ZA87105B - Chemical compounds - Google Patents

Chemical compounds

Info

Publication number
ZA87105B
ZA87105B ZA87105A ZA87105A ZA87105B ZA 87105 B ZA87105 B ZA 87105B ZA 87105 A ZA87105 A ZA 87105A ZA 87105 A ZA87105 A ZA 87105A ZA 87105 B ZA87105 B ZA 87105B
Authority
ZA
South Africa
Prior art keywords
chemical compounds
compounds
chemical
Prior art date
Application number
ZA87105A
Other languages
English (en)
Inventor
Keith Mills
Colin David Eldred
Alexander William Oxford
Ian Harold Coates
David Edmund Bays
Colin Frederick Webb
Michael Dennis Dowle
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ZA87105B publication Critical patent/ZA87105B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA87105A 1986-01-08 1987-01-08 Chemical compounds ZA87105B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868600397A GB8600397D0 (en) 1986-01-08 1986-01-08 Chemical compounds

Publications (1)

Publication Number Publication Date
ZA87105B true ZA87105B (en) 1987-09-30

Family

ID=10591074

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA87105A ZA87105B (en) 1986-01-08 1987-01-08 Chemical compounds

Country Status (23)

Country Link
US (1) US4855314A (zh)
EP (1) EP0240096A1 (zh)
JP (1) JPS62228056A (zh)
KR (1) KR870007116A (zh)
CN (1) CN1030409A (zh)
AU (1) AU597325B2 (zh)
BE (1) BE1000071A4 (zh)
CH (1) CH672637A5 (zh)
DE (1) DE3700408A1 (zh)
DK (1) DK8787A (zh)
FI (1) FI870062A (zh)
FR (1) FR2595351B1 (zh)
GB (2) GB8600397D0 (zh)
HU (1) HU198685B (zh)
IL (1) IL81201A (zh)
IT (1) IT1205849B (zh)
LU (1) LU86732A1 (zh)
NL (1) NL8700026A (zh)
NO (1) NO870075L (zh)
NZ (1) NZ218868A (zh)
PH (1) PH24741A (zh)
PT (1) PT84075B (zh)
ZA (1) ZA87105B (zh)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8530507D0 (en) * 1985-12-11 1986-01-22 Glaxo Group Plc Chemical compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8724912D0 (en) 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
GB8823731D0 (en) * 1988-10-10 1988-11-16 Smith Kline French Lab Biologically active compounds
CA2064815C (en) * 1990-06-07 1999-11-16 Alan Duncan Robertson Therapeutic heterocyclic compounds
US5559246A (en) * 1990-10-15 1996-09-24 Pfizer Inc. Indole derivatives
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
US5559129A (en) * 1990-10-15 1996-09-24 Pfizer Inc Indole derivatives
US5607951A (en) * 1990-10-15 1997-03-04 Pfizer Inc Indole derivatives
AU651637B2 (en) * 1990-10-15 1994-07-28 Pfizer Inc. Indole derivatives
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
CA2061520C (en) * 1991-03-27 2003-04-22 Lawrence J. Daher Delivery system for enhanced onset and increased potency
HUT69705A (en) * 1991-11-25 1995-09-28 Pfizer Indole derivatives
TW288010B (zh) * 1992-03-05 1996-10-11 Pfizer
US6380233B1 (en) 1992-04-07 2002-04-30 Pfizer Inc Indole derivatives as 5-HT1 agonists
CZ281763B6 (cs) 1992-04-07 1997-01-15 Pfizer Inc. Indolové deriváty představující 5-HT1 agonisty, způsob jejich přípravy, farmaceutické prostředky obsahující tyto látky, jejich použití a meziprodukty postupu přípravy
GB9207930D0 (en) * 1992-04-10 1992-05-27 Pfizer Ltd Indoles
SK278182B6 (en) * 1992-04-10 1996-03-06 Pfizer Acylaminoindole derivatives as 5-ht1 agonists, method of their preparation and pharmaceutical compositions containing these matters their use and semifinished products of preparation proces
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
TW251284B (zh) * 1992-11-02 1995-07-11 Pfizer
FR2707639B1 (fr) * 1993-06-30 1995-10-13 Pf Medicament Nouveaux composés indoliques dérivés d'arylamines comme ligands sélectifs des récepteurs 5HT1D et 5HT1B.
ES2070772B1 (es) * 1993-08-09 1996-02-16 Pfizer Derivados de acilaminoindol
HUT75646A (en) * 1993-08-31 1997-05-28 Pfizer 5-arylindole derivatives and pharmaceutical compositions containing them
US5468768A (en) * 1994-01-06 1995-11-21 Bristol-Myers Squibb Company Antimigraine derivatives of indolylcycloalkanylamines
GB9417310D0 (en) 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
FR2749846B1 (fr) * 1996-06-17 1998-09-11 Pf Medicament Sel de methanesulfonate d'une arylpiperazine derivee de tryptamine et ses solvates pour usage pharmaceutique
US5994352A (en) * 1998-11-13 1999-11-30 Pfizer Inc. 5-arylindole derivatives
WO2002016319A1 (en) * 2000-08-21 2002-02-28 Pacific Corporation Novel thiourea compounds and the pharmaceutical compositions containing the same
BRPI0312174B1 (pt) 2002-06-21 2018-10-09 Suven Life Sciences Ltd composto, composição farmacêutica, uso de um composto, processo para a preparação de um composto, novo intermediário e processo para a preparação de um novo intermediário
RU2320663C2 (ru) * 2002-06-21 2008-03-27 Сувен Лайф Сайенсиз Лимитед Новые арилалкилиндолы с аффинностью к серотониновым рецепторам, пригодные в качестве лекарственных средств, способ их получения и содержащие их фармацевтические композиции
DE60317333T2 (de) * 2002-06-21 2008-08-28 Suven Life Sciences Ltd. Tetracyklische arylsulfonylindole mit affinität zum serotonin rezeptor
PT1581492E (pt) * 2002-11-28 2008-09-19 Suven Life Sciences Ltd Indoles n-arilsulfonil-3-substituídos possuindo afinidade de receptor de serotonina, processo para a sua preparação e composição farmacêutica contendo os mesmos
CN1720227A (zh) 2002-11-28 2006-01-11 苏文生命科学有限公司 N-芳基磺酰基-3-氨基烷氧基吲哚
CN100378109C (zh) * 2002-12-18 2008-04-02 苏文生命科学有限公司 具有5-羟色胺受体亲和性的四环3-取代的吲哚类化合物
WO2004056769A2 (en) * 2002-12-20 2004-07-08 Ciba Specialty Chemicals Holding Inc. Synthesis of amines and intermediates for the synthesis thereof
BRPI0713653A2 (pt) * 2006-06-12 2012-10-23 Novartis Ag processo para a preparação de sais de n-hidróxi-3-[4-[[[2-(2-metil-1h-indol-3-il)etil]amino]metil ]fenil]-2e-2propenamida

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3472870A (en) * 1966-08-29 1969-10-14 Mead Johnson & Co Sulfonamidotryptamines
FR2334358A1 (fr) * 1975-12-12 1977-07-08 Sogeras Nouveaux medicaments derives de l'indole
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
AU550010B2 (en) * 1980-08-12 1986-02-27 Glaxo Group Limited 5-tryptaminoacetamides, carbamates and ureas
HU196752B (en) * 1983-12-06 1989-01-30 Glaxo Group Ltd Process for production of medical compositions containing indole-derivatives and these compounds
GB8332437D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
GB8332434D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Production of chemical compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
BE1000071A4 (fr) 1988-02-02
PT84075B (pt) 1989-07-31
CN1030409A (zh) 1989-01-18
NO870075D0 (no) 1987-01-08
KR870007116A (ko) 1987-08-14
FR2595351A1 (fr) 1987-09-11
LU86732A1 (fr) 1988-02-02
PH24741A (en) 1990-10-01
GB8600397D0 (en) 1986-02-12
DK8787D0 (da) 1987-01-08
FR2595351B1 (fr) 1990-07-13
GB2185020A (en) 1987-07-08
NL8700026A (nl) 1987-08-03
GB2185020B (en) 1990-05-16
NZ218868A (en) 1990-04-26
FI870062A0 (fi) 1987-01-08
GB8700382D0 (en) 1987-02-11
AU597325B2 (en) 1990-05-31
AU6742087A (en) 1987-07-09
IT8747507A0 (it) 1987-01-08
EP0240096A1 (en) 1987-10-07
DK8787A (da) 1987-07-09
JPS62228056A (ja) 1987-10-06
FI870062A (fi) 1987-07-09
CH672637A5 (zh) 1989-12-15
IL81201A0 (en) 1987-08-31
HUT46891A (en) 1988-12-28
HU198685B (en) 1989-11-28
US4855314A (en) 1989-08-08
DE3700408A1 (de) 1987-07-09
NO870075L (no) 1987-07-09
PT84075A (en) 1987-02-01
IT1205849B (it) 1989-03-31
IL81201A (en) 1991-06-10

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