ZA916741B - Propellant-free inhalation device with foreign air stream - Google Patents

Propellant-free inhalation device with foreign air stream

Info

Publication number
ZA916741B
ZA916741B ZA916741A ZA916741A ZA916741B ZA 916741 B ZA916741 B ZA 916741B ZA 916741 A ZA916741 A ZA 916741A ZA 916741 A ZA916741 A ZA 916741A ZA 916741 B ZA916741 B ZA 916741B
Authority
ZA
South Africa
Prior art keywords
substance
propellant
air stream
dose
button
Prior art date
Application number
ZA916741A
Other languages
English (en)
Inventor
Gerhard Poss
Poss Gerhard
Juergen Wittekind
Wittekind Juergen
Andreas Kuehnel
Kuehnel Andreas
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of ZA916741B publication Critical patent/ZA916741B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0096—Hindering inhalation before activation of the dispenser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/073—Syringe, piston type

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medicinal Preparation (AREA)
  • Lasers (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
  • External Artificial Organs (AREA)
  • Sorption Type Refrigeration Machines (AREA)
  • Feeding And Controlling Fuel (AREA)
  • Nozzles (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
  • Treating Waste Gases (AREA)
  • Engine Equipment That Uses Special Cycles (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA916741A 1990-08-30 1991-08-26 Propellant-free inhalation device with foreign air stream ZA916741B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4027391A DE4027391A1 (de) 1990-08-30 1990-08-30 Treibgasfreies inhalationsgeraet

Publications (1)

Publication Number Publication Date
ZA916741B true ZA916741B (en) 1992-05-27

Family

ID=6413200

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA916741A ZA916741B (en) 1990-08-30 1991-08-26 Propellant-free inhalation device with foreign air stream

Country Status (26)

Country Link
US (1) US5617845A (fr)
EP (1) EP0549605B1 (fr)
JP (1) JP2505339B2 (fr)
KR (1) KR0179376B1 (fr)
AT (1) ATE116558T1 (fr)
AU (1) AU654499B2 (fr)
CA (1) CA2090227C (fr)
CZ (1) CZ281264B6 (fr)
DE (2) DE4027391A1 (fr)
DK (1) DK0549605T3 (fr)
EE (1) EE03092B1 (fr)
ES (1) ES2066463T3 (fr)
FI (1) FI105078B (fr)
GR (1) GR3015540T3 (fr)
HU (1) HU213661B (fr)
IE (1) IE71162B1 (fr)
IL (1) IL99285A (fr)
LT (1) LT3125B (fr)
LV (1) LV10398B (fr)
NO (1) NO304353B1 (fr)
NZ (1) NZ239530A (fr)
PL (1) PL166852B1 (fr)
RU (1) RU2098144C1 (fr)
SK (1) SK278886B6 (fr)
WO (1) WO1992004068A1 (fr)
ZA (1) ZA916741B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840279A (en) * 1995-06-21 1998-11-24 Asta Medica Aktiengesellschaft Pharmaceutical powder cartridge with integrated metering device and inhaler for powdered medicaments
EP1616592A1 (fr) 2004-07-16 2006-01-18 Sofotec GmbH & Co. KG Inhalateur pour l'administration des composés pharmaceutiques en poudre, et cartouche de poudre utilisée avec cet inhalateur
US7954492B2 (en) 2002-01-24 2011-06-07 Almirall, S.A. Pharmaceutical powder cartridge, and inhaler equipped with same

Families Citing this family (138)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE224748T1 (de) * 1989-04-28 2002-10-15 Riker Laboratories Inc Inhalationsvorrichtung für trockenpulver
US5507281A (en) * 1990-08-30 1996-04-16 Boehringer Ingelheim Kg Device for initiating a mechanical switching operation in synchronism with the breathing
DE4133274A1 (de) * 1991-08-22 1993-02-25 Boehringer Ingelheim Kg Vorrichtung zum atemzugsynchronen ausloesen eines mechanischen schaltvorganges
AU2513092A (en) * 1991-08-26 1993-03-16 Minnesota Mining And Manufacturing Company Powder dispenser
US6029661A (en) * 1991-08-26 2000-02-29 3M Innovative Properties Company Powder dispenser
EP0632734B1 (fr) * 1992-03-25 1998-06-10 Tebro S.A. Distributeur a jet de poudre pour traitements par inhalation de medicament
DE59303719D1 (de) * 1992-06-05 1996-10-17 Hoechst Ag Inhalator
US5394868A (en) * 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments
DE69331635T2 (de) * 1992-11-12 2002-10-31 Minnesota Mining And Mfg. Co., Saint Paul Pulverinhalator
FR2700279B1 (fr) * 1993-01-14 1995-03-17 Valois Dispositif portatif pour projeter des doses d'une substance fluide à l'aide d'un flux d'air comprimé.
FR2701653B1 (fr) * 1993-02-18 1995-04-07 Valois Dispositif doseur pour l'inhalation de poudre sèche.
DE4319514C2 (de) * 1993-06-14 2003-06-18 Sofotec Gmbh & Co Kg Pulverinhalator
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
FR2718968B1 (fr) * 1994-04-20 1996-07-26 Valois Sa Insert délimitant une chambre de dosage d'un inhalateur.
FI95441C (fi) * 1994-05-31 1996-02-12 Leiras Oy Inhalointilaitteen lääkeainekammio
DE19522415C2 (de) * 1995-06-21 2003-12-04 Sofotec Gmbh & Co Kg Arzneimittelpulverpatrone mit integrierter Dosiereinrichtung und Pulverinhalator mit Mitteln zum Betätigen der Dosiereinrichtung der Arzneimittelpulverpatrone
JP3317823B2 (ja) * 1995-08-11 2002-08-26 株式会社ユニシアジェックス 投薬器
FR2738153B1 (fr) * 1995-09-04 1998-01-02 Valois Appareil d'inhalation destine a distribuer des doses precises et reproductibles de produit pulverulent
SE9700937D0 (sv) 1997-03-14 1997-03-14 Astra Ab Powder inhaler I
SE9700936D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Inhalation device
SE9700935D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Inhalation device
TW469832U (en) 1997-03-14 2001-12-21 Astra Ab Inhalation device
GB9719093D0 (en) 1997-09-10 1997-11-12 Ml Lab Plc Improvements to dry powder inhalers
US5954047A (en) * 1997-10-17 1999-09-21 Systemic Pulmonary Development, Ltd. Methods and apparatus for delivering aerosolized medication
ES2207030T3 (es) 1998-01-30 2004-05-16 Hagepharm Gmbh Inhalador para medicamentos en forma de polvo.
DE19825434C2 (de) * 1998-01-30 2002-03-28 Ig Spruehtechnik Gmbh Inhalationsgerät für pulverförmige Medikamente
US6223746B1 (en) * 1998-02-12 2001-05-01 Iep Pharmaceutical Devices Inc. Metered dose inhaler pump
EA003196B1 (ru) * 1998-03-16 2003-02-27 Инхэл Терапьютик Системз, Инк Способ подачи действующего вещества в виде аэрозоля
US6260549B1 (en) 1998-06-18 2001-07-17 Clavius Devices, Inc. Breath-activated metered-dose inhaler
ES2228070T3 (es) 1998-06-22 2005-04-01 Astrazeneca Ab Dispositivo para aspirar y vaciar cavidades que contienen polvo.
UA73924C2 (en) * 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
FI990915A0 (fi) * 1999-04-23 1999-04-23 Orion Yhtymae Oyj Jauheinhalaattori
EP1183061B2 (fr) * 1999-06-05 2012-10-17 Innovata Biomed Limited Systeme d'administration de medicaments
US6606992B1 (en) * 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
GB9920839D0 (en) 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
US6626171B2 (en) 2000-05-12 2003-09-30 Iep Pharmaceutical Devices Inc. Powder/liquid metering valve
GB0015043D0 (en) * 2000-06-21 2000-08-09 Glaxo Group Ltd Medicament dispenser
WO2002013897A2 (fr) 2000-08-14 2002-02-21 Advanced Inhalation Research, Inc. Inhalateur et procede correspondant
DE10047722A1 (de) 2000-09-27 2002-04-11 Schuckmann Alfred Von Von Saugluftstrom des Benutzers aktivierbare Dosiervorrichtung
US20110301569A1 (en) 2001-01-20 2011-12-08 Gordon Wayne Dyer Methods and apparatus for the CVCS
WO2002062317A2 (fr) * 2001-02-06 2002-08-15 Innovata Biomed Limited Medicaments
US6766799B2 (en) * 2001-04-16 2004-07-27 Advanced Inhalation Research, Inc. Inhalation device
FI20011317A0 (fi) * 2001-06-20 2001-06-20 Orion Corp Jauheinhalaattori
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
DE10165112B3 (de) * 2001-09-11 2013-08-01 Sanofi Sa Inhalator für pulverförmige, insbesondere medizinische Substanzen
DE10144572B4 (de) * 2001-09-11 2013-08-01 Sanofi Sa Inhalator für pulverförmige, insbesondere medizinische Substanzen
DE10165101B3 (de) * 2001-09-11 2014-02-13 Sanofi Sa Inhalator für pulverförmige, insbesondere medizinische Substanzen
GB0128148D0 (en) * 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
US20030168057A1 (en) * 2001-12-14 2003-09-11 Inhale Therapeutic Systems, Inc. Electronically controllable aerosol delivery
US7185651B2 (en) * 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
US20060118106A1 (en) 2002-09-16 2006-06-08 Alfred Von Schuckmann Inhaler for powdery, in particular, medical substances
EP1905472A3 (fr) 2002-09-16 2008-04-16 von Schuckmann, Alfred Inhalateur pour substances pulvérulentes, en particulier pour substances médicales
FR2849386B1 (fr) * 2002-12-27 2005-03-18 Bertin Technologies Sa Dispositif d'inhalation de poudre seche
US20050026948A1 (en) * 2003-07-29 2005-02-03 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising an anticholinergic and a betamimetic
GB0407627D0 (en) * 2004-04-02 2004-05-05 Vectura Ltd Corkscrew pump
BRPI0509348A (pt) * 2004-04-21 2007-09-11 Innovata Biomed Ltd inalador
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
SI1905451T1 (sl) 2004-05-31 2010-05-31 Almirall Sa Kombinacije ki obsegajo antimuskarinska sredstvain kortikosteroide
ES2257152B1 (es) * 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
ES2265276B1 (es) 2005-05-20 2008-02-01 Laboratorios Almirall S.A. Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico.
DE102005033397A1 (de) 2005-07-18 2007-01-25 Alfred Von Schuckmann Inhalator für pulverförmige, insbesondere medizinische Substanzen
GB2433207B (en) 2006-02-21 2009-01-07 Jianhe Li Active suction actuated inhalers with timing devices
DE102006029753A1 (de) 2006-03-10 2007-09-13 Alfred Von Schuckmann Inhalator für pulverförmige Substanzen
GB0614621D0 (en) * 2006-07-24 2006-08-30 3M Innovative Properties Co Metered dose dispensers
DE102006044752A1 (de) 2006-09-20 2008-04-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Kolbendosierer
US20100139655A1 (en) * 2006-11-19 2010-06-10 Aespironics Ltd Dry-powder inhaler
MX2009006787A (es) 2006-12-22 2009-07-10 Almirall Lab Dispositivo de inhalacion para medicamentos en forma de polvo.
ES2306595B1 (es) 2007-02-09 2009-09-11 Laboratorios Almirall S.A. Sal de napadisilato de 5-(2-((6-(2,2-difluoro-2-feniletoxi)hexil)amino)-1-hidroxietil)-8-hidroxiquinolin-2(1h)-ona como agonista del receptor adrenergico beta2.
WO2008101991A1 (fr) * 2007-02-21 2008-08-28 Novo Nordisk A/S Mécanisme de libération activé par la respiration destiné à un dispositif de génération d'aérosol
ES2320955B1 (es) 2007-03-02 2010-03-16 Laboratorios Almirall S.A. Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida.
WO2008156586A2 (fr) * 2007-06-12 2008-12-24 Alkermes, Inc. Perfectionnements à des dispositifs inhalateurs de poudre
EP2042208A1 (fr) * 2007-09-25 2009-04-01 Boehringer Ingelheim Pharma GmbH & Co. KG Dispositif distributeur
DE102007053590A1 (de) * 2007-11-09 2009-05-14 Astra Zeneca Ab Handgerät zum Inhalieren von Substanzen
DE102007056263A1 (de) * 2007-11-22 2009-05-28 Siegfried Generics International Ag Dosiervorrichtung zur Inhalierung einer pulverförmigen Substanz
ES2320961B1 (es) 2007-11-28 2010-03-17 Laboratorios Almirall, S.A. Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor adrenergico beta2.
EP2217602B1 (fr) 2007-11-30 2018-08-29 Boehringer Ingelheim International GmbH Dérivés 1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one et leur utilisation comme modulateurs de pde9a pour le traitement de troubles cns
EP2534957B1 (fr) 2007-12-14 2015-05-27 AeroDesigns, Inc Administration de produits sous forme d'aérosols
EP2096105A1 (fr) * 2008-02-28 2009-09-02 Laboratorios Almirall, S.A. Dérivés de 4-(2-amino-1-hydroxyethyl)phénol en tant qu'antagonistes du récepteur adrénergique b2
EP2100598A1 (fr) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Composition à inhaler comprenant aclidinium pour le traitement de l'asthme et de maladies respiratoires obstructives chroniques
EP2100599A1 (fr) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Composition à inhaler comprenant aclidinium pour le traitement de l'asthme et de maladies respiratoires obstructives chroniques
UA105362C2 (en) 2008-04-02 2014-05-12 Бьорингер Ингельхайм Интернациональ Гмбх 1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators
EP2108641A1 (fr) 2008-04-11 2009-10-14 Laboratorios Almirall, S.A. Nouveaux dérivés substitués de spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one et leur utilisation comme ihibiteurs de p38 mitogen-activated kinase
EP2113503A1 (fr) 2008-04-28 2009-11-04 Laboratorios Almirall, S.A. Nouveaux dérivés d'indolin-2-one substitués et leur utilisation comme inhibiteurs de p38 mitogen-activated kinase
WO2010008523A1 (fr) 2008-07-13 2010-01-21 Map Pharmaceuticals, Inc. Procédés et appareil pour distribuer un médicament en aérosol
EA201100446A1 (ru) 2008-09-08 2011-10-31 Бёрингер Ингельхайм Интернациональ Гмбх Пиразолопиримидины и их применение для лечения нарушений цнс
US8109414B2 (en) * 2008-10-07 2012-02-07 Ing. Erich Pfeiffer Gmbh Discharge device
EP2196465A1 (fr) 2008-12-15 2010-06-16 Almirall, S.A. Dérivés de (3-oxo)pyridazin-4-ylurée comme inhibiteurs de PDE4
UY32297A (es) 2008-12-22 2010-05-31 Almirall Sa Sal mesilato de 5-(2-{[6-(2,2-difluoro-2-fenilitoxi) hexil]amino}-1-hidroxietil)-8-hidroxiquinolin-2( 1h)-ona como agonista del receptor b(beta)2 acrenérgico
EP2201977A1 (fr) * 2008-12-23 2010-06-30 Siegfried Generics International AG Dispositif de dosage destiné à la production d'un flux de gaz à l'aide d'une matière active répartie finement
EP2221297A1 (fr) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one et son utiisation dans le traitement de maladies des voies respiratoires
EP2221055A1 (fr) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one pour le traitement de la fonction pulmonaire
EP2226323A1 (fr) 2009-02-27 2010-09-08 Almirall, S.A. Nouveaux dérivés de tétrahydropyrazolo [3,4-c]isoquinoléine-5-amine
EP2228368A1 (fr) 2009-03-12 2010-09-15 Almirall, S.A. Procédé de fabrication de 5-(2-{[6-(2,2-difluoro-2-ph2nyl2thoxy)hexyl]amino}-1-hydroxy2thyl)-8-hydroxyquinolin-2(1h)-one
GEP20146098B (en) 2009-03-31 2014-05-27 Boehringer Ingelheim Int 1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their usage as pde9a modulators
EP2322176A1 (fr) 2009-11-11 2011-05-18 Almirall, S.A. Nouveaux dérivés de 7-phényl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
EP2380890A1 (fr) 2010-04-23 2011-10-26 Almirall, S.A. Nouveaux dérivés de 7,8-dihydro-1,6-naphthyridin-5(6h)-one comme PDE4 inhibiteurs
EP2386555A1 (fr) 2010-05-13 2011-11-16 Almirall, S.A. Nouveaux dérivés de cyclohéxylamine dotés d'activités agoniste bêta 2 adrénergique et antagoniste muscarinique m3
EP2394998A1 (fr) 2010-05-31 2011-12-14 Almirall, S.A. Dérivés de 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl en tant qu'inhibiteurs de la PDE4
CN103052639B (zh) 2010-08-12 2016-02-17 贝林格尔.英格海姆国际有限公司 6-环烷基-1,5-二氢-吡唑并[3,4-d]嘧啶-4-酮衍生物及其作为PDE9A抑制剂的用途
CN103079618B (zh) * 2010-09-06 2015-12-02 奇斯药制品公司 定量吸入器致动器、定量吸入器
EP2441755A1 (fr) 2010-09-30 2012-04-18 Almirall, S.A. Dérivés de pyridine et isoquinoline comme inhibiteurs des kinases Syk et JAK
EP2457900A1 (fr) 2010-11-25 2012-05-30 Almirall, S.A. Nouveaux dérivés de pyrazole présentant un comportement antagoniste CRTH2
EP2463289A1 (fr) 2010-11-26 2012-06-13 Almirall, S.A. Dérivés imidazo[1,2-b]pyridazine en tant qu'inhibiteur JAK
US8809345B2 (en) 2011-02-15 2014-08-19 Boehringer Ingelheim International Gmbh 6-cycloalkyl-pyrazolopyrimidinones for the treatment of CNS disorders
EP2489663A1 (fr) 2011-02-16 2012-08-22 Almirall, S.A. Composés en tant qu'inhibiteurs de la syk kinase
EP2510928A1 (fr) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium pour l'amélioration du sommeil des patients avec des maldadies respiratoires
EP2518071A1 (fr) 2011-04-29 2012-10-31 Almirall, S.A. Dérivés d'imidazopyridine en tant qu'inhibiteurs PI3K
EP2518070A1 (fr) 2011-04-29 2012-10-31 Almirall, S.A. Dérivés de pyrrolotriazinon en tant qu'inhibiteurs PI3K
EP2527344A1 (fr) 2011-05-25 2012-11-28 Almirall, S.A. Dérivés de pyridin-2(1h)-one utiles comme médicaments pour le traitement de maladies myeloproliferatives, de rejets de greffe, de maladies a médiation immune et de maladies inflammatoires
EP2526945A1 (fr) 2011-05-25 2012-11-28 Almirall, S.A. Nouveaux antagonistes de CRTH2
EP2548876A1 (fr) 2011-07-18 2013-01-23 Almirall, S.A. Nouveaux antagonistes de CRTH2
EP2548863A1 (fr) 2011-07-18 2013-01-23 Almirall, S.A. Nouveaux antagonistes de CRTH2
EP2554544A1 (fr) 2011-08-01 2013-02-06 Almirall, S.A. Dérivés de pyridin-2(1h)-one en tant qu'inhibiteurs de JAK
EP2578570A1 (fr) 2011-10-07 2013-04-10 Almirall, S.A. Nouveau procédé de fabrication de 5-(2-{[6-(2,2-difluoro-2-phényléthoxy)hexyl]amino}-1-hydroxyéthyl)-8-hydroxyquinolin-2(1h)-one via de nouveaux intermédiaires de synthèse
EP2592077A1 (fr) 2011-11-11 2013-05-15 Almirall, S.A. Nouveaux dérivés de cyclohéxylamine dotés d'activités agonistes bêta 2 adrénergique et antagoniste muscarinique M3
EP2592078A1 (fr) 2011-11-11 2013-05-15 Almirall, S.A. Nouveaux dérivés de cyclohéxylamine dotés d'activités agonistes bêta 2 adrénergique et antagoniste muscarinique M3
EP2641900A1 (fr) 2012-03-20 2013-09-25 Almirall, S.A. Nouvelles formes polymorphes de héminapadisylate de 5-(2-{[6-(2,2-difluoro-2-phényléthoxy) hexyl]amino}-1-(R)-hydroxyéthyl)-8-hydroxyquinolin-2(1h)-one en tant qu'agoniste du récepteur adrénergique ß2
EP2647627A1 (fr) 2012-04-02 2013-10-09 Almirall, S.A. Sels de 5-[(1r)-2-({2-[4-(2,2-difluoro-2-phényléthoxy)phényl]éthyl}amino)- 1-hydroxyéthyl]-8- hydroxyquinolin-2(1h)-one
EP2666465A1 (fr) 2012-05-25 2013-11-27 Almirall, S.A. Nouveau dosage et formule
EP2668941A1 (fr) 2012-05-31 2013-12-04 Almirall, S.A. Nouveau dosage et formulation d'abediterol
EP2874884A2 (fr) * 2012-07-20 2015-05-27 Sanofi SA Élément de dosage pour un dispositif d'inhalation et dispositif d'inhalation comprenant un élément de dosage
WO2014060431A1 (fr) 2012-10-16 2014-04-24 Almirall, S.A. Dérivés de pyrrolotriazinone en tant qu'inhibiteurs des pi3k
EP2738172A1 (fr) 2012-11-28 2014-06-04 Almirall, S.A. Nouveaux composés bicycliques utilisés comme modulateurs du canal crac
ES2750523T3 (es) 2012-12-18 2020-03-26 Almirall Sa Derivados de ciclohexil y quinuclidinil carbamato que tienen actividades de agonista beta2 adrenérgicos y antagonistas muscarínicos M3
AR094797A1 (es) 2013-02-15 2015-08-26 Almirall Sa Derivados de pirrolotriazina como inhibidores de pi3k
AR095222A1 (es) * 2013-04-03 2015-09-30 Sanofi Sa Elemento de medición para un dispositivo de inhalación y montaje para un dispositivo de inhalación que comprende un elemento de medición
EP2848615A1 (fr) 2013-07-03 2015-03-18 Almirall, S.A. Nouveaux dérivés de pyrazole utilisés comme modulateurs du canal CRAC
WO2015091285A1 (fr) 2013-12-19 2015-06-25 Almirall S.A. Formulation de dosage comprenant du salmétérol et du propionate de fluticasone
US10307550B2 (en) * 2014-06-09 2019-06-04 Dance Biopharm Inc. Liquid drug cartridges and associated dispenser
WO2016170009A1 (fr) 2015-04-21 2016-10-27 Almirall, S.A. Dérivés hétérocycliques amino-substitués utilisés comme inhibiteurs des canaux sodiques
WO2016202800A1 (fr) 2015-06-16 2016-12-22 Almirall, S.A. Dérivés de pyrrolotriazinone en tant qu'inhibiteurs de pi3k
WO2017076990A1 (fr) 2015-11-05 2017-05-11 Almirall, S.A. Sels d'addition de n-[4-(4-{[(1s)-1-(5-méthyl-4-oxo-3-phényl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)éthyl]amino}-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-1h-indol-6-yl]sulfamide
TW201919682A (zh) 2017-08-08 2019-06-01 西班牙商阿爾米雷爾有限公司 活化Ｎｒｆ２路徑的新穎化合物
CN109172978B (zh) * 2018-10-17 2024-07-02 河南省人民医院 智能可调式单向排气装置
EP3693044A1 (fr) * 2019-02-07 2020-08-12 Koninklijke Philips N.V. Inhalateurs actionnés par la respiration
WO2020148633A1 (fr) * 2019-01-14 2020-07-23 Philip Morris Products S.A. Inhalateur de poudre sèche
US20240016501A1 (en) * 2022-07-14 2024-01-18 Boston Scientific Scimed, Inc. Devices, assemblies, and methods for delivering agents

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2587215A (en) * 1949-04-27 1952-02-26 Frank P Priestly Inhalator
US2829642A (en) * 1954-10-18 1958-04-08 Melfy Frank A De Nebulizer having means for eliminating failures
US2992645A (en) * 1958-05-06 1961-07-18 Benger Lab Ltd Disperser for powders
US3636949A (en) * 1969-08-08 1972-01-25 Armstrong Kropp Dev Corp Inhalation-initiated aerosol dispenser
US3900138A (en) * 1972-08-07 1975-08-19 Minnesota Mining & Mfg Medicament dispenser
FR2224175B1 (fr) * 1973-04-04 1978-04-14 Isf Spa
GB1479283A (en) * 1973-07-23 1977-07-13 Bespak Industries Ltd Inhaler for powdered medicament
US4014336A (en) * 1975-01-13 1977-03-29 Syntex Puerto Rico, Inc. Inhalation device
FR2299011A1 (fr) * 1975-01-29 1976-08-27 Obert Jean Claude Generateur d'aerosols de part
SE411705B (sv) * 1976-11-09 1980-02-04 Draco Ab Anordning for generering av en avskermad, vesentligen drivmedelsfri aerosol
DE2726934A1 (de) * 1977-06-15 1979-01-04 Wokoeck Hans Dieter Vorrichtung zur feinverteilten gleichmaessigen bedeckung eines unregelmaessig gestalteten gegenstandes
US4274403A (en) * 1979-08-29 1981-06-23 Struve Roger L Inhaler
DE3040641A1 (de) * 1980-10-29 1982-05-27 C.H. Boehringer Sohn, 6507 Ingelheim Mundrohr fuer dosieraerosol-geraete
SE438261B (sv) * 1981-07-08 1985-04-15 Draco Ab Anvendning i dosinhalator av ett perforerat membran
FR2516387A1 (fr) * 1981-11-16 1983-05-20 Fabre Sa Pierre Inhalateur liberant des quantites pre-dosees de principe actif volatil ou entrainable par un excipient volatil contenu dans des microcapsules reparties periodiquement sur un support, ainsi que ledit support et son procede de fabrication
US4570630A (en) * 1983-08-03 1986-02-18 Miles Laboratories, Inc. Medicament inhalation device
FI69963C (fi) * 1984-10-04 1986-09-12 Orion Yhtymae Oy Doseringsanordning
US4803978A (en) * 1985-08-09 1989-02-14 Johnson Iv John J Apparatus for actuating an inhaler
FR2598918B1 (fr) * 1986-05-23 1988-08-05 Lille Ii Universite Droit Sant Dispositif permettant l'insufflation dans les voies respiratoires d'une poudre radio-opaque a l'etat finement divise
GB8804069D0 (en) * 1988-02-22 1988-03-23 Britains Petite Ltd Dispensers for powdered medication
ES2051371T3 (es) * 1988-10-04 1994-06-16 Univ Johns Hopkins Inhalador de aerosoles.
DK479189D0 (da) * 1989-01-06 1989-09-28 Hans Gernot Schenk Inhalator
IT1230313B (it) * 1989-07-07 1991-10-18 Somova Spa Inalatore per medicamenti in capsule.

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840279A (en) * 1995-06-21 1998-11-24 Asta Medica Aktiengesellschaft Pharmaceutical powder cartridge with integrated metering device and inhaler for powdered medicaments
US6071498A (en) * 1995-06-21 2000-06-06 Asta Medica Aktiengesellschaft Inhaler for powdered medicaments
US7954492B2 (en) 2002-01-24 2011-06-07 Almirall, S.A. Pharmaceutical powder cartridge, and inhaler equipped with same
EP1616592A1 (fr) 2004-07-16 2006-01-18 Sofotec GmbH & Co. KG Inhalateur pour l'administration des composés pharmaceutiques en poudre, et cartouche de poudre utilisée avec cet inhalateur

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LT3125B (en) 1994-12-27
EP0549605A1 (fr) 1993-07-07
ATE116558T1 (de) 1995-01-15
LTIP332A (lt) 1994-08-25
IE71162B1 (en) 1997-01-29
PL166852B1 (pl) 1995-06-30
SK13193A3 (en) 1993-07-07
HU213661B (en) 1997-09-29
JPH06500242A (ja) 1994-01-13
CZ281264B6 (cs) 1996-07-17
AU8339891A (en) 1992-03-30
DK0549605T3 (da) 1995-03-13
HU9300558D0 (en) 1993-06-28
JP2505339B2 (ja) 1996-06-05
LV10398B (en) 1996-06-20
EE03092B1 (et) 1998-06-15
KR930702037A (ko) 1993-09-08
FI930845A0 (fi) 1993-02-25
NZ239530A (en) 1994-12-22
AU654499B2 (en) 1994-11-10
CA2090227C (fr) 2004-11-30
US5617845A (en) 1997-04-08
CA2090227A1 (fr) 1992-03-01
CZ27893A3 (en) 1993-07-14
DE4027391A1 (de) 1992-03-12
EP0549605B1 (fr) 1995-01-04
SK278886B6 (sk) 1998-04-08
IL99285A (en) 1995-12-31
DE59104168D1 (de) 1995-02-16
WO1992004068A1 (fr) 1992-03-19
ES2066463T3 (es) 1995-03-01
NO930707D0 (no) 1993-02-26
LV10398A (lv) 1995-02-20
RU2098144C1 (ru) 1997-12-10
FI930845A (fi) 1993-02-25
IE913052A1 (en) 1992-03-11
NO930707L (no) 1993-02-26
GR3015540T3 (en) 1995-06-30
NO304353B1 (no) 1998-12-07
HUT66984A (en) 1995-01-30
KR0179376B1 (ko) 1999-04-01
FI105078B (fi) 2000-06-15

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