DE3853755T2 - Diagnose von Mangelzuständen doppelsträngiger RNS. - Google Patents
Diagnose von Mangelzuständen doppelsträngiger RNS.Info
- Publication number
- DE3853755T2 DE3853755T2 DE3853755T DE3853755T DE3853755T2 DE 3853755 T2 DE3853755 T2 DE 3853755T2 DE 3853755 T DE3853755 T DE 3853755T DE 3853755 T DE3853755 T DE 3853755T DE 3853755 T2 DE3853755 T2 DE 3853755T2
- Authority
- DE
- Germany
- Prior art keywords
- double
- stranded rna
- diagnosis
- deficiency states
- dsrna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9352387A | 1987-09-04 | 1987-09-04 | |
US22076588A | 1988-07-07 | 1988-07-07 | |
US23701988A | 1988-08-29 | 1988-08-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3853755D1 DE3853755D1 (de) | 1995-06-14 |
DE3853755T2 true DE3853755T2 (de) | 1995-12-14 |
Family
ID=27377535
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3853755T Expired - Fee Related DE3853755T2 (de) | 1987-09-04 | 1988-09-05 | Diagnose von Mangelzuständen doppelsträngiger RNS. |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0306347B1 (de) |
AT (1) | ATE122402T1 (de) |
DE (1) | DE3853755T2 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0350151B1 (de) * | 1988-07-07 | 1994-03-30 | Hem Pharmaceuticals Corp. | Diagnose und Behandlung chronischer Ermüdungserscheinungen |
US5258369A (en) * | 1988-08-29 | 1993-11-02 | Hem Pharmaceuticals Corporation | Treatment of chronic cerebral dysfunction by dsRNA methodology |
JPH04507083A (ja) * | 1989-05-19 | 1992-12-10 | ヘム・リサーチ・インコーポレーテッド | 規定された構造の短い治療用dsRNA |
WO1991000097A1 (en) * | 1989-06-27 | 1991-01-10 | Hem Research, Inc. | Diagnosing and treating viral infections associated with chronic fatigue |
ZA908037B (en) * | 1989-10-11 | 1991-09-25 | Hem Res Inc | Protection from shock subsequent to injury by double-standed rnas |
EP0495919B1 (de) * | 1989-10-11 | 1997-01-15 | Hem Pharmaceuticals Corp. | Schutz gegen schock infolge einer schädigung durch doppelsträngige rna's |
EP0495831B1 (de) * | 1989-10-16 | 1997-01-15 | Hem Pharmaceuticals Corp. | Diagnose und behandlung von neuro-cognitiven störungen assoziiert mit systemisch-immunologischer fehlfunktion |
US5132292A (en) * | 1990-05-25 | 1992-07-21 | Hem Research, Inc. | Treatment of viral hepatitis |
CA2120027A1 (en) * | 1991-09-26 | 1993-04-01 | William A. Carter | Method of neutralizing il-1 using dsrnas |
US5985565A (en) | 1996-10-09 | 1999-11-16 | Temple University-Of The Commonwealth System Of Higher Education | Chronic fatigue syndrome diagnosis |
FR2768344B1 (fr) * | 1997-08-26 | 2001-02-16 | Scras | Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale |
FR2768345B1 (fr) * | 1997-09-17 | 2001-05-04 | Scras | Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale, notamment d'une hepatite virale |
TW589189B (en) * | 1997-08-04 | 2004-06-01 | Scras | Kit containing at least one double-stranded RNA combined with at least one anti-viral agent for therapeutic use in the treatment of a viral disease, notably of viral hepatitis |
FR2766715B1 (fr) * | 1997-08-04 | 2001-02-16 | Scras | Produit comprenant au moins de l'arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique simultanee, separee ou etalee dans le temps, dans le traitement d'une maladie virale |
US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
AUPP249298A0 (en) | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
CA2487328A1 (en) | 1998-03-20 | 1999-09-30 | Benitec Australia Ltd. | Sirna for control of gene expression |
EP2314700A1 (de) | 1999-01-28 | 2011-04-27 | Medical College of Georgia Research Institute, Inc | Zusammensetzung und Verfahren zur in vivo und in vitro Abschwächung der Genexpression mittels dobbelsträngiger RNA |
US6207366B1 (en) | 1999-04-14 | 2001-03-27 | Temple University- Of The Commonwealth System Of Higher Education | Chronic fatigue syndrome diagnosis |
US6423885B1 (en) | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
US20020132257A1 (en) | 2001-01-31 | 2002-09-19 | Tony Giordano | Use of post-transcriptional gene silencing for identifying nucleic acid sequences that modulate the function of a cell |
EP2405919A4 (de) * | 2009-03-13 | 2013-01-02 | Hemispherx Biopharma Inc | Behandlung von chronischem erschöpfungssyndrom und verlängertem qt-intervall |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1326450C (en) * | 1985-08-26 | 1994-01-25 | William A. Carter | Modulation of aids virus-related events by double stranded rnas (dsrnas) |
PH30882A (en) * | 1987-03-03 | 1997-12-23 | Hem Res Inc | Activated Rnase L as a maker for viral infections. |
AU1820388A (en) * | 1987-07-17 | 1989-01-19 | Hem Research, Inc. | Double stranded rna correction of aberrant metabolic pathways associated with uncontrolled tumor cell and virus growth cycles |
IE72103B1 (en) * | 1987-08-12 | 1997-03-12 | Hem Res Inc | Promotion of host defense by systemic dsRNA treatment |
-
1988
- 1988-09-05 EP EP88308187A patent/EP0306347B1/de not_active Expired - Lifetime
- 1988-09-05 AT AT88308187T patent/ATE122402T1/de not_active IP Right Cessation
- 1988-09-05 DE DE3853755T patent/DE3853755T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0306347B1 (de) | 1995-05-10 |
DE3853755D1 (de) | 1995-06-14 |
ATE122402T1 (de) | 1995-05-15 |
EP0306347A2 (de) | 1989-03-08 |
EP0306347A3 (en) | 1990-10-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |