ZA885967B - Elaboration of host defense mediators into biological fluids by systemic dsrna treatment - Google Patents

Elaboration of host defense mediators into biological fluids by systemic dsrna treatment

Info

Publication number
ZA885967B
ZA885967B ZA885967A ZA885967A ZA885967B ZA 885967 B ZA885967 B ZA 885967B ZA 885967 A ZA885967 A ZA 885967A ZA 885967 A ZA885967 A ZA 885967A ZA 885967 B ZA885967 B ZA 885967B
Authority
ZA
South Africa
Prior art keywords
biological fluids
elaboration
host defense
various
systemic
Prior art date
Application number
ZA885967A
Other languages
English (en)
Inventor
William A Carter
A Carter William
Original Assignee
Hem Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hem Res Inc filed Critical Hem Res Inc
Publication of ZA885967B publication Critical patent/ZA885967B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
ZA885967A 1987-08-12 1988-08-12 Elaboration of host defense mediators into biological fluids by systemic dsrna treatment ZA885967B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8422787A 1987-08-12 1987-08-12

Publications (1)

Publication Number Publication Date
ZA885967B true ZA885967B (en) 1989-07-26

Family

ID=22183617

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA885967A ZA885967B (en) 1987-08-12 1988-08-12 Elaboration of host defense mediators into biological fluids by systemic dsrna treatment

Country Status (19)

Country Link
EP (1) EP0308066B1 (hu)
JP (1) JPH01131119A (hu)
KR (1) KR0131879B1 (hu)
CN (1) CN1050995C (hu)
AT (1) ATE132041T1 (hu)
AU (3) AU2053588A (hu)
CA (1) CA1327002C (hu)
DE (1) DE3854829T2 (hu)
DK (1) DK449888A (hu)
FI (1) FI883763A (hu)
HU (1) HUT47854A (hu)
IE (1) IE72103B1 (hu)
IL (1) IL87413A0 (hu)
NO (1) NO883594L (hu)
NZ (1) NZ225799A (hu)
OA (1) OA08901A (hu)
PT (1) PT88266B (hu)
RU (1) RU1834663C (hu)
ZA (1) ZA885967B (hu)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE122402T1 (de) * 1987-09-04 1995-05-15 Hem Pharma Corp Diagnose von mangelzuständen doppelsträngiger rns.
US5593973A (en) * 1987-09-04 1997-01-14 Hemispherx Biopharma Inc. Treatment of viral hepatitis with mismatched dsRNA
US4963532A (en) * 1987-11-25 1990-10-16 Hem Research, Inc. dsRNA-based prevention of viral escape
EP0378621A4 (en) * 1988-05-23 1991-08-28 Steffen Gay Diagnostics and therapy for rheumatoid arthritis
EP0473576A4 (en) * 1989-05-19 1993-03-10 Hem Research, Inc. Short therapeutic dsrna of defined structure
ZA908037B (en) * 1989-10-11 1991-09-25 Hem Res Inc Protection from shock subsequent to injury by double-standed rnas
JP3150967B2 (ja) * 1989-10-11 2001-03-26 エイチイーエム リサーチ，インコーポレイティド 二本鎖ｒｎａによる損傷に続くショックからの保護
AU647754B2 (en) * 1989-10-16 1994-03-31 Hem Research, Inc. Diagnosis and treatment of neuro-cognitive disorders associated with systemic immunological malfunction
EP0654998A1 (en) * 1991-09-26 1995-05-31 Hem Pharmaceuticals Corp. METHOD OF NEUTRALIZING IL-1 USING dsRNAs
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
EP1857549B1 (en) 1998-03-20 2018-10-17 Commonwealth Scientific and Industrial Research Organisation Control of gene expression
AUPP249298A0 (en) 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
EP1147204A1 (en) 1999-01-28 2001-10-24 Medical College Of Georgia Research Institute, Inc. Composition and method for in vivo and in vitro attenuation of gene expression using double stranded rna
US6423885B1 (en) 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
US7638496B2 (en) 2000-02-15 2009-12-29 Valeant Pharmaceuticals North America Nucleoside analogs with carboxamidine modified monocyclic base
CA2369944A1 (en) 2001-01-31 2002-07-31 Nucleonics Inc. Use of post-transcriptional gene silencing for identifying nucleic acid sequences that modulate the function of a cell
WO2003087367A2 (en) * 2002-04-18 2003-10-23 Lynkeus Biotech Gmbh Means and methods for the specific inhibition of genes in cells and tissue of the cns and/or eye
US7148342B2 (en) 2002-07-24 2006-12-12 The Trustees Of The University Of Pennyslvania Compositions and methods for sirna inhibition of angiogenesis
AU2003260489A1 (en) 2002-09-04 2004-03-29 Novartis Ag Treatment of neurological disorders by dsrna adminitration
JP2010520284A (ja) * 2007-03-05 2010-06-10 ユタ ステイト ユニバーシティ Ｔｏｌｌ様受容体３（ＴＬＲ３）の限定アゴニスト
CA2745832A1 (en) 2008-12-04 2010-06-10 Opko Ophthalmics, Llc Compositions and methods for selective inhibition of pro-angiogenic vegf isoforms
CN109355334A (zh) * 2018-12-06 2019-02-19 江苏省农业科学院 一种制备聚肌胞的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1326450C (en) * 1985-08-26 1994-01-25 William A. Carter Modulation of aids virus-related events by double stranded rnas (dsrnas)
AU1820388A (en) * 1987-07-17 1989-01-19 Hem Research, Inc. Double stranded rna correction of aberrant metabolic pathways associated with uncontrolled tumor cell and virus growth cycles

Also Published As

Publication number Publication date
CA1327002C (en) 1994-02-15
DE3854829T2 (de) 1996-08-14
IL87413A0 (en) 1989-01-31
CN1050995C (zh) 2000-04-05
IE882399L (en) 1989-02-12
AU1736792A (en) 1992-07-30
DK449888A (da) 1989-02-13
ATE132041T1 (de) 1996-01-15
DE3854829D1 (de) 1996-02-08
EP0308066A2 (en) 1989-03-22
EP0308066B1 (en) 1995-12-27
IE72103B1 (en) 1997-03-12
KR0131879B1 (ko) 1998-04-17
OA08901A (en) 1989-10-31
FI883763A0 (fi) 1988-08-12
KR890003402A (ko) 1989-04-14
PT88266A (pt) 1989-06-30
AU2053588A (en) 1989-04-20
PT88266B (pt) 1995-05-04
NO883594L (no) 1989-02-13
NO883594D0 (no) 1988-08-12
DK449888D0 (da) 1988-08-11
AU1001595A (en) 1995-02-23
JPH01131119A (ja) 1989-05-24
HUT47854A (en) 1989-04-28
FI883763A (fi) 1989-02-13
RU1834663C (ru) 1993-08-15
EP0308066A3 (en) 1991-01-16
CN1032740A (zh) 1989-05-10
NZ225799A (en) 1991-04-26

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