ATE122402T1 - Diagnose von mangelzuständen doppelsträngiger rns. - Google Patents

Diagnose von mangelzuständen doppelsträngiger rns.

Info

Publication number
ATE122402T1
ATE122402T1 AT88308187T AT88308187T ATE122402T1 AT E122402 T1 ATE122402 T1 AT E122402T1 AT 88308187 T AT88308187 T AT 88308187T AT 88308187 T AT88308187 T AT 88308187T AT E122402 T1 ATE122402 T1 AT E122402T1
Authority
AT
Austria
Prior art keywords
double
stranded rna
deficiencies
diagnosis
dsrna
Prior art date
Application number
AT88308187T
Other languages
English (en)
Inventor
William A Carter
Original Assignee
Hem Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hem Pharma Corp filed Critical Hem Pharma Corp
Application granted granted Critical
Publication of ATE122402T1 publication Critical patent/ATE122402T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
AT88308187T 1987-09-04 1988-09-05 Diagnose von mangelzuständen doppelsträngiger rns. ATE122402T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9352387A 1987-09-04 1987-09-04
US22076588A 1988-07-07 1988-07-07
US23701988A 1988-08-29 1988-08-29

Publications (1)

Publication Number Publication Date
ATE122402T1 true ATE122402T1 (de) 1995-05-15

Family

ID=27377535

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88308187T ATE122402T1 (de) 1987-09-04 1988-09-05 Diagnose von mangelzuständen doppelsträngiger rns.

Country Status (3)

Country Link
EP (1) EP0306347B1 (de)
AT (1) ATE122402T1 (de)
DE (1) DE3853755T2 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68914201T2 (de) * 1988-07-07 1994-07-14 Hem Pharma Corp Diagnose und Behandlung chronischer Ermüdungserscheinungen.
US5258369A (en) * 1988-08-29 1993-11-02 Hem Pharmaceuticals Corporation Treatment of chronic cerebral dysfunction by dsRNA methodology
EP0473576A4 (en) * 1989-05-19 1993-03-10 Hem Research, Inc. Short therapeutic dsrna of defined structure
WO1991000097A1 (en) * 1989-06-27 1991-01-10 Hem Research, Inc. Diagnosing and treating viral infections associated with chronic fatigue
ZA908037B (en) * 1989-10-11 1991-09-25 Hem Res Inc Protection from shock subsequent to injury by double-standed rnas
EP0495919B1 (de) * 1989-10-11 1997-01-15 Hem Pharmaceuticals Corp. Schutz gegen schock infolge einer schädigung durch doppelsträngige rna's
AU647754B2 (en) * 1989-10-16 1994-03-31 Hem Research, Inc. Diagnosis and treatment of neuro-cognitive disorders associated with systemic immunological malfunction
US5132292A (en) * 1990-05-25 1992-07-21 Hem Research, Inc. Treatment of viral hepatitis
CA2120027A1 (en) * 1991-09-26 1993-04-01 William A. Carter Method of neutralizing il-1 using dsrnas
US5985565A (en) * 1996-10-09 1999-11-16 Temple University-Of The Commonwealth System Of Higher Education Chronic fatigue syndrome diagnosis
FR2768345B1 (fr) * 1997-09-17 2001-05-04 Scras Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale, notamment d'une hepatite virale
FR2768344B1 (fr) * 1997-08-26 2001-02-16 Scras Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale
FR2766715B1 (fr) * 1997-08-04 2001-02-16 Scras Produit comprenant au moins de l'arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique simultanee, separee ou etalee dans le temps, dans le traitement d'une maladie virale
TW589189B (en) * 1997-08-04 2004-06-01 Scras Kit containing at least one double-stranded RNA combined with at least one anti-viral agent for therapeutic use in the treatment of a viral disease, notably of viral hepatitis
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
CN1796556A (zh) 1998-03-20 2006-07-05 联邦科学和工业研究组织 控制基因表达
AUPP249298A0 (en) 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
EP1147204A1 (de) 1999-01-28 2001-10-24 Medical College Of Georgia Research Institute, Inc. Zusammensetzung und verfahren zur in vivo und in vitro abschwächung der genexpression mittels dobbelsträngigem rna
US6207366B1 (en) 1999-04-14 2001-03-27 Temple University- Of The Commonwealth System Of Higher Education Chronic fatigue syndrome diagnosis
US6423885B1 (en) 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
EP1229134A3 (de) 2001-01-31 2004-01-28 Nucleonics, Inc Verwendung von post-transkriptioneller Genabschaltung zur Identifizierung von Nukleinsäuresequenzen die die Funktion einer Zelle beeinflussen
EP2405919A4 (de) * 2009-03-13 2013-01-02 Hemispherx Biopharma Inc Behandlung von chronischem erschöpfungssyndrom und verlängertem qt-intervall

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1326450C (en) * 1985-08-26 1994-01-25 William A. Carter Modulation of aids virus-related events by double stranded rnas (dsrnas)
PH30882A (en) * 1987-03-03 1997-12-23 Hem Res Inc Activated Rnase L as a maker for viral infections.
AU1820388A (en) * 1987-07-17 1989-01-19 Hem Research, Inc. Double stranded rna correction of aberrant metabolic pathways associated with uncontrolled tumor cell and virus growth cycles
IE72103B1 (en) * 1987-08-12 1997-03-12 Hem Res Inc Promotion of host defense by systemic dsRNA treatment

Also Published As

Publication number Publication date
EP0306347B1 (de) 1995-05-10
DE3853755T2 (de) 1995-12-14
DE3853755D1 (de) 1995-06-14
EP0306347A3 (en) 1990-10-03
EP0306347A2 (de) 1989-03-08

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee