ES8401068A1 - Procedimiento para la preparacion de derivados de corinanteina, asi como de sus sales de adicion acida fisiologicamente inocuas. - Google Patents
Procedimiento para la preparacion de derivados de corinanteina, asi como de sus sales de adicion acida fisiologicamente inocuas.Info
- Publication number
- ES8401068A1 ES8401068A1 ES519743A ES519743A ES8401068A1 ES 8401068 A1 ES8401068 A1 ES 8401068A1 ES 519743 A ES519743 A ES 519743A ES 519743 A ES519743 A ES 519743A ES 8401068 A1 ES8401068 A1 ES 8401068A1
- Authority
- ES
- Spain
- Prior art keywords
- corynantheine
- derivatives
- preparation
- present
- medicaments
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE CORINANTEINA, DE FORMULA GENERAL (I), EN LA QUE R SIGNIFICA UN ATOMO DE HIDROGENO O ALCALINO, Y SUS SALES DE ADICION ACIDA FISIOLOGICAMENTE INOCUAS.COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, SE HIDROGENAN CATALITICAMENTE CORINANTEINA Y DIHIDROCORINANTEINA O MEZCLAS DE MATERIALES QUE CONTENGAN AMBAS SUSTANCIAS; SEGUNDA, LA TETRAHIDROCORINANTEINA OBTENIDA SE SAPONIFICA HASTA CONVERTIRLA EN ACIDO LIBRE; TERCERA, EL ACIDO LIBRE ES TRANSDUCIDO EN SUS ESTERES ALQUILOS O EN SUS SALES, MEDIANTE BASES INORGANICASY AMINAS FISIOLOGICAMENTE INOCUAS; Y POR ULTIMO, LAS SOLUCIONES DE REACCION OBTENIDAS SE HACEN REACCIONAR CON UN ACIDO INORGANICO FUERTE PARA LA FORMACION DE LAS SALES DE ACIDO CORRESPONDIENTES.DE APLICACION EN EL TRATAMIENTO DE PERTURBACIONES DEL RIEGO SANGUINEO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19823204960 DE3204960A1 (de) | 1982-02-12 | 1982-02-12 | Corynanthein-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8401068A1 true ES8401068A1 (es) | 1983-12-01 |
ES519743A0 ES519743A0 (es) | 1983-12-01 |
Family
ID=6155512
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES519743A Granted ES519743A0 (es) | 1982-02-12 | 1983-02-11 | Procedimiento para la preparacion de derivados de corinanteina, asi como de sus sales de adicion acida fisiologicamente inocuas. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4528289A (es) |
EP (1) | EP0086416A3 (es) |
JP (1) | JPS58159492A (es) |
CA (1) | CA1250582A (es) |
DE (1) | DE3204960A1 (es) |
ES (1) | ES519743A0 (es) |
IE (1) | IE830278L (es) |
MX (1) | MX7130E (es) |
ZA (1) | ZA83592B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU191454B (en) * | 1984-10-05 | 1987-02-27 | Richter Gedeon Vegyeszeti Gyar Rt.,Hu | Process for producing amides of oktahydro-indolo/2,3-a/quinolyzin-1-yl-alkanecarboxylic acids and pharmaceutically acceptable acid additional salts thereof |
US4624954A (en) * | 1985-12-20 | 1986-11-25 | American Home Products Corporation | 6,7,8,9-tetrahydro-10-methylpyrido[1,2-a]indol-9-amines and derivatives thereof, useful for the treatment of cognitive impairments |
US4665183A (en) * | 1985-12-20 | 1987-05-12 | American Home Products Corp. | Process for preparing 6,7,8,9-tetrahydro-10-methylpyrido[1,2-a]indol-9-amines and derivatives thereof useful for the treatment of cognitive impairments |
KR100392292B1 (ko) * | 2000-01-07 | 2003-07-22 | 주식회사 펩트론 | 5원환 융합 방향족 헤테로사이클릭 화합물을 유효성분으로 하는 hcv 치료제 조성물 |
US20020176876A1 (en) * | 2001-01-23 | 2002-11-28 | Harris Dennis H. | Topical therapeutic skin care system |
DE102005053241A1 (de) * | 2005-11-08 | 2007-05-16 | Schwabe Willmar Gmbh & Co | Extrakte aus der Rinde von Corynanthe-Arten und deren Verwendung sowie diese Extrakte enthaltende Arzneimittel, diätetische Lebensmittel und pharmazeutische Zubereitungen |
CN103804377A (zh) * | 2012-11-08 | 2014-05-21 | 复旦大学 | 柯楠因碱类化合物及其制备方法 |
US9199960B2 (en) | 2013-05-02 | 2015-12-01 | Frederick R. Ferri | Method and apparatus for processing herbaceous plant materials including the cannabis plant |
CN106008500A (zh) * | 2013-11-07 | 2016-10-12 | 复旦大学 | 柯楠因碱类化合物及其制备方法 |
CN104945405A (zh) * | 2014-03-27 | 2015-09-30 | 复旦大学 | 毛钩藤碱类似物及其合成方法与应用 |
CN104974154B (zh) * | 2014-04-01 | 2017-04-12 | 复旦大学 | 毛钩藤碱类似物及其在制备抗高血压药物中的用途 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL113232C (es) * |
-
1982
- 1982-02-12 DE DE19823204960 patent/DE3204960A1/de not_active Withdrawn
-
1983
- 1983-01-28 US US06/461,949 patent/US4528289A/en not_active Expired - Fee Related
- 1983-01-28 ZA ZA83592A patent/ZA83592B/xx unknown
- 1983-02-05 EP EP83101098A patent/EP0086416A3/de not_active Withdrawn
- 1983-02-08 MX MX8310481U patent/MX7130E/es unknown
- 1983-02-10 JP JP58019917A patent/JPS58159492A/ja active Pending
- 1983-02-11 CA CA000421466A patent/CA1250582A/en not_active Expired
- 1983-02-11 IE IE830278A patent/IE830278L/xx unknown
- 1983-02-11 ES ES519743A patent/ES519743A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
US4528289A (en) | 1985-07-09 |
IE830278L (en) | 1983-08-12 |
EP0086416A3 (de) | 1984-04-04 |
DE3204960A1 (de) | 1983-08-25 |
JPS58159492A (ja) | 1983-09-21 |
CA1250582A (en) | 1989-02-28 |
MX7130E (es) | 1987-07-08 |
ZA83592B (en) | 1983-11-30 |
EP0086416A2 (de) | 1983-08-24 |
ES519743A0 (es) | 1983-12-01 |
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