ES8301919A1 - Procedimiento para preparar derivados de indano - Google Patents

Procedimiento para preparar derivados de indano

Info

Publication number
ES8301919A1
ES8301919A1 ES499421A ES499421A ES8301919A1 ES 8301919 A1 ES8301919 A1 ES 8301919A1 ES 499421 A ES499421 A ES 499421A ES 499421 A ES499421 A ES 499421A ES 8301919 A1 ES8301919 A1 ES 8301919A1
Authority
ES
Spain
Prior art keywords
derivatives
pharmaceuticals
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES499421A
Other languages
English (en)
Other versions
ES499421A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES499421A0 publication Critical patent/ES499421A0/es
Publication of ES8301919A1 publication Critical patent/ES8301919A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE INDANO Y DE SUS SALES DE ADICION DE ACIDO FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R Y R SON ALQUILO C <003> R; R PUEDE SER UNO DE VARIOS TIPOS DE RADICALES; Y EL ANILLO A ESTA SUSTITUIDO. CONSISTE EN LA REACCION DE HIDROLISIS DE UN COMPUESTO DE FORMULA (II), EN LA QUE R , R Y A TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I) Y R ES ALQUILO C Q<003> . EL PRODUCTO OBTENIDO SE PUEDE HACER REACCIONAR CON UN COMPUESTO DE FORMULA R <024>X, EN LA QUE X ES EL RESTO ACIDO DE UN ESTER Y R ES EL MISMO QUE R EXCEPTO HIDROGENO. LA REACCION DE HIDROLISIS SE LLEVA A CABO EN UN DISOLVENTE INERTE, EN PRESENCIA DE UNA BASE, A LA TEMPERATURA DE EBULLICION DE LA MEZCLA. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTI-ANAFILACTICA.
ES499421A 1980-02-13 1981-02-13 Procedimiento para preparar derivados de indano Expired ES8301919A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1170/80A CH647235A5 (de) 1980-02-13 1980-02-13 4-(2,2-dialkylindan-1-yliden)piperidin derivate, ihre herstellung und verwendung.

Publications (2)

Publication Number Publication Date
ES499421A0 ES499421A0 (es) 1982-12-16
ES8301919A1 true ES8301919A1 (es) 1982-12-16

Family

ID=4204118

Family Applications (2)

Application Number Title Priority Date Filing Date
ES499421A Expired ES8301919A1 (es) 1980-02-13 1981-02-13 Procedimiento para preparar derivados de indano
ES515767A Expired ES8400406A1 (es) 1980-02-13 1982-09-16 Procedimiento para preparar derivados de indano.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES515767A Expired ES8400406A1 (es) 1980-02-13 1982-09-16 Procedimiento para preparar derivados de indano.

Country Status (23)

Country Link
US (1) US4351838A (es)
JP (1) JPS56135472A (es)
AT (1) AT381305B (es)
AU (1) AU544794B2 (es)
BE (1) BE887430A (es)
CA (1) CA1159070A (es)
CH (1) CH647235A5 (es)
DE (1) DE3104387A1 (es)
DK (1) DK61081A (es)
ES (2) ES8301919A1 (es)
FI (1) FI810344L (es)
FR (1) FR2475544A1 (es)
GB (1) GB2068956B (es)
IE (1) IE50816B1 (es)
IL (1) IL62115A (es)
IT (1) IT1142304B (es)
MY (1) MY8500167A (es)
NL (1) NL8100607A (es)
NZ (1) NZ196244A (es)
PH (1) PH16860A (es)
PT (1) PT72487B (es)
SE (1) SE8100946L (es)
ZA (1) ZA81986B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI74950C (fi) * 1980-09-18 1988-04-11 Ucb Sa Foerfarande foer framstaellning av terapeutiskt aktiva 2-/4-(difenylmetylen)-1-piperidinyl-aettiksyror.
DE3200304A1 (de) * 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
US5444302A (en) * 1992-12-25 1995-08-22 Hitachi, Ltd. Semiconductor device including multi-layer conductive thin film of polycrystalline material
TW200621677A (en) * 2004-09-21 2006-07-01 Astellas Pharma Inc Cyclic amine derivative or salt thereof
DE102005010000A1 (de) * 2005-03-04 2006-09-07 Merck Patent Gmbh Indane

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2916490A (en) * 1959-12-08 Ocjhs
SE371190B (es) * 1972-03-24 1974-11-11 Kabi Ab
DE1470055A1 (de) * 1963-12-07 1969-07-17 Merck Ag E Verfahren zur Herstellung von Piperidinderivaten
US3822310A (en) * 1971-01-21 1974-07-02 Merck & Co Inc Substituted indenyl acetic acids
US4251655A (en) * 1978-03-29 1981-02-17 Mcneilab, Inc. Substituted N-iminomethylpiperidines

Also Published As

Publication number Publication date
ATA64681A (de) 1986-02-15
DE3104387A1 (de) 1982-01-21
AU6716981A (en) 1981-08-20
AT381305B (de) 1986-09-25
IL62115A (en) 1985-04-30
MY8500167A (en) 1985-12-31
SE8100946L (sv) 1981-08-14
GB2068956A (en) 1981-08-19
NZ196244A (en) 1983-09-30
FR2475544A1 (fr) 1981-08-14
JPS56135472A (en) 1981-10-22
US4351838A (en) 1982-09-28
FR2475544B1 (es) 1983-08-19
CA1159070A (en) 1983-12-20
BE887430A (fr) 1981-08-10
PH16860A (en) 1984-03-22
PT72487A (en) 1981-03-01
IE810265L (en) 1981-08-13
ES499421A0 (es) 1982-12-16
IE50816B1 (en) 1986-07-23
ZA81986B (en) 1982-09-29
ES515767A0 (es) 1983-11-01
GB2068956B (en) 1983-09-28
IL62115A0 (en) 1981-03-31
FI810344L (fi) 1981-08-14
CH647235A5 (de) 1985-01-15
ES8400406A1 (es) 1983-11-01
IT8147775A0 (it) 1981-02-12
AU544794B2 (en) 1985-06-13
NL8100607A (nl) 1981-09-16
PT72487B (en) 1982-06-25
DK61081A (da) 1981-08-14
IT1142304B (it) 1986-10-08

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