ZA906927B - Neurotrophin-3,a neutrotrophic factor related to nerve growth and brain derived neurotrophic factor - Google Patents
Neurotrophin-3,a neutrotrophic factor related to nerve growth and brain derived neurotrophic factorInfo
- Publication number
- ZA906927B ZA906927B ZA906927A ZA906927A ZA906927B ZA 906927 B ZA906927 B ZA 906927B ZA 906927 A ZA906927 A ZA 906927A ZA 906927 A ZA906927 A ZA 906927A ZA 906927 B ZA906927 B ZA 906927B
- Authority
- ZA
- South Africa
- Prior art keywords
- neurotrophin
- factor
- nerve growth
- derived neurotrophic
- brain derived
- Prior art date
Links
- 102000004219 Brain-derived neurotrophic factor Human genes 0.000 title 1
- 108090000715 Brain-derived neurotrophic factor Proteins 0.000 title 1
- 108010025020 Nerve Growth Factor Proteins 0.000 title 1
- 102000015336 Nerve Growth Factor Human genes 0.000 title 1
- 108090000742 Neurotrophin 3 Proteins 0.000 title 1
- 102100029268 Neurotrophin-3 Human genes 0.000 title 1
- 229940077737 brain-derived neurotrophic factor Drugs 0.000 title 1
- 229940053128 nerve growth factor Drugs 0.000 title 1
- 229940032018 neurotrophin 3 Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/48—Nerve growth factor [NGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
- F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
- F02B75/00—Other engines
- F02B75/02—Engines characterised by their cycles, e.g. six-stroke
- F02B2075/022—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
- F02B2075/027—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/400,591 US5180820A (en) | 1989-08-30 | 1989-08-30 | Brain-derived neurotrophic factor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA906927B true ZA906927B (en) | 1991-06-26 |
Family
ID=23584217
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA906927A ZA906927B (en) | 1989-08-30 | 1990-08-30 | Neurotrophin-3,a neutrotrophic factor related to nerve growth and brain derived neurotrophic factor |
| ZA906926A ZA906926B (en) | 1989-08-30 | 1990-08-30 | Brain derived neurotrophic factor |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA906926A ZA906926B (en) | 1989-08-30 | 1990-08-30 | Brain derived neurotrophic factor |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5180820A (cs) |
| JP (1) | JP2783450B2 (cs) |
| CZ (1) | CZ285649B6 (cs) |
| DD (2) | DD299197A5 (cs) |
| GR (1) | GR1002052B (cs) |
| LT (2) | LT4011B (cs) |
| RU (2) | RU2131926C1 (cs) |
| ZA (2) | ZA906927B (cs) |
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6709837B1 (en) * | 1989-03-10 | 2004-03-23 | Takeda Chemical Industries, Inc. | Polypeptide and production thereof |
| US6780837B1 (en) * | 1989-08-30 | 2004-08-24 | The Regents Of The University Of California | Prevention of retinal injury and degeneration by specific factors |
| US6933276B1 (en) | 1989-08-30 | 2005-08-23 | Regeneron Pharmaceuticals, Inc. | Methods of treating peripheral neuropathies using neurotrophin-3 |
| US6174701B1 (en) * | 1989-12-12 | 2001-01-16 | Genentech, Inc. | Neuronal factor |
| US5235043A (en) * | 1990-04-06 | 1993-08-10 | Synergen, Inc. | Production of biologically active, recombinant members of the ngf/bdnf family of neurotrophic proteins |
| US5986070A (en) * | 1990-04-06 | 1999-11-16 | Amgen Inc. | Production of biologically active NGF proteins |
| US5606031A (en) * | 1990-04-06 | 1997-02-25 | Lile; Jack | Production and purification of biologically active recombinant neurotrophic protein in bacteria |
| US5169764A (en) * | 1990-08-08 | 1992-12-08 | Regeneron Pharmaceuticals, Inc. | Multitrophic and multifunctional chimeric neurotrophic factors, and nucleic acids and plasmids encoding the chimeras |
| FR2671487B1 (fr) * | 1991-01-14 | 1993-03-19 | Oreal | Utilisation d'un facteur de croissance dans une composition amincissante. |
| US5792900A (en) * | 1991-10-21 | 1998-08-11 | The Trustees Of The University Of Pennsylvania | Compositions and methods for producing and using homogenous neuronal cell transplants |
| US5175103A (en) * | 1991-10-21 | 1992-12-29 | Trustees Of University Of Pennsylvania | Preparation of pure cultures of post-mitotic human neurons |
| ATE163006T1 (de) * | 1993-06-01 | 1998-02-15 | Ono Pharmaceutical Co | Pentansäurederivate |
| US5602309A (en) * | 1993-10-04 | 1997-02-11 | University Of Kentucky Research Foundation | Transgenic mice which overexpress nerve growth factor |
| CA2176216A1 (en) * | 1993-11-09 | 1995-05-18 | Virginia M.-Y. Lee | Compositions and methods for producing and using homogeneous neuronal cell transplants |
| US5556837A (en) * | 1994-08-01 | 1996-09-17 | Regeneron Pharmaceuticals Inc. | Methods for treating addictive disorders |
| ATE232089T1 (de) * | 1994-11-10 | 2003-02-15 | Univ Kentucky Res Found | Implantierbare wiederauffüllbare vorrichtung mit gesteuerter freisetzung zur verabreichung von arzneistoffen unmittelbar an einen inneren teil des körpers |
| US5770577A (en) * | 1994-11-14 | 1998-06-23 | Amgen Inc. | BDNF and NT-3 polypeptides selectively linked to polyethylene glycol |
| US5830857A (en) * | 1995-07-14 | 1998-11-03 | Amgen Inc. | Method of treating epilepsy |
| US5859311A (en) * | 1995-11-27 | 1999-01-12 | University Of Kentucky Research Foundation | Transgenic mice which overexpress neurotrophin-3 (NT-3) and methods of use |
| US6299895B1 (en) | 1997-03-24 | 2001-10-09 | Neurotech S.A. | Device and method for treating ophthalmic diseases |
| JPH10212241A (ja) * | 1996-05-27 | 1998-08-11 | Sumitomo Pharmaceut Co Ltd | Bdnfを安定に含有する製剤 |
| TR199901734T2 (xx) * | 1996-11-15 | 2000-01-21 | Genentech, Inc. | N�rotrofinlerin ar�t�lmas�. |
| AU718500B2 (en) | 1997-01-23 | 2000-04-13 | Sumitomo Pharmaceuticals Company, Limited | Remedies for diabetes |
| US6331523B1 (en) | 1998-03-12 | 2001-12-18 | Genentech, Inc. | Method of enhancing the survival of retinal neurons and treating ocular diseases using FGF-5 |
| US6391544B1 (en) * | 1998-05-15 | 2002-05-21 | Abbott Laboratories | Method for using unequal primer concentrations for generating nucleic acid amplification products |
| IL141755A0 (en) * | 1998-09-04 | 2002-03-10 | Wolfe Res Pty Ltd | Medical implant system |
| ATE406907T1 (de) * | 1998-10-28 | 2008-09-15 | Cornell Res Foundation Inc | Methoden zur regulierung der angiogenese und vaskuläre integrität mittels trk rezeptor liganden bdnf, nt-3 und nt-4 |
| JP2000169389A (ja) * | 1998-12-08 | 2000-06-20 | Sumitomo Pharmaceut Co Ltd | 触覚異常治療剤 |
| RU2156621C1 (ru) * | 1999-03-04 | 2000-09-27 | Эпштейн Олег Ильич | Нейротропное лекарственное средство |
| US7037493B2 (en) | 2000-05-01 | 2006-05-02 | Cornell Research Foundation, Inc. | Method of inducing neuronal production in the brain and spinal cord |
| US6852323B2 (en) | 2000-07-21 | 2005-02-08 | The Regents Of The University Of California | Methods and compositions for preventing and treating male erectile dysfunction and female sexual arousal disorder |
| US7223406B2 (en) | 2000-07-21 | 2007-05-29 | The Regents Of The University Of California | Methods and compositions for preventing and treating male erectile dysfunction and female sexual arousal disorder |
| JP2002223748A (ja) * | 2001-01-31 | 2002-08-13 | Norio Sakuragawa | 網膜神経節細胞培養用培地、眼科用組成物及び網膜神経節細胞保護剤 |
| EP1373905A2 (de) * | 2001-04-06 | 2004-01-02 | BioVisioN AG | Verfahren zum nachweis chronisch-demenzieller erkrankungen, zugehörige peptide und nachweisreagenzien |
| WO2003070189A2 (en) * | 2002-02-15 | 2003-08-28 | Cornell Research Foundation, Inc. | Enhancing neurotrophin-induced neurogenesis by endogenous neural progenitor cells by concurrent overexpression of brain derived neurotrophic factor and an inhibitor of a pro-gliogenic bone morphogenetic protein |
| US20030219696A1 (en) * | 2002-05-23 | 2003-11-27 | Moreland Gerald W. | Method and apparatus for preventing backflow in dental saliva evacuators |
| GB0228832D0 (en) | 2002-12-10 | 2003-01-15 | Novartis Ag | Organic compound |
| US7388079B2 (en) * | 2002-11-27 | 2008-06-17 | The Regents Of The University Of California | Delivery of pharmaceutical agents via the human insulin receptor |
| US20050048041A1 (en) * | 2003-01-13 | 2005-03-03 | Rao Mahendra S. | Persistent expression of candidate molecule in proliferating stem and progenitor cells for delivery of therapeutic products |
| SI2248899T1 (sl) | 2003-03-19 | 2015-07-31 | Biogen Ma Inc. | Vezavni protein receptorja Nogo |
| RU2265446C2 (ru) * | 2003-05-14 | 2005-12-10 | Григорьянц Рубен Исаакович | Имплантат для лечения болезни паркинсона |
| EP1500399A1 (en) * | 2003-07-24 | 2005-01-26 | Institut Pasteur | Active or passive immunization against proapoptotic neurotrophins for the treatment or prevention of neurodegenerative deseases |
| US20060094064A1 (en) * | 2003-11-19 | 2006-05-04 | Sandip Ray | Methods and compositions for diagnosis, stratification, and monitoring of alzheimer's disease and other neurological disorders in body fluids |
| ES2411455T3 (es) * | 2003-11-19 | 2013-07-05 | Rules-Based Medicine, Inc. | Procedimiento para el diagnóstico y la monitorización de la enfermedad de Alzheimer |
| JP2007537145A (ja) * | 2003-12-22 | 2007-12-20 | グラクソ グループ リミテッド | アルツハイマー病の治療のためのnogoa抗体 |
| KR101637908B1 (ko) | 2004-04-07 | 2016-07-11 | 리나트 뉴로사이언스 코프. | 신경성장인자 길항제의 투여에 의한 골암 통증의 치료방법 |
| US7037698B2 (en) | 2004-05-19 | 2006-05-02 | Amano Enzyme Inc. | Pyrroloquinoline quinone-dependent glucose dehydrogenase |
| JP4960865B2 (ja) | 2004-06-24 | 2012-06-27 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 脱髄に関連する状態の処置 |
| CA2614421A1 (en) | 2005-07-08 | 2007-01-18 | Biogen Idec Ma Inc. | Sp35 antibodies and uses thereof |
| US8741260B2 (en) * | 2005-10-07 | 2014-06-03 | Armagen Technologies, Inc. | Fusion proteins for delivery of GDNF to the CNS |
| US8053569B2 (en) * | 2005-10-07 | 2011-11-08 | Armagen Technologies, Inc. | Nucleic acids encoding and methods of producing fusion proteins |
| US8124095B2 (en) * | 2005-10-07 | 2012-02-28 | Armagen Technologies, Inc. | Fusion proteins for delivery of erythropoietin to the CNS |
| US8497246B2 (en) * | 2006-08-18 | 2013-07-30 | Armagen Technologies, Inc. | Methods for diagnosing and treating CNS disorders by trans-blood-brain barrier delivery of protein compositions |
| AU2007320311B2 (en) | 2006-11-17 | 2012-03-15 | The Research Foundation For Microbial Diseases Of Osaka University | Nerve elongation promoter and elongation inhibitor |
| US20090011040A1 (en) * | 2007-05-02 | 2009-01-08 | Naash Muna I | Use of compacted nucleic acid nanoparticles in non-viral treatments of ocular diseases |
| US8974791B2 (en) | 2007-07-27 | 2015-03-10 | Armagen Technologies, Inc. | Methods and compositions for increasing α-L-iduronidase activity in the CNS |
| WO2009061500A1 (en) * | 2007-11-08 | 2009-05-14 | Biogen Idec Ma Inc. | Use of lingo-4 antagonists in the treatment of conditions involving demyelination |
| US8058406B2 (en) | 2008-07-09 | 2011-11-15 | Biogen Idec Ma Inc. | Composition comprising antibodies to LINGO or fragments thereof |
| US20100112557A1 (en) * | 2008-11-03 | 2010-05-06 | Applied Biosystems Inc. | Method for high resolution melt genotyping |
| US20100112565A1 (en) * | 2008-11-03 | 2010-05-06 | Life Technologies Corporation | Methods, kits, and reaction mixtures for high resolution melt genotyping |
| WO2010079850A2 (en) | 2009-01-12 | 2010-07-15 | Takeda Pharmaceutical Company Limited | Agent for prophylaxis or treatment of cancer |
| PT2396038E (pt) | 2009-02-12 | 2016-02-19 | Curna Inc | Tratamento das doenças associadas com o factor neurotrófico derivado do cérebro (bdnf) por inibição do produto antisenso natural da transcrição para bdnf |
| JP5873003B2 (ja) | 2009-03-18 | 2016-03-01 | アーメイゲン・テクノロジーズ・インコーポレイテッドArmagen Technologies, Inc. | IgGデコイ受容体融合タンパク質の血液脳関門送達のための組成物および方法 |
| EP4273164A3 (en) | 2009-10-09 | 2024-01-24 | Armagen, Inc. | Methods and compositions for increasing iduronate 2-sulfatase activity in the cns |
| RU2606012C2 (ru) * | 2009-11-09 | 2017-01-10 | Дженепод Терапевтикс Аб | Новая вирусная векторная конструкция для нейронспецифического оптимизированного непрерывного синтеза dopa in vivo |
| US9884909B2 (en) | 2010-12-01 | 2018-02-06 | Alderbio Holdings Llc | Anti-NGF compositions and use thereof |
| EP2646468B1 (en) | 2010-12-01 | 2018-07-25 | AlderBio Holdings LLC | Anti-ngf compositions and use thereof |
| US9067988B2 (en) | 2010-12-01 | 2015-06-30 | Alderbio Holdings Llc | Methods of preventing or treating pain using anti-NGF antibodies |
| US9539324B2 (en) | 2010-12-01 | 2017-01-10 | Alderbio Holdings, Llc | Methods of preventing inflammation and treating pain using anti-NGF compositions |
| US9078878B2 (en) | 2010-12-01 | 2015-07-14 | Alderbio Holdings Llc | Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75 |
| US11214610B2 (en) | 2010-12-01 | 2022-01-04 | H. Lundbeck A/S | High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris |
| US9149427B2 (en) | 2010-12-02 | 2015-10-06 | Neurotech Usa, Inc. | Cell lines that secrete anti-angiogenic antibody-scaffolds and soluble receptors and uses thereof |
| ES2983576T3 (es) | 2011-12-02 | 2024-10-23 | Armagen Inc | Métodos y composiciones para aumentar la actividad arilsulfatasa en el SNC |
| ES2694592T3 (es) * | 2012-03-15 | 2018-12-21 | Curna, Inc. | Tratamiento de enfermedades relacionadas con el factor neurotrófico derivado del cerebro (BDNF) por inhibición del transcrito antisentido natural de BDNF |
| WO2013173364A2 (en) | 2012-05-14 | 2013-11-21 | Biogen Idec Ma Inc. | Lingo-2 antagonists for treatment of conditions involving motor neurons |
| AU2016205197B2 (en) | 2015-01-08 | 2021-10-21 | Biogen Ma Inc. | LINGO-1 antagonists and uses for treatment of demyelinating disorders |
| US10538589B2 (en) | 2015-01-14 | 2020-01-21 | Armagen Inc. | Methods and compositions for increasing N-acetylglucosaminidase (NAGLU) activity in the CNS using a fusion antibody comprising an anti-human insulin receptor antibody and NAGLU |
| JP6850734B2 (ja) | 2015-05-27 | 2021-03-31 | ニューロテック ユーエスエー, インコーポレイテッド | 眼の障害の処置のためのカプセル化細胞療法の使用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3213963A1 (de) * | 1982-04-15 | 1983-10-27 | Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Neurotropher faktor |
| US4620948A (en) * | 1982-12-22 | 1986-11-04 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US4511502A (en) * | 1982-12-22 | 1985-04-16 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| DK161152C (da) * | 1983-03-03 | 1991-11-11 | Genentech Inc | Polypeptid med egenskaber som human beta-nervevaekstfaktor og fremgangsmaade til fremstilling deraf, dna-isolat omfattende en sekvens som koder for polypeptidet, replicerbar udtrykkelsesvektor for dna-sekvensen, rekombinant vaertscelle transformeret med vektoren, farmaceutisk praeparat indeholdende polypeptidet og fremg. der omfatter anvendelsen af polypeptidet til fremst. af et farmaceutisk praeparat |
| US4935370A (en) * | 1983-12-23 | 1990-06-19 | Pfizer Inc. | Expression plasmids for improved production of heterologous protein in bacteria |
| US4758512A (en) * | 1984-03-06 | 1988-07-19 | President And Fellows Of Harvard College | Hosts and methods for producing recombinant products in high yields |
| US4680262A (en) * | 1984-10-05 | 1987-07-14 | Genentech, Inc. | Periplasmic protein recovery |
| US4734362A (en) * | 1986-02-03 | 1988-03-29 | Cambridge Bioscience Corporation | Process for purifying recombinant proteins, and products thereof |
| CA1310602C (en) * | 1986-06-03 | 1992-11-24 | Hajime Horii | Yeast promoter and process for preparing heterologous protein |
| IT1219839B (it) * | 1988-02-08 | 1990-05-24 | Fidia Farmaceutici | Purificazione,caratterizazione e applicazione di un fattore neuronotrofico derivato da cervello di nammifero |
| US4961969A (en) * | 1987-05-11 | 1990-10-09 | Cetus Corporation | Process for recovering microbially produced interferon-β |
| KR890701605A (ko) * | 1987-07-04 | 1989-12-21 | 원본미기재 | Dna 서열, 재조합 dna 분자 및 용해성 t4 단백질의 제조방법 |
| IT1219874B (it) * | 1988-03-18 | 1990-05-24 | Fidia Farmaceutici | Utilizzazione del fattore di crescita nervoso umano e sue composizioni farmaceutiche |
| US5272063A (en) * | 1988-11-22 | 1993-12-21 | Syntex (U.S.A.) Inc. | Process of making human nerve growth factor |
| WO1990006764A1 (en) * | 1988-12-15 | 1990-06-28 | Invitron Corporation | Use of basic amino acids to solubilize immunoglobulins |
| US6709837B1 (en) * | 1989-03-10 | 2004-03-23 | Takeda Chemical Industries, Inc. | Polypeptide and production thereof |
| WO1990014363A1 (en) * | 1989-05-19 | 1990-11-29 | Amgen Inc. | Metalloproteinase inhibitor |
| EP0414151B1 (en) * | 1989-08-21 | 1995-03-15 | Takeda Chemical Industries, Ltd. | Production of human nerve growth factor proteins |
| IL95511A (en) * | 1989-08-30 | 2000-10-31 | Max Planck Gesellschaft | Neurotrophin-3 a novel neurotrophic factor related to nerve growth and brain derived neurotrophic factor |
| US5229500A (en) * | 1989-08-30 | 1993-07-20 | Regeneron Pharmaceuticals, Inc. | Brain derived neurotrophic factor |
| US5235043A (en) * | 1990-04-06 | 1993-08-10 | Synergen, Inc. | Production of biologically active, recombinant members of the ngf/bdnf family of neurotrophic proteins |
| AU654302B2 (en) * | 1990-09-25 | 1994-11-03 | Genentech Inc. | Novel neurothrophic factor |
| US7020718B2 (en) | 2000-05-15 | 2006-03-28 | Hewlett-Packard Development Company, L.P. | System and method of aggregating discontiguous address ranges into addresses and masks using a plurality of repeating address blocks |
-
1989
- 1989-08-30 US US07/400,591 patent/US5180820A/en not_active Expired - Lifetime
-
1990
- 1990-08-29 RU SU4895661A patent/RU2131926C1/ru active
- 1990-08-29 RU SU4895662A patent/RU2128226C1/ru active
- 1990-08-30 ZA ZA906927A patent/ZA906927B/xx unknown
- 1990-08-30 DD DD90343741A patent/DD299197A5/de unknown
- 1990-08-30 CZ CS904229A patent/CZ285649B6/cs not_active IP Right Cessation
- 1990-08-30 ZA ZA906926A patent/ZA906926B/xx unknown
- 1990-08-30 JP JP2229504A patent/JP2783450B2/ja not_active Expired - Lifetime
- 1990-08-30 DD DD90343740A patent/DD299196A5/de unknown
- 1990-08-30 GR GR900100653A patent/GR1002052B/el not_active IP Right Cessation
-
1992
- 1992-01-21 US US07/823,117 patent/US5453361A/en not_active Expired - Lifetime
-
1993
- 1993-12-07 LT LTIP1546A patent/LT4011B/lt not_active IP Right Cessation
-
1994
- 1994-01-28 LT LTIP1818A patent/LT4063B/lt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DD299196A5 (de) | 1992-04-02 |
| GR900100653A (el) | 1991-12-30 |
| LTIP1546A (en) | 1995-07-25 |
| US5453361A (en) | 1995-09-26 |
| RU2131926C1 (ru) | 1999-06-20 |
| LT4063B (en) | 1996-11-25 |
| RU2128226C1 (ru) | 1999-03-27 |
| LT4011B (en) | 1996-08-26 |
| US5180820A (en) | 1993-01-19 |
| DD299197A5 (de) | 1992-04-02 |
| ZA906926B (en) | 1991-06-26 |
| JPH05328974A (ja) | 1993-12-14 |
| LTIP1818A (en) | 1995-09-25 |
| JP2783450B2 (ja) | 1998-08-06 |
| CZ285649B6 (cs) | 1999-10-13 |
| CZ422990A3 (cs) | 1999-06-16 |
| GR1002052B (en) | 1995-11-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ZA906927B (en) | Neurotrophin-3,a neutrotrophic factor related to nerve growth and brain derived neurotrophic factor | |
| GB2231482B (en) | Helmet assemblies | |
| KR960008863B1 (en) | Rom and process for producing the same | |
| EP0263446A3 (en) | Prints and production method thereof | |
| IL92958A (en) | Purified human sciatic nerve ciliary neurotrophic factor and methods for the preparation thereof | |
| GR871294B (en) | Oven product and preparation method therefor | |
| HUT45055A (en) | Process for producing hexahydro-8-hydroxy-2,6-methano-2h-3(4h)-one-esters and their derivatives | |
| EP0410719A3 (en) | Colour correction system and method | |
| GB2159520B (en) | 1, 24-dihydroxy- 22-vitamin d3 and process for preparing same | |
| PL286433A1 (en) | Electrolyzer segment, especially of the filtration press type and a monopolar electrolyzer, especially of the filtration press type | |
| EP0256537A3 (en) | Color print and a method for producing the same | |
| GB8921226D0 (en) | Chiral 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and precursors and preparation thereof | |
| DE3760508D1 (en) | 1,1-dichloro-1,2,2-trimethyl-2-phenyldisilane and method for producing the same | |
| EP0252391A3 (en) | 1,2,2-trimethyl-1-phenyl polydisilane and method for producing the same | |
| GB8629817D0 (en) | Producing filaments | |
| EP0413999A3 (en) | N,n-bis-1,3,5-triazine-6-yl-piperazines and processes for their preparation | |
| DE3661830D1 (en) | 2,4-dichlorothiazole derivatives and process for their preparation | |
| GB2195630B (en) | Method for producing carnitine, l-carnitineamide hydrolase and method for producing same | |
| GB2186570B (en) | 9,10-dihydro-phenanthrene derivatives and process for their preparation | |
| GB2199827B (en) | Novel aminoalkanoyl-dibenzo[d,g][1,3,6]dioxazocines and a process for the preparation thereof | |
| EP0274066A3 (en) | Benzothiazolones, and their production and use | |
| GB2198179B (en) | Rocker assemblies | |
| EP0313740A3 (en) | N-phenyl-2,2,6,6-tetrahalocyclohexaneimine and processes for preparing 2,2,6,6-tetrahalocyclohexaneimine derivative and 2,6-dihaloaniline derivative | |
| EP0258773A3 (en) | Benzothiazolones, and their production and use | |
| GB8710307D0 (en) | Producing crown wheel cam |