ZA916581B - Heterocyclic compounds and their preparation and use - Google Patents
Heterocyclic compounds and their preparation and useInfo
- Publication number
- ZA916581B ZA916581B ZA916581A ZA916581A ZA916581B ZA 916581 B ZA916581 B ZA 916581B ZA 916581 A ZA916581 A ZA 916581A ZA 916581 A ZA916581 A ZA 916581A ZA 916581 B ZA916581 B ZA 916581B
- Authority
- ZA
- South Africa
- Prior art keywords
- preparation
- compounds
- heterocyclic compounds
- forebrain
- hippocampus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Lubricants (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK198590A DK198590D0 (da) | 1990-08-21 | 1990-08-21 | Heterocykliske forbindelser, deres fremstilling og anvendelse |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA916581B true ZA916581B (en) | 1992-05-27 |
Family
ID=8109272
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA916581A ZA916581B (en) | 1990-08-21 | 1991-08-20 | Heterocyclic compounds and their preparation and use |
Country Status (23)
Country | Link |
---|---|
US (1) | US5260314A (fr) |
EP (1) | EP0544779B1 (fr) |
JP (1) | JP3100160B2 (fr) |
KR (1) | KR100247121B1 (fr) |
AT (1) | ATE174027T1 (fr) |
AU (1) | AU662105B2 (fr) |
CA (1) | CA2089769C (fr) |
CZ (1) | CZ282606B6 (fr) |
DE (1) | DE69130570T2 (fr) |
DK (2) | DK198590D0 (fr) |
ES (1) | ES2124707T3 (fr) |
FI (1) | FI930747A (fr) |
GR (1) | GR3029289T3 (fr) |
HU (2) | HU221433B (fr) |
IE (1) | IE912960A1 (fr) |
IL (1) | IL99165A (fr) |
NO (1) | NO301883B1 (fr) |
NZ (1) | NZ239450A (fr) |
PT (1) | PT98736B (fr) |
SG (1) | SG68567A1 (fr) |
SK (1) | SK283219B6 (fr) |
WO (1) | WO1992003433A1 (fr) |
ZA (1) | ZA916581B (fr) |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5527813A (en) * | 1990-08-21 | 1996-06-18 | Novo Nordisk A/S | Heterocyclic compounds and their preparation and use |
US5418240A (en) * | 1990-08-21 | 1995-05-23 | Novo Nordisk A/S | Heterocyclic compounds and their preparation and use |
US5641791A (en) * | 1991-08-13 | 1997-06-24 | Novo Nordisk A.S | Heterocyclic compounds and their preparation and use |
WO1993014089A1 (fr) * | 1992-01-13 | 1993-07-22 | Novo Nordisk A/S | Composes heterocycliques, leur preparation et leur utilisation |
MX9300875A (es) | 1992-02-20 | 1993-08-31 | Smithkline Beecham Plc | Procedimiento para la preparacion de compuestos azabiciclicos. |
AU671163B2 (en) * | 1992-12-23 | 1996-08-15 | Neurosearch A/S | Alkyl substituted heterocyclic compounds |
US5554626A (en) * | 1992-12-23 | 1996-09-10 | Neurosearch A/S | Substituted heterocyclic compounds as dopamine-reuptake inhibitors |
AU672052B2 (en) * | 1992-12-23 | 1996-09-19 | Neurosearch A/S | Antidepressant and antiparkinsonian compounds |
AU672644B2 (en) * | 1992-12-23 | 1996-10-10 | Neurosearch A/S | Aryl substituted heterocyclic compounds |
US6265419B1 (en) | 1993-12-21 | 2001-07-24 | Novo Nordisk A/S | Method of treating gastrointestinal motility disorders |
US6281232B1 (en) | 1993-08-19 | 2001-08-28 | Novo Nordisk A/S | Method of treating gastrointestinal motility disorders |
US5663182A (en) * | 1993-08-19 | 1997-09-02 | Bymaster; Franklin Porter | Antipsychotic method |
UA43347C2 (uk) * | 1993-08-19 | 2001-12-17 | Ново Нордіск А/С | Спосіб лікування психічних захворювань |
GB9409705D0 (en) * | 1994-05-14 | 1994-07-06 | Smithkline Beecham Plc | Novel compounds |
US5605908A (en) * | 1994-10-24 | 1997-02-25 | Eli Lilly And Company | Heterocyclic compounds and their use |
US5998404A (en) * | 1994-10-24 | 1999-12-07 | Eli Lilly And Company | Heterocyclic compounds and their use |
US5821370A (en) * | 1994-10-24 | 1998-10-13 | Eli Lilly And Company | Heterocyclic compounds and their preparation and use |
US5726193A (en) * | 1994-10-31 | 1998-03-10 | Eli Lilly And Company | Method for treating anxiety |
US5574028A (en) * | 1994-10-31 | 1996-11-12 | Eli Lilly And Company | Method for treating anxiety |
US5484794A (en) * | 1994-11-09 | 1996-01-16 | Eli Lilly And Company | Method for treating anxiety |
US5488056A (en) * | 1994-10-31 | 1996-01-30 | Eli Lilly And Company | Method for treating anxiety |
US5612351A (en) * | 1994-11-08 | 1997-03-18 | Novo Nordisk A/S | Method of treating urinary bladder dysfunctions |
TW390883B (en) * | 1994-11-21 | 2000-05-21 | Novo Nordisk As | Azacyclic or azabicyclic compounds for treating diseases in the central nervous system, their preparation and pharmaceutical composition thereof |
TW304167B (fr) * | 1995-01-30 | 1997-05-01 | Lilly Co Eli | |
JPH11500113A (ja) * | 1995-02-17 | 1999-01-06 | ノボ ノルディスク アクティーゼルスカブ | ヘテロ環化合物類の使用 |
PE17897A1 (es) * | 1995-02-17 | 1997-06-12 | Lilly Co Eli | Formulacion transdermica en parche del 3-(4-butiltio)-1,2,5-tiadiazol-3-il)-1-azabiciclo (2,2,2) octano |
US5767280A (en) * | 1995-06-01 | 1998-06-16 | Eli Lilly And Company | Process for making heterocyclic compounds |
US6040442A (en) * | 1995-06-01 | 2000-03-21 | Eli Lilly And Company | Process for preparing 1,2,5-thiadiazole containing ethers |
ATE362931T1 (de) * | 1995-10-13 | 2007-06-15 | Neurosearch As | 8-azabicyclo(3.2.1)oct-2en-derivate, deren herstellung und anwendung |
US5852037A (en) * | 1995-11-13 | 1998-12-22 | Eli Lilly And Company | Method for treating anxiety |
US5889019A (en) * | 1995-11-29 | 1999-03-30 | Eli Lilly And Company | Heterocyclic compounds and their use |
WO1997019669A2 (fr) * | 1995-11-29 | 1997-06-05 | Eli Lilly And Company | Composes heterocycliques et leur utilisation |
AU1128297A (en) * | 1995-12-06 | 1997-06-27 | Eli Lilly And Company | Composition for treating pain |
EA199800535A1 (ru) * | 1995-12-07 | 1998-12-24 | Эли Лилли Энд Компани | Способ лечения боли |
WO1997025043A1 (fr) * | 1996-01-04 | 1997-07-17 | Novo Nordisk A/S | Procede de traitement de l'hypercholesterolemie et des troubles apparentes |
EP0888355A1 (fr) * | 1996-03-19 | 1999-01-07 | Novo Nordisk A/S | Composes heterocycliques, leur preparation et leur utilisation |
US5914338A (en) * | 1996-04-02 | 1999-06-22 | Novo Nordisk | Heterocyclic compounds and their preparation and use |
CA2250472A1 (fr) * | 1996-04-23 | 1997-10-30 | Steven James Quimby | Composes heterocycliques |
CA2252527A1 (fr) * | 1996-04-23 | 1997-10-30 | Lone Jeppesen | Composes heterocycliques |
AU2679497A (en) * | 1996-04-23 | 1997-11-12 | Eli Lilly And Company | Heterocyclic compounds |
JP2000509046A (ja) * | 1996-04-23 | 2000-07-18 | イーライ・リリー・アンド・カンパニー | ヘテロサイクリック化合物群 |
DE69724967D1 (de) * | 1996-04-24 | 2003-10-23 | Novo Nordisk As | Heterozyklische verbindungen, ihre herstellung und ihre anwendung |
US5834458A (en) * | 1996-10-09 | 1998-11-10 | Eli Lilly And Company | Heterocyclic compounds and their use |
US5733912A (en) * | 1997-02-19 | 1998-03-31 | Abbott Laboratories | 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission |
GB9805557D0 (en) * | 1998-03-16 | 1998-05-13 | Merck Sharp & Dohme | A combination of therapeutic agents |
EP1406900B1 (fr) | 2001-07-06 | 2006-10-04 | Neurosearch A/S | Nouveaux composes, preparation et utilisation de ces derniers |
CA2620333A1 (fr) * | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenese par modulation du recepteur muscarinique |
EP2258358A3 (fr) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenèse avec un inhibiteur de l'acetylcholinestérase |
EP1940389A2 (fr) | 2005-10-21 | 2008-07-09 | Braincells, Inc. | Modulation de la neurogenese par inhibition de la pde |
CA2625210A1 (fr) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Modulation de la neurogenese dont la mediation est assuree par recepteur gaba |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
AU2007249399A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
MX2008014320A (es) | 2006-05-09 | 2009-03-25 | Braincells Inc | Neurogenesis mediada por el receptor de 5-hidroxitriptamina. |
MX2009002496A (es) * | 2006-09-08 | 2009-07-10 | Braincells Inc | Combinaciones que contienen un derivado de 4-acilaminopiridina. |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ219646A (en) * | 1986-03-27 | 1990-10-26 | Merck Sharp & Dohme | Oxadiazole derivatives of azacyclics for treating cns disorders |
GB8610432D0 (en) * | 1986-04-29 | 1986-06-04 | Akzo Nv | Amino-thiazole & oxazole derivatives |
GB8714789D0 (en) * | 1987-06-24 | 1987-07-29 | Lundbeck & Co As H | Heterocyclic compounds |
GB8717446D0 (en) * | 1987-07-23 | 1987-08-26 | Merck Sharp & Dohme | Chemical compounds |
NZ225999A (en) * | 1987-09-10 | 1992-04-28 | Merck Sharp & Dohme | Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions |
IL88156A (en) * | 1987-11-13 | 1997-02-18 | Novo Nordisk As | Azacyclic compounds their preparation and pharmaceutical compositions containing them |
EP0322182A3 (fr) * | 1987-12-22 | 1992-01-02 | Beecham Group Plc | Composés azabicycliques, procédé pour leur préparation et compositions pharmaceutiques les contenant |
IL88846A0 (en) * | 1988-01-08 | 1989-07-31 | Merck Sharp & Dohme | Lipophilic oxadiazoles,their preparation and pharmaceutical compositions containing them |
NZ227841A (en) * | 1988-02-12 | 1991-08-27 | Merck Sharp & Dohme | Heterocyclic compounds with at least two non-condensed five membered rings and pharmaceutical compositions |
DK162892C (da) * | 1988-07-04 | 1992-05-11 | Novo Nordisk As | 1,2,5,6-tetrahydropyridinforbindelser, deres fremstilling og farmaceutiske praeparater indeholdende disse |
US5043345A (en) * | 1989-02-22 | 1991-08-27 | Novo Nordisk A/S | Piperidine compounds and their preparation and use |
-
1990
- 1990-08-21 DK DK198590A patent/DK198590D0/da not_active Application Discontinuation
-
1991
- 1991-08-12 IL IL99165A patent/IL99165A/xx not_active IP Right Cessation
- 1991-08-13 US US07/744,160 patent/US5260314A/en not_active Expired - Lifetime
- 1991-08-19 NZ NZ239450A patent/NZ239450A/en not_active IP Right Cessation
- 1991-08-20 JP JP03513857A patent/JP3100160B2/ja not_active Expired - Fee Related
- 1991-08-20 CZ CS93244A patent/CZ282606B6/cs not_active IP Right Cessation
- 1991-08-20 SG SG1996005511A patent/SG68567A1/en unknown
- 1991-08-20 AT AT91915629T patent/ATE174027T1/de not_active IP Right Cessation
- 1991-08-20 AU AU84036/91A patent/AU662105B2/en not_active Ceased
- 1991-08-20 CA CA002089769A patent/CA2089769C/fr not_active Expired - Fee Related
- 1991-08-20 ZA ZA916581A patent/ZA916581B/xx unknown
- 1991-08-20 ES ES91915629T patent/ES2124707T3/es not_active Expired - Lifetime
- 1991-08-20 KR KR1019930700496A patent/KR100247121B1/ko not_active IP Right Cessation
- 1991-08-20 DE DE69130570T patent/DE69130570T2/de not_active Expired - Fee Related
- 1991-08-20 HU HU9300464A patent/HU221433B/hu unknown
- 1991-08-20 SK SK127-93A patent/SK283219B6/sk unknown
- 1991-08-20 WO PCT/DK1991/000236 patent/WO1992003433A1/fr active IP Right Grant
- 1991-08-20 DK DK91915629T patent/DK0544779T3/da active
- 1991-08-20 EP EP91915629A patent/EP0544779B1/fr not_active Expired - Lifetime
- 1991-08-21 PT PT98736A patent/PT98736B/pt not_active IP Right Cessation
- 1991-08-21 IE IE296091A patent/IE912960A1/en not_active IP Right Cessation
-
1993
- 1993-02-19 FI FI930747A patent/FI930747A/fi not_active Application Discontinuation
- 1993-02-19 NO NO930601A patent/NO301883B1/no unknown
-
1995
- 1995-06-29 HU HU95P/P00608P patent/HU211861A9/hu unknown
-
1999
- 1999-02-03 GR GR990400369T patent/GR3029289T3/el unknown
Also Published As
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