ZA85656B - Asymmetrical alkyl diphenylalkylaminoalkyl esters of 1,4-dihydro-2,6-dimethyl-pyridine-3,5-dicarboxylic acid - Google Patents

Asymmetrical alkyl diphenylalkylaminoalkyl esters of 1,4-dihydro-2,6-dimethyl-pyridine-3,5-dicarboxylic acid

Info

Publication number
ZA85656B
ZA85656B ZA85656A ZA85656A ZA85656B ZA 85656 B ZA85656 B ZA 85656B ZA 85656 A ZA85656 A ZA 85656A ZA 85656 A ZA85656 A ZA 85656A ZA 85656 B ZA85656 B ZA 85656B
Authority
ZA
South Africa
Prior art keywords
diphenylalkylaminoalkyl
dihydro
pyridine
esters
dimethyl
Prior art date
Application number
ZA85656A
Other languages
English (en)
Inventor
Dante Nardi
Amedeo Leonardi
Gabriele Graziani
Giorgio Bianchi
Original Assignee
Recordati Chem Pharm
Chemical & Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10556581&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA85656(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Recordati Chem Pharm, Chemical & Pharmaceutical Co filed Critical Recordati Chem Pharm
Publication of ZA85656B publication Critical patent/ZA85656B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
ZA85656A 1984-02-14 1985-01-28 Asymmetrical alkyl diphenylalkylaminoalkyl esters of 1,4-dihydro-2,6-dimethyl-pyridine-3,5-dicarboxylic acid ZA85656B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848403866A GB8403866D0 (en) 1984-02-14 1984-02-14 Diphenylalkylaminoalkyl esters

Publications (1)

Publication Number Publication Date
ZA85656B true ZA85656B (en) 1985-08-28

Family

ID=10556581

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA85656A ZA85656B (en) 1984-02-14 1985-01-28 Asymmetrical alkyl diphenylalkylaminoalkyl esters of 1,4-dihydro-2,6-dimethyl-pyridine-3,5-dicarboxylic acid

Country Status (29)

Country Link
US (3) US4705797A (da)
EP (1) EP0153016B1 (da)
JP (1) JPS60199874A (da)
KR (1) KR910005231B1 (da)
AR (1) AR240804A1 (da)
AT (1) ATE52772T1 (da)
AU (1) AU570534B2 (da)
BR (1) BR1101167A (da)
CA (1) CA1277666C (da)
DE (2) DE10199007I2 (da)
DK (1) DK160985C (da)
DZ (1) DZ748A1 (da)
EG (1) EG17772A (da)
ES (1) ES540385A0 (da)
FI (1) FI83954C (da)
GB (1) GB8403866D0 (da)
GR (1) GR850363B (da)
HU (1) HU194171B (da)
IE (1) IE57715B1 (da)
IL (1) IL74238A (da)
LU (1) LU90069I2 (da)
MX (1) MX156874A (da)
NL (1) NL970025I2 (da)
NO (2) NO166123C (da)
NZ (1) NZ210866A (da)
PH (1) PH20725A (da)
PT (1) PT79963B (da)
SG (1) SG48590G (da)
ZA (1) ZA85656B (da)

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IT1275532B (it) * 1995-07-14 1997-08-07 Recordati Chem Pharm Uso di derivati 1,4-diidropiridinici per la prevenzione e la terapia della degenerazione aterosclerotica della parete arteriosa
US5696139A (en) * 1995-05-12 1997-12-09 Recordati S.A., Chemical And Pharmaceutical Company Use of S-enantiomers of 1,4-dihydropyridine derivatives for treating heart failure
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US20060165788A1 (en) * 2004-09-09 2006-07-27 Wattanaporn Abramowitz Lercanidipine pH dependent pulsatile release compositions
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TW200616681A (en) * 2004-10-05 2006-06-01 Recordati Ireland Ltd Lercanidipine capsules
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AR052918A1 (es) * 2005-02-25 2007-04-11 Recordati Ireland Ltd Clorhidrato de lercanidipina amorfo
AR053023A1 (es) * 2005-02-25 2007-04-18 Recordati Ireland Ltd Base libre de lercanidipina, metodos para su preparacion y composiciones farmaceuticas que las contienen
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DE602006003877D1 (de) * 2006-05-24 2009-01-08 Cf Pharma Ltd Verfahren zur Herstellung von Lercanipidin
PT2046745E (pt) * 2006-08-04 2014-01-15 Recordati Ireland Ltd Processo para preparação de cloridrato de lercanidipina amorfo
US20080175872A1 (en) * 2006-09-28 2008-07-24 Osmotica Corp. Controlled Release Dosage Form Containing Lercanidipine and a Performance-enhancing Acid
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JPS5762257A (en) * 1980-10-03 1982-04-15 Yoshitomi Pharmaceut Ind Ltd 1,4-dihydropyridine-3,5-dicarboxylic acid ester or its salt
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NO854021L (no) * 1984-10-26 1986-04-28 Bayer Ag 1,4-dihydropyridin-hydroksyaminer og fremgangsmaate til fremstilling derav.
GB8503424D0 (en) * 1985-02-11 1985-03-13 Ici Plc Heterocyclic derivatives

Also Published As

Publication number Publication date
PT79963B (en) 1986-11-10
FI83954C (fi) 1991-09-25
DK160985B (da) 1991-05-13
JPH0517908B2 (da) 1993-03-10
NO166123B (no) 1991-02-25
KR910005231B1 (ko) 1991-07-24
NO166123C (no) 1991-06-05
DE3577703D1 (de) 1990-06-21
IE57715B1 (en) 1993-03-10
DE10199007I1 (de) 2001-04-12
PT79963A (en) 1985-03-01
EP0153016B1 (en) 1990-05-16
NL970025I2 (nl) 1998-01-05
AU3868985A (en) 1985-09-12
AR240804A2 (es) 1991-02-28
NO850521L (no) 1985-08-15
EP0153016A2 (en) 1985-08-28
DK63085A (da) 1985-08-15
CA1277666C (en) 1990-12-11
DZ748A1 (fr) 2004-09-13
GB8403866D0 (en) 1984-03-21
JPS60199874A (ja) 1985-10-09
DK63085D0 (da) 1985-02-12
HU194171B (en) 1988-01-28
GR850363B (da) 1986-02-06
MX156874A (es) 1988-10-08
EP0153016A3 (en) 1985-10-02
PH20725A (en) 1987-03-30
NL970025I1 (nl) 1997-09-01
US4968832A (en) 1990-11-06
DE10199007I2 (de) 2003-01-09
DK160985C (da) 1991-11-04
US4772621A (en) 1988-09-20
FI850535L (fi) 1985-08-15
IE850280L (en) 1985-08-14
LU90069I2 (fr) 1997-07-23
NO2000011I1 (no) 2000-10-17
ES8602664A1 (es) 1985-11-16
HUT37399A (en) 1985-12-28
BR1101167A (pt) 2004-08-17
US4705797A (en) 1987-11-10
ATE52772T1 (de) 1990-06-15
EG17772A (en) 1991-08-30
NZ210866A (en) 1988-07-28
FI850535A0 (fi) 1985-02-08
ES540385A0 (es) 1985-11-16
IL74238A (en) 1988-07-31
SG48590G (en) 1990-08-17
AR240804A1 (es) 1991-02-28
KR850005826A (ko) 1985-09-26
FI83954B (fi) 1991-06-14
AU570534B2 (en) 1988-03-17
IL74238A0 (en) 1985-05-31

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