ZA846107B - Derivatives of 4-phenyl-4-oxo-buten-2-oic acid,the process for preparing them,their application as medicaments and the compositions containing them - Google Patents

Derivatives of 4-phenyl-4-oxo-buten-2-oic acid,the process for preparing them,their application as medicaments and the compositions containing them

Info

Publication number
ZA846107B
ZA846107B ZA846107A ZA846107A ZA846107B ZA 846107 B ZA846107 B ZA 846107B ZA 846107 A ZA846107 A ZA 846107A ZA 846107 A ZA846107 A ZA 846107A ZA 846107 B ZA846107 B ZA 846107B
Authority
ZA
South Africa
Prior art keywords
preparing
compositions containing
buten
medicaments
oxo
Prior art date
Application number
ZA846107A
Other languages
English (en)
Inventor
Mario Bianchi
Fernando Barzaghi
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ZA846107B publication Critical patent/ZA846107B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
ZA846107A 1983-08-25 1984-08-07 Derivatives of 4-phenyl-4-oxo-buten-2-oic acid,the process for preparing them,their application as medicaments and the compositions containing them ZA846107B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22648/83A IT1169783B (it) 1983-08-25 1983-08-25 Derivati dell' acido 4-fenil 4-osso-buten 2-oico, loro procedimento di preparazione e loro applicazione come prodotti medicinali

Publications (1)

Publication Number Publication Date
ZA846107B true ZA846107B (en) 1986-03-26

Family

ID=11198831

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA846107A ZA846107B (en) 1983-08-25 1984-08-07 Derivatives of 4-phenyl-4-oxo-buten-2-oic acid,the process for preparing them,their application as medicaments and the compositions containing them

Country Status (19)

Country Link
US (1) US4594443A (fi)
EP (1) EP0134179B1 (fi)
JP (1) JPS6072843A (fi)
KR (1) KR850001724A (fi)
AT (1) ATE37533T1 (fi)
AU (1) AU565492B2 (fi)
CA (1) CA1216859A (fi)
DE (1) DE3474298D1 (fi)
ES (1) ES8505922A1 (fi)
FI (1) FI79524C (fi)
GR (1) GR80172B (fi)
HU (1) HU191714B (fi)
IL (1) IL72682A (fi)
IT (1) IT1169783B (fi)
MA (1) MA20210A1 (fi)
NZ (1) NZ209330A (fi)
PT (1) PT78942B (fi)
SU (1) SU1333233A3 (fi)
ZA (1) ZA846107B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1190340B (it) * 1986-06-06 1988-02-16 Roussel Maestretti Spa Derivati dell'acido 4-fenil 4-osso 2-butenoico,loro procedimento di preparazione e loro impiego come prodotti medicinali
DK49688A (da) * 1987-03-20 1988-09-21 Hoffmann La Roche Propiolophenonderivater
HU198292B (en) * 1987-09-25 1989-09-28 Richter Gedeon Vegyeszet Process for producing salicilates and pharmaceutical compositions comprising such active ingredient
HU211731B (en) * 1992-12-29 1996-02-28 Richter Gedeon Vegyeszet Process to prepare novel salicylic acid derivs. and pharmaceutical compns. contg. them
KR960703901A (ko) * 1993-08-19 1996-08-31 로즈 암스트롱 치환된 2(5H)푸라논, 2(5H)티오페논 및 2(5H)피롤론 유도체, 그의 제조 방법 및 엔도텔린 길항제로서의 그의 용도(Substituted 2(5H)Furanone, 2(5H)Thiophenone and 2(5H)Pyrrolone Derivatives, Their Preparation and Their Use as Endothelin antagonists)
US5922759A (en) * 1996-06-21 1999-07-13 Warner-Lambert Company Butenolide endothelin antagonists
WO1997008169A1 (en) * 1995-08-24 1997-03-06 Warner-Lambert Company Furanone endothelin antagonists
US5891892A (en) * 1996-10-29 1999-04-06 Warner-Lambert Company Small molecule biaryl compounds as inhibitors of endothelin converting enzyme
US20110067969A1 (en) * 2009-09-22 2011-03-24 Gm Global Technology Operations, Inc. Non-rotating clutch
PL3393530T3 (pl) * 2015-12-23 2022-12-05 Henkel Ag & Co. Kgaa Płyn do obróbki metali

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB588108A (en) * 1944-10-23 1947-05-14 Roche Products Ltd Manufacture of bacteriostatic substances
US2532579A (en) * 1946-08-06 1950-12-05 Du Pont Pest control compositions containing beta-acyl acrylates
US2562208A (en) * 1947-04-14 1951-07-31 Schering Corp Fungistatic composition
DE1282644B (de) * 1962-09-08 1968-11-14 Hoechst Ag Verfahren zur Herstellung von ungesaettigten ª€-Ketocarbonsaeureestern
DE2047806A1 (en) * 1970-09-29 1972-04-06 Dr Karl Thomae GmbH, 7950 Biberach 3-aroyl-acrylic acids - pharmaceutical intermediates prepd from acetophenones and glyoxylic acid derivs
DE2103749A1 (en) * 1971-01-27 1972-08-10 Dr. Karl Thomae GmbH, 7951 Biberach 3-acyl-acrylic acids prepn - from a ketone and glyoxylic acid (deriv)
DE2116293A1 (de) * 1971-04-02 1972-10-19 Cassella Farbwerke Mainkur Ag, 6000 Frankfurt Ketonderivate und Verfahren zu ihrer Herstellung
US3753997A (en) * 1971-06-07 1973-08-21 A Ash Trifluoromethly substituted-2,6-diphenyl-4-pyridyl carbinolamine antimalarials
US4017517A (en) * 1971-09-13 1977-04-12 Takeda Chemical Industries, Ltd. 2-(Trisubstituted benzoyl)-propionic acid and a method for the production thereof
BE788749A (fr) * 1971-09-13 1973-03-13 Takeda Chemical Industries Ltd Acide 3-(benzoyl trisubstitue)-propionique et son procede de preparation
BE795893A (fr) * 1972-02-28 1973-06-18 Unicler Derives de (methylene dioxy-3,4 phenyl)-1 dimethyl-4,4 pentene-1, leur preparation et leur application en therrapeutique
GB1392100A (en) * 1972-09-13 1975-04-23 Beecham Group Ltd Insecticides
FR2270856B1 (fi) * 1974-01-17 1978-07-21 Screen
US3940404A (en) * 1974-03-06 1976-02-24 The United States Of America As Represented By The Secretary Of The Army 2-Substituted phenyl-6-trifluoromethyl-4-pyridyl-carbinolamines
US3953463A (en) * 1974-03-06 1976-04-27 The United States Of America As Represented By The Secretary Of The Army 2-Aryl-6-trifluoromethyl-4-pyridyl-carbinolamine antimalarials
IT1210582B (it) * 1981-10-22 1989-09-14 Roussel Maestretti Spa Derivati di acido 4-fenil-4-ossobuten-2-oico dotati di proprieta'farmacologiche e composizioni farmaceutiche che li contengono
DE3228842A1 (de) * 1982-08-02 1984-02-02 Henkel Kgaa Sebosuppressive kosmetische mittel, enthaltend aryloxobutensaeurederivate sowie neue aryloxobutensaeurederivate

Also Published As

Publication number Publication date
EP0134179A3 (en) 1986-03-26
US4594443A (en) 1986-06-10
HUT34946A (en) 1985-05-28
EP0134179A2 (fr) 1985-03-13
FI843354A0 (fi) 1984-08-24
IT8322648A0 (it) 1983-08-25
JPS6072843A (ja) 1985-04-24
FI843354A (fi) 1985-02-26
FI79524B (fi) 1989-09-29
AU3235384A (en) 1985-02-28
AU565492B2 (en) 1987-09-17
IL72682A (en) 1987-10-20
HU191714B (en) 1987-03-30
KR850001724A (ko) 1985-04-01
FI79524C (fi) 1990-01-10
IL72682A0 (en) 1984-11-30
DE3474298D1 (en) 1988-11-03
EP0134179B1 (fr) 1988-09-28
SU1333233A3 (ru) 1987-08-23
CA1216859A (fr) 1987-01-20
PT78942A (fr) 1984-08-01
ES535411A0 (es) 1985-06-16
IT1169783B (it) 1987-06-03
MA20210A1 (fr) 1985-04-01
NZ209330A (en) 1987-09-30
ATE37533T1 (de) 1988-10-15
ES8505922A1 (es) 1985-06-16
PT78942B (fr) 1986-10-21
GR80172B (en) 1985-01-02

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