IL85523A - Stable alpha interferon complex,its preparation and pharmaceutical compositions comprising it - Google Patents

Stable alpha interferon complex,its preparation and pharmaceutical compositions comprising it

Info

Publication number
IL85523A
IL85523A IL85523A IL8552388A IL85523A IL 85523 A IL85523 A IL 85523A IL 85523 A IL85523 A IL 85523A IL 8552388 A IL8552388 A IL 8552388A IL 85523 A IL85523 A IL 85523A
Authority
IL
Israel
Prior art keywords
alpha interferon
preparation
pharmaceutical compositions
stable alpha
interferon complex
Prior art date
Application number
IL85523A
Other languages
English (en)
Other versions
IL85523A0 (en
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL85523A0 publication Critical patent/IL85523A0/xx
Publication of IL85523A publication Critical patent/IL85523A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
IL85523A 1987-02-24 1988-02-23 Stable alpha interferon complex,its preparation and pharmaceutical compositions comprising it IL85523A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/018,243 US4853218A (en) 1987-02-24 1987-02-24 Zinc-protamine-alpha interferon complex

Publications (2)

Publication Number Publication Date
IL85523A0 IL85523A0 (en) 1988-08-31
IL85523A true IL85523A (en) 1992-11-15

Family

ID=21786960

Family Applications (1)

Application Number Title Priority Date Filing Date
IL85523A IL85523A (en) 1987-02-24 1988-02-23 Stable alpha interferon complex,its preparation and pharmaceutical compositions comprising it

Country Status (23)

Country Link
US (1) US4853218A (fi)
EP (2) EP0375678A1 (fi)
JP (1) JPH0611712B2 (fi)
KR (1) KR940001372B1 (fi)
AT (1) ATE76580T1 (fi)
AU (1) AU608584B2 (fi)
CA (1) CA1316105C (fi)
DE (1) DE3871407D1 (fi)
DK (1) DK167048B1 (fi)
ES (1) ES2032009T3 (fi)
FI (1) FI93309C (fi)
GR (1) GR3005358T3 (fi)
HU (1) HU201881B (fi)
IE (1) IE61340B1 (fi)
IL (1) IL85523A (fi)
MX (1) MX9203328A (fi)
MY (1) MY103212A (fi)
NO (1) NO173279C (fi)
NZ (1) NZ223598A (fi)
OA (1) OA09737A (fi)
PT (1) PT86810B (fi)
WO (1) WO1988006456A1 (fi)
ZA (1) ZA881258B (fi)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU601741B2 (en) * 1986-05-27 1990-09-20 Schering Corporation Treatment of basal cell carcinoma intralesionally with recombinant human alpha interferon
US5028422A (en) * 1986-05-27 1991-07-02 Schering Corporation Treatment of basal cell carcinoma intralesionally with recombinant human alpha interferon
ES2054815T3 (es) * 1987-09-08 1994-08-16 Takeda Chemical Industries Ltd Citoquinas insolubilizadas en agua.
WO1991018927A1 (en) * 1990-06-04 1991-12-12 Schering Corporation Method for preparing interferon alpha-2 crystals
US5912015A (en) * 1992-03-12 1999-06-15 Alkermes Controlled Therapeutics, Inc. Modulated release from biocompatible polymers
US6514533B1 (en) 1992-06-11 2003-02-04 Alkermas Controlled Therapeutics, Inc. Device for the sustained release of aggregation-stabilized, biologically active agent
US5711968A (en) * 1994-07-25 1998-01-27 Alkermes Controlled Therapeutics, Inc. Composition and method for the controlled release of metal cation-stabilized interferon
EP0674506B1 (en) * 1992-12-02 2000-08-23 Alkermes Controlled Therapeutics, Inc. Controlled release growth hormone containing microspheres
US5441734A (en) * 1993-02-25 1995-08-15 Schering Corporation Metal-interferon-alpha crystals
US6087324A (en) * 1993-06-24 2000-07-11 Takeda Chemical Industries, Ltd. Sustained-release preparation
AU706180B2 (en) * 1994-07-25 1999-06-10 Alkermes Controlled Therapeutics, Inc. Controlled release of metal cation-stabilized interferon
US5904935A (en) * 1995-06-07 1999-05-18 Alza Corporation Peptide/protein suspending formulations
JP3837769B2 (ja) * 1995-06-12 2006-10-25 大塚製薬株式会社 抗ウイルス剤
WO1997007788A2 (en) * 1995-08-31 1997-03-06 Alkermes Controlled Therapeutics, Inc. Composition for sustained release of an agent
PT949905E (pt) * 1996-12-20 2001-12-28 Alza Corp Composicao de gel injectavel de efeito retardado e processo para a sua preparacao
US6465425B1 (en) 2000-02-10 2002-10-15 Alkermes Controlled Therapeutics, Inc. Microencapsulation and sustained release of biologically active acid-stable or free sulfhydryl-containing proteins
US20030211974A1 (en) * 2000-03-21 2003-11-13 Brodbeck Kevin J. Gel composition and methods
CN100446809C (zh) * 2001-11-14 2008-12-31 阿尔扎有限公司 可注射的长效组合物
KR20040058101A (ko) * 2001-11-14 2004-07-03 알자 코포레이션 카테터 주입가능한 데포 조성물 및 그의 용도
BR0206984A (pt) * 2001-11-14 2004-02-03 Alza Corp Composições de depósito injetáveis e uso destas
US20070196415A1 (en) * 2002-11-14 2007-08-23 Guohua Chen Depot compositions with multiple drug release rate controls and uses thereof
US20040001889A1 (en) * 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
TWI353854B (en) 2002-06-25 2011-12-11 Alza Corp Short duration depot formulations
US8252303B2 (en) * 2002-07-31 2012-08-28 Durect Corporation Injectable depot compositions and uses thereof
MXPA05001244A (es) * 2002-07-31 2005-06-08 Alza Corp Composiciones de deposito de polimero multimodal inyectable y usos de las mismas.
JP2006508127A (ja) * 2002-11-06 2006-03-09 アルザ・コーポレーション 制御された放出性デポー剤配合物
ZA200505306B (en) * 2002-12-31 2006-09-27 Altus Pharmaceuticals Inc Complexes of protein crystals and ionic polymers
KR20050090430A (ko) * 2002-12-31 2005-09-13 알투스 파마슈티컬스 인코포레이티드 인간 성장 호르몬 결정 및 이것의 제조 방법
US20070184084A1 (en) * 2003-05-30 2007-08-09 Guohua Chen Implantable elastomeric caprolactone depot compositions and uses thereof
CA2527664A1 (en) * 2003-05-30 2004-12-16 Alza Corporation Implantable elastomeric depot compositions, uses thereof and method of manufacturing
US20050281879A1 (en) * 2003-11-14 2005-12-22 Guohua Chen Excipients in drug delivery vehicles
US20050106214A1 (en) * 2003-11-14 2005-05-19 Guohua Chen Excipients in drug delivery vehicles
US7812049B2 (en) * 2004-01-22 2010-10-12 Vicept Therapeutics, Inc. Method and therapeutic/cosmetic topical compositions for the treatment of rosacea and skin erythema using α1-adrenoceptor agonists
US20060142234A1 (en) * 2004-12-23 2006-06-29 Guohua Chen Injectable non-aqueous suspension
EP1976551A4 (en) * 2005-12-23 2009-12-30 Altus Pharmaceuticals Inc COMPOSITIONS COMPRISING COMPLEX PROTEIN CRYSTALS BY POLYCATIONS AND PROCESSING METHOD THEREOF
US7753078B2 (en) 2007-04-19 2010-07-13 Husco International Inc. Hybrid hydraulic joystick with an integral pressure sensor and an outlet port
US7753077B2 (en) 2007-04-19 2010-07-13 Husco International Inc. Hybrid hydraulic joystick for electrically operating valves
JP4889782B2 (ja) * 2008-12-24 2012-03-07 株式会社マルハニチロ食品 プロタミン及び／またはその塩と酸性高分子化合物とを含む生理活性複合体及びその用途
SG173112A1 (en) * 2009-01-28 2011-08-29 Smartcells Inc Conjugate based systems for controlled drug delivery
EP2643009A4 (en) * 2010-11-24 2015-04-01 Durect Corp COMPOSITION FOR THE RELEASE OF BIODEGRADABLE ACTIVE SUBSTANCES
JP6564369B2 (ja) 2013-12-09 2019-08-21 デュレクト コーポレイション 薬学的活性剤複合体、ポリマー複合体、ならびにこれらを伴う組成物及び方法
WO2021146215A1 (en) 2020-01-13 2021-07-22 Durect Corporation Sustained release drug delivery systems with reduced impurities and related methods
JP2024503402A (ja) 2021-01-12 2024-01-25 デュレクト コーポレーション 徐放性薬物送達システム及び関連の方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1282504A (fr) * 1954-06-03 1962-01-27 Novo Terapeutisk Labor As Procédé de production de suspensions stables d'insuline zinc-protamine
US3912807A (en) * 1974-04-18 1975-10-14 American Home Prod Treatment of diabetes using somatostatin and insulin
IN150740B (fi) * 1978-11-24 1982-12-04 Hoffmann La Roche
EP0032134B2 (en) * 1980-01-08 1993-10-13 Biogen, Inc. Dna sequences, recombinant dna molecules and processes for producing human interferon-alpha like polypeptides
ES506955A0 (es) * 1980-11-10 1983-02-01 Genentech Inc Un procedimiento para producir un polipeptido antiviral.
EP0082481B2 (en) * 1981-12-23 1990-09-12 Schering Corporation Stabilised alpha-interferon formulations and their preparation
US4605555A (en) * 1984-09-20 1986-08-12 Sun Star Kabushiki Kaisha Composition and method for treating keratosic disorder of skin and mucosa

Also Published As

Publication number Publication date
NZ223598A (en) 1989-12-21
DK582188D0 (da) 1988-10-19
ATE76580T1 (de) 1992-06-15
JPH0611712B2 (ja) 1994-02-16
OA09737A (en) 1993-11-30
US4853218A (en) 1989-08-01
DE3871407D1 (de) 1992-07-02
ZA881258B (en) 1988-08-23
FI93309C (fi) 1995-03-27
PT86810B (pt) 1992-05-29
WO1988006456A1 (en) 1988-09-07
EP0281299B1 (en) 1992-05-27
MY103212A (en) 1993-05-29
HU201881B (en) 1991-01-28
KR890700359A (ko) 1989-04-24
IL85523A0 (en) 1988-08-31
ES2032009T3 (es) 1993-01-01
IE61340B1 (en) 1994-11-02
FI893929A0 (fi) 1989-08-22
EP0281299A1 (en) 1988-09-07
DK582188A (da) 1988-10-19
NO173279B (no) 1993-08-16
JPH03500286A (ja) 1991-01-24
FI93309B (fi) 1994-12-15
AU1394688A (en) 1988-09-26
PT86810A (pt) 1988-03-01
AU608584B2 (en) 1991-04-11
FI893929L (fi) 1989-08-22
EP0375678A1 (en) 1990-07-04
NO173279C (no) 1993-11-24
MX9203328A (es) 1992-07-01
DK167048B1 (da) 1993-08-23
NO884596L (no) 1988-10-14
CA1316105C (en) 1993-04-13
NO884596D0 (no) 1988-10-14
HUT51902A (en) 1990-06-28
GR3005358T3 (fi) 1993-05-24
KR940001372B1 (ko) 1994-02-21
IE880480L (en) 1988-08-24

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