DK198590D0 - Heterocykliske forbindelser, deres fremstilling og anvendelse - Google Patents

Heterocykliske forbindelser, deres fremstilling og anvendelse

Info

Publication number
DK198590D0
DK198590D0 DK198590A DK198590A DK198590D0 DK 198590 D0 DK198590 D0 DK 198590D0 DK 198590 A DK198590 A DK 198590A DK 198590 A DK198590 A DK 198590A DK 198590 D0 DK198590 D0 DK 198590D0
Authority
DK
Denmark
Prior art keywords
preparation
compounds
heterocyclic compounds
forebrain
hippocampus
Prior art date
Application number
DK198590A
Other languages
Danish (da)
English (en)
Inventor
Per Sauerberg
Preben H Olesen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Priority to DK198590A priority Critical patent/DK198590D0/da
Publication of DK198590D0 publication Critical patent/DK198590D0/da
Priority to IL99165A priority patent/IL99165A/xx
Priority to US07/744,160 priority patent/US5260314A/en
Priority to NZ239450A priority patent/NZ239450A/en
Priority to ZA916581A priority patent/ZA916581B/xx
Priority to JP03513857A priority patent/JP3100160B2/ja
Priority to SG1996005511A priority patent/SG68567A1/en
Priority to AT91915629T priority patent/ATE174027T1/de
Priority to EP91915629A priority patent/EP0544779B1/fr
Priority to KR1019930700496A priority patent/KR100247121B1/ko
Priority to AU84036/91A priority patent/AU662105B2/en
Priority to CA002089769A priority patent/CA2089769C/fr
Priority to DK91915629T priority patent/DK0544779T3/da
Priority to ES91915629T priority patent/ES2124707T3/es
Priority to DE69130570T priority patent/DE69130570T2/de
Priority to SK127-93A priority patent/SK283219B6/sk
Priority to PCT/DK1991/000236 priority patent/WO1992003433A1/fr
Priority to CS93244A priority patent/CZ282606B6/cs
Priority to HU9300464A priority patent/HU221433B/hu
Priority to IE296091A priority patent/IE912960A1/en
Priority to PT98736A priority patent/PT98736B/pt
Priority to FI930747A priority patent/FI930747A/fi
Priority to NO930601A priority patent/NO301883B1/no
Priority to US08/026,943 priority patent/US5418240A/en
Priority to US08/204,832 priority patent/US5527813A/en
Priority to US08/450,838 priority patent/US5578602A/en
Priority to HU95P/P00608P priority patent/HU211861A9/hu
Priority to GR990400369T priority patent/GR3029289T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Lubricants (AREA)
  • Hydrogenated Pyridines (AREA)
DK198590A 1990-08-21 1990-08-21 Heterocykliske forbindelser, deres fremstilling og anvendelse DK198590D0 (da)

Priority Applications (28)

Application Number Priority Date Filing Date Title
DK198590A DK198590D0 (da) 1990-08-21 1990-08-21 Heterocykliske forbindelser, deres fremstilling og anvendelse
IL99165A IL99165A (en) 1990-08-21 1991-08-12 Azabicycloalkane (and alkene) derivatives of 1,2,5-oxa- and thiadiazoles, their preparation and pharmaceutical compositions containing them
US07/744,160 US5260314A (en) 1990-08-21 1991-08-13 Certain 3-(1,2,5-oxa- or thiadiazol-4-yl)-1-azabicyclo [2.2.2]octanes having pharmaceutical properties
NZ239450A NZ239450A (en) 1990-08-21 1991-08-19 Azabicyclic substituted thiadiazole or oxadiazole derivatives and pharmaceutical compositions
HU9300464A HU221433B (en) 1990-08-21 1991-08-20 Oxadiazole and tiadiazole derivatives, process for their preparation and pharmaceutical compositions containing them
DK91915629T DK0544779T3 (da) 1990-08-21 1991-08-20 Heterocykliske forbindelser og deres fremstilling og anvendelse
SK127-93A SK283219B6 (sk) 1990-08-21 1991-08-20 Substituované 1,2,5-tia- a oxadiazol-4-yl-1-azabicyklické zlúčeniny, spôsob ich prípravy, použitie a farmaceutický prostriedok
SG1996005511A SG68567A1 (en) 1990-08-21 1991-08-20 Heterocyclic compounds and their preparation and use
AT91915629T ATE174027T1 (de) 1990-08-21 1991-08-20 Heterozyklische verbindungen, ihre herstellung und anwendung
EP91915629A EP0544779B1 (fr) 1990-08-21 1991-08-20 Composes heterocycliques, preparation et utilisation de ceux-ci
KR1019930700496A KR100247121B1 (ko) 1990-08-21 1991-08-20 헤테로시클릭 화합물과 그의 제조방법 및 용도
AU84036/91A AU662105B2 (en) 1990-08-21 1991-08-20 Derivatives and azabicyclic oxadiazole or thiadiazole compounds
CA002089769A CA2089769C (fr) 1990-08-21 1991-08-20 Composes heterocycliques, leur preparation et leur utilisation
ZA916581A ZA916581B (en) 1990-08-21 1991-08-20 Heterocyclic compounds and their preparation and use
ES91915629T ES2124707T3 (es) 1990-08-21 1991-08-20 Compuestos heterociclicos y su preparacion y utilizacion.
DE69130570T DE69130570T2 (de) 1990-08-21 1991-08-20 Heterozyklische verbindungen, ihre herstellung und anwendung
JP03513857A JP3100160B2 (ja) 1990-08-21 1991-08-20 複素環式化合物、その調製方法およびその用途
PCT/DK1991/000236 WO1992003433A1 (fr) 1990-08-21 1991-08-20 Composes heterocycliques, preparation et utilisation de ceux-ci
CS93244A CZ282606B6 (cs) 1990-08-21 1991-08-20 Heterocyklické sloučeniny, způsob jejich přípravy a použití
PT98736A PT98736B (pt) 1990-08-21 1991-08-21 Processo de preparacao de compostos de piperidina e de composicoes farmaceuticas que os contem
IE296091A IE912960A1 (en) 1990-08-21 1991-08-21 Heterocyclic compounds and their preparation and use
FI930747A FI930747A (fi) 1990-08-21 1993-02-19 Heterocykliska foereningar och deras framstaellning och anvaendning
NO930601A NO301883B1 (no) 1990-08-21 1993-02-19 Analogifremgangsmåte ved fremstilling av heterocykliske forbindelser
US08/026,943 US5418240A (en) 1990-08-21 1993-03-05 Heterocyclic compounds and their preparation and use
US08/204,832 US5527813A (en) 1990-08-21 1994-03-02 Heterocyclic compounds and their preparation and use
US08/450,838 US5578602A (en) 1990-08-21 1995-05-25 Certain 1-azabicyclo[3.3.1]nonene derivatives and their pharmacological uses
HU95P/P00608P HU211861A9 (en) 1990-08-21 1995-06-29 Heterocyclic compounds and their preparation and use
GR990400369T GR3029289T3 (en) 1990-08-21 1999-02-03 Heterocyclic compounds and their preparation and use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK198590A DK198590D0 (da) 1990-08-21 1990-08-21 Heterocykliske forbindelser, deres fremstilling og anvendelse

Publications (1)

Publication Number Publication Date
DK198590D0 true DK198590D0 (da) 1990-08-21

Family

ID=8109272

Family Applications (2)

Application Number Title Priority Date Filing Date
DK198590A DK198590D0 (da) 1990-08-21 1990-08-21 Heterocykliske forbindelser, deres fremstilling og anvendelse
DK91915629T DK0544779T3 (da) 1990-08-21 1991-08-20 Heterocykliske forbindelser og deres fremstilling og anvendelse

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK91915629T DK0544779T3 (da) 1990-08-21 1991-08-20 Heterocykliske forbindelser og deres fremstilling og anvendelse

Country Status (23)

Country Link
US (1) US5260314A (fr)
EP (1) EP0544779B1 (fr)
JP (1) JP3100160B2 (fr)
KR (1) KR100247121B1 (fr)
AT (1) ATE174027T1 (fr)
AU (1) AU662105B2 (fr)
CA (1) CA2089769C (fr)
CZ (1) CZ282606B6 (fr)
DE (1) DE69130570T2 (fr)
DK (2) DK198590D0 (fr)
ES (1) ES2124707T3 (fr)
FI (1) FI930747A (fr)
GR (1) GR3029289T3 (fr)
HU (2) HU221433B (fr)
IE (1) IE912960A1 (fr)
IL (1) IL99165A (fr)
NO (1) NO301883B1 (fr)
NZ (1) NZ239450A (fr)
PT (1) PT98736B (fr)
SG (1) SG68567A1 (fr)
SK (1) SK283219B6 (fr)
WO (1) WO1992003433A1 (fr)
ZA (1) ZA916581B (fr)

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US5527813A (en) * 1990-08-21 1996-06-18 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
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WO1993014089A1 (fr) * 1992-01-13 1993-07-22 Novo Nordisk A/S Composes heterocycliques, leur preparation et leur utilisation
MX9300875A (es) 1992-02-20 1993-08-31 Smithkline Beecham Plc Procedimiento para la preparacion de compuestos azabiciclicos.
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AU672644B2 (en) * 1992-12-23 1996-10-10 Neurosearch A/S Aryl substituted heterocyclic compounds
US6265419B1 (en) * 1993-12-21 2001-07-24 Novo Nordisk A/S Method of treating gastrointestinal motility disorders
US5663182A (en) * 1993-08-19 1997-09-02 Bymaster; Franklin Porter Antipsychotic method
US6271229B1 (en) 1993-08-19 2001-08-07 Novo Nordisk A/S Method of treating gastrointestinal motility disorders
DE69427537T2 (de) * 1993-08-19 2002-04-04 Novo Nordisk A/S, Bagsvaerd Antipsychotisches verfahren mit thiadiazol- und oxadiazol-derivaten
GB9409705D0 (en) * 1994-05-14 1994-07-06 Smithkline Beecham Plc Novel compounds
US5998404A (en) * 1994-10-24 1999-12-07 Eli Lilly And Company Heterocyclic compounds and their use
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US5889019A (en) * 1995-11-29 1999-03-30 Eli Lilly And Company Heterocyclic compounds and their use
WO1997020819A1 (fr) * 1995-12-06 1997-06-12 Eli Lilly And Company Compositions de traitement de la douleur
NZ324594A (en) * 1995-12-07 1999-09-29 Lilly Co Eli A method and composition for treating pain using a composition comprising an azacyclic azabicyclic or tetrahydropyridine compound and an analgesic
WO1997025043A1 (fr) * 1996-01-04 1997-07-17 Novo Nordisk A/S Procede de traitement de l'hypercholesterolemie et des troubles apparentes
CA2248153A1 (fr) * 1996-03-19 1997-09-25 Novo Nordisk A/S Composes heterocycliques, leur preparation et leur utilisation
US5914338A (en) * 1996-04-02 1999-06-22 Novo Nordisk Heterocyclic compounds and their preparation and use
JP2000509044A (ja) * 1996-04-23 2000-07-18 イーライ・リリー・アンド・カンパニー ヘテロサイクリック化合物群
EP0900219A4 (fr) * 1996-04-23 2001-05-23 Lilly Co Eli Composes heterocycliques
ATE221066T1 (de) * 1996-04-23 2002-08-15 Lilly Co Eli Heterozyklische verbindungen
AU2991397A (en) * 1996-04-23 1997-11-12 Eli Lilly And Company Heterocyclic compounds
WO1997040045A1 (fr) * 1996-04-24 1997-10-30 Novo Nordisk A/S Composes heterocycliques, preparation et utilisation
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US5733912A (en) * 1997-02-19 1998-03-31 Abbott Laboratories 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
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US7678363B2 (en) * 2005-08-26 2010-03-16 Braincells Inc Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs
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Also Published As

Publication number Publication date
JP3100160B2 (ja) 2000-10-16
CZ24493A3 (en) 1994-01-19
DE69130570T2 (de) 1999-04-29
EP0544779B1 (fr) 1998-12-02
EP0544779A1 (fr) 1993-06-09
JPH06500542A (ja) 1994-01-20
IL99165A0 (en) 1992-07-15
FI930747A0 (fi) 1993-02-19
AU8403691A (en) 1992-03-17
IE912960A1 (en) 1992-02-26
WO1992003433A1 (fr) 1992-03-05
SG68567A1 (en) 1999-11-16
AU662105B2 (en) 1995-08-24
CA2089769A1 (fr) 1992-02-22
HU221433B (en) 2002-10-28
NZ239450A (en) 1994-12-22
ZA916581B (en) 1992-05-27
NO930601L (no) 1993-04-16
DK0544779T3 (da) 1999-08-16
KR100247121B1 (ko) 2000-08-01
HUT66863A (en) 1995-01-30
ES2124707T3 (es) 1999-02-16
GR3029289T3 (en) 1999-05-28
NO301883B1 (no) 1997-12-22
HU211861A9 (en) 1995-12-28
NO930601D0 (no) 1993-02-19
CZ282606B6 (cs) 1997-08-13
IL99165A (en) 1997-11-20
CA2089769C (fr) 2002-10-01
PT98736A (pt) 1992-07-31
DE69130570D1 (de) 1999-01-14
PT98736B (pt) 1999-01-29
ATE174027T1 (de) 1998-12-15
SK12793A3 (en) 1993-09-09
HU9300464D0 (en) 1993-05-28
FI930747A (fi) 1993-03-30
SK283219B6 (sk) 2003-03-04
US5260314A (en) 1993-11-09

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