GR3019716T3 - Lipospheres for controlled delivery of substances - Google Patents

Lipospheres for controlled delivery of substances

Info

Publication number
GR3019716T3
GR3019716T3 GR960401101T GR960401101T GR3019716T3 GR 3019716 T3 GR3019716 T3 GR 3019716T3 GR 960401101 T GR960401101 T GR 960401101T GR 960401101 T GR960401101 T GR 960401101T GR 3019716 T3 GR3019716 T3 GR 3019716T3
Authority
GR
Greece
Prior art keywords
agent
phospholipid
lipospheres
liquid
suspension
Prior art date
Application number
GR960401101T
Other languages
English (en)
Inventor
Abraham J Domb
Manoj Maniar
Original Assignee
Scios Nova Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scios Nova Inc filed Critical Scios Nova Inc
Publication of GR3019716T3 publication Critical patent/GR3019716T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Dentistry (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Pest Control & Pesticides (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Preparation (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Valve Device For Special Equipments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Lubricants (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
GR960401101T 1989-11-13 1996-04-23 Lipospheres for controlled delivery of substances GR3019716T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43554689A 1989-11-13 1989-11-13
PCT/US1990/006519 WO1991007171A1 (en) 1989-11-13 1990-11-08 Lipospheres for controlled delivery of substances

Publications (1)

Publication Number Publication Date
GR3019716T3 true GR3019716T3 (en) 1996-07-31

Family

ID=23728827

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960401101T GR3019716T3 (en) 1989-11-13 1996-04-23 Lipospheres for controlled delivery of substances

Country Status (12)

Country Link
EP (1) EP0502119B1 (el)
JP (1) JP3233402B2 (el)
KR (1) KR960005137B1 (el)
AT (1) ATE133562T1 (el)
AU (1) AU655162B2 (el)
CA (1) CA2068216C (el)
DE (1) DE69025196T2 (el)
DK (1) DK0502119T3 (el)
ES (1) ES2085465T3 (el)
GR (1) GR3019716T3 (el)
WO (1) WO1991007171A1 (el)
ZA (1) ZA909088B (el)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107608422A (zh) * 2017-09-29 2018-01-19 智车优行科技（北京）有限公司 车载温度控制装置

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DE4132677C2 (de) * 1991-10-01 1995-08-24 Braun Melsungen Ag Flüchtige Inhalationsnarkotika enthaltende Liposomen, ihre Herstellung und Verwendung
DE4244466C2 (de) * 1992-12-24 1995-02-23 Pharmatech Gmbh Verfahren zur Herstellung von Pseudolatices und Mikro- oder Nanopartikeln und deren Verwendung zur Herstellung von pharmazeutischen Präparaten
US5885486A (en) * 1993-03-05 1999-03-23 Pharmaciaand Upjohn Ab Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof
US5785976A (en) * 1993-03-05 1998-07-28 Pharmacia & Upjohn Ab Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof
CA2091152C (en) * 1993-03-05 2005-05-03 Kirsten Westesen Solid lipid particles, particles of bioactive agents and methods for the manfuacture and use thereof
US5576016A (en) * 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles
US5961970A (en) * 1993-10-29 1999-10-05 Pharmos Corporation Submicron emulsions as vaccine adjuvants
US6596278B2 (en) 1993-12-23 2003-07-22 Rmf Dictagene S.A. Immunological response potentiation process
ES2138130T3 (es) 1995-10-28 2000-01-01 Braun Melsungen Ag Composicion farmaceutica que contiene un anestesico local y/o un analgesico de accion central.
NZ503086A (en) * 1997-08-29 2002-03-01 Upjohn Co An orally administrable pharmaceutical composition comprising an inner core and two outer layers, which render it substantially free of unpleasant tastes
WO1999013864A2 (en) * 1997-09-19 1999-03-25 Shire Laboratories, Inc. Solid solution beadlet
DE69940735D1 (de) * 1998-07-17 2009-05-28 Pacira Pharmaceuticals Inc Biologisch abbaubare anordnungen zur kontrollierten freigabe eingeschlossener substanzen
US8052982B2 (en) 1998-07-20 2011-11-08 Peptech Animal Health Pty Limited Bioimplant formulation comprising lecithin and stearin
BR9912275A (pt) * 1998-07-20 2001-04-17 Peptech Ltd Formulação de bioimplante
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
FR2805761B1 (fr) * 2000-03-02 2002-08-30 Mainelab Nanocapsules lipidiques, procede de preparation et utilisation comme medicament
ATE329655T1 (de) * 2001-09-06 2006-07-15 Wolfgang Dr Friedrich Verwendung eines gemisches von lidocain und prilocain, sowie mittel zur tumeszenz- lokalanästhesie
US6696490B2 (en) 2002-07-10 2004-02-24 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Slow release insect repellent compounds and process for delivering active
WO2004041247A2 (en) 2002-11-01 2004-05-21 Biodelivery Sciences International, Inc. Geodate delivery vehicles
JP4601311B2 (ja) * 2004-03-12 2010-12-22 ネイチャーテクノロジー株式会社 球状粒子及びその製造方法
JP4533185B2 (ja) * 2005-02-24 2010-09-01 花王株式会社 固体脂質粒子製剤
US8101274B2 (en) 2007-06-11 2012-01-24 Spedden Richard H Solid state membranes with surface-embedded glycosylated amphiphilic molecules and micelles formed therefrom
CA2730340C (en) 2008-07-14 2017-02-07 Polypid Ltd. Sustained-release drug carrier composition
CN102176882A (zh) 2008-08-07 2011-09-07 生物活性外科公司 医疗器械和植入物的干细胞捕获和固定涂层
US8992979B2 (en) 2009-07-14 2015-03-31 Polypid Ltd. Sustained-release drug carrier composition
US8795726B2 (en) 2010-01-19 2014-08-05 Polypid Ltd. Sustained-release nucleic acid matrix compositions
PT2439188E (pt) 2010-09-15 2012-11-14 Selkis Sas Derivados de p-mentano-3,8-diol e meios de proteção contra insetos que os contêm
WO2013171196A1 (en) * 2012-05-15 2013-11-21 Dsm Ip Assets B.V. Antifungal compositions
WO2013178749A1 (fr) 2012-06-01 2013-12-05 Galderma Research & Development Nanocapsules lipidiques comprenant un rétinoide, nanodispersion et composition les contenant, leur procédé de préparation et leur utilisation en dermatologie
EP2823811A1 (en) * 2013-07-09 2015-01-14 OTC GmbH Targeted active release system comprising solid lipid nano-particles
DE102013224627A1 (de) 2013-11-29 2015-06-03 Andreas Lauterbach Pharmazeutische Formulierung mit Lipidmikropartikeln und Herstellungsverfahren
JP2016539161A (ja) * 2013-12-04 2016-12-15 ガルデルマ・リサーチ・アンド・デヴェロップメント 好ましくは親油性活性物質を含む脂質マイクロカプセル、並びにそれを含有する組成物、それらの製造のための方法、並びに皮膚科学及び化粧品におけるそれらの使用
WO2016193588A1 (fr) 2015-05-29 2016-12-08 Galderma Research & Development Compositions comprenant au moins un principe actif disperse et des microcapsules lipidiques
WO2016203924A1 (ja) 2015-06-17 2016-12-22 臼井国際産業株式会社 燃料噴射管用鋼管およびその製造方法
IT201900011436A1 (it) 2019-07-10 2021-01-10 Univ Degli Studi Di Palermo Particelle micrometriche, loro metodo di preparazione e loro usi
EP4103576A1 (en) 2020-02-13 2022-12-21 Glycoscience, S.L. 3'-ketoglycoside compound for the slow release of a volatile alcohol
WO2023057235A1 (en) 2021-10-06 2023-04-13 Glycoscience, S.L. Process for preparing 3'-ketoglycoside compounds
WO2023099327A1 (en) 2021-11-30 2023-06-08 Glycoscience, S.L. Slow-release formulation

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JPS4945224B1 (el) * 1970-12-14 1974-12-03
AR220263A1 (es) * 1980-02-19 1980-10-15 Bago Lab Sa Procedimiento para obtener una preparacion inyectable de sulfonamida potenciada de baja irritabilidad
US4331654A (en) * 1980-06-13 1982-05-25 Eli Lilly And Company Magnetically-localizable, biodegradable lipid microspheres
US4622219A (en) * 1983-06-17 1986-11-11 Haynes Duncan H Method of inducing local anesthesia using microdroplets of a general anesthetic
US4963367A (en) * 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
DE3421468A1 (de) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung
US4797288A (en) * 1984-10-05 1989-01-10 Warner-Lambert Company Novel drug delivery system
AU6021386A (en) * 1985-07-22 1987-01-29 Desoto Inc. Cosmetic comprising sustained release of perfume or pest repellant or the like
CA1338736C (fr) * 1986-12-05 1996-11-26 Roger Baurain Microcristaux comportant une substance active presentant une affinite pour les phospholipides, et au moins un phospholipide, procede de preparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107608422A (zh) * 2017-09-29 2018-01-19 智车优行科技（北京）有限公司 车载温度控制装置

Also Published As

Publication number Publication date
EP0502119A1 (en) 1992-09-09
AU6950091A (en) 1991-06-13
JP3233402B2 (ja) 2001-11-26
DE69025196T2 (de) 1996-11-14
DE69025196D1 (de) 1996-03-14
WO1991007171A1 (en) 1991-05-30
KR920703017A (ko) 1992-12-17
JPH05505338A (ja) 1993-08-12
EP0502119B1 (en) 1996-01-31
ES2085465T3 (es) 1996-06-01
DK0502119T3 (da) 1996-06-03
ATE133562T1 (de) 1996-02-15
KR960005137B1 (ko) 1996-04-22
CA2068216C (en) 1999-04-13
CA2068216A1 (en) 1991-05-14
AU655162B2 (en) 1994-12-08
ZA909088B (en) 1991-07-31

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