ZA909088B - Lipospheres for controlled delivery of substances - Google Patents

Lipospheres for controlled delivery of substances

Info

Publication number
ZA909088B
ZA909088B ZA909088A ZA909088A ZA909088B ZA 909088 B ZA909088 B ZA 909088B ZA 909088 A ZA909088 A ZA 909088A ZA 909088 A ZA909088 A ZA 909088A ZA 909088 B ZA909088 B ZA 909088B
Authority
ZA
South Africa
Prior art keywords
agent
phospholipid
lipospheres
liquid
suspension
Prior art date
Application number
ZA909088A
Other languages
English (en)
Inventor
Abraham J Domb
J Domb Abraham
Manoj Maniar
Maniar Manoj
Original Assignee
Nova Pharm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nova Pharm Corp filed Critical Nova Pharm Corp
Publication of ZA909088B publication Critical patent/ZA909088B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Valve Device For Special Equipments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Lubricants (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA909088A 1989-11-13 1990-11-13 Lipospheres for controlled delivery of substances ZA909088B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43554689A 1989-11-13 1989-11-13

Publications (1)

Publication Number Publication Date
ZA909088B true ZA909088B (en) 1991-07-31

Family

ID=23728827

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA909088A ZA909088B (en) 1989-11-13 1990-11-13 Lipospheres for controlled delivery of substances

Country Status (12)

Country Link
EP (1) EP0502119B1 (xx)
JP (1) JP3233402B2 (xx)
KR (1) KR960005137B1 (xx)
AT (1) ATE133562T1 (xx)
AU (1) AU655162B2 (xx)
CA (1) CA2068216C (xx)
DE (1) DE69025196T2 (xx)
DK (1) DK0502119T3 (xx)
ES (1) ES2085465T3 (xx)
GR (1) GR3019716T3 (xx)
WO (1) WO1991007171A1 (xx)
ZA (1) ZA909088B (xx)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4132677C2 (de) * 1991-10-01 1995-08-24 Braun Melsungen Ag Flüchtige Inhalationsnarkotika enthaltende Liposomen, ihre Herstellung und Verwendung
DE4244466C2 (de) * 1992-12-24 1995-02-23 Pharmatech Gmbh Verfahren zur Herstellung von Pseudolatices und Mikro- oder Nanopartikeln und deren Verwendung zur Herstellung von pharmazeutischen Präparaten
US5885486A (en) * 1993-03-05 1999-03-23 Pharmaciaand Upjohn Ab Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof
CA2091152C (en) * 1993-03-05 2005-05-03 Kirsten Westesen Solid lipid particles, particles of bioactive agents and methods for the manfuacture and use thereof
US5785976A (en) * 1993-03-05 1998-07-28 Pharmacia & Upjohn Ab Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof
US5576016A (en) * 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles
US5961970A (en) * 1993-10-29 1999-10-05 Pharmos Corporation Submicron emulsions as vaccine adjuvants
ATE199316T1 (de) 1993-12-23 2001-03-15 Bruno Gander Mit antigen beladene mikropartikel und pharmazeutische zubereitungen, die diese mikropartikel enthalten.
ATE183092T1 (de) 1995-10-28 1999-08-15 Braun Melsungen Ag Lokalanästhetika und/oder zentralanalgetika enthaltende pharmazeutische zusammensetzungen
NZ503086A (en) * 1997-08-29 2002-03-01 Upjohn Co An orally administrable pharmaceutical composition comprising an inner core and two outer layers, which render it substantially free of unpleasant tastes
AU9496798A (en) 1997-09-19 1999-04-05 Shire Laboratories, Inc. Solid solution beadlet
ES2325141T3 (es) * 1998-07-17 2009-08-26 Pacira Pharmaceuticals, Inc. Composiciones biodegradables para la liberacion controlada de sustancias encapsuladas.
US8052982B2 (en) 1998-07-20 2011-11-08 Peptech Animal Health Pty Limited Bioimplant formulation comprising lecithin and stearin
CA2336879C (en) * 1998-07-20 2010-06-01 Peptech Limited Sustained-release formulations comprising peptides, polypeptides, proteins or nucleic acids as active ingredients
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
FR2805761B1 (fr) * 2000-03-02 2002-08-30 Mainelab Nanocapsules lipidiques, procede de preparation et utilisation comme medicament
ATE329655T1 (de) * 2001-09-06 2006-07-15 Wolfgang Dr Friedrich Verwendung eines gemisches von lidocain und prilocain, sowie mittel zur tumeszenz- lokalanästhesie
US6696490B2 (en) 2002-07-10 2004-02-24 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Slow release insect repellent compounds and process for delivering active
EP1562557B2 (en) 2002-11-01 2016-11-16 University of Medicine and Dentistry of New Jersey Geodate delivery vehicles
JP4601311B2 (ja) * 2004-03-12 2010-12-22 ネイチャーテクノロジー株式会社 球状粒子及びその製造方法
JP4533185B2 (ja) * 2005-02-24 2010-09-01 花王株式会社 固体脂質粒子製剤
US8101274B2 (en) 2007-06-11 2012-01-24 Spedden Richard H Solid state membranes with surface-embedded glycosylated amphiphilic molecules and micelles formed therefrom
PL2299953T3 (pl) 2008-07-14 2017-10-31 Polypid Ltd Kompozycja nośnika leku o przedłużonym uwalnianiu
CN102176882A (zh) 2008-08-07 2011-09-07 生物活性外科公司 医疗器械和植入物的干细胞捕获和固定涂层
CN102470105B (zh) 2009-07-14 2015-07-29 波利皮得有限公司 持续释放药物载体组合物
EP2525778B1 (en) 2010-01-19 2018-08-01 Polypid Ltd. Sustained-release nucleic acid matrix compositions
ES2397992T3 (es) 2010-09-15 2013-03-12 Selkis Sas Derivados de p-mentano-3,8-diol y repelentes contra insectos que los contienen
WO2013171196A1 (en) * 2012-05-15 2013-11-21 Dsm Ip Assets B.V. Antifungal compositions
WO2013178749A1 (fr) 2012-06-01 2013-12-05 Galderma Research & Development Nanocapsules lipidiques comprenant un rétinoide, nanodispersion et composition les contenant, leur procédé de préparation et leur utilisation en dermatologie
EP2823811A1 (en) * 2013-07-09 2015-01-14 OTC GmbH Targeted active release system comprising solid lipid nano-particles
DE102013224627A1 (de) 2013-11-29 2015-06-03 Andreas Lauterbach Pharmazeutische Formulierung mit Lipidmikropartikeln und Herstellungsverfahren
CN105934239A (zh) * 2013-12-04 2016-09-07 盖尔德马研究及发展公司 优选包含亲脂性活性剂的脂质微胶囊和包含它的组合物，它们的制备方法和它们在皮肤病学和化妆品中的用途
WO2016193588A1 (fr) 2015-05-29 2016-12-08 Galderma Research & Development Compositions comprenant au moins un principe actif disperse et des microcapsules lipidiques
US11203793B2 (en) 2015-06-17 2021-12-21 Usui Co., Ltd. Steel pipe for fuel injection pipe and method for producing the same
CN107608422A (zh) * 2017-09-29 2018-01-19 智车优行科技（北京）有限公司 车载温度控制装置
IT201900011436A1 (it) 2019-07-10 2021-01-10 Univ Degli Studi Di Palermo Particelle micrometriche, loro metodo di preparazione e loro usi
KR20220140783A (ko) 2020-02-13 2022-10-18 글리코사이언스 에스엘 휘발성 알코올의 느린 방출을 위한 3'-케토글리코시드 화합물
WO2023057235A1 (en) 2021-10-06 2023-04-13 Glycoscience, S.L. Process for preparing 3'-ketoglycoside compounds
CN118434282A (zh) 2021-11-30 2024-08-02 格莱克科学有限公司 缓释制剂

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4945224B1 (xx) * 1970-12-14 1974-12-03
AR220263A1 (es) * 1980-02-19 1980-10-15 Bago Lab Sa Procedimiento para obtener una preparacion inyectable de sulfonamida potenciada de baja irritabilidad
US4331654A (en) * 1980-06-13 1982-05-25 Eli Lilly And Company Magnetically-localizable, biodegradable lipid microspheres
US4622219A (en) * 1983-06-17 1986-11-11 Haynes Duncan H Method of inducing local anesthesia using microdroplets of a general anesthetic
US4963367A (en) * 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
DE3421468A1 (de) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung
US4797288A (en) * 1984-10-05 1989-01-10 Warner-Lambert Company Novel drug delivery system
AU6021386A (en) * 1985-07-22 1987-01-29 Desoto Inc. Cosmetic comprising sustained release of perfume or pest repellant or the like
CA1338736C (fr) * 1986-12-05 1996-11-26 Roger Baurain Microcristaux comportant une substance active presentant une affinite pour les phospholipides, et au moins un phospholipide, procede de preparation

Also Published As

Publication number Publication date
KR960005137B1 (ko) 1996-04-22
CA2068216C (en) 1999-04-13
EP0502119B1 (en) 1996-01-31
AU6950091A (en) 1991-06-13
CA2068216A1 (en) 1991-05-14
AU655162B2 (en) 1994-12-08
DE69025196D1 (de) 1996-03-14
EP0502119A1 (en) 1992-09-09
GR3019716T3 (en) 1996-07-31
WO1991007171A1 (en) 1991-05-30
JPH05505338A (ja) 1993-08-12
KR920703017A (ko) 1992-12-17
ATE133562T1 (de) 1996-02-15
JP3233402B2 (ja) 2001-11-26
ES2085465T3 (es) 1996-06-01
DK0502119T3 (da) 1996-06-03
DE69025196T2 (de) 1996-11-14

Similar Documents

Publication Publication Date Title
GR3019716T3 (en) Lipospheres for controlled delivery of substances
US4353962A (en) In-flight encapsulation of particles
AU714725B2 (en) Crop protection composition comprising a crop protection solid particle coated with a water-insoluble coating material and a crop protection mixture comprising the same
US4931362A (en) Microcapsule and micromatrix bodies and method for their formation
AU630102B2 (en) Improved flowable insecticidal delivery compositions and methods for controlling insect populations in an aquatic environment
EP0768818B1 (en) Solid microspheres for agriculturally active compounds and process for their production
RU2560943C2 (ru) Микрокапсулированные масла для контроля сноса пестицида при разбрызгивании
US3959464A (en) Microencapsulated methyl and ethyl parathion insecticide in aqueous carrier
CS249110B2 (en) Method of water non-miscible substance encapsulation
EP0141584A2 (en) Durable controlled release microcapsules
ES2208962T3 (es) Nuevo procedimiento de microencapsulacion de agua en aceite y microcapsulas producidas mediante el mismo.
US4871766A (en) Oil-in-water pesticidal emulsion
EP2260075B1 (en) Surfactant compositions
US5039524A (en) Vermin-repellent microcapsules with slow-release potentiality
EP0379379B1 (en) Particulate materials, their production and use
JP2004503513A (ja) マイクロカプセル懸濁液およびその方法
JPS601101A (ja) 水性懸濁農薬製剤
Ohkouchi et al. Basic technology and recent trends in agricultural formulation and application technology
US3479176A (en) Method and multiphase composition for controlling pests
JPS6312441B2 (xx)
JPH1059812A (ja) 殺虫性マイクロカプセル剤組成物
Rathburn Insecticide formulations–types and uses: a review
JP2969916B2 (ja) 改良された有害生物防除剤
JP2867041B2 (ja) 起泡剤
JPH09309801A (ja) 徐放性大粒子水性懸濁農薬製剤