ZA881258B - Stable interferon complexes - Google Patents

Stable interferon complexes

Info

Publication number
ZA881258B
ZA881258B ZA881258A ZA881258A ZA881258B ZA 881258 B ZA881258 B ZA 881258B ZA 881258 A ZA881258 A ZA 881258A ZA 881258 A ZA881258 A ZA 881258A ZA 881258 B ZA881258 B ZA 881258B
Authority
ZA
South Africa
Prior art keywords
stable interferon
interferon complexes
complexes
alpha interferon
stable
Prior art date
Application number
ZA881258A
Other languages
English (en)
Inventor
Yim Zachary
A. Zupon Michael
A. Chaudry Imtiaz
Original Assignee
Schering Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corporation filed Critical Schering Corporation
Publication of ZA881258B publication Critical patent/ZA881258B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA881258A 1987-02-24 1988-02-23 Stable interferon complexes ZA881258B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/018,243 US4853218A (en) 1987-02-24 1987-02-24 Zinc-protamine-alpha interferon complex

Publications (1)

Publication Number Publication Date
ZA881258B true ZA881258B (en) 1988-08-23

Family

ID=21786960

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA881258A ZA881258B (en) 1987-02-24 1988-02-23 Stable interferon complexes

Country Status (23)

Country Link
US (1) US4853218A (xx)
EP (2) EP0281299B1 (xx)
JP (1) JPH0611712B2 (xx)
KR (1) KR940001372B1 (xx)
AT (1) ATE76580T1 (xx)
AU (1) AU608584B2 (xx)
CA (1) CA1316105C (xx)
DE (1) DE3871407D1 (xx)
DK (1) DK167048B1 (xx)
ES (1) ES2032009T3 (xx)
FI (1) FI93309C (xx)
GR (1) GR3005358T3 (xx)
HU (1) HU201881B (xx)
IE (1) IE61340B1 (xx)
IL (1) IL85523A (xx)
MX (1) MX9203328A (xx)
MY (1) MY103212A (xx)
NO (1) NO173279C (xx)
NZ (1) NZ223598A (xx)
OA (1) OA09737A (xx)
PT (1) PT86810B (xx)
WO (1) WO1988006456A1 (xx)
ZA (1) ZA881258B (xx)

Families Citing this family (42)

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Publication number Priority date Publication date Assignee Title
DK264787A (da) * 1986-05-27 1987-11-28 Schering Corp Anvendelse af humant alfa-interferon til fremstilling af et pharmaceutisk praeparat
US5028422A (en) * 1986-05-27 1991-07-02 Schering Corporation Treatment of basal cell carcinoma intralesionally with recombinant human alpha interferon
EP0307097B1 (en) * 1987-09-08 1993-06-09 Takeda Chemical Industries, Ltd. Water-insolubilized cytokines
SG45207A1 (en) * 1990-06-04 1998-01-16 Schering Corp Method for preparing interferon alpha-2 crystals
US5912015A (en) 1992-03-12 1999-06-15 Alkermes Controlled Therapeutics, Inc. Modulated release from biocompatible polymers
US6514533B1 (en) 1992-06-11 2003-02-04 Alkermas Controlled Therapeutics, Inc. Device for the sustained release of aggregation-stabilized, biologically active agent
US5711968A (en) * 1994-07-25 1998-01-27 Alkermes Controlled Therapeutics, Inc. Composition and method for the controlled release of metal cation-stabilized interferon
EP1013270A3 (en) * 1992-12-02 2001-03-28 Alkermes Controlled Therapeutics, Inc. Controlled release growth hormone containing microspheres
US5441734A (en) * 1993-02-25 1995-08-15 Schering Corporation Metal-interferon-alpha crystals
US6087324A (en) * 1993-06-24 2000-07-11 Takeda Chemical Industries, Ltd. Sustained-release preparation
AU706180B2 (en) * 1994-07-25 1999-06-10 Alkermes Controlled Therapeutics, Inc. Controlled release of metal cation-stabilized interferon
US5904935A (en) * 1995-06-07 1999-05-18 Alza Corporation Peptide/protein suspending formulations
JP3837769B2 (ja) * 1995-06-12 2006-10-25 大塚製薬株式会社 抗ウイルス剤
CA2230494A1 (en) * 1995-08-31 1997-03-06 Alkermes Controlled Therapeutics Inc. Composition for sustained release of an agent
DE69705746T2 (de) * 1996-12-20 2001-10-31 Alza Corp Injizierbare depotgelzubereitung und herstellungsverfahren
US6465425B1 (en) 2000-02-10 2002-10-15 Alkermes Controlled Therapeutics, Inc. Microencapsulation and sustained release of biologically active acid-stable or free sulfhydryl-containing proteins
US20030211974A1 (en) * 2000-03-21 2003-11-13 Brodbeck Kevin J. Gel composition and methods
IL162001A0 (en) * 2001-11-14 2005-11-20 Alza Corp Catheter injectable depot compositions and uses thereof
WO2003041684A2 (en) * 2001-11-14 2003-05-22 Alza Corporation Injectable depot compositions and uses thereof
US20070196415A1 (en) * 2002-11-14 2007-08-23 Guohua Chen Depot compositions with multiple drug release rate controls and uses thereof
CN100446809C (zh) * 2001-11-14 2008-12-31 阿尔扎有限公司 可注射的长效组合物
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
TWI353854B (en) 2002-06-25 2011-12-11 Alza Corp Short duration depot formulations
BR0313539A (pt) * 2002-07-31 2005-06-21 Alza Corp Composições depósito de polìmero multimodais injetáveis e seus usos
WO2004012703A1 (en) * 2002-07-31 2004-02-12 Alza Corporation Injectable depot compositions and uses thereof
BR0315304A (pt) * 2002-11-06 2005-08-16 Alza Corp Formulações com depósito para liberação controlada
JP2006523609A (ja) * 2002-12-31 2006-10-19 アルタス ファーマシューティカルズ インコーポレイテッド タンパク質結晶およびイオン性ポリマーの複合体
CA2512052C (en) * 2002-12-31 2016-06-21 Altus Pharmaceuticals Inc. Human growth hormone crystals and methods for preparing them
CA2527664A1 (en) * 2003-05-30 2004-12-16 Alza Corporation Implantable elastomeric depot compositions, uses thereof and method of manufacturing
US20070184084A1 (en) * 2003-05-30 2007-08-09 Guohua Chen Implantable elastomeric caprolactone depot compositions and uses thereof
US20050281879A1 (en) * 2003-11-14 2005-12-22 Guohua Chen Excipients in drug delivery vehicles
US20050106214A1 (en) * 2003-11-14 2005-05-19 Guohua Chen Excipients in drug delivery vehicles
US7812049B2 (en) * 2004-01-22 2010-10-12 Vicept Therapeutics, Inc. Method and therapeutic/cosmetic topical compositions for the treatment of rosacea and skin erythema using α1-adrenoceptor agonists
US20060142234A1 (en) * 2004-12-23 2006-06-29 Guohua Chen Injectable non-aqueous suspension
CA2634053A1 (en) * 2005-12-23 2007-07-05 Altus Pharmaceuticals Inc. Compositions comprising polycation-complexed protein crystals and methods of treatment using them
US7753077B2 (en) 2007-04-19 2010-07-13 Husco International Inc. Hybrid hydraulic joystick for electrically operating valves
US7753078B2 (en) 2007-04-19 2010-07-13 Husco International Inc. Hybrid hydraulic joystick with an integral pressure sensor and an outlet port
JP4889782B2 (ja) * 2008-12-24 2012-03-07 株式会社マルハニチロ食品 プロタミン及び／またはその塩と酸性高分子化合物とを含む生理活性複合体及びその用途
MX2011007929A (es) 2009-01-28 2011-08-17 Smartcells Inc Sistemas basados en conjugados para entrega farmacologica controlada.
EP2643009A4 (en) * 2010-11-24 2015-04-01 Durect Corp BIODEGRADABLE DRUG DELIVERY COMPOSITION
EP3079668A1 (en) 2013-12-09 2016-10-19 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
CA3167217A1 (en) 2020-01-13 2021-07-22 Durect Corporation Sustained release drug delivery systems with reduced impurities and related methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1282504A (fr) * 1954-06-03 1962-01-27 Novo Terapeutisk Labor As Procédé de production de suspensions stables d'insuline zinc-protamine
US3912807A (en) * 1974-04-18 1975-10-14 American Home Prod Treatment of diabetes using somatostatin and insulin
IN150740B (xx) * 1978-11-24 1982-12-04 Hoffmann La Roche
DK170236B1 (da) * 1980-01-08 1995-07-10 Biogen Inc Rekombinante DNA-molekyler, fremgangsmåde til fremstilling af et polypeptid af IFN-alfa typen og fremgangsmåde til udvælgelse af DNA-sekvenser, der koder for polypeptider af IFN-alfa typen
ES506955A0 (es) * 1980-11-10 1983-02-01 Genentech Inc Un procedimiento para producir un polipeptido antiviral.
DE3262575D1 (en) * 1981-12-23 1985-04-18 Schering Corp Stabilised interferon formulations and their preparation
US4605555A (en) * 1984-09-20 1986-08-12 Sun Star Kabushiki Kaisha Composition and method for treating keratosic disorder of skin and mucosa

Also Published As

Publication number Publication date
NO884596D0 (no) 1988-10-14
IE61340B1 (en) 1994-11-02
DK582188A (da) 1988-10-19
HUT51902A (en) 1990-06-28
PT86810A (pt) 1988-03-01
EP0375678A1 (en) 1990-07-04
PT86810B (pt) 1992-05-29
US4853218A (en) 1989-08-01
FI893929A (fi) 1989-08-22
IL85523A0 (en) 1988-08-31
ATE76580T1 (de) 1992-06-15
HU201881B (en) 1991-01-28
ES2032009T3 (es) 1993-01-01
EP0281299B1 (en) 1992-05-27
IE880480L (en) 1988-08-24
GR3005358T3 (xx) 1993-05-24
DK582188D0 (da) 1988-10-19
FI93309B (fi) 1994-12-15
MX9203328A (es) 1992-07-01
JPH03500286A (ja) 1991-01-24
JPH0611712B2 (ja) 1994-02-16
FI93309C (fi) 1995-03-27
OA09737A (en) 1993-11-30
KR890700359A (ko) 1989-04-24
KR940001372B1 (ko) 1994-02-21
EP0281299A1 (en) 1988-09-07
MY103212A (en) 1993-05-29
NO884596L (no) 1988-10-14
NO173279B (no) 1993-08-16
CA1316105C (en) 1993-04-13
WO1988006456A1 (en) 1988-09-07
NO173279C (no) 1993-11-24
FI893929A0 (fi) 1989-08-22
DE3871407D1 (de) 1992-07-02
DK167048B1 (da) 1993-08-23
IL85523A (en) 1992-11-15
NZ223598A (en) 1989-12-21
AU1394688A (en) 1988-09-26
AU608584B2 (en) 1991-04-11

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