ZA912935B - Antiinflammatory hydroxamic acids and n-hydroxyureas - Google Patents
Antiinflammatory hydroxamic acids and n-hydroxyureasInfo
- Publication number
- ZA912935B ZA912935B ZA912935A ZA912935A ZA912935B ZA 912935 B ZA912935 B ZA 912935B ZA 912935 A ZA912935 A ZA 912935A ZA 912935 A ZA912935 A ZA 912935A ZA 912935 B ZA912935 B ZA 912935B
- Authority
- ZA
- South Africa
- Prior art keywords
- hydroxyureas
- antiinflammatory
- hydroxamic acids
- sulfur
- oxygen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03G—ELECTROGRAPHY; ELECTROPHOTOGRAPHY; MAGNETOGRAPHY
- G03G15/00—Apparatus for electrographic processes using a charge pattern
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/64—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups singly-bound to oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/64—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- General Physics & Mathematics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Cardiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Treating Waste Gases (AREA)
- Projection Apparatus (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10504890 | 1990-04-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA912935B true ZA912935B (en) | 1992-11-25 |
Family
ID=14397114
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA912935A ZA912935B (en) | 1990-04-20 | 1991-04-19 | Antiinflammatory hydroxamic acids and n-hydroxyureas |
Country Status (29)
Country | Link |
---|---|
US (1) | US5256789A (de) |
EP (1) | EP0525111B1 (de) |
JP (1) | JPH075560B2 (de) |
KR (1) | KR900016822A (de) |
CN (1) | CN1033325C (de) |
AT (1) | ATE123764T1 (de) |
AU (1) | AU646865B2 (de) |
BR (1) | BR9106367A (de) |
CA (1) | CA2078216A1 (de) |
CS (1) | CS110491A3 (de) |
DE (1) | DE69110460T2 (de) |
DK (1) | DK0525111T3 (de) |
EG (1) | EG19608A (de) |
ES (1) | ES2073755T3 (de) |
FI (1) | FI924725A0 (de) |
GR (1) | GR3017078T3 (de) |
HU (1) | HUT61723A (de) |
IE (1) | IE66530B1 (de) |
IL (1) | IL97866A (de) |
MY (1) | MY106510A (de) |
NO (1) | NO180482C (de) |
NZ (1) | NZ237884A (de) |
PL (1) | PL165843B1 (de) |
PT (1) | PT97422A (de) |
RU (1) | RU2108324C1 (de) |
TW (1) | TW206221B (de) |
WO (1) | WO1991016298A1 (de) |
YU (1) | YU48329B (de) |
ZA (1) | ZA912935B (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9002375D0 (en) * | 1990-02-02 | 1990-04-04 | Pfizer Ltd | Triazole antifungal agents |
WO1991014674A2 (en) * | 1990-03-27 | 1991-10-03 | Smithkline Beecham Corporation | 5-lipoxygenase inhibitors |
US5260316A (en) * | 1991-07-30 | 1993-11-09 | Ciba-Geigy Corporation | Isoquinolyl substituted hydroxylamine derivatives |
US5334600A (en) * | 1991-07-30 | 1994-08-02 | Ciba-Geigy Corporation | Isoquinolyl substituted hydroxylamine derivatives |
US5350761A (en) * | 1991-07-30 | 1994-09-27 | Ciba-Geigy Corporation | Indolyl substituted hydroxylamine derivatives |
AU675784B2 (en) * | 1992-04-07 | 1997-02-20 | Merrell Dow Pharmaceuticals Inc. | Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans |
JP2661841B2 (ja) * | 1992-07-23 | 1997-10-08 | ファイザー製薬株式会社 | インドリン誘導体 |
JP3131225B2 (ja) | 1995-07-26 | 2001-01-31 | ファイザー・インコーポレーテッド | N−(アロイル)グリシンヒドロキサム酸誘導体および関連化合物 |
US7229986B2 (en) | 2000-05-16 | 2007-06-12 | Takeda Pharmaceutical Company Ltd. | Melanin-concentrating hormone antagonist |
CN101437524B (zh) * | 2004-09-14 | 2012-01-11 | 法莫赛特股份有限公司 | 2'-氟-2'-烷基-取代的或其它任选取代的呋喃核糖基嘧啶和嘌呤及其衍生物的制备 |
EP1807080A1 (de) * | 2004-10-29 | 2007-07-18 | AstraZeneca AB | Verwendung von ungesättigten chinolin- oder naphthalin-derivaten als medikamente |
FR2881137B1 (fr) * | 2005-01-27 | 2007-03-02 | Servier Lab | Nouveaux derives d'oximes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
JP4989648B2 (ja) * | 2005-08-03 | 2012-08-01 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 抗癌剤として有用なイルジン類似体 |
US8512464B2 (en) * | 2009-12-02 | 2013-08-20 | 3M Innovative Properties Company | Functionalized zirconia nanoparticles and high index films made therefrom |
JP2013526576A (ja) * | 2010-05-18 | 2013-06-24 | アメリカ合衆国 | ヒト12−リポキシゲナーゼ阻害剤 |
EP2661426B1 (de) | 2011-01-05 | 2014-08-27 | Syngenta Participations AG | Pyrazol-4-yl-carboxamidderivate als mikrobiozide |
WO2015074064A2 (en) | 2013-11-18 | 2015-05-21 | Bair Kenneth W | Tetrahydroquinoline compositions as bet bromodomain inhibitors |
US9422281B2 (en) | 2013-11-18 | 2016-08-23 | Forma Therapeutics, Inc. | Benzopiperazine compositions as BET bromodomain inhibitors |
CA3022432A1 (en) * | 2016-04-29 | 2017-11-02 | Board Of Regents, The University Of Texas System | Sigma receptor binders |
JP7098077B1 (ja) | 2021-10-04 | 2022-07-08 | 大日精化工業株式会社 | カーボン材料分散液の製造方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL78157A (en) * | 1985-03-16 | 1989-08-15 | Wellcome Found | Aryl derivatives,their preparation and pharmaceutical compositions containing them |
US4728670A (en) * | 1986-06-04 | 1988-03-01 | E. R. Squibb & Sons, Inc. | Biphenyl hydroxamic acids |
DE3882732T2 (de) * | 1987-02-10 | 1993-12-02 | Abbott Lab | Indol, Benzofuran, Benzothiophen enthaltende, Lipoxygenase hemmende Verbindungen. |
US4897422A (en) * | 1987-02-10 | 1990-01-30 | Abbott Laboratories | Lipoxygenase inhibiting compounds |
CA1336099C (en) * | 1987-04-24 | 1995-06-27 | James B. Summers, Jr. | Urea based lipoxygenase compounds |
US4822809A (en) * | 1987-11-13 | 1989-04-18 | Abbott Laboratories | Benzazole lipoxygenase inhibiting compounds |
DK418289A (da) * | 1989-08-24 | 1991-02-25 | Micro Matic As | Sikringssystem for anstikker |
-
1990
- 1990-04-23 KR KR1019900005669A patent/KR900016822A/ko not_active Application Discontinuation
-
1991
- 1991-03-01 JP JP3216711A patent/JPH075560B2/ja not_active Expired - Lifetime
- 1991-04-14 EG EG22591A patent/EG19608A/xx active
- 1991-04-16 IL IL97866A patent/IL97866A/xx not_active IP Right Cessation
- 1991-04-16 TW TW080102964A patent/TW206221B/zh active
- 1991-04-18 WO PCT/US1991/002674 patent/WO1991016298A1/en active IP Right Grant
- 1991-04-18 HU HU923286A patent/HUT61723A/hu unknown
- 1991-04-18 AU AU77986/91A patent/AU646865B2/en not_active Ceased
- 1991-04-18 DK DK91909090.2T patent/DK0525111T3/da active
- 1991-04-18 EP EP91909090A patent/EP0525111B1/de not_active Expired - Lifetime
- 1991-04-18 BR BR919106367A patent/BR9106367A/pt not_active Application Discontinuation
- 1991-04-18 CA CA002078216A patent/CA2078216A1/en not_active Abandoned
- 1991-04-18 RU RU92016453A patent/RU2108324C1/ru active
- 1991-04-18 PL PL91296500A patent/PL165843B1/pl unknown
- 1991-04-18 DE DE69110460T patent/DE69110460T2/de not_active Expired - Fee Related
- 1991-04-18 ES ES91909090T patent/ES2073755T3/es not_active Expired - Lifetime
- 1991-04-18 AT AT91909090T patent/ATE123764T1/de not_active IP Right Cessation
- 1991-04-18 CS CS911104A patent/CS110491A3/cs unknown
- 1991-04-19 CN CN91103231A patent/CN1033325C/zh not_active Expired - Fee Related
- 1991-04-19 MY MYPI91000653A patent/MY106510A/en unknown
- 1991-04-19 NZ NZ237884A patent/NZ237884A/xx unknown
- 1991-04-19 PT PT97422A patent/PT97422A/pt not_active Application Discontinuation
- 1991-04-19 YU YU71091A patent/YU48329B/sh unknown
- 1991-04-19 IE IE131091A patent/IE66530B1/en not_active IP Right Cessation
- 1991-04-19 ZA ZA912935A patent/ZA912935B/xx unknown
-
1992
- 1992-02-18 US US07/835,934 patent/US5256789A/en not_active Expired - Fee Related
- 1992-10-19 FI FI924725A patent/FI924725A0/fi unknown
- 1992-10-19 NO NO924045A patent/NO180482C/no unknown
-
1995
- 1995-08-09 GR GR950402206T patent/GR3017078T3/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL97866A0 (en) | Antiinflammatory hydroxamic acids and n-hydroxyureas | |
GB2303629A (en) | Metalloproteinase inhibitors | |
FI932249A0 (fi) | Dubbelverkande inhibitorer | |
FI941396A0 (fi) | Koostumuksia biologisesti aktiivisen TGF-valvottua vapauttamista varten | |
CA2255951A1 (en) | Substituted 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators | |
HK1003938A1 (en) | Thiazole derivatives as active oxygen inhibitors | |
MY128063A (en) | Aromatic heterocyclic compound as antiinflammatory agents | |
ZA919317B (en) | Novel hydroxamic acid and N-hydroxyurea derivatives and their use. | |
RU92016453A (ru) | Гидроксамовые кислоты и n-гидроксимочевины, способы их получения, фармацевтическая композиция и способ ингибирования липоксигеназы | |
CZ20013522A3 (cs) | Sloučeniny inhibující adhezi buněk vykazující protizánětlivé a imunosupresivní účinky | |
ATE227293T1 (de) | 2,3-disubstituierte-(5,6)-heteroarylkondensiert - pyrimidin-4-one | |
ZA911728B (en) | Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors | |
EP0310072A3 (de) | Nichtpeptide beta-Succinamidoacylaminodiole als antihypertensive Agenzien | |
EP0293751A3 (en) | Taurohyodeoxycholic acid for the therapy of calculosis of the biliary tract and of biliary dyspepsia | |
EP0313847A3 (de) | Nichtpeptide alpha-succinamidoacyl-Aminodiole als antihypertensive Agenzien | |
EA200000204A1 (ru) | Производные пирролопирролона в качестве ингибиторов эластазы нейтрофилов | |
CA2139731A1 (en) | 2-heterocyclic-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents | |
NZ322777A (en) | Sulfur containing di-tert-butylphenol compounds useful as anti-inflammatory agents | |
DK0561882T3 (da) | Hydroxamsyrederivater, som inhiberer lipoxygenase | |
DK0775692T3 (da) | Guanidinomethylcyclohexancarboxylsyreesterderivater | |
SE9902596D0 (sv) | Pharmaceutically active compounds | |
RU94019328A (ru) | α- ГЕТЕРОАРИЛОКСИМЕТИЛКЕТОНЫ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, ИНГИБИРУЮЩАЯ ИНТЕРЛЕЙКИН-1 - β -ПРОТЕАЗУ |