ZA886443B - Substituted 2-phenyl-4-quinoline carboxylic acids - Google Patents

Substituted 2-phenyl-4-quinoline carboxylic acids

Info

Publication number
ZA886443B
ZA886443B ZA886443A ZA886443A ZA886443B ZA 886443 B ZA886443 B ZA 886443B ZA 886443 A ZA886443 A ZA 886443A ZA 886443 A ZA886443 A ZA 886443A ZA 886443 B ZA886443 B ZA 886443B
Authority
ZA
South Africa
Prior art keywords
phenyl
substituted
carboxylic acids
quinoline carboxylic
quinoline
Prior art date
Application number
ZA886443A
Other languages
English (en)
Inventor
Leslie H Sutherland
H Sutherland Leslie
Adolph E Sloboda
E Sloboda Adolph
Ralph Grassing Child
Grassing Child Ralph
John F Poletto
F Poletto John
Dennis W Powell
W Powell Dennis
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of ZA886443B publication Critical patent/ZA886443B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
    • C07D215/52—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA886443A 1987-08-31 1988-08-30 Substituted 2-phenyl-4-quinoline carboxylic acids ZA886443B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/090,996 US4847381A (en) 1987-08-31 1987-08-31 2-Phenyl-4-quinoline carboxylic acids

Publications (1)

Publication Number Publication Date
ZA886443B true ZA886443B (en) 1989-04-26

Family

ID=22225261

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA886443A ZA886443B (en) 1987-08-31 1988-08-30 Substituted 2-phenyl-4-quinoline carboxylic acids

Country Status (24)

Country Link
US (1) US4847381A (fi)
EP (1) EP0305952B1 (fi)
JP (1) JP2760379B2 (fi)
KR (1) KR970005909B1 (fi)
AR (1) AR245698A1 (fi)
AT (1) ATE90079T1 (fi)
AU (1) AU613661B2 (fi)
CA (1) CA1333606C (fi)
CS (1) CS274434B2 (fi)
DD (1) DD282225A5 (fi)
DE (1) DE3881456T2 (fi)
DK (1) DK169473B1 (fi)
ES (1) ES2058191T3 (fi)
FI (1) FI92692C (fi)
GR (1) GR3008033T3 (fi)
HU (1) HU202498B (fi)
IE (1) IE65148B1 (fi)
IL (1) IL87457A (fi)
NO (1) NO174961C (fi)
NZ (1) NZ225924A (fi)
PH (1) PH26258A (fi)
PL (1) PL156232B1 (fi)
PT (1) PT88365B (fi)
ZA (1) ZA886443B (fi)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4968701A (en) * 1988-04-26 1990-11-06 E. I. Du Pont De Nemours And Company 4-Quinoline carboxylic acid derivatives useful as immunosuppressive agents
US4918077A (en) * 1989-01-25 1990-04-17 E. I. Du Pont De Nemours & Co., Inc. 3-phenyl-5,6-dihydrobenz(c)acridine-7-carboxylic acids and related compounds as cancer chemotherapeutic agents
US5204329A (en) * 1990-06-11 1993-04-20 Du Pont Merck Pharmaceutical Company Treatment of organ transplantation rejection
US5135934A (en) * 1990-07-06 1992-08-04 Du Pont Merck Pharmaceutical Company 3-phenyl-5,6-dihydrobenz(c) acridine-7-carboxylic acids and related compounds as immunosuppressive agents
US5409886A (en) * 1993-02-18 1995-04-25 Mitsui Toatsu Chemicals, Incorporated 3-pyrroline-2-one derivatives and herbicidal compositions containing same
US5428040A (en) * 1993-08-31 1995-06-27 The Du Pont Merck Pharmaceutical Company Carbocyclic fused-ring quinolinecarboxylic acids useful as immunosuppressive agents
US5578609A (en) * 1994-03-25 1996-11-26 The Dupont Merck Pharmaceutical Company 2-carbocyclic and 2-heterocyclic quinoline-4-carboxylic acids and salts thereof useful as immunosuppressive agents
ID18663A (id) 1996-04-12 1998-04-30 Novartis Ag Komposisi farmasi berlapis enterik
KR20010014030A (ko) 1997-06-19 2001-02-26 더글라스이.리디치 퀴놀린-인돌 항균제, 이들의 용도 및 조성물
US6103905A (en) * 1997-06-19 2000-08-15 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
US6376670B1 (en) 1997-06-19 2002-04-23 Sepracor Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
US6207679B1 (en) 1997-06-19 2001-03-27 Sepracor, Inc. Antimicrobial agents uses and compositions related thereto
WO1999038846A1 (en) * 1998-01-30 1999-08-05 Procept, Inc. Immunosuppressive agents
SE9901366D0 (sv) * 1999-04-16 1999-04-16 Pharmacia & Upjohn Ab Injector device and method for its operation
US20020121638A1 (en) * 2000-06-30 2002-09-05 Vladimir Grushin Electroluminescent iridium compounds with fluorinated phenylpyridines, phenylpyrimidines, and phenylquinolines and devices made with such compounds
WO2009016812A1 (ja) * 2007-07-27 2009-02-05 Kowa Company, Ltd. ２－フェニルキノリン－４－カルボン酸誘導体を有効成分とする貧血の予防及び／又は治療剤
AU2014352920A1 (en) 2013-11-22 2016-06-23 Genzyme Corporation Novel methods for treating neurodegenerative diseases

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2776290A (en) * 1957-01-01 Hydroxy cevchoninates and carboxylic
US2008923A (en) * 1931-07-09 1935-07-23 Graham Patmore L Cinchoninic acid salts of piperazines
US2077903A (en) * 1933-12-15 1937-04-20 Gen Aniline Works Inc Process of preparing 3-amino-quinolines
US2486440A (en) * 1946-01-10 1949-11-01 Gen Aniline & Film Corp Production of phenazonium dyestuff images
BE502610A (fi) * 1950-04-18
US2888346A (en) * 1955-08-22 1959-05-26 Gen Aniline & Film Corp Ultra-violet absorbing compounds
DE1049701B (fi) * 1957-02-21
FR6592M (fi) * 1967-10-31 1968-12-30
BE794945A (fr) * 1972-02-04 1973-08-02 Sandoz Sa Application de derives de la quinoleine pour stabiliser des matieres organiques contre les effets de la lumiere ultraviolette
US4009020A (en) * 1975-05-06 1977-02-22 Amchem Products, Inc. Method of regulating plant growth
SU1109402A1 (ru) * 1982-10-12 1984-08-23 Предприятие П/Я Р-6496 Способ получени производных 2-(хинолил-4)-5-арилоксазола
ZA845594B (en) * 1983-07-22 1986-03-26 Du Pont Phenylquinolinecarboxylic acids and derivatives as antitumor agents
US4680299A (en) * 1984-04-30 1987-07-14 E.I. Du Pont De Nemours And Company 2-phenyl-4-quinolinecarboxylic acids and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
JPH01110673A (ja) 1989-04-27
JP2760379B2 (ja) 1998-05-28
IL87457A (en) 1994-08-26
FI883997A0 (fi) 1988-08-30
FI883997A (fi) 1989-03-01
DD282225A5 (de) 1990-09-05
PH26258A (en) 1992-04-01
IE882628L (en) 1989-02-28
NO883865L (no) 1989-03-01
EP0305952A1 (en) 1989-03-08
DK482688A (da) 1989-03-01
AU2167888A (en) 1989-03-02
FI92692B (fi) 1994-09-15
CA1333606C (en) 1994-12-20
AR245698A1 (es) 1994-02-28
AU613661B2 (en) 1991-08-08
GR3008033T3 (fi) 1993-09-30
FI92692C (fi) 1994-12-27
KR890003703A (ko) 1989-04-17
NO883865D0 (no) 1988-08-30
CS587588A2 (en) 1990-06-13
ATE90079T1 (de) 1993-06-15
PT88365A (pt) 1989-06-30
ES2058191T3 (es) 1994-11-01
US4847381A (en) 1989-07-11
PL156232B1 (en) 1992-02-28
EP0305952B1 (en) 1993-06-02
HUT48597A (en) 1989-06-28
CS274434B2 (en) 1991-04-11
DE3881456T2 (de) 1994-01-13
DE3881456D1 (de) 1993-07-08
PL274471A1 (en) 1989-05-02
KR970005909B1 (ko) 1997-04-22
PT88365B (pt) 1995-03-31
DK169473B1 (da) 1994-11-07
NZ225924A (en) 1991-07-26
IE65148B1 (en) 1995-10-04
HU202498B (en) 1991-03-28
IL87457A0 (en) 1989-01-31
NO174961C (no) 1994-08-10
NO174961B (no) 1994-05-02
DK482688D0 (da) 1988-08-30

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