ZA881258B - Stable interferon complexes - Google Patents

Stable interferon complexes

Info

Publication number
ZA881258B
ZA881258B ZA881258A ZA881258A ZA881258B ZA 881258 B ZA881258 B ZA 881258B ZA 881258 A ZA881258 A ZA 881258A ZA 881258 A ZA881258 A ZA 881258A ZA 881258 B ZA881258 B ZA 881258B
Authority
ZA
South Africa
Prior art keywords
stable interferon
interferon complexes
complexes
alpha interferon
stable
Prior art date
Application number
ZA881258A
Other languages
English (en)
Inventor
Yim Zachary
A. Zupon Michael
A. Chaudry Imtiaz
Original Assignee
Schering Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corporation filed Critical Schering Corporation
Publication of ZA881258B publication Critical patent/ZA881258B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
ZA881258A 1987-02-24 1988-02-23 Stable interferon complexes ZA881258B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/018,243 US4853218A (en) 1987-02-24 1987-02-24 Zinc-protamine-alpha interferon complex

Publications (1)

Publication Number Publication Date
ZA881258B true ZA881258B (en) 1988-08-23

Family

ID=21786960

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA881258A ZA881258B (en) 1987-02-24 1988-02-23 Stable interferon complexes

Country Status (23)

Country Link
US (1) US4853218A (fi)
EP (2) EP0281299B1 (fi)
JP (1) JPH0611712B2 (fi)
KR (1) KR940001372B1 (fi)
AT (1) ATE76580T1 (fi)
AU (1) AU608584B2 (fi)
CA (1) CA1316105C (fi)
DE (1) DE3871407D1 (fi)
DK (1) DK167048B1 (fi)
ES (1) ES2032009T3 (fi)
FI (1) FI93309C (fi)
GR (1) GR3005358T3 (fi)
HU (1) HU201881B (fi)
IE (1) IE61340B1 (fi)
IL (1) IL85523A (fi)
MX (1) MX9203328A (fi)
MY (1) MY103212A (fi)
NO (1) NO173279C (fi)
NZ (1) NZ223598A (fi)
OA (1) OA09737A (fi)
PT (1) PT86810B (fi)
WO (1) WO1988006456A1 (fi)
ZA (1) ZA881258B (fi)

Families Citing this family (42)

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US5028422A (en) * 1986-05-27 1991-07-02 Schering Corporation Treatment of basal cell carcinoma intralesionally with recombinant human alpha interferon
PH26198A (en) * 1986-05-27 1992-03-18 Schering Corp Treatment of basal cell carcinoma intralesionally with recombinant human alpha interferon
ES2054815T3 (es) * 1987-09-08 1994-08-16 Takeda Chemical Industries Ltd Citoquinas insolubilizadas en agua.
CA2084406A1 (en) * 1990-06-04 1991-12-05 Paul Reichert Method for preparing interferon alpha-2 crystals
US5912015A (en) * 1992-03-12 1999-06-15 Alkermes Controlled Therapeutics, Inc. Modulated release from biocompatible polymers
US6514533B1 (en) 1992-06-11 2003-02-04 Alkermas Controlled Therapeutics, Inc. Device for the sustained release of aggregation-stabilized, biologically active agent
US5711968A (en) 1994-07-25 1998-01-27 Alkermes Controlled Therapeutics, Inc. Composition and method for the controlled release of metal cation-stabilized interferon
CA2150803C (en) * 1992-12-02 2006-01-31 Henry Auer Controlled release growth hormone containing microspheres
US5441734A (en) * 1993-02-25 1995-08-15 Schering Corporation Metal-interferon-alpha crystals
US6087324A (en) * 1993-06-24 2000-07-11 Takeda Chemical Industries, Ltd. Sustained-release preparation
AU706180B2 (en) * 1994-07-25 1999-06-10 Alkermes Controlled Therapeutics, Inc. Controlled release of metal cation-stabilized interferon
US5904935A (en) * 1995-06-07 1999-05-18 Alza Corporation Peptide/protein suspending formulations
JP3837769B2 (ja) * 1995-06-12 2006-10-25 大塚製薬株式会社 抗ウイルス剤
AU710347B2 (en) * 1995-08-31 1999-09-16 Alkermes Controlled Therapeutics, Inc. Composition for sustained release of an agent
CN1146402C (zh) * 1996-12-20 2004-04-21 阿尔萨公司 凝胶组合物及方法
US6465425B1 (en) 2000-02-10 2002-10-15 Alkermes Controlled Therapeutics, Inc. Microencapsulation and sustained release of biologically active acid-stable or free sulfhydryl-containing proteins
US20030211974A1 (en) * 2000-03-21 2003-11-13 Brodbeck Kevin J. Gel composition and methods
CA2466642C (en) * 2001-11-14 2011-01-18 Guohua Chen Injectable depot composition
NZ533435A (en) * 2001-11-14 2007-10-26 Alza Corp Injectable depot compositions and uses thereof
WO2003041757A2 (en) * 2001-11-14 2003-05-22 Alza Corporation Catheter injectable depot compositions and uses thereof
US20070196415A1 (en) * 2002-11-14 2007-08-23 Guohua Chen Depot compositions with multiple drug release rate controls and uses thereof
TWI353854B (en) 2002-06-25 2011-12-11 Alza Corp Short duration depot formulations
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
JP4639400B2 (ja) 2002-07-31 2011-02-23 デュレクト コーポレイション 注入可能な多モードポリマーのデポ組成物及びその使用
JP2006503004A (ja) * 2002-07-31 2006-01-26 アルザ・コーポレーション 射出可能なデポ組成物及びその使用
JP2006508127A (ja) * 2002-11-06 2006-03-09 アルザ・コーポレーション 制御された放出性デポー剤配合物
CA2512052C (en) * 2002-12-31 2016-06-21 Altus Pharmaceuticals Inc. Human growth hormone crystals and methods for preparing them
KR20050094832A (ko) * 2002-12-31 2005-09-28 알투스 파마슈티컬스 인코포레이티드 단백질 결정과 이온성 중합체를 함유하는 복합체
US20070184084A1 (en) * 2003-05-30 2007-08-09 Guohua Chen Implantable elastomeric caprolactone depot compositions and uses thereof
EP1643968A1 (en) * 2003-05-30 2006-04-12 ALZA Corporation Implantable elastomeric depot compositions, uses thereof and method of manufacturing
US20050106214A1 (en) * 2003-11-14 2005-05-19 Guohua Chen Excipients in drug delivery vehicles
US20050281879A1 (en) * 2003-11-14 2005-12-22 Guohua Chen Excipients in drug delivery vehicles
US7812049B2 (en) * 2004-01-22 2010-10-12 Vicept Therapeutics, Inc. Method and therapeutic/cosmetic topical compositions for the treatment of rosacea and skin erythema using α1-adrenoceptor agonists
US20060142234A1 (en) * 2004-12-23 2006-06-29 Guohua Chen Injectable non-aqueous suspension
CA2634053A1 (en) * 2005-12-23 2007-07-05 Altus Pharmaceuticals Inc. Compositions comprising polycation-complexed protein crystals and methods of treatment using them
US7753078B2 (en) 2007-04-19 2010-07-13 Husco International Inc. Hybrid hydraulic joystick with an integral pressure sensor and an outlet port
US7753077B2 (en) 2007-04-19 2010-07-13 Husco International Inc. Hybrid hydraulic joystick for electrically operating valves
JP4889782B2 (ja) * 2008-12-24 2012-03-07 株式会社マルハニチロ食品 プロタミン及び／またはその塩と酸性高分子化合物とを含む生理活性複合体及びその用途
WO2010088294A1 (en) * 2009-01-28 2010-08-05 Smartcells, Inc. Conjugate based systems for controlled drug delivery
MX347014B (es) * 2010-11-24 2017-04-07 Durect Corp Composición para administración de fármaco biodegradable.
WO2015088990A1 (en) 2013-12-09 2015-06-18 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
JP2023515918A (ja) 2020-01-13 2023-04-17 デュレクト コーポレーション 不純物が低減された徐放性薬物送達システム及び関連の方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1282504A (fr) * 1954-06-03 1962-01-27 Novo Terapeutisk Labor As Procédé de production de suspensions stables d'insuline zinc-protamine
US3912807A (en) * 1974-04-18 1975-10-14 American Home Prod Treatment of diabetes using somatostatin and insulin
IN150740B (fi) * 1978-11-24 1982-12-04 Hoffmann La Roche
AU553400B2 (en) * 1980-01-08 1986-07-17 Biogen, Inc. Recombinant dna for producing interferon
ES506955A0 (es) * 1980-11-10 1983-02-01 Genentech Inc Un procedimiento para producir un polipeptido antiviral.
DE3262575D1 (en) * 1981-12-23 1985-04-18 Schering Corp Stabilised interferon formulations and their preparation
US4605555A (en) * 1984-09-20 1986-08-12 Sun Star Kabushiki Kaisha Composition and method for treating keratosic disorder of skin and mucosa

Also Published As

Publication number Publication date
IE61340B1 (en) 1994-11-02
CA1316105C (en) 1993-04-13
NO884596D0 (no) 1988-10-14
DK582188D0 (da) 1988-10-19
NO173279C (no) 1993-11-24
FI893929A (fi) 1989-08-22
DE3871407D1 (de) 1992-07-02
KR890700359A (ko) 1989-04-24
US4853218A (en) 1989-08-01
MY103212A (en) 1993-05-29
ES2032009T3 (es) 1993-01-01
EP0281299B1 (en) 1992-05-27
IL85523A (en) 1992-11-15
HU201881B (en) 1991-01-28
IL85523A0 (en) 1988-08-31
PT86810A (pt) 1988-03-01
NZ223598A (en) 1989-12-21
EP0281299A1 (en) 1988-09-07
FI93309C (fi) 1995-03-27
AU608584B2 (en) 1991-04-11
FI893929A0 (fi) 1989-08-22
KR940001372B1 (ko) 1994-02-21
GR3005358T3 (fi) 1993-05-24
IE880480L (en) 1988-08-24
FI93309B (fi) 1994-12-15
AU1394688A (en) 1988-09-26
OA09737A (en) 1993-11-30
JPH03500286A (ja) 1991-01-24
ATE76580T1 (de) 1992-06-15
DK167048B1 (da) 1993-08-23
WO1988006456A1 (en) 1988-09-07
EP0375678A1 (en) 1990-07-04
DK582188A (da) 1988-10-19
NO884596L (no) 1988-10-14
NO173279B (no) 1993-08-16
PT86810B (pt) 1992-05-29
MX9203328A (es) 1992-07-01
HUT51902A (en) 1990-06-28
JPH0611712B2 (ja) 1994-02-16

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