |
EP2783015A1 (en) | 2011-11-23 | 2014-10-01 | F.Hoffmann-La Roche Ag | Responsiveness to angiogenesis inhibitors |
US9115394B2 (en) | 2011-12-22 | 2015-08-25 | Roche Molecular Systems, Inc. | Methods and reagents for reducing non-specific amplification |
US20160115541A1 (en) | 2013-05-29 | 2016-04-28 | Chronix Biomedical | Detection and quantification of donor cell-free dna in the circulation of organ transplant recipients |
KR20160138494A (ko) | 2014-03-31 | 2016-12-05 | 데비오팜 인터네셔날 에스 에이 | Fgfr 융합물 |
US20160168640A1 (en) | 2014-11-10 | 2016-06-16 | Genentech, Inc. | Therapeutic and diagnostic methods for il-33-mediated disorders |
ES2961374T3 (es) | 2015-04-24 | 2024-03-11 | Atila Biosystems Incorporated | Amplificación con cebadores de composición de nucleótidos limitada |
PT3640345T (pt) | 2015-08-17 | 2021-12-29 | Kura Oncology Inc | Métodos de tratamento de doentes com cancro usando inibidores da farnesiltransferase |
US20190119758A1 (en) | 2016-04-22 | 2019-04-25 | Kura Oncology, Inc. | Methods of selecting cancer patients for treatment with farnesyltransferase inhibitors |
DK3534885T3 (da) | 2016-11-03 | 2021-04-12 | Kura Oncology Inc | Farnesyltransferase-inhibitorer til anvendelse i behandling af kræft |
EP3432883B1 (en) | 2017-02-21 | 2021-07-28 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
US10137121B2 (en) | 2017-02-21 | 2018-11-27 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
MY200746A (en) | 2017-08-07 | 2024-01-13 | Kura Oncology Inc | Methods of treating cancer with farnesyltransferase inhibitors |
US10806730B2 (en) | 2017-08-07 | 2020-10-20 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
KR20230142806A (ko) | 2018-02-09 | 2023-10-11 | 제넨테크, 인크. | 비만 세포 매개 염증성 질환에 대한 치료 및 진단 방법 |
CA3117968A1 (en) | 2018-11-01 | 2020-05-07 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
US20220142983A1 (en) | 2019-03-01 | 2022-05-12 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
CN113795253A (zh) | 2019-03-29 | 2021-12-14 | 库拉肿瘤学公司 | 用法呢基转移酶抑制剂治疗鳞状细胞癌的方法 |
TW202102218A (zh) | 2019-04-01 | 2021-01-16 | 美商庫拉腫瘤技術股份有限公司 | 以法呢基(farnesyl)轉移酶抑制劑治療癌症的方法 |
US20220305001A1 (en) | 2019-05-02 | 2022-09-29 | Kura Oncology, Inc. | Methods of treating acute myeloid leukemia with farnesyltransferase inhibitors |
US20230110203A1 (en) | 2020-03-13 | 2023-04-13 | Medimmune Limited | Therapeutic methods for the treatment of subjects with risk alelles in il33 |
WO2024015331A1 (en) | 2022-07-12 | 2024-01-18 | Genentech, Inc. | Therapeutic and diagnostic methods for multiple sclerosis |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4800159A (en) * | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
CA1340807C (en) * | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
ZA899593B (en) * | 1988-12-16 | 1990-09-26 | Siska Diagnostics Inc | Self-sustained,sequence replication system |
ATE282716T1 (de) * | 1989-07-11 | 2004-12-15 | Gen Probe Inc | Verfahren zur amplifikation von nukleinsäuresequenzen |
-
1991
- 1991-11-12 ZA ZA918965A patent/ZA918965B/xx unknown
- 1991-11-12 IE IE393091A patent/IE913930A1/en not_active Application Discontinuation
- 1991-11-12 IL IL10004091A patent/IL100040A/en not_active IP Right Cessation
- 1991-11-13 NZ NZ240574A patent/NZ240574A/en unknown
- 1991-11-13 HU HU9301369A patent/HUT69772A/hu unknown
- 1991-11-13 AU AU91315/91A patent/AU9131591A/en not_active Abandoned
- 1991-11-13 JP JP4502286A patent/JPH06502767A/ja active Pending
- 1991-11-13 CA CA002096013A patent/CA2096013A1/en not_active Abandoned
- 1991-11-13 EP EP19920901557 patent/EP0572417A4/en not_active Ceased
- 1991-11-13 WO PCT/US1991/008488 patent/WO1992008800A1/en not_active Application Discontinuation
- 1991-11-13 PT PT99500A patent/PT99500A/pt not_active Application Discontinuation
-
1993
- 1993-05-11 NO NO93931709A patent/NO931709L/no unknown
- 1993-05-12 FI FI932144A patent/FI932144A/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1992008800A1 (en) | 1992-05-29 |
IL100040A (en) | 1995-12-31 |
HU9301369D0 (en) | 1993-10-28 |
FI932144A0 (fi) | 1993-05-12 |
NO931709D0 (no) | 1993-05-11 |
JPH06502767A (ja) | 1994-03-31 |
PT99500A (pt) | 1992-10-30 |
EP0572417A1 (en) | 1993-12-08 |
IL100040A0 (en) | 1992-08-18 |
IE913930A1 (en) | 1992-06-17 |
NO931709L (no) | 1993-07-12 |
EP0572417A4 (en) | 1994-11-23 |
NZ240574A (en) | 1994-10-26 |
AU9131591A (en) | 1992-06-11 |
FI932144A (fi) | 1993-05-12 |
CA2096013A1 (en) | 1992-05-14 |
HUT69772A (en) | 1995-09-28 |
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